stockrowAxsome Therapeutics, Inc.
AXSM Healthcare Biotechnology
Axsome Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $638.5 million, up 65.5% from fiscal 2024.
- Revenue
- +51.9%
- EPS
- +73.9%
- Free cash flow
- −1,078.3%
- Total debt
- +4.04%
Quarter to September 2026, against a year earlier
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Axsome Therapeutics, Inc. (AXSM) Gross margin
Axsome Therapeutics, Inc.'s gross margin over the twelve months to 30 September 2026 was 93.3%, up 0.7 percentage points from fiscal 2025 (92.6%). Over the past ten years it has ranged from 0.00% (fiscal 2021) to 92.6% (fiscal 2025) — the current reading is the highest in ten years. That is above the Biotechnology industry median of 65.2% and above the Healthcare sector median of 53.9%.
Gross margin, annual
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Annual newest first
| Period | Gross margin | Change (points) |
|---|---|---|
| FY2025 | 92.6% | 1.19 |
| FY2024 | 91.4% | 1.00 |
| FY2023 | 90.4% | 0.76 |
| FY2022 | 89.6% | 89.61 |
| FY2021 | 0.00% | 0.00 |
| FY2020 | 0.00% | 0.00 |
| FY2019 | 0.00% | 0.00 |
| FY2018 | 0.00% | 0.00 |
| FY2017 | 0.00% | 0.00 |
| FY2016 | 0.00% | — |
Quarterly newest first
| Period | Gross margin | Change (points) |
|---|---|---|
| Sep 2026 | 93.1% | (0.65) |
| Jun 2026 | 93.8% | 1.49 |
| Mar 2026 | 92.3% | (1.41) |
| Dec 2025 | 93.7% | 0.68 |
| 24 more quarters | Free account |
Against its own ten years
Gross margin against peers
| Company | Gross margin |
|---|---|
| PRAX Praxis Precision Medicines, Inc. compare | 100.0% |
| IONS Ionis Pharmaceuticals, Inc. compare | 98.2% |
| LGND Ligand Pharmaceuticals Incorporated compare | 95.2% |
| AXSM Axsome Therapeutics, Inc. | 93.3% |
| RYTM Rhythm Pharmaceuticals, Inc. compare | 88.2% |
| MIRM Mirum Pharmaceuticals, Inc. compare | 81.7% |
| ORKA Oruka Therapeutics, Inc. compare | 0.00% |
| ABVX Abivax SA Sponsored ADR compare | 0.00% |
| BLTE Belite Bio, Inc. Sponsored ADR compare | — |
| Biotechnology industry median | 65.2% |
| Healthcare sector median | 53.9% |
| Market median | 45.1% |
What Gross margin is
Gross Margin tells an investor how much of each sale a company keeps after paying the direct costs of making or buying what it sells.
Gross Profit ÷ Revenue
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- Revenue
- Net income
- EPS (diluted)
- EBITDA
- Free cash flow
- Operating cash flow
- Operating margin
- Net margin
- Free cash flow margin
- P/E ratio
- P/S ratio
- P/B ratio
- Price to free cash flow
- EV/EBITDA
- EV/Sales
- EV/FCF
- Return on equity
- Return on assets
- Return on invested capital
- Debt to equity
- Current ratio
- Total debt
- Shares outstanding
- Book value per share
- Revenue growth
- Altman Z-score
- Beneish M-score
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