Charles River Laboratories International, Inc.

CRL Healthcare Diagnostics & Research

Charles River Laboratories International, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $4.0 billion, down 0.85% from fiscal 2024. In the quarter to June 2026, revenue fell 2.72%, EPS fell 102.8%, free cash flow fell 12.2% and total debt rose 12.3%, each against the same quarter a year earlier. Member of the S&P 500; operating cash flow growth for three consecutive years; insiders bought in the last twelve months.

299.77 6.47 −2.11%
Market cap
$14.6B
P/E
0.0×
Fwd P/E
29.6×
Dividend yield
—
F-score
5/9
Altman Z
2.40
Beneish M
−3.11
Dividend safety
n/a

Insider Decisions trades per month

Total buys 0.01
Total sells 42.91
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — 1 — — — — — 1 —
Sell — — — — — — — 1 — 9 — 1
Insider Ownership 1.71%

Capital & Financial Ratios $m

Market Cap 14,620.00
Revenue 3,998.99
Net Income (236.30)
Free Cash Flow 370.61
Net Debt 2,427.96
Current Ratio 1.35
Debt/Equity 0.92
P/E ratio 0.00
Fwd P/E 29.60
P/S ratio 3.60
P/B ratio 5.06
Past 5Y EPS Growth —
This Y EPS Growth 10.66%
Next Y EPS Growth 12.53%
Next Y revenue growth (2.43%) (below 0%: weak)
Next 5Y EPS Growth 11.75%

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 83.63%
10-year low 10-year high
P/B against its own 10 years 75.60%
10-year low 10-year high
EV/Sales against its own 10 years 83.27%
10-year low 10-year high
EV/FCF against its own 10 years 89.02%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2026 Powerpack
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2017 Powerpack
predictions special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 277 195 214 192
Receivables 780 721 709 712
Inventory 380 279 299 346
Other 83 106 129 179
1,609 1,403 1,447 1,529
2023 2024 2025 Q'26
Payables 169 140 149 141
ST’ Debt — — — —
Other 203 194 222 223
1,055 994 1,120 1,135

Compound Annual Growth %

10y 5y 3y
Sales 11.41% 6.55% 0.33%
Cash Flow 9.17% 6.18% 5.98%
Earnings 0.00% 0.00% 0.00%
Book Value 15.70% 8.40% 2.07%

Revenue $m

Mar Jun Sep Dec Year
’26 996 1,004 — — —
’25 984 1,032 1,005 994 4,015
’24 1,012 1,026 1,010 1,003 4,050
’23 1,029 1,060 1,027 1,013 4,129
’22 914 973 989 1,100 3,976
’21 825 915 896 905 3,540
’20 707 683 743 791 2,924
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 41 180 — — —
’25 172 205 214 148 738
’24 130 194 252 159 735
’23 109 148 205 221 684
’22 103 149 133 235 620
’21 170 187 175 229 761
’20 69 162 177 138 547
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (15) 149 — — —
’25 112 169 178 59 518
’24 51 154 213 84 502
’23 3 81 140 143 365
’22 22 67 60 146 295
’21 142 140 119 130 532
’20 43 136 151 51 380
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.30) (0.03) — — —
’25 0.50 1.06 1.10 (5.62) (2.91)
’24 1.30 1.74 1.33 (4.22) 0.20
’23 2.01 1.89 1.69 3.62 9.22
’22 1.81 2.13 1.88 3.65 9.48
’21 1.20 1.72 2.01 2.67 7.60
’20 1.02 1.34 2.03 2.81 7.20
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.8
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low 65.70 75.25 96.70 103.00 95.58 243.37 181.36 161.65 176.48 91.86

