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AC Immune (ACIU) vs Vanda Pharmaceuticals Inc. (VNDA)

AC Immune and Vanda Pharmaceuticals Inc. are both Biotechnology companies. AC Immune and Vanda Pharmaceuticals Inc. are of similar size ($231.0M and $227.0M). Vanda Pharmaceuticals Inc. grew revenue faster over the last twelve months: 8.11% against −78.6%. Vanda Pharmaceuticals Inc. has the higher net margin (−119.9% vs −962.2%) and the lower return on invested capital (−180.2% vs 0.00%). Across the 18 metrics below, AC Immune leads on 9 and Vanda Pharmaceuticals Inc. on 9.

Valuation

Metric ACIU VNDA Biotechnology median
P/E n/m n/m 10.60
P/S 21.29 1.01 9.40
P/B 4.52 1.16 2.13
Price to free cash flow n/m n/m 25.18
EV/EBITDA n/m n/m 0.66
EV/Sales 9.06 0.40 9.02
Earnings yield (32.74%) (121.02%) (32.88%)
Free cash flow yield (55.75%) (64.93%) (23.13%)

Profitability

Metric ACIU VNDA Biotechnology median
Gross margin 100.00% 93.59% 68.51%
Operating margin (986.55%) (77.59%) 0.00%
Net margin (962.17%) (119.87%) 0.00%
Free cash flow margin 0.00% (65.41%) 0.00%
Return on equity (122.01%) (82.55%) (51.96%)
Return on assets (33.75%) (55.89%) (46.06%)
Return on invested capital 0.00% (180.19%) 0.00%

Growth

Metric ACIU VNDA Biotechnology median
Revenue growth (TTM) (78.60%) 8.11% 6.76%
EPS growth (last fiscal year) (44.83%) (1,033.33%) 29.88%
Revenue growth, 5-year CAGR (47.84%) (2.73%) 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric ACIU VNDA Biotechnology median
Debt to equity 0.00 0.01 0.00
Current ratio 0.85 1.54 4.97
Net debt to EBITDA 1.37 1.84 1.01

Dividend

Metric ACIU VNDA Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric ACIU VNDA Biotechnology median
Market cap 226.96m 230.99m 161.82m

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