Crescent Biopharma, Inc. CBIO

13.99 (0.25) (1.76%) as of 25 Sep
Market cap
$528.9M
P/E
0.0×
Insider Buys alert about insiders buying in the last 12 month

Insider Decisions

Total buys 30.61
Total sells 1.51
in millions of $
Nov 25 Feb 26 May 26 Aug 26
Buy — — 1 — — — — — — 1 — —
Sell — — — — — — — — 7 — — 7
Insider Ownership 0.00%

Capital & Financial Ratios

Market Cap 528.93
Revenue 1.22
Net Income (165.12)
Free Cash Flow (71.85)
Net Debt (171.59)
Current Ratio 9.66
Debt/Equity 0.00
P/E ratio 0.00
P/S ratio 350.63
P/B ratio 2.68
Past 5Y EPS Growth 15.18%
This Y EPS Growth 78.41%
Next Y EPS Growth (5.24%)
Next 5Y EPS Growth 37.95%
in millions of $

Dividends

Payout Ratio 0.00
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2023 0.00
0.24
2022 0.00
1.43
2021 Powerpack
2020 Powerpack
2019 Powerpack
2017 Powerpack
predictions in italic, special payouts not included in total or ratios

Assets vs Liabilities

2023 2024 2025 Q'26
Cash 42 35 213 172
Receivables — — 18 —
Inventory — — — —
Other — — — —
44 35 237 179
2023 2024 2025 Q'26
Payables 1 7 10 3
ST’ Debt — — — —
Other — 0 5 5
7 10 36 19
in millions of $

Compound Annual Growth

10y 5y 3y
Sales — 257.77% 110.67%
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value 17.50% 9.63% 67.85%

Revenue

Mar Jun Sep Dec Year
’26 1 — — — —
’25 — — — — 11
’23 — — — — 0
’22 — 0 — — 0
’21 1 0 0 0 1
’20 9 — 1 0 10
in millions of $ · fiscal quarters ending in the months shown

Operating Cash Flow

Mar Jun Sep Dec Year
’26 (9) (19) — — —
’25 (11) (16) (18) (27) (72)
’24 (11) (9) (8) 21 (6)
’23 (12) (7) (9) (8) (35)
’22 (14) (16) (9) (8) (46)
’21 (14) (14) (17) (13) (57)
’20 (4) (15) (12) (10) (39)
in millions of $ · fiscal quarters ending in the months shown

Free Cash Flow

Mar Jun Sep Dec Year
’26 (9) (18) — — —
’25 (11) (17) (18) (27) (72)
’24 (11) (9) (8) 21 (6)
’23 (12) (7) (9) (8) (35)
’22 (14) (16) (9) (8) (47)
’21 (14) (14) (17) (13) (58)
’20 (4) (15) (12) (10) (39)
in millions of $ · fiscal quarters ending in the months shown

EPS

Mar Jun Sep Dec Year
’26 (0.70) (0.74) — — —
’25 (19.62) (4.93) (1.27) (4.01) (12.81)
’24 (17.00) (16.00) (15.00) (11.00) (23.28)
’23 (17.00) (13.00) (14.00) (14.00) (58.00)
’22 (28.00) (25.00) (16.00) (19.00) (89.00)
’21 (28.00) (28.00) (34.00) (33.00) (123.00)
’20 (18.00) (32.00) (29.00) (32.00) (112.00)
fiscal quarters ending in the months shown

Target Price Range

Analyst price targets

Recommendation Rating

1.3
1Buy 2 3Hold 4 5Sell
2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028
370.00 382.00 829.00 264.00 182.00 141.00 51.00 111.00 14.00 9.81

