Denali Therapeutics Inc.
DNLI Healthcare Biotechnology
Denali Therapeutics Inc.’s revenue for fiscal 2023 (year ended December 2023) was $330.5 million, up 204.7% from fiscal 2022.
- Revenue
- −94.0%
- EPS
- +150.3%
- Free cash flow
- −11.8%
- Total debt
- −1.89%
Quarter to September 2026, against a year earlier
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Denali Therapeutics Inc. (DNLI) Operating margin
Denali Therapeutics Inc.'s operating margin over the twelve months to 30 September 2026 was −2,349.0%, down 2349.0 percentage points from fiscal 2025 (0.00%). Over the past ten years it has ranged from −799.1% (fiscal 2019) to 18.7% (fiscal 2020); the current reading is higher than 91% of that period. That is below the Biotechnology industry median of 0.00% and below the Healthcare sector median of 0.00%.
Operating margin, annual
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Annual newest first
| Period | Operating margin | Change (points) |
|---|---|---|
| FY2025 | 0.00% | 0.00 |
| FY2024 | 0.00% | 59.51 |
| FY2023 | −59.5% | 254.65 |
| FY2022 | −314.2% | 293.62 |
| FY2021 | −607.8% | (626.47) |
| FY2020 | 18.7% | 817.79 |
| FY2019 | −799.1% | (763.20) |
| FY2018 | −35.9% | (35.90) |
| FY2017 | 0.00% | 0.00 |
| FY2016 | 0.00% | 0.00 |
Quarterly newest first
| Period | Operating margin | Change (points) |
|---|---|---|
| Sep 2026 | −713.0% | 2,909.14 |
| Jun 2026 | −3,622.1% | (3,622.11) |
| Mar 2026 | 0.00% | 0.00 |
| Dec 2025 | 0.00% | 0.00 |
| 35 more quarters | Free account |
Against its own ten years
Operating margin against peers
| Company | Operating margin |
|---|---|
| ELVN Enliven Therapeutics, Inc. compare | 0.00% |
| DYN Dyne Therapeutics, Inc. compare | 0.00% |
| CELC Celcuity, Inc. compare | 0.00% |
| VKTX Viking Therapeutics, Inc. compare | 0.00% |
| TARS Tarsus Pharmaceuticals, Inc. compare | −102.0% |
| IDYA IDEAYA Biosciences, Inc. compare | −1,267.4% |
| VRDN Viridian Therapeutics, Inc. compare | −1,781.4% |
| DNLI Denali Therapeutics Inc. | −2,349.0% |
| TLX Telix Pharmaceuticals Limited compare | — |
| Biotechnology industry median | 0.00% |
| Healthcare sector median | 0.00% |
| Market median | 0.00% |
What Operating margin is
EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.
EBIT ÷ Revenue
More on DNLI
- Revenue
- Net income
- EPS (diluted)
- EBITDA
- Free cash flow
- Operating cash flow
- Gross margin
- Net margin
- Free cash flow margin
- P/E ratio
- P/S ratio
- P/B ratio
- Price to free cash flow
- EV/EBITDA
- EV/Sales
- EV/FCF
- Return on equity
- Return on assets
- Return on invested capital
- Debt to equity
- Current ratio
- Total debt
- Shares outstanding
- Book value per share
- Revenue growth
- Piotroski F-score
- Altman Z-score
- The full statement