Saturday 17 October 2026
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Crescent Biopharma, Inc.
CBIO Healthcare Biotechnology
Crescent Biopharma, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $10.8 million, up 108,340.0% from fiscal 2023. In the quarter to June 2026, revenue grew 1,038,900.0%, EPS grew 85.0% and free cash flow fell 7.04%, each against the same quarter a year earlier. Insiders bought in the last twelve months.
11.84
0.64
−5.13%
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Target Price Range
Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Trend | 2026e | 2027e | 2028e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Price, $ | |||||||||||||||
| Price, $ | Low | 370.00 | 382.00 | 829.00 | 264.00 | 182.00 | 141.00 | 51.00 | 111.00 | 14.00 | 9.81 |
Analyst estimates 2026–2028 Powerpack |
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| High | 925.00 | 1,825.00 | 2,605.00 | 1,356.00 | 550.00 | 440.00 | 319.00 | 416.00 | 353.00 | 37.00 | |||||
| People | |||||||||||||||
| People | Employees | 42 | 40 | 50 | 57 | 54 | 52 | 39 | 35 | 4 | 44 | ||||
| Revenue/emp, $m | 0.00 | 0.00 | 0.00 | 0.00 | 0.19 | 0.02 | 0.00 | 0.00 | 0.00 | 0.25 | |||||
| Income, $m | |||||||||||||||
| Income, $m | Revenue | 0 | — | — | — | 10 | 1 | 0 | 0 | — | 11 | ||||
| Gross margin, % | 100.00 | 0.00 | 0.00 | 0.00 | 100.00 | 100.00 | 100.00 | 100.00 | — | 100.00 | |||||
| EBT | (32) | (33) | (48) | (58) | (51) | (63) | (47) | (37) | (18) | (152) | |||||
| EBT margin, % | (171,944.86) | 0.00 | 0.00 | 0.00 | (502.09) | (5,468.82) | (62,251.73) | (368,994.00) | 0.00 | (1,401.16) | |||||
| Net income | (32) | (33) | (48) | (58) | (51) | (63) | (47) | (37) | (18) | (154) | |||||
| Depreciation | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||||
| Per share, $ | |||||||||||||||
| Per share, $ | Revenue | 0.09 | 0.00 | 0.00 | 0.00 | 22.23 | 2.25 | 0.14 | 0.02 | 0.00 | 1.04 | ||||
| Earnings | (150.00) | (113.00) | (118.00) | (134.00) | (112.00) | (123.00) | (89.00) | (58.00) | (23.28) | (12.81) | |||||
| Cash flow | (139.85) | (101.25) | (105.56) | (120.17) | (85.83) | (111.74) | (88.44) | (55.07) | (8.17) | (6.87) | |||||
| Capex | (3.31) | (1.00) | (0.31) | (0.33) | (0.15) | (0.03) | (0.16) | (0.03) | 0.03 | (0.09) | |||||
| Free cash flow | (143.16) | (102.25) | (105.86) | (120.50) | (85.98) | (111.77) | (88.60) | (55.10) | (8.14) | (6.96) | |||||
| Book value | 166.04 | 407.15 | 500.52 | 356.45 | 280.45 | 158.61 | 81.72 | 60.65 | (20.17) | 19.49 | |||||
| Shares, m | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 10 | |||||
| Valuation, × | |||||||||||||||
| Valuation, × | P/E | 0.00 | — | — | — | 0.00 | 0.00 | 0.00 | 0.00 | — | 0.00 | ||||
| P/S | 3.80 | — | — | — | 16.88 | 63.89 | 852.55 | 960.87 | — | 688.83 | |||||
| P/B | 3.78 | — | — | — | 1.34 | 0.91 | 3.56 | 4.48 | — | 0.62 | |||||
| EV/Sales | 2.66 | — | — | — | 3.61 | (13.15) | 586.10 | 729.25 | — | (291.15) | |||||
| EV/FCF | (3.06) | — | — | — | (0.94) | 0.27 | (2.26) | (3.75) | — | 0.72 | |||||
| Cash, $m | |||||||||||||||
