Edgewise Therapeutics, Inc.

EWTX Healthcare Biotechnology

EPS
+2,846.5%
Free cash flow
−30.2%

Quarter to September 2026, against a year earlier

44.89 6.02 +15.49%
Market cap
$4.2B
P/E
4.9×
Fwd P/E
—
Dividend yield
—
F-score
n/a
Altman Z
n/a
Beneish M
n/a
Dividend safety
n/a

Insider Decisions last twelve months

Sold, $m 17.39
Trades a month
Jan 26 Apr 26 Jul 26 Oct 26
Buy — — — — — — — — — — — —
Sell — 1 — 2 1 1 — 1 5 — — —
Insider Ownership 24.75%

Capital & Financial Ratios $m

Size
Market Cap 4,220.00
Revenue ttm —
Net income ttm 1,009.60
Free cash flow ttm (202.28)
Net debt Q (1,743.89)
Valuation
P/E 4.85
Forward P/E —
Price / sales 0.00
Forward P/S Powerpack
Price / FCF 0.00
Price / book 2.99
Financial health
Current ratio Q 12.30 (at or above 1.5: strong)
Debt / equity Q 0.00 (at or below 0.5: strong)
Interest coverage Q (8.97)
Growth
Revenue growth Q —
Operating income growth Q +1.53% (above 0%: growing)
EPS, this year +666.80% (at or above 15%: strong)
EPS, next year A −120.73% (below 0%: weak)
Revenue, next year A —
EPS, past 5 yrs —
EPS, next 5 yrs A −6.35% (below 0%: weak)

Green and red mark values outside typical ranges; (Q) is the latest quarter, (A) analysts’ estimates. How we judge →

Valuation vs history

P/B against its own 10 years 58.13%
10-year low 10-year high

Dividends

Yield
—
Annual rate
—
Payout ratio
—

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 318 470 530 1,744
Receivables — — — —
Inventory — — — —
Other — — — —
327 475 543 1,772
2023 2024 2025 Q'26
Payables 4 6 6 10
ST’ Debt — — — —
Other — — — —
17 24 27 144

Compound Annual Growth %

10y 5y 3y
Sales — — —
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 32.73% 14.63%

Earnings Trends EPS, adjusted, against the consensus

EPS $

Mar Jun Sep Dec Year
’26 (0.46) (0.53) 9.65 — —
’25 (0.43) (0.34) (0.39) (0.47) (1.63)
’24 (0.33) (0.34) (0.36) (0.42) (1.45)
’23 (0.36) (0.34) (0.41) (0.47) (1.57)
’22 (0.30) (0.32) (0.34) (0.31) (1.27)
’21 (4.37) (0.21) (0.26) (0.26) (1.14)
Fiscal quarters ending in the months shown.

Revenue $m

Year
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (43) (42) (78) — —
’25 (38) (33) (35) (39) (144)
’24 (29) (26) (27) (27) (109)
’23 (23) (20) (22) (27) (92)
’22 (13) (16) (12) (12) (53)
’21 (6) (10) (8) (9) (34)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (43) (43) (78) — —
’25 (38) (33) (35) (39) (144)
’24 (29) (26) (28) (27) (110)
’23 (27) (21) (23) (27) (98)
’22 (13) (17) (13) (15) (58)
’21 (6) (10) (9) (9) (34)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.2
1Buy 2 3Hold 4 5Sell