Analyst estimates 2026–2028

Powerpack
Low Price
925.00 1,825.00 2,605.00 1,356.00 550.00 440.00 319.00 416.00 353.00 37.00
High Price
42 40 50 57 54 52 39 35 4 44
Employees
0 0 0 0 0 0 0 0 0 0
Revenue/Emp
0 — — — 10 1 0 0 — 11
Revenue
100.00% 0.00% 0.00% 0.00% 100.00% 100.00% 100.00% 100.00% — 100.00%
Gross Margin
(32) (33) (48) (58) (51) (63) (47) (37) (18) (152)
EBT
(171,944.86%) 0.00% 0.00% 0.00% (502.09%) (5,468.82%) (62,251.73%) (368,994.00%) 0.00% (1,401.16%)
EBT Margin
(32) (33) (48) (58) (51) (63) (47) (37) (18) (154)
Net Income
0 0 0 0 0 0 0 0 0 0
Depreciation
0.09 0.00 0.00 0.00 22.23 2.25 0.14 0.02 0.00 1.04
Revenue/Sh
(150.00) (113.00) (118.00) (134.00) (112.00) (123.00) (89.00) (58.00) (23.28) (12.81)
Earnings/Sh
(139.85) (101.25) (105.56) (120.17) (85.83) (111.74) (88.44) (55.07) (8.17) (6.87)
Cash Flow/Sh
(3.31) (1.00) (0.31) (0.33) (0.15) (0.03) (0.16) (0.03) 0.03 (0.09)
Capex/Sh
(143.16) (102.25) (105.86) (120.50) (85.98) (111.77) (88.60) (55.10) (8.14) (6.96)
Free CF/Sh
166.04 407.15 500.52 356.45 280.45 158.61 81.72 60.65 (20.17) 19.49
Book Value/Sh
0 0 0 0 0 1 1 1 1 10
Shares
0.00 — — — 0.00 0.00 0.00 0.00 — 0.00
PE Ratio
3.80 — — — 16.88 63.89 852.55 960.87 — 688.83
PS Ratio
3.78 — — — 1.34 0.91 3.56 4.48 — 0.62
PB Ratio
2.66 — — — 3.61 (13.15) 586.10 729.25 — (291.15)
EV/Sales
(3.06) — — — (0.94) 0.27 (2.26) (3.75) — 0.72
EV/FCF
(30) (30) (43) (52) (39) (57) (46) (35) (6) (72)
Op' Cash Flow
(1) 0 0 0 0 0 0 0 0 (1)
Capex
(30) (30) (43) (52) (39) (58) (47) (35) (6) (72)
FCF
34 119 204 152 126 79 42 37 25 201
Working Cap'
— — — 3 2 1 1 — 37 —
Total Debt
(40) (124) (210) (155) (135) (89) (48) (42) 3 (213)
Net Debt
35 120 205 154 128 82 43 38 (15) 203
Sh' Equity
(70.03%) (38.93%) (28.11%) (30.25%) (32.84%) (53.48%) (63.89%) (75.98%) (44.15%) (111.59%)
ROA
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
ROIC
(83.96%) (42.94%) (29.69%) (32.19%) (36.14%) (60.46%) (74.98%) (90.72%) (155.80%) (167.75%)
ROE
predictions in italic, sparklines do not include predictions

All 10 years →

Fiscal years to Dec 2025 · latest quarter Mar 2026

Crescent Biopharma, Inc. (CBIO) key facts

  • Crescent Biopharma, Inc. (CBIO) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of September 25, 2026, CBIO traded at $13.99, a market capitalization of $528.9 million.
  • Return on equity was −167.8% and debt-to-equity 0.00.

Source: company filings (standardised) and stockrow calculations.

Crescent Biopharma, Inc. (CBIO) Latest News

News by impact score

Fine-tune

30 Jul

3

Crescent Biopharma reported second quarter 2026 financial results and recent business highlights. Quarterly results and business updates supply performance data that can shift near-term investor views.

16 Jul

3

Crescent Biopharma closed its public offering of ordinary shares and pre-funded warrants, including full exercise of the underwriters' option to purchase additional shares. Offering supplies operating capital but increases share count and potential dilution.