Analyst estimates 2026–2028

Powerpack
High 89.18 119.05 139.72 153.39 257.88 460.21 376.78 262.00 275.00 205.00
People
People Employees 11,000 11,800 14,700 17,100 18,400 20,000 21,400 21,800 20,100 19,700
Revenue/emp, $m 0.15 0.16 0.15 0.15 0.16 0.18 0.19 0.19 0.20 0.20
Income, $m
Income, $m Revenue 1,681 1,858 2,266 2,621 2,924 3,540 3,976 4,129 4,050 4,015
Gross margin, % 38.30 37.73 37.07 36.56 36.72 37.70 36.79 36.39 32.88 32.96
EBT 223 297 282 304 447 481 623 581 93 (100)
EBT margin, % 13.26 15.99 12.43 11.60 15.29 13.58 15.67 14.08 2.30 (2.48)
Net income 156 125 229 254 365 399 493 480 25 (142)
Depreciation 127 131 162 198 235 266 304 314 577 568
Per share, $
Per share, $ Revenue 35.76 39.12 47.26 53.79 59.01 70.39 78.25 80.61 78.82 81.01
Earnings 3.29 2.60 4.72 5.17 7.35 7.77 9.57 9.27 0.20 (2.91)
Cash flow 6.74 6.70 9.20 9.87 11.03 15.13 12.19 13.35 14.30 14.88
Capex (1.18) (1.74) (2.92) (2.88) (3.36) (4.55) (6.39) (6.22) (4.53) (4.42)
Free cash flow 5.56 4.96 6.28 6.99 7.67 10.58 5.80 7.13 9.76 10.46
Book value 17.85 22.06 27.53 33.61 42.75 50.48 58.67 70.32 67.48 63.96
Shares, m 47 47 48 49 50 50 51 51 51 50
Valuation, ×
Valuation, × P/E 23.19 42.72 24.08 29.55 34.04 48.49 22.82 25.30 1,025.56 0.00
P/S 2.14 2.83 2.39 2.84 4.23 5.35 2.79 2.91 2.34 2.46
P/B 4.29 5.02 4.11 4.55 5.84 7.46 3.72 3.33 2.74 3.12
EV/Sales 2.80 3.36 3.04 3.47 4.83 6.05 3.41 3.48 2.85 2.94
EV/FCF 18.02 26.46 22.91 26.71 37.19 40.24 46.02 39.34 22.99 22.78
Cash, $m
Cash, $m Operating cash flow 317 318 441 481 547 761 620 684 735 738
Capex (55) (82) (140) (141) (167) (229) (325) (319) (233) (219)
Free cash flow 262 236 301 340 380 532 295 365 502 518
Balance, $m
Balance, $m Working capital 227 363 340 311 361 241 347 554 409 327
Total debt 1,235 1,145 1,668 1,888 1,980 2,664 2,708 2,647 2,240 2,136
Net debt 1,117 981 1,473 1,650 1,751 2,422 2,474 2,370 2,046 1,923
Shareholders’ equity 839 1,047 1,320 1,638 2,118 2,539 2,981 3,602 3,467 3,170
Returns, %
Returns, % ROA 6.48 4.37 6.67 5.90 7.15 6.25 6.65 6.01 0.13 (1.97)
ROIC 7.59 8.88 7.42 6.67 6.99 7.43 7.46 6.46 2.58 0.31
ROE 19.63 13.08 19.13 17.04 19.40 16.79 17.62 14.42 0.29 (4.35)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Charts ten years each

Charles River Laboratories International, Inc. vs peers in Diagnostics & Research (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
DGX Quest Diagnostics Incorporated $26.4B 24.6× 20.8× +10.21% (above 0%: growing) +14.74% (above 0%: growing) +5.28% (above 0%: growing) 33.75% 15.08% Compare
LH Labcorp Holdings Inc. $26.4B 26.2× 19.0× +5.78% (above 0%: growing) +28.42% (above 0%: growing) −42.01% (below 0%: shrinking) 29.80% 12.10% Compare
GH Guardant Health, Inc. $22.3B — (loss-making) — (loss-making) +44.33% (above 0%: growing) n/m −5.46% (below 0%: shrinking) 65.39% (38.55%) Compare
MEDP Medpace Holdings, Inc. $17.6B 35.6× 26.7× +17.24% (above 0%: growing) +36.39% (above 0%: growing) −3.03% (below 0%: shrinking) 71.36% 20.76% Compare
RVTY Revvity Inc. $17.3B 72.7× 37.5× +1.31% (above 0%: growing) +2.17% (above 0%: growing) +59.29% (above 0%: growing) 57.13% 12.24% Compare
CRL Charles River Laboratories International, Inc. $14.6B — (loss-making) 29.6× −2.72% (below 0%: shrinking) n/m −12.22% (below 0%: shrinking) 36.19% 11.94%
ICLR ICON PLC $13.5B 254× 23.8× +1.20% (above 0%: growing) −59.31% (below 0%: shrinking) +109.66% (above 0%: growing) 23.23% 6.68% Compare
QGEN QIAGEN N.V. $9.5B 23.6× 17.5× +0.28% (above 0%: growing) +7.94% (above 0%: growing) +30.45% (above 0%: growing) 63.62% 24.75% Compare
TWST Twist Bioscience Corporation $9.5B — (loss-making) — (loss-making) +23.24% (above 0%: growing) n/m −7.23% (below 0%: shrinking) 52.76% (30.65%) Compare
Median of peers $17.4B 30.9× 22.3× +8.00% +11.34% +1.13% 54.95% 12.17%

All 52 Diagnostics & Research stocks →

CRL metrics, ten years each

Charles River Laboratories International, Inc. (CRL) key facts

  • Concern: Charles River Laboratories International, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $4.0 billion, down 0.85% from fiscal 2024.
  • Concern: Charles River Laboratories International, Inc. reported a net loss of $142.2 million, or a loss of $2.91 per share, for fiscal 2025.
  • Charles River Laboratories International, Inc. (CRL) is a Diagnostics & Research company in the Healthcare sector, listed on the New York Stock Exchange.
  • As of October 16, 2026, CRL traded at $299.77, a market capitalization of $14.6 billion.
  • Trailing earnings are negative, so a P/E ratio is not meaningful; the stock trades at 3.6× sales.
  • Return on equity was −4.35% and debt-to-equity 0.92.
  • Its Piotroski F-score is 5 out of 9 and its Altman Z-score is 2.40 (grey zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

Charles River Laboratories International, Inc. (CRL) Latest News

stockrow.com/CRL · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com