Ten years at a glance

Ten-year view Analyst estimates Powerpack
Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 TTM Sep ’26 Trend 10 yrs 2026e 2027e 2028e Next 3/yr
Income, $m
Income, $m Revenue — — — — — — — — — — — — 31 31 72 +51.0%
Gross margin, % — — — — — — — — — — 0 —
EBT — — — — (17) (43) (68) (100) (134) (168) 1,165 +57.8%
EBT margin, % — — — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.0 pt
Net income — 0 — — (17) (43) (68) (100) (134) (168) 1,010 n/m
Per share, $
Per share, $ Revenue — — — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 n/m
Earnings — — — — (23.17) (1.14) (1.27) (1.57) (1.45) (1.63) 9.25 (41.2%)
Cash flow — — — — (19.80) (0.89) (0.98) (1.44) (1.18) (1.40) (1.85) (41.2%)
Capex — — — — (0.27) (0.02) (0.10) (0.09) (0.01) 0.00 0.00 (60.9%)
Free cash flow — — — — (20.08) (0.91) (1.09) (1.53) (1.19) (1.40) (1.86) (41.3%)
Book value — — — — 171.58 7.31 6.47 5.00 4.97 5.07 15.00 (50.5%)
Shares, m — — — — 1 38 54 64 92 103 107 +168.4%
Valuation, ×
Valuation, × P/E — — — — — — — — — — 0 —
P/S — — — — — — — — — — 0 —
P/B — — — — — — — — — — 0 —
EV/Sales — — — — — — — — — — 0 —
EV/FCF — — — — — — — — — — 0 —
Cash, $m
Cash, $m Operating cash flow — — — — (15) (34) (53) (92) (109) (144) (202) +57.9%
Capex — — — — 0 (1) (6) (6) (1) 0 0 +4.7%
Free cash flow — — — — (15) (34) (58) (98) (110) (144) (202) +57.6%
Balance, $m
Balance, $m Working capital — — — — 125 273 340 310 452 516 1,628 +32.7%
Net debt — — — — (129) (281) (352) (318) (470) (530) (1,744) +32.6%
Shareholders’ equity — — — — 127 274 347 319 459 522 1,633 +32.7%
Returns, %
Returns, % ROA — — — — (26.11) (20.56) (20.74) (28.33) (32.37) (32.29) 85.43 (6.2) pt
ROIC — — — — 0.00 0.00 0.00 (16,355.41) 0.00 0.00 0.00 0.0 pt
ROE — — — — (14.21) (35.53) (21.78) (30.10) (34.40) (34.19) 92.15 (20.0) pt
People
People Employees — — — — 19 31 59 88 110 146 — +50.4%
Revenue/emp, $m — — — — 0.00 0.00 0.00 0.00 0.00 0.00 — n/m
Negative figures in brackets.
estimates

All 10 years →

Fundamentals updated 6 Nov 2026

Edgewise Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
LEGN Legend Biotech Corporation Sponsored ADR $4.4B — (loss-making) — (loss-making) +51.90% (above 0%: growing) n/m −26.79% (below 0%: shrinking) 64.54% 14.37% Compare
EWTX Edgewise Therapeutics, Inc. $4.2B — (loss-making) — — n/m −30.24% (below 0%: shrinking) 0.00% 0.00%
DFTX Definium Therapeutics, Inc. $4.1B — (loss-making) — — n/m −78.31% (below 0%: shrinking) 0.00% 0.00% Compare
RLAY Relay Therapeutics, Inc. $3.7B — (loss-making) — (loss-making) −95.44% (below 0%: shrinking) n/m +2.13% (above 0%: growing) 100.00% (25,949.71%) Compare
XENE Xenon Pharmaceuticals Inc. $3.7B — (loss-making) — (loss-making) +100.70% (above 0%: growing) n/m −48.57% (below 0%: shrinking) 100.00% 0.00% Compare
ABCL AbCellera Biologics Inc. $3.6B — (loss-making) — (loss-making) −76.29% (below 0%: shrinking) n/m +151.98% (above 0%: growing) 100.00% (1,550.05%) Compare
TNGX Tango Therapeutics, Inc. $3.5B — (loss-making) — (loss-making) −100.00% (below 0%: shrinking) n/m −4.58% (below 0%: shrinking) 0.00% 0.00% Compare
IOVA Iovance Biotherapeutics, Inc. $3.5B — (loss-making) — (loss-making) +80.07% (above 0%: growing) n/m +89.72% (above 0%: growing) 0.00% (19.73%) Compare
ARQT Arcutis Biotherapeutics, Inc. $3.4B 119× 81.2× +45.05% (above 0%: growing) +16.67% (above 0%: growing) +1,171.89% (above 0%: growing) 91.34% 6.56% Compare
Median of peers $3.6B — — +45.05% — −1.22% 77.94% 0.00%

All 621 Biotechnology stocks →

Pay and ownership Proxy statement filed 23 April 2026

Chief executive’s pay

Year Total pay Actually paid $100 invested
2025 7.36m 7.87m 285.64
2024 7.60m 35.60m 307.34
2023 3.98m 9.61m 127.81

Ownership

Directors and executive officers, together 21.30%
Peter Thompson, M.D. 14.50%
OrbiMed Advisors LLC 14.40%
RA Capital Management, L.P. 9.70%
Baker Bros. Advisors LP 6.80%
Paradigm BioCapital Advisors LP 6.10%
BlackRock Inc. 5.40%
Novo Holdings A/S 5.20%
Total pay is as the Summary Compensation Table states it; actually paid revalues the year’s share awards at its end, as the SEC’s pay-versus-performance rule asks. $100 invested is what $100 in the company’s shares at the start of the earliest year shown was worth at each year’s end. Ownership is the proxy’s own table: the directors and officers as a group, and every holder of 5% or more. Read the proxy statement

Edgewise Therapeutics, Inc. (EWTX) Latest News

4 Nov

EWTX metrics, ten years each

stockrow.com/EWTX · Data as of Nov 6, 2026 · For information only; not investment advice. · © 2026 stockrow.com