Edgewise Therapeutics, Inc. EWTX

39.34 (1.82) (4.42%) as of 25 Sep
Market cap
$4.4B
P/E
0.0×
Insider Buys alert about insiders buying in the last 12 month

Insider Decisions

Total buys 0.20
Total sells 19.50
in millions of $
Nov 25 Feb 26 May 26 Aug 26
Buy — 1 — — — — — — — — — —
Sell — 1 — 1 — 2 1 1 — 1 5 —
Insider Ownership 23.92%

Capital & Financial Ratios

Market Cap 4,410.00
Revenue —
Net Income (197.22)
Free Cash Flow (158.83)
Net Debt (460.71)
Current Ratio 16.24
Debt/Equity 0.00
P/E ratio 0.00
P/S ratio 0.00
P/B ratio 9.45
Past 5Y EPS Growth (49.00%)
This Y EPS Growth (26.01%)
Next Y EPS Growth 20.21%
Next 5Y EPS Growth (4.58%)
in millions of $

Dividends

Payout Ratio 0.00
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2023 Powerpack
2022 Powerpack
2021 Powerpack
predictions in italic, special payouts not included in total or ratios

Assets vs Liabilities

2023 2024 2025 Q'26
Cash 318 470 530 461
Receivables — — — —
Inventory — — — —
Other — — — 4
327 475 543 472
2023 2024 2025 Q'26
Payables 4 6 6 5
ST’ Debt — — — —
Other — — — 10
17 24 27 29
in millions of $

Compound Annual Growth

10y 5y 3y
Sales — — —
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 32.73% 14.63%

Revenue

Year
in millions of $ · fiscal quarters ending in the months shown

Operating Cash Flow

Mar Jun Sep Dec Year
’26 (43) (42) — — —
’25 (38) (33) (35) (39) (144)
’24 (29) (26) (27) (27) (109)
’23 (23) (20) (22) (27) (92)
’22 (13) (16) (12) (12) (53)
’21 (6) (10) (8) (9) (34)
in millions of $ · fiscal quarters ending in the months shown

Free Cash Flow

Mar Jun Sep Dec Year
’26 (43) (43) — — —
’25 (38) (33) (35) (39) (144)
’24 (29) (26) (28) (27) (110)
’23 (27) (21) (23) (27) (98)
’22 (13) (17) (13) (15) (58)
’21 (6) (10) (9) (9) (34)
in millions of $ · fiscal quarters ending in the months shown

EPS

Mar Jun Sep Dec Year
’26 (0.46) (0.53) — — —
’25 (0.43) (0.34) (0.39) (0.47) (1.63)
’24 (0.33) (0.34) (0.36) (0.42) (1.45)
’23 (0.36) (0.34) (0.41) (0.47) (1.57)
’22 (0.30) (0.32) (0.34) (0.31) (1.27)
’21 (4.37) (0.21) (0.26) (0.26) (1.14)
fiscal quarters ending in the months shown

Target Price Range

Analyst price targets

Recommendation Rating

1.3
1Buy 2 3Hold 4 5Sell
2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028
— — — — — 13.19 5.41 5.12 9.00 10.60

Analyst estimates 2026–2028

Powerpack
Low Price
— — — — — 40.49 20.71 12.46 38.12 30.48
High Price
— — — — 19 31 59 88 110 146
Employees
— — — — 0 0 0 0 0 0
Revenue/Emp
— — — — — — — — — —
Revenue
— — — — — — — — — —
Gross Margin
— — — — (17) (43) (68) (100) (134) (168)
EBT
— — — — 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
EBT Margin
— 0 — — (17) (43) (68) (100) (134) (168)
Net Income
— — — — 0 0 0 (8) (10) (5)
Depreciation
— — — — 0.00 0.00 0.00 0.00 0.00 0.00
Revenue/Sh
— — — — (23.17) (1.14) (1.27) (1.57) (1.45) (1.63)
Earnings/Sh
— — — — (19.80) (0.89) (0.98) (1.44) (1.18) (1.40)
Cash Flow/Sh
— — — — (0.27) (0.02) (0.10) (0.09) (0.01) 0.00
Capex/Sh
— — — — (20.08) (0.91) (1.09) (1.53) (1.19) (1.40)
Free CF/Sh
— — — — 171.58 7.31 6.47 5.00 4.97 5.07
Book Value/Sh
— — — — 1 38 54 64 92 103
Shares
— — — — — — — — — —
PE Ratio
— — — — — — — — — —
PS Ratio
— — — — — — — — — —
PB Ratio
— — — — — — — — — —
EV/Sales
— — — — — — — — — —
EV/FCF
— — — — (15) (34) (53) (92) (109) (144)
Op' Cash Flow
— — — — 0 (1) (6) (6) (1) 0
Capex
— — — — (15) (34) (58) (98) (110) (144)
FCF
— — — — 125 273 340 310 452 516
Working Cap'
— — — — — — — — — —
Total Debt
— — — — (129) (281) (352) (318) (470) (530)
Net Debt
— — — — 127 274 347 319 459 522
Sh' Equity
— — — — (26.11%) (20.56%) (20.74%) (28.33%) (32.37%) (32.29%)
ROA
— — — — 0.00% 0.00% 0.00% (16,355.41%) 0.00% 0.00%
ROIC
— — — — (14.21%) (35.53%) (21.78%) (30.10%) (34.40%) (34.19%)
ROE
predictions in italic, sparklines do not include predictions

