AC Immune

ACIU

Healthcare Biotechnology

AC Immune’s revenue for fiscal 2025 (year ended December 2025) was $4.3 million, down 86.1% from fiscal 2024.

Revenue
+152.3%
EPS
+36.0%
Free cash flow
+4.66%

Quarter to September 2026, against a year earlier

2.23 0.12 +5.69%
Market cap
$227.0M
P/E
n/m
Fwd P/E
n/m
Dividend yield
—
F-score
2/9
ROIC
0.00%
Net debt / EBITDA
1.4×
Dividend safety
n/a

Insider Decisions last twelve months

Net sold
$59.4K
Trades
2 sells · 0 buys
Ownership
7.05%

Capital & Financial Ratios $m

Size
Market Cap 227
Revenue ttm 7
Net income ttm (80)
Free cash flow ttm (84)
Net debt Q (91)
Valuation
P/E n/m
Forward P/E n/m
Price / sales 21.3 (above 10: high)
Forward P/S Powerpack
Price / FCF n/m
Price / book 4.5
Financial health
Current ratio Q 0.8 (below 1: weak)
Debt / equity Q n/m
Interest coverage Q (166.2)
Growth
Revenue growth Q +152.3% (above 0%: growing)
Operating income growth Q +48.7% (above 0%: growing)
EPS, this year +45.4% (at or above 15%: strong)
EPS, next year A +169.3% (at or above 15%: strong)
Revenue, next year A +427.7% (at or above 10%: strong)
EPS, past 5 yrs —
EPS, next 5 yrs A +7.6%

Green and red mark values outside typical ranges; (Q) is the latest quarter, (A) analysts’ estimates; n/m is not meaningful, as a P/E on a loss. How we judge →

Valuation vs history

P/S against its own 10 years 35.20%
10-year low 10-year high
P/B against its own 10 years 79.53%
10-year low 10-year high
EV/Sales against its own 10 years 39.44%
10-year low 10-year high

Dividends

Yield
—
Annual rate
—
Payout ratio
—

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 115 188 110 91
Receivables 17 1 1 5
Inventory — — — —
Other 0 1 0 0
139 195 117 102
2023 2024 2025 Q'26
Payables 2 3 2 1
ST’ Debt — — — —
Other — — — —
15 115 114 120

Compound Annual Growth %

10y 5y 3y
Sales — (47.84%) 1.51%
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value (3.06%) (25.10%) (32.62%)

Earnings Trends EPS, adjusted, against the consensus

EPS $

Mar Jun Sep Dec Year
’26 (0.19) — (0.16) — —
’25 (0.21) (0.25) (0.20) (0.18) (0.84)
’24 (0.21) (0.25) 0.06 (0.18) (0.58)
’23 (0.23) (0.22) (0.20) (0.06) (0.71)
’22 (0.25) (0.24) (0.17) (0.24) (0.89)
’21 (0.25) (0.29) (0.24) (0.28) (1.06)
’20 (0.11) (0.23) (0.28) (0.30) (0.92)
Fiscal quarters ending in the months shown.

