AnaptysBio, Inc.

ANAB Healthcare Biotechnology

AnaptysBio, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $234.6 million, up 157.0% from fiscal 2024. In the quarter to March 2026, revenue fell 7.98%, EPS fell 43.8% and free cash flow fell 141.6%, each against the same quarter a year earlier. Revenue growth for three consecutive years.

46.61 2.10 −4.31%
Market cap
$1.5B
P/E
0.0×
Fwd P/E
220×
Dividend yield
—
F-score
5/9
Altman Z
0.84
Beneish M
−2.34
Dividend safety
n/a

Insider Decisions trades per month

Total sells 9.75
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — — — — — —
Sell — 6 13 1 2 — — — — — — 1
Insider Ownership 2.69%

Capital & Financial Ratios $m

Market Cap 1,460.00
Revenue 232.39
Net Income (26.79)
Free Cash Flow 4.41
Net Debt (286.45)
Current Ratio 7.58 (at or above 1.5: strong)
Debt/Equity 0.00 (at or below 0.5: strong)
P/E ratio 0.00
Fwd P/E 220.00 (above 35: high)
P/S ratio 5.75
P/B ratio 104.91 (above 6: high)
Past 5Y EPS Growth —
This Y EPS Growth (643.59%) (below 0%: weak)
Next Y EPS Growth 225.44% (at or above 15%: strong)
Next Y revenue growth (54.95%) (below 0%: weak)
Next 5Y EPS Growth (3.89%) (below 0%: weak)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 25.19%
10-year low 10-year high
P/B against its own 10 years 94.63%
10-year low 10-year high
EV/Sales against its own 10 years 47.05%
10-year low 10-year high
EV/FCF against its own 10 years 87.49%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2017 Powerpack
predictions special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 391 385 312 286
Receivables 7 41 34 26
Inventory — — — —
Other — — — —
407 432 350 316
2023 2024 2025 Q'26
Payables 5 4 4 8
ST’ Debt — — — —
Other — — — —
37 45 39 42

Compound Annual Growth %

10y 5y 3y
Sales 29.58% 25.62% 183.58%
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value (1.28%) (37.71%) (47.83%)

Revenue $m

Mar Jun Sep Dec Year
’26 26 — — — —
’25 28 22 76 108 235
’24 7 11 30 43 91
’23 1 3 3 9 17
’22 1 1 1 7 10
’21 11 30 21 1 63
’20 15 — — 60 75
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (26) — — — —
’25 (11) (40) (27) 98 20
’24 (37) (21) (10) (67) (135)
’23 (25) (25) (36) (34) (121)
’22 (21) (24) (18) (11) (74)
’21 (23) 10 (7) (25) (46)
’20 (15) (20) (17) 38 (14)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (26) — — — —
’25 (11) (40) (27) 98 20
’24 (37) (21) (10) (67) (136)
’23 (25) (26) (37) (35) (122)
’22 (21) (24) (18) (11) (74)
’21 (24) 9 (7) (25) (47)
’20 (15) (20) (17) 37 (15)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (1.84) — — — —
’25 (1.28) (1.34) 0.52 1.58 (0.46)
’24 (1.64) (1.71) (1.14) (0.72) (5.12)
’23 (1.58) (1.50) (1.41) (1.59) (6.08)
’22 (1.31) (1.15) (1.18) (0.93) (4.57)
’21 (0.66) (0.02) (0.24) (1.18) (2.11)
’20 (0.30) (0.79) (0.87) 1.20 (0.73)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.1
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low — 10.11 36.17 6.67 8.04 11.81 12.13 8.91 8.34 8.14