All 10 years →

Edgewise Therapeutics, Inc. (EWTX) key facts

  • Edgewise Therapeutics, Inc. (EWTX) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • Edgewise Therapeutics, Inc. reported a net loss of $167.8 million, or a loss of $1.63 per share, for fiscal 2025.
  • As of September 25, 2026, EWTX traded at $39.34, a market capitalization of $4.4 billion.
  • Return on equity was −34.2% and debt-to-equity 0.00.

Source: company filings (standardised) and stockrow calculations.

Edgewise Therapeutics, Inc. (EWTX) Latest News

News by impact score

Fine-tune

25 Sep

3

Oppenheimer analysts say EDG-7500's differentiated drug profile could benefit Edgewise Therapeutics by strengthening its competitive position and potential upside in development, signaling a possible near-term catalyst for EWTX if trial progress validates the profile. Positive broker view on EDG-7500's distinctive profile could influence sentiment and create near-term catalysts for EWTX, contingent on future trial data.

22 Sep

4

Edgewise Therapeutics unveiled preclinical data on EDG-7500, a first-in-class cardiac sarcomere modulator targeting the Regulatory Light Chain (RLC). In preclinical models, EDG-7500 demonstrated diastolic-biased properties that improved cardiac relaxation while preserving systolic function and cardiac reserve. Early clinical observations in symptomatic hypertrophic cardiomyopathy (HCM) were consistent with these findings. A peer-reviewed MoA publication is expected later today. The company will host a live investor webcast at 8:30 a.m. ET to discuss the data. In the Phase 2 CIRRUS-HCM trial, EDG-7500 was generally safe and well tolerated with no significant changes in left ventricular ejection fraction; Edgewise plans to begin Phase 3 in Q4 2026, pursuing both obstructive and nonobstructive HCM. These results support advancing a diastolic-focused approach for heart failure. Diastolic-focused MoA and a near-term Phase 3 plan could substantially boost investor sentiment and the company's long-term pipeline potential.

2 Sep

3

CYTK's aficamten may bolster its HCM market position and growth outlook, with potential competitive effects on Edgewise Therapeutics' EWTX programs in the same space. Discussion of rival CYTK drug prospects signals moderate pressure on EWTX positioning in HCM.

6 Aug

3 earnings

Edgewise Therapeutics reported its second quarter 2026 financial results. Quarterly financial results disclose operational performance and cash position that can shift near-term market views.

13 Jul

4

Edgewise Therapeutics sold Sevasemten for up to $2.65 billion, strengthening its balance sheet and shifting focus to cardiovascular pipeline. The $2.65 billion asset sale bolsters finances and pivots company strategy to cardiovascular focus.

4

Servier completes the acquisition of Edgewise Therapeutics' muscular dystrophy business. Completion of muscular dystrophy business sale to Servier constitutes major strategic divestiture that will reshape Edgewise Therapeutics operations and investor positioning.

4

Servier completes the acquisition of Edgewise Therapeutics' muscular dystrophy business. Completion of muscular dystrophy business sale to Servier marks major asset divestiture affecting Edgewise Therapeutics operations.

4

Servier completes the acquisition of Edgewise Therapeutics' Muscular Dystrophy Business. Divestiture of muscular dystrophy business to Servier alters Edgewise Therapeutics' operational focus and financial position substantially.

25 Jun

4

Edgewise Therapeutics, Inc. (EWTX) price target raised to $59 after positive data from HCM clinical trial. Positive HCM trial data triggers price target increase to $59, marking major advance in company's lead program.

17 Jun

3

RBC affirms Edgewise Therapeutics as compelling cardiology story despite atrial fibrillation concerns. Analyst affirmation of core cardiology narrative offsets atrial fibrillation concerns without shifting long-term trajectory.

16 Jun

4

Edgewise Therapeutics reports improvements in heart drug trial. Positive heart drug trial results can drive major valuation gains and accelerate development for Edgewise Therapeutics.