14 Jul

3

Crescent Biopharma announces proposed public offering of ordinary shares and pre-funded warrants. Proposed share offering signals capital raise with likely share dilution affecting near-term valuation and funding runway.

29 Apr

3

Crescent Biopharma, Inc. (CBIO) reported first quarter 2026 financial results, including revenue, net loss, cash position updates, and recent business highlights such as pipeline advancements and partnerships. Quarterly financial results and business highlights moderately influence financial performance and investor sentiment without fundamentally altering long-term trajectory.

26 Feb

4

Crescent Biopharma, Inc. (CBIO) reported fourth quarter and full-year 2025 financial results alongside recent business highlights. Full-year financial results and business highlights significantly affect investor sentiment, valuation, and strategic outlook.

3

Crescent Biopharma, Inc. (CBIO) released its Q4 earnings snapshot, detailing key financial metrics for the quarter. Q4 earnings snapshots reveal financial performance that moderately influences stock price and investor sentiment.

18 Feb

4

Crescent Biopharma, Inc. (CBIO) announced dosing of the first patient in the ASCEND Phase 1/2 clinical trial evaluating CR-001 for advanced solid tumors. Advancing to first patient dosing in a Phase 1/2 trial marks a significant clinical milestone boosting investor sentiment and potential market performance for a biotech firm.

5 Feb

3

Crescent Biopharma, Inc. (CBIO) is set to present at the Guggenheim Emerging Outlook: Biotech Summit 2026. The event will showcase innovative biotech companies and provide insights into the industry's future. Crescent Biopharma aims to highlight its advancements and strategic initiatives during the summit, which could attract investor interest and enhance its market visibility. Participation in a prominent biotech summit may enhance visibility and investor interest but is not expected to fundamentally alter the company's trajectory.

30 Jan

3

Crescent Biopharma, Inc. (CBIO) has announced the granting of inducement awards to new employees as part of their recruitment strategy. These awards are designed to attract talent and align the interests of new hires with the company's long-term goals. The inducement awards consist of stock options and restricted stock units, which will vest over a specified period. This initiative reflects Crescent Biopharma's commitment to building a strong team to support its growth and development in the biopharmaceutical sector. The inducement awards may enhance talent acquisition and retention, impacting operational effectiveness and innovation.

5 Jan

4

Crescent Biopharma, Inc. has received regulatory clearances for Investigational New Drug (IND) applications for two of its products: CR-001, a bispecific antibody targeting PD-1 and VEGF, and CR-003, an antibody-drug conjugate targeting ITGB6. These developments are aimed at treating solid tumors, marking a significant step forward in the company's oncology pipeline. Regulatory clearances for new drug applications can significantly impact future product development and market positioning.

4

Kelun-Biotech received Investigational New Drug approval from China's NMPA for SKB105, an ITGB6-targeted antibody-drug conjugate, enabling clinical trials. IND approval for SKB105 advances CBIO's ADC pipeline into clinical development, boosting its oncology prospects and market positioning.

3

Kelun-Biotech has received Investigational New Drug (IND) approval from the National Medical Products Administration (NMPA) for its ITGB6-targeted antibody-drug conjugate, SKB105. This approval allows the company to initiate clinical trials for SKB105, which is designed to target specific cancer cells, potentially enhancing treatment efficacy. The IND approval marks a significant milestone for Kelun-Biotech as it advances its oncology pipeline. The IND approval for SKB105 may moderately influence Crescent Biopharma's competitive positioning in the oncology sector.

18 Dec

3

Crescent Biopharma, Inc. (CBIO) has announced the granting of inducement awards to new employees as part of its strategy to attract and retain talent. These awards consist of stock options and restricted stock units, aimed at incentivizing key personnel to contribute to the company's growth and success. The move reflects Crescent Biopharma's commitment to building a strong team to advance its biopharmaceutical initiatives. Inducement awards can enhance talent acquisition and retention, potentially impacting the company's operational effectiveness and innovation.

