Denali Therapeutics Inc.

DNLI Healthcare Biotechnology

Denali Therapeutics Inc.’s revenue for fiscal 2023 (year ended December 2023) was $330.5 million, up 204.7% from fiscal 2022.

Revenue
−94.0%
EPS
+150.3%
Free cash flow
−11.8%
Total debt
−1.89%

Quarter to September 2026, against a year earlier

20.06 0.34 +1.72%
Market cap
$3.2B
P/E
0.0×
Fwd P/E
−7.7×
Dividend yield
—
F-score
4/9
Altman Z
13.78
Beneish M
n/a
Dividend safety
n/a

Denali Therapeutics Inc. (DNLI) EBITDA

Alert me on EBITDA

Denali Therapeutics Inc.'s EBITDA for fiscal 2025 was −$554.4M, compared with −$514.7M in fiscal 2024. Over the twelve months to 30 September 2026 it was −$524.5M. Over the past ten years it has ranged from −$554.4M (fiscal 2025) to $71.3M (fiscal 2020) — the current reading is the lowest in ten years. Denali Therapeutics Inc. ranks 579th of 594 Biotechnology companies by EBITDA.

EBITDA, annual

Embed this chart

Annual newest first

Period EBITDA Change
FY2025 −$554.4M —
FY2024 −$514.7M —
FY2023 −$223.9M —
FY2022 −$332.0M —
FY2021 −$278.4M —
FY2020 $71.3M —
FY2019 −$210.2M —
FY2018 −$41.7M —
FY2017 −$86.3M —
FY2016 −$85.7M —

Quarterly newest first

Period EBITDA Change
Sep 2026 −$124.2M —
Jun 2026 −$128.4M —
Mar 2026 −$135.8M —
Dec 2025 −$136.1M —
35 more quarters

Against its own ten years

Low −$554.4M High $71.3M
Ten-year median −$210.2M
Current reading's percentile 9

EBITDA against peers

What EBITDA is

EBITDA shows what a company earns from its operations before interest, taxes and the non-cash charges for depreciation and amortization.

Reported line item

The full definition of EBITDA →

More on DNLI