Denali Therapeutics Inc.

DNLI Healthcare Biotechnology

Denali Therapeutics Inc.’s revenue for fiscal 2023 (year ended December 2023) was $330.5 million, up 204.7% from fiscal 2022.

Revenue
−94.0%
EPS
+150.3%
Free cash flow
−11.8%
Total debt
−1.89%

Quarter to September 2026, against a year earlier

20.31 0.59 +2.99%
Market cap
$3.2B
P/E
0.0×
Fwd P/E
−7.7×
Dividend yield
—
F-score
4/9
Altman Z
13.78
Beneish M
n/a
Dividend safety
n/a

Denali Therapeutics Inc. (DNLI) Net margin

Alert me on Net margin

Denali Therapeutics Inc.'s net margin over the twelve months to 30 September 2026 was −1,388.2%, down 1388.2 percentage points from fiscal 2025 (0.00%). Over the past ten years it has ranged from −740.7% (fiscal 2019) to 21.2% (fiscal 2020); the current reading is higher than 91% of that period. That is below the Biotechnology industry median of 0.00% and below the Healthcare sector median of 0.00%.

Net margin, annual

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Annual newest first

Period Net margin Change (points)
FY2025 0.00% 0.00
FY2024 0.00% 43.94
FY2023 −43.9% 256.62
FY2022 −300.6% 296.59
FY2021 −597.2% (618.34)
FY2020 21.2% 761.93
FY2019 −740.7% (712.68)
FY2018 −28.1% (28.06)
FY2017 0.00% 0.00
FY2016 0.00% 0.00

Quarterly newest first

Period Net margin Change (points)
Sep 2026 394.5% 3,933.66
Jun 2026 −3,539.2% (3,539.21)
Mar 2026 0.00% 0.00
Dec 2025 0.00% 0.00
35 more quarters

Against its own ten years

Low −740.7% High 21.2%
Ten-year median 0.00%
Current reading's percentile 4

Net margin against peers

Company Net margin
ELVN Enliven Therapeutics, Inc. compare 0.00%
DYN Dyne Therapeutics, Inc. compare 0.00%
CELC Celcuity, Inc. compare 0.00%
VKTX Viking Therapeutics, Inc. compare 0.00%
TARS Tarsus Pharmaceuticals, Inc. compare −102.9%
IDYA IDEAYA Biosciences, Inc. compare −1,149.6%
DNLI Denali Therapeutics Inc. −1,388.2%
VRDN Viridian Therapeutics, Inc. compare −1,724.1%
TLX Telix Pharmaceuticals Limited compare —
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 1.06%

What Net margin is

Net Profit Margin tells an investor how much of each unit of revenue ends up as profit for shareholders after all costs, interest and taxes.

Net Income Allotted to Shareholders ÷ Revenue

The full definition of Net margin →

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