5 Dec

4

Crescent Biopharma, Inc. and Kelun-Biotech have entered into a strategic agreement to swap rights to certain cancer assets. This deal aims to enhance both companies' portfolios in oncology, allowing them to focus on their respective strengths and potentially accelerate the development of new treatments. The transaction reflects a growing trend in the biopharmaceutical industry where companies seek to optimize their asset bases through collaborations and exchanges. The asset swap is a significant strategic move that could enhance Crescent's competitive positioning and product pipeline in the oncology market.

4 Dec

4

Crescent Biopharma, Inc. has entered into a multimillion-dollar partnership with Kelun-Biotech to develop cancer drugs. This collaboration aims to leverage both companies' expertise in biopharmaceuticals to accelerate the development of innovative cancer therapies, potentially enhancing their market presence and product offerings. The partnership represents a significant strategic move that could enhance product innovation and market positioning in the competitive biopharmaceutical landscape.

4

Crescent Biopharma, Inc. (CBIO) has announced a transformative partnership with Kelun-Biotech, alongside a $185 million private placement. This collaboration aims to accelerate and expand the global pipeline of next-generation therapeutics targeting solid tumors, enhancing CBIO's position in the oncology market. The partnership and funding are expected to significantly enhance CBIO's product development and market positioning in oncology therapeutics.

4

Kelun-Biotech and Crescent Biopharma, Inc. (CBIO) have entered into a strategic partnership aimed at developing and commercializing innovative oncology therapeutics. This collaboration is expected to leverage both companies' expertise and resources to advance cancer treatment options, enhancing their positions in the oncology market. The partnership is likely to significantly impact Crescent Biopharma's future performance and market positioning in the oncology sector.

17 Nov

3

Crescent Biopharma, Inc. (CBIO) has announced the granting of inducement awards to new employees as part of their hiring strategy. These awards, which include stock options and restricted stock units, are intended to attract talent and align the interests of employees with those of shareholders. The company aims to enhance its workforce to support ongoing and future projects in the biopharmaceutical sector. Inducement awards can positively influence talent acquisition and retention, impacting operational effectiveness.

6 Nov

4

Crescent Biopharma, Inc. (CBIO) reported its financial results for the third quarter of 2025, highlighting significant revenue growth and advancements in its product pipeline. The company achieved a notable increase in net income compared to the previous quarter, driven by successful product launches and strategic partnerships. Recent developments include progress in clinical trials and regulatory approvals, positioning CBIO favorably in the competitive biopharmaceutical landscape. Management expressed optimism about future growth prospects and ongoing initiatives aimed at expanding market reach. Significant revenue growth and advancements in product pipeline indicate a strong potential for future performance and market positioning.

3

Crescent Biopharma, Inc. reported its Q3 earnings, highlighting a significant increase in revenue compared to the previous quarter. The company attributed this growth to successful product launches and expanding market presence. However, expenses also rose, impacting overall profitability. Management expressed optimism about future developments and ongoing projects aimed at enhancing product offerings. The earnings report reflects a mixed performance, with both positive growth indicators and challenges ahead. The earnings report indicates growth potential but also highlights rising expenses that could limit overall profitability.

5 Nov

3

Crescent Biopharma, Inc. (CBIO) announced its participation in several investor conferences scheduled for November. The company aims to engage with investors and discuss its strategic initiatives and developments in the biopharmaceutical sector. These conferences provide a platform for Crescent Biopharma to showcase its progress and future plans to potential investors. Participation in investor conferences can moderately influence investor sentiment and provide opportunities for funding and partnerships.

4 Nov

4

Crescent Biopharma, Inc. will present preclinical data for its bispecific antibody CR-001, which targets PD-1 and VEGF, at the Society for Immunotherapy of Cancer’s 40th Annual Meeting. This presentation highlights the company's ongoing research and development efforts in immunotherapy. The presentation of preclinical data at a significant conference could enhance Crescent Biopharma's visibility and credibility in the competitive immunotherapy landscape.