| Cash, $m | Operating cash flow | (30) | (30) | (43) | (52) | (39) | (57) | (46) | (35) | (6) | (72) | ||||
| Capex | (1) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | (1) | |||||
| Free cash flow | (30) | (30) | (43) | (52) | (39) | (58) | (47) | (35) | (6) | (72) | |||||
| Balance, $m | |||||||||||||||
| Balance, $m | Working capital | 34 | 119 | 204 | 152 | 126 | 79 | 42 | 37 | 25 | 201 | ||||
| Total debt | — | — | — | 3 | 2 | 1 | 1 | — | 37 | — | |||||
| Net debt | (40) | (124) | (210) | (155) | (135) | (89) | (48) | (42) | 3 | (213) | |||||
| Shareholders’ equity | 35 | 120 | 205 | 154 | 128 | 82 | 43 | 38 | (15) | 203 | |||||
| Returns, % | |||||||||||||||
| Returns, % | ROA | (70.03) | (38.93) | (28.11) | (30.25) | (32.84) | (53.48) | (63.89) | (75.98) | (44.15) | (111.59) | ||||
| ROIC | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |||||
| ROE | (83.96) | (42.94) | (29.69) | (32.19) | (36.14) | (60.46) | (74.98) | (90.72) | (155.80) | (167.75) | |||||
Negative figures in brackets.
Fiscal years to Dec 2025 · latest quarter Mar 2026
Charts ten years each
Crescent Biopharma, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| NGNE Neurogene Inc. | $479.3M | — (loss-making) | — (loss-making) | — | n/m | −22.97% (below 0%: shrinking) | 100.00% | 0.00% | Compare |
| YDES YD Bio Limited | $477.5M | — | — | — | — | — | — | — | Compare |
| RGNX REGENXBIO Inc. | $472.7M | — (loss-making) | — (loss-making) | +405.73% (above 0%: growing) | n/m | −26.67% (below 0%: shrinking) | 99.04% | 27.09% | Compare |
| ARVN Arvinas, Inc. | $468.2M | 53.6× | — (loss-making) | +1,014.73% (above 0%: growing) | n/m | +49.79% (above 0%: growing) | 96.40% | 65.72% | Compare |
| CBIO Crescent Biopharma, Inc. | $463.6M | — (loss-making) | — (loss-making) | +1,038,900.00% (above 0%: growing) | n/m | −7.04% (below 0%: shrinking) | 100.00% | 0.00% | |
| ALLO Allogene Therapeutics, Inc. | $463.0M | — (loss-making) | — (loss-making) | +20,990.91% (above 0%: growing) | n/m | +17.73% (above 0%: growing) | 100.00% | (1,011.21%) | Compare |
| ALT Altimmune, Inc. | $459.1M | — (loss-making) | — (loss-making) | +520.00% (above 0%: growing) | n/m | −25.27% (below 0%: shrinking) | 100.00% | 0.00% | Compare |
| AUTL Autolus Therapeutics PLC Sponsored ADR | $457.8M | — (loss-making) | — (loss-making) | +118.37% (above 0%: growing) | n/m | +67.55% (above 0%: growing) | 55.20% | (95.95%) | Compare |
| OCS Oculis Holding AG | $456.8M | — (loss-making) | — (loss-making) | +23.96% (above 0%: growing) | n/m | −10.40% (below 0%: shrinking) | 100.00% | (7,603.42%) | Compare |
| Median of peers | $465.6M | — | — | +462.87% | — | −10.40% | 100.00% | 0.00% |
Crescent Biopharma, Inc. (CBIO) key facts
- Strength: Crescent Biopharma, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $10.8 million, up 108,340.0% from fiscal 2023.
- Crescent Biopharma, Inc. (CBIO) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
- As of October 16, 2026, CBIO traded at $11.84, a market capitalization of $463.6 million.
- Return on equity was −167.8% and debt-to-equity 0.00.
- Its Altman Z-score is −0.06 (distress zone) for fiscal 2025.