Analyst estimates 2026–2028

Powerpack
High — 68.42 89.33 55.40 20.86 25.26 24.04 20.76 27.54 34.98
People
People Employees 49 60 78 89 94 102 96 117 136 104
Revenue/emp, $m 0.34 0.17 0.06 0.09 0.80 0.62 0.11 0.15 0.67 2.26
Income, $m
Income, $m Revenue 17 10 5 8 75 63 10 17 91 235
Gross margin, % 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00
EBT (4) (30) (62) (97) (20) (58) (129) (164) (145) (13)
EBT margin, % (25.53) (300.70) (1,236.96) (1,218.60) (26.57) (91.49) (1,251.09) (953.68) (159.10) (5.57)
Net income (4) (30) (62) (97) (20) (58) (129) (164) (145) (13)
Depreciation 0 0 (1) (1) 2 3 0 (8) (8) (2)
Per share, $
Per share, $ Revenue 6.33 0.51 0.20 0.30 2.75 2.30 0.37 0.64 3.22 8.16
Earnings (1.62) (1.52) (2.50) (3.60) (0.73) (2.11) (4.57) (6.08) (5.12) (0.46)
Cash flow (3.42) (0.98) (1.97) (2.57) (0.52) (1.67) (2.61) (4.49) (4.77) 0.68
Capex (0.02) (0.01) (0.04) (0.03) (0.02) (0.05) (0.01) (0.03) (0.01) 0.00
Free cash flow (3.44) (1.00) (2.01) (2.60) (0.54) (1.72) (2.63) (4.52) (4.78) 0.68
Book value 14.89 15.55 19.71 14.97 14.53 12.99 9.31 3.27 2.50 1.29
Shares, m 3 20 25 27 27 27 28 27 28 29
Valuation, ×
Valuation, × P/E 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
P/S 1.79 83.01 59.07 18.32 4.71 10.06 53.33 22.71 2.75 3.96
P/B 0.00 4.31 2.16 0.72 0.99 1.78 2.09 4.42 3.54 24.98
EV/Sales (0.45) 67.94 35.16 (4.92) 0.00 1.42 10.68 0.06 (1.45) 2.64
EV/FCF 0.83 (55.02) (12.60) 1.12 0.00 (1.90) (1.49) (0.01) 0.98 31.63
Cash, $m
Cash, $m Operating cash flow (9) (19) (49) (70) (14) (46) (74) (121) (135) 20
Capex 0 0 (1) (1) (1) (1) 0 (1) 0 0
Free cash flow (9) (20) (50) (70) (15) (47) (74) (122) (136) 20
Balance, $m
Balance, $m Working capital 53 239 412 348 377 538 421 369 386 312
Total debt 14 8 1 1 0 19 322 — — —
Net debt (37) (241) (427) (374) (394) (548) (441) (391) (385) (312)
Shareholders’ equity 39 308 486 405 397 356 262 88 71 37
Returns, %
Returns, % ROA (7.19) (15.36) (14.71) (20.62) (4.68) (10.91) (20.54) (30.79) (31.02) (3.12)
ROIC (102.47) (26.96) (70.34) (218.14) (484.87) 0.00 0.00 0.00 0.00 0.00
ROE 11.60 (22.33) (15.53) (21.84) (4.97) (15.35) (41.62) (93.44) (182.71) (24.49)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2025 · latest quarter Mar 2026

Charts ten years each

AnaptysBio, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
QURE uniQure N.V. $1.6B — (loss-making) — (loss-making) +11.00% (above 0%: growing) n/m +27.66% (above 0%: growing) 94.01% (893.73%) Compare
KRSA Korsana Biosciences, Inc. $1.5B — (loss-making) — (loss-making) −43.24% (below 0%: shrinking) n/m −184.69% (below 0%: shrinking) 100.00% 0.00% Compare
MAZE Maze Therapeutics, Inc. $1.5B — (loss-making) — — n/m +50.21% (above 0%: growing) 100.00% 0.00% Compare
ABSI Absci Corporation $1.5B — (loss-making) — (loss-making) −46.37% (below 0%: shrinking) n/m −71.74% (below 0%: shrinking) 100.00% (10,741.51%) Compare
IMCR Immunocore Holdings PLC Sponsored ADR $1.5B — (loss-making) 208× +18.34% (above 0%: growing) n/m −40.74% (below 0%: shrinking) 99.06% (2.58%) Compare
RARE Ultragenyx Pharmaceutical Inc. $1.5B — (loss-making) — (loss-making) +28.14% (above 0%: growing) n/m +12.50% (above 0%: growing) 84.11% (35.05%) Compare
ANAB AnaptysBio, Inc. $1.5B — (loss-making) 220× −7.98% (below 0%: shrinking) n/m −141.60% (below 0%: shrinking) 100.00% (135.53%)
RAPP Rapport Therapeutics, Inc. $1.4B — (loss-making) — — n/m −64.75% (below 0%: shrinking) 100.00% 0.00% Compare
AAPG Ascentage Pharma Group International - Unsponsored ADR $1.4B — — — — +17.74% (above 0%: growing) — — Compare
Median of peers $1.5B — — +11.00% — −14.12% 100.00% (2.58%)

All 614 Biotechnology stocks →

AnaptysBio, Inc. (ANAB) key facts

  • Strength: AnaptysBio, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $234.6 million, up 157.0% from fiscal 2024.
  • AnaptysBio, Inc. (ANAB) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, ANAB traded at $46.61, a market capitalization of $1.5 billion.
  • Return on equity was −24.5% and debt-to-equity 0.00.
  • Its Piotroski F-score is 5 out of 9 and its Altman Z-score is 0.84 (distress zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

AnaptysBio, Inc. (ANAB) Latest News

stockrow.com/ANAB · Data as of Mar 31, 2026 · For information only; not investment advice. · © 2026 stockrow.com