Denali Therapeutics Inc.

DNLI Healthcare Biotechnology

Denali Therapeutics Inc.’s revenue for fiscal 2023 (year ended December 2023) was $330.5 million, up 204.7% from fiscal 2022.

Revenue
−94.0%
EPS
+150.3%
Free cash flow
−11.8%
Total debt
−1.89%

Quarter to September 2026, against a year earlier

20.06 0.34 +1.72%
Market cap
$3.2B
P/E
0.0×
Fwd P/E
−7.7×
Dividend yield
—
F-score
4/9
Altman Z
13.78
Beneish M
n/a
Dividend safety
n/a

Denali Therapeutics Inc. (DNLI) Return on equity

Alert me on Return on equity

Denali Therapeutics Inc.'s return on equity over the twelve months to 30 September 2026 was −33.9%, up 11.8 percentage points from fiscal 2025 (−45.7%). Over the past ten years it has ranged from −47.5% (fiscal 2017) to 157.9% (fiscal 2016); the current reading is higher than 18% of that period. That is above the Biotechnology industry median of −50.1% and below the Healthcare sector median of −26.3%.

Return on equity, annual

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Annual newest first

Period Return on equity Change (points)
FY2025 −45.7% (8.29)
FY2024 −37.4% (23.39)
FY2023 −14.0% 18.51
FY2022 −32.5% (5.01)
FY2021 −27.5% (36.72)
FY2020 9.21% 51.18
FY2019 −42.0% (34.81)
FY2018 −7.16% 40.30
FY2017 −47.5% (205.31)
FY2016 157.9% 127.27

Against its own ten years

Low −47.5% High 157.9%
Ten-year median −27.5%
Current reading's percentile 18

Return on equity against peers

Company Return on equity
VRDN Viridian Therapeutics, Inc. compare 0.00%
TLX Telix Pharmaceuticals Limited compare 0.00%
ELVN Enliven Therapeutics, Inc. compare −15.3%
DNLI Denali Therapeutics Inc. −33.9%
IDYA IDEAYA Biosciences, Inc. compare −38.5%
DYN Dyne Therapeutics, Inc. compare −81.6%
VKTX Viking Therapeutics, Inc. compare −96.4%
TARS Tarsus Pharmaceuticals, Inc. compare −319.8%
CELC Celcuity, Inc. compare −1,433.7%
Biotechnology industry median −50.1%
Healthcare sector median −26.3%
Market median 0.51%

What Return on equity is

ROE shows how much profit a company earns for its shareholders on the equity they have in the business.

Annual: Net Income Allotted to Shareholders ÷ Average Common Equity; TTM: Net Income Allotted to Shareholders ÷ Average Common Equity (latest quarter)

The full definition of Return on equity →

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