4

Edgewise Therapeutics announced positive top-line data from its 12-week Phase 2 CIRRUS-HCM trial of EDG-7500 in patients with obstructive and nonobstructive hypertrophic cardiomyopathy. Positive Phase 2 results for lead asset EDG-7500 materially advance Edgewise's HCM program and strengthen its competitive outlook.

2 Jun

5

Edgewise Therapeutics (EWTX) stock reaches record high after $2.65B licensing deal with Servier. $2.65B Servier deal delivers transformative capital and validates pipeline with major upside to valuation and trajectory.

5

Servier acquires Edgewise Therapeutics muscular dystrophy business for $2.65bn. Sale of core muscular dystrophy business for $2.65bn triggers fundamental change in Edgewise operations and valuation.

5

Servier acquires Edgewise Therapeutics' muscular dystrophy business for $2.65 billion. The $2.65 billion acquisition delivers major capital and forces strategic restructuring at Edgewise.

1 Jun

5

Servier acquires Edgewise Therapeutics' muscular dystrophy business for $2.65B, sending EWTX stock to a record high. $2.65B sale of core business unit transforms Edgewise operations, valuation and future direction.

5

Servier enters muscular dystrophy space via potential $2.7B deal with Edgewise Therapeutics for rights to its pipeline assets. Potential $2.7B Servier deal delivers major non-dilutive capital and external validation to Edgewise's core muscular dystrophy programs.

4

Edgewise Therapeutics raised $1.55 billion, strengthening its cash position and eliminating a key overhang. Major capital raise of $1.55 billion directly bolsters Edgewise balance sheet and removes overhang, materially supporting future operations and reducing financing risk.

4

Servier acquires Edgewise Therapeutics' muscular dystrophy business. Sale of core muscular dystrophy assets constitutes major strategic divestiture that alters Edgewise's business focus and future trajectory.

4

Edgewise Therapeutics sells Sevasemten for up to $2.65 billion, strengthening balance sheet and shifting focus to cardiovascular pipeline. Sale of Sevasemten for up to $2.65 billion delivers major capital and redirects strategy to cardiovascular programs.

4

Servier acquires Edgewise Therapeutics' muscular dystrophy business. Sale of muscular dystrophy business to Servier constitutes major strategic divestiture for Edgewise.

14 May

4

A fund placed a $75 million bet on Edgewise Therapeutics (EWTX), a hair loss biotech stock that surged more than 500% since its IPO. Major fund's $75 million investment amid 500% post-IPO surge signals strong investor confidence, likely driving significant positive market sentiment and performance.

3

A hedge fund added $29 million to its position in Edgewise Therapeutics (EWTX), a cancer stock already up 700%, signaling strong conviction in its potential amid impressive gains. Hedge fund's $29 million addition to the 700%-gaining EWTX position boosts market sentiment and supports moderate positive trajectory influence.

8 May

3

RBC Capital Markets indicates Edgewise Therapeutics' update on EDG-7500 could drive share price gains. Analyst endorsement of EDG-7500 update expected to positively influence market sentiment and short-term performance.

7 May

4

Edgewise Therapeutics reported first quarter 2026 financial results and advanced clinical programs targeting muscular dystrophy and cardiovascular indications. Advancing clinical programs in muscular dystrophy and cardiovascular indications alongside financial results signals major pipeline progress with significant potential to alter company trajectory and investor sentiment.

5 May

5

Edgewise Therapeutics (EWTX) achieved a 'clear win' in a clinical area where Bristol Myers Squibb previously failed, highlighting strong results for its therapy. Success where Bristol Myers failed redefines Edgewise's competitive edge and propels its market trajectory.

30 Mar

3

JPMorgan raised its price target for Edgewise Therapeutics (EWTX) to $45 amid optimism for the EDG-7500 pipeline. Analyst price target increase to $45 reflects optimism on EDG-7500 pipeline, likely influencing investor sentiment and short-to-medium term stock performance moderately.

17 Mar

4

Edgewise Therapeutics (EWTX) stock significantly outperformed the market on Tuesday amid positive developments boosting investor sentiment. Stock topping the market signals major positive catalyst likely to enhance future performance and trajectory.

16 Mar

4

Edgewise Therapeutics (EWTX) valuation appears favorable following encouraging long-term results from the MESA study, highlighting potential for improved market positioning and investor confidence. Encouraging long-term MESA study results represent a major clinical milestone that could significantly enhance EWTX's pipeline prospects and stock valuation.

4

Edgewise Therapeutics (EWTX) shares climbed 6.4% after positive long-term sevasemten data in Becker muscular dystrophy patients, demonstrating sustained muscle preservation, strength gains, and favorable safety. Investors anticipate Phase 2 readout, Phase 3 initiation, and potential partnerships. Long-term positive sevasemten data validates drug efficacy in Becker MD, accelerating clinical progress and enhancing approval prospects.

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