Revenue $m

Mar Jun Sep Dec Year
’26 1 — 4 — —
’25 1 2 1 0 4
’24 — 1 29 1 31
’23 — — — — 16
’22 — — 4 0 4
’20 13 1 1 1 16
’19 75 2 34 1 112
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 — (20) — — —
’25 (21) (21) (24) (18) (84)
’24 1 81 (13) 6 75
’23 (18) (16) (16) (17) (67)
’22 (25) (19) (14) (19) (77)
’21 (19) (17) (16) (20) (72)
’20 (10) (15) (18) (20) (63)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 — (20) — — —
’25 (21) (21) (24) (18) (85)
’24 1 81 (13) 5 74
’23 (18) (16) (16) (17) (68)
’22 (26) (20) (14) (19) (78)
’21 (20) (18) (16) (21) (75)
’20 (10) (16) (18) (21) (65)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Ten-year view Analyst estimates Powerpack
Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 TTM Sep ’26 Trend 10 yrs 2026e 2027e 2028e Next 3/yr
Income, $m
Income, $m Revenue 24 21 7 112 16 — 4 16 31 4 7 (17.2%) 23 109 131 +212.3%
Gross margin, % 100.00 100.00 100.00 100.00 100.00 0.00 100.00 100.00 100.00 100.00 100.00 0.0 pt
EBT (7) (27) (52) 46 (66) (80) (74) (60) (58) (85) (68) +31.6%
EBT margin, % (30.57) (130.39) (708.25) 40.93 (401.28) 0.00 (1,797.71) (366.35) (186.43) (1,971.65) (962.17) (1,941.1) pt
Net income (7) (27) (52) 46 (66) (80) (74) (60) (58) (85) (80) +31.6%
Per share, $
Per share, $ Revenue 0.47 0.36 0.12 1.58 0.23 0.00 0.05 0.19 0.31 0.04 0.10 (23.4%)
Earnings (0.14) (0.47) (0.84) 0.64 (0.92) (1.06) (0.89) (0.71) (0.58) (0.84) (0.73) +22.0%
Cash flow (0.11) (0.39) (0.73) 0.79 (0.88) (0.96) (0.92) (0.79) 0.75 (0.83) 0.00 +24.6%
Capex (0.02) (0.03) (0.03) (0.03) (0.02) (0.04) (0.02) (0.01) (0.01) (0.01) 0.00 (5.8%)
Free cash flow (0.13) (0.43) (0.76) 0.76 (0.91) (1.00) (0.94) (0.80) 0.74 (0.84) 0.00 +22.8%
Book value 2.89 2.08 2.94 3.88 3.20 3.39 2.12 2.11 1.28 0.54 0.49 (17.0%)
Shares, m 50 57 62 71 72 75 84 85 100 101 92 +8.1%
Valuation, ×
Valuation, × P/E 37.17 0.00 0.00 12.72 0.00 — 0.00 0.00 0.00 0.00 0.00 5.5
P/S 0.00 37.02 79.45 5.38 22.59 — 28.75 61.84 8.66 73.36 21.29 35.2
P/B 4.30 6.42 3.22 2.19 1.62 — 1.04 2.22 2.11 5.84 4.52 3.2
EV/Sales 0.00 30.90 53.60 2.81 8.09 — 9.13 44.36 2.69 48.34 9.06 22.2
EV/FCF 12.52 (26.19) (8.39) 5.84 (2.04) — (0.75) (4.18) 1.13 (2.46) (0.76) (2.7)
Cash, $m
Cash, $m Operating cash flow (6) (22) (45) 56 (63) (72) (77) (67) 75 (84) (82) +34.7%
Capex (1) (2) (2) (2) (2) (3) (1) (1) (1) (1) (1) +1.8%
Free cash flow (7) (24) (47) 54 (65) (75) (78) (68) 74 (85) (84) +32.7%
Balance, $m
Balance, $m Working capital 147 122 184 277 232 200 122 124 81 2 (19) (36.6%)
Net debt (155) (126) (190) (290) (241) (217) (128) (115) (188) (110) (91) (3.7%)
Shareholders’ equity 145 119 182 274 230 254 177 179 128 54 33 (10.3%)
Returns, %
Returns, % ROA (5.96) (18.34) (31.09) 18.22 (23.76) (29.54) (30.84) (30.32) (24.83) (37.92) (33.75) (32.0) pt
ROIC 0.00 0.00 0.00 0.00 0.00 (146.26) (95.42) (58.19) 0.00 0.00 0.00 0.0 pt
ROE (6.59) (20.39) (34.69) 20.07 (26.21) (33.03) (34.41) (33.94) (37.74) (93.59) (122.01) (87.0) pt
People
People Employees 67 86 104 132 149 143 156 161 172 122 — +6.9%
Revenue/emp, $m 0.35 0.24 0.07 0.85 0.11 0.00 0.03 0.10 0.18 0.04 — (22.5%)
Negative figures in brackets.
estimates

All 10 years →

Fiscal years to Dec 2025 · latest quarter Sep 2026 · fundamentals updated 6 Nov 2026

AC Immune vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
CABA Cabaletta Bio, Inc. $280.4M — (loss-making) — — n/m −35.72% (below 0%: shrinking) 0.00% 0.00% Compare
ABEO Abeona Therapeutics Inc. $238.5M — (loss-making) — (loss-making) +225.14% (above 0%: growing) n/m +17.11% (above 0%: growing) 63.30% (119.97%) Compare
IMRX Immuneering Corporation $238.3M — (loss-making) — (loss-making) −99.74% (below 0%: shrinking) n/m −40.19% (below 0%: shrinking) 0.00% 0.00% Compare
VNDA Vanda Pharmaceuticals Inc. $231.0M — (loss-making) — (loss-making) +24.10% (above 0%: growing) n/m +9.57% (above 0%: growing) 94.05% (33.69%) Compare
ACIU AC Immune $227.0M — (loss-making) — (loss-making) +152.31% (above 0%: growing) n/m +4.66% (above 0%: growing) 100.00% (302.13%)
FATE Fate Therapeutics, Inc. $223.1M — (loss-making) — (loss-making) +9.18% (above 0%: growing) n/m +8.96% (above 0%: growing) 100.00% (1,495.39%) Compare
GLSI Greenwich LifeSciences, Inc. $222.7M — (loss-making) — — n/m +13.14% (above 0%: growing) 0.00% 0.00% Compare
KRRO Korro Bio, Inc. $202.5M — (loss-making) — (loss-making) −86.28% (below 0%: shrinking) n/m +12.07% (above 0%: growing) 100.00% 0.00% Compare
SLGL Sol-Gel Technologies Ltd. $199.8M — (loss-making) — (loss-making) −96.58% (below 0%: shrinking) n/m −8.76% (below 0%: shrinking) 100.00% (704.23%) Compare
Median of peers $227.0M — — −38.55% — +9.27% 78.68% (16.84%)

All 621 Biotechnology stocks →

AC Immune (ACIU) Latest News

4 Nov

30 Sep

Impact 3 · · Zacks

18 Mar

Impact 3 · · Zacks

13 Mar

Impact 3 · · Associated Press Finance

24 Feb

13 Jan

Impact 3 · · Simply Wall St.

11 Dec

Impact 4 · · biopharmadive.com
Impact 3 · · Associated Press Finance
stockrow.com/ACIU · Data as of Nov 6, 2026 · For information only; not investment advice. · © 2026 stockrow.com