17 Sep

4

Crescent Biopharma, Inc. (NASDAQ:CBIO) has attracted significant interest from institutional investors, holding a 36% stake in the company. This level of investment indicates confidence in Crescent Biopharma's potential and future growth prospects, suggesting a positive outlook for the company's market performance. The substantial institutional stake indicates strong investor confidence, likely influencing future performance and market dynamics.

28 Aug

3

Crescent Biopharma, Inc. (CBIO) announced its participation in several investor conferences scheduled for September. The company aims to engage with investors and provide updates on its strategic initiatives and product pipeline. These conferences are expected to enhance visibility and foster relationships with potential investors. Participation in investor conferences can moderately influence market sentiment and investor interest in the company's future prospects.

31 Jul

4

Crescent Biopharma, Inc. (CBIO) reported its financial results for the second quarter of 2025, highlighting key business developments and financial metrics. The company showcased growth in revenue and advancements in its product pipeline, indicating a positive trajectory in its operations. Management emphasized strategic initiatives aimed at enhancing market presence and addressing unmet medical needs. The report reflects the company's commitment to innovation and shareholder value. Significant advancements in product pipeline and strategic initiatives are likely to impact future performance and investor sentiment.

3

Crescent Biopharma, Inc. reported its Q2 earnings, highlighting a significant increase in revenue compared to the previous quarter. The company attributed this growth to successful product launches and expanding market presence. However, expenses also rose, impacting overall profitability. Management expressed optimism about future growth driven by ongoing research and development efforts. The outlook for the next quarter remains cautiously positive, with expectations for continued revenue growth and strategic initiatives aimed at enhancing operational efficiency. Revenue growth and product launches indicate a moderately noticeable influence on financial performance.

8 Jul

3

Crescent Biopharma, Inc. has appointed Jan Pinkas, Ph.D., as its new Chief Scientific Officer. Dr. Pinkas brings extensive experience in drug development and a strong background in biopharmaceutical research, which is expected to enhance the company's scientific capabilities and innovation efforts. His appointment is part of Crescent Biopharma's strategy to strengthen its leadership team and advance its pipeline of therapeutic candidates. The appointment of a new Chief Scientific Officer may influence product innovation and operational aspects but is not expected to drastically change the company's overall trajectory.

5 Jun

4

GlycoMimetics, Inc. stockholders have approved the proposed merger with Crescent Biopharma along with all related proposals. This decision marks a significant step in the company's strategic direction and future operations. The merger is a major strategic move that could significantly alter the company's trajectory and investor sentiment.

19 Feb

3

GlycoMimetics, Inc. is highlighted as a penny stock to watch, with a market cap of $18.71 million and a focus on therapies for cancers and inflammatory diseases. The company reported a net loss of $37.88 million for 2024 and faces challenges, including executive departures and a planned merger with Crescent Biopharma, Inc. It has received a Nasdaq extension to comply with listing requirements but risks delisting if it fails to meet the minimum bid price by June 2025. Despite being debt-free, financial uncertainties loom for potential investors. Financial uncertainties and executive changes may moderately influence GlycoMimetics' future performance.

14 Jan

4

GlycoMimetics, Inc. (GLYC) has announced plans to merge with Crescent Biopharma, aiming to enhance their combined capabilities in drug development. The merger is expected to create a stronger entity focused on advancing innovative therapies, particularly in the field of oncology. Both companies believe that this strategic move will provide greater resources and expertise to accelerate their research and development efforts. The transaction is anticipated to close in the coming months, pending regulatory approvals and other customary closing conditions. The merger is a significant strategic move that could enhance GlycoMimetics' capabilities and market position in drug development.

stockrow.com/CBIO · Data as of Mar 31, 2026 · For information only; not investment advice. · © 2026 stockrow.com