Sunday 18 October 2026
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AC Immune
ACIU Healthcare Biotechnology
AC Immune’s revenue for fiscal 2025 (year ended December 2025) was $4.3 million, down 86.1% from fiscal 2024. In the quarter to June 2026, revenue grew 29.7%, EPS grew 9.52% and free cash flow grew 4.66%, each against the same quarter a year earlier.
2.39
0.06
−2.45%
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Target Price Range
Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Trend | 2026e | 2027e | 2028e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Price, $ | |||||||||||||||
| Price, $ | Low | 10.36 | 6.03 | 7.16 | 3.25 | 4.07 | 4.68 | 1.68 | 1.78 | 2.25 | 1.43 |
Analyst estimates 2026–2028 Powerpack |
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| High | 19.97 | 14.06 | 17.40 | 12.15 | 13.00 | 12.61 | 5.21 | 5.14 | 5.04 | 4.00 | |||||
| People | |||||||||||||||
| People | Employees | 67 | 86 | 104 | 132 | 149 | 143 | 156 | 161 | 172 | 122 | ||||
| Revenue/emp, $m | 0.35 | 0.24 | 0.07 | 0.85 | 0.11 | 0.00 | 0.03 | 0.10 | 0.18 | 0.04 | |||||
| Income, $m | |||||||||||||||
| Income, $m | Revenue | 24 | 21 | 7 | 112 | 16 | — | 4 | 16 | 31 | 4 | ||||
| Gross margin, % | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 0.00 | 100.00 | 100.00 | 100.00 | 100.00 | |||||
| EBT | (7) | (27) | (52) | 46 | (66) | (80) | (74) | (60) | (58) | (85) | |||||
| EBT margin, % | (30.57) | (130.39) | (708.25) | 40.93 | (401.28) | 0.00 | (1,797.71) | (366.35) | (186.43) | (1,971.65) | |||||
| Net income | (7) | (27) | (52) | 46 | (66) | (80) | (74) | (60) | (58) | (85) | |||||
| Depreciation | 0 | 1 | 1 | 1 | 2 | 3 | 2 | 2 | 2 | 3 | |||||
| Per share, $ | |||||||||||||||
| Per share, $ | Revenue | 0.47 | 0.36 | 0.12 | 1.58 | 0.23 | 0.00 | 0.05 | 0.19 | 0.31 | 0.04 | ||||
| Earnings | (0.14) | (0.47) | (0.84) | 0.64 | (0.92) | (1.06) | (0.89) | (0.71) | (0.58) | (0.84) | |||||
| Cash flow | (0.11) | (0.39) | (0.73) | 0.79 | (0.88) | (0.96) | (0.92) | (0.79) | 0.75 | (0.83) | |||||
| Capex | (0.02) | (0.03) | (0.03) | (0.03) | (0.02) | (0.04) | (0.02) | (0.01) | (0.01) | (0.01) | |||||
| Free cash flow | (0.13) | (0.43) | (0.76) | 0.76 | (0.91) | (1.00) | (0.94) | (0.80) | 0.74 | (0.84) | |||||
| Book value | 2.89 | 2.08 | 2.94 | 3.88 | 3.20 | 3.39 | 2.12 | 2.11 | 1.28 | 0.54 | |||||
| Shares, m | 50 | 57 | 62 | 71 | 72 | 75 | 84 | 85 | 100 | 101 | |||||
| Valuation, × | |||||||||||||||
| Valuation, × | P/E | 37.17 | 0.00 | 0.00 | 12.72 | 0.00 | — | 0.00 | 0.00 | 0.00 | 0.00 | ||||
| P/S | 0.00 | 37.02 | 79.45 | 5.38 | 22.59 | — | 28.75 | 61.84 | 8.66 | 73.36 | |||||
| P/B | 4.30 | 6.42 | 3.22 | 2.19 | 1.62 | — | 1.04 | 2.22 | 2.11 | 5.84 | |||||
| EV/Sales | 0.00 | 30.90 | 53.60 | 2.81 | 8.09 | — | 9.13 | 44.36 | 2.69 | 48.34 | |||||
| EV/FCF | 12.52 | (26.19) | (8.39) | 5.84 | (2.04) | — | (0.75) | (4.18) | 1.13 | (2.46) | |||||
| Cash, $m | |||||||||||||||
| Cash, $m | Operating cash flow | (6) | (22) | (45) | 56 | (63) | (72) | (77) | (67) | 75 | (84) | ||||
| Capex | (1) | (2) | (2) | (2) | (2) | (3) | (1) | (1) | (1) | (1) | |||||
| Free cash flow | (7) | (24) | (47) | 54 | (65) | (75) | (78) | (68) | 74 | (85) | |||||
| Balance, $m | |||||||||||||||
| Balance, $m | Working capital | 147 | 122 | 184 | 277 | 232 | 200 | 122 | 124 | 81 | 2 | ||||
| Total debt | — | 0 | 1 | 1 | 3 | 3 | 3 | — | — | — | |||||
| Net debt | (155) | (126) | (190) | (290) | (241) | (217) | (128) | (115) | (188) | (110) | |||||
| Shareholders’ equity | 145 | 119 | 182 | 274 | 230 | 254 | 177 | 179 | 128 | 54 | |||||
| Returns, % | |||||||||||||||
| Returns, % | ROA | (5.96) | (18.34) | (31.09) | 18.22 | (23.76) | (29.54) | (30.84) | (30.32) | (24.83) | (37.92) | ||||
| ROIC | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | (146.26) | (95.42) | (58.19) | 0.00 | 0.00 | |||||
| ROE | (6.59) | (20.39) | (34.69) | 20.07 | (26.21) | (33.03) | (34.41) | (33.94) | (37.74) | (93.59) | |||||
Negative figures in brackets.
Fiscal years to Dec 2025 · latest quarter Mar 2026
Charts ten years each
AC Immune vs peers in Biotechnology (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| CABA Cabaletta Bio, Inc. | $262.8M | — (loss-making) | — | — | n/m | −35.72% (below 0%: shrinking) | 0.00% | 0.00% | Compare |
| XFOR X4 Pharmaceuticals, Inc. | $261.8M | — (loss-making) | — (loss-making) | +346.33% (above 0%: growing) | n/m | +13.76% (above 0%: growing) | 81.64% | (186.13%) | Compare |
| RCKT Rocket Pharmaceuticals, Inc. | $259.1M | — (loss-making) | — | — | n/m | +19.16% (above 0%: growing) | 0.00% | 0.00% | Compare |
| VNDA Vanda Pharmaceuticals Inc. | $256.4M | — (loss-making) | — (loss-making) | −3.92% (below 0%: shrinking) | n/m | −101.02% (below 0%: shrinking) | 92.95% | (126.28%) | Compare |
| IKT Inhibikase Therapeutics, Inc. | $255.4M | — (loss-making) | — (loss-making) | −100.00% (below 0%: shrinking) | n/m | −123.23% (below 0%: shrinking) | 0.00% | 0.00% | Compare |
| LCTX Lineage Cell Therapeutics, Inc. | $250.5M | — (loss-making) | — (loss-making) | −61.34% (below 0%: shrinking) | n/m | −32.40% (below 0%: shrinking) | 100.00% | (834.71%) | Compare |
| ACIU AC Immune | $249.4M | — (loss-making) | — (loss-making) | +29.66% (above 0%: growing) | n/m | +4.66% (above 0%: growing) | 100.00% | (1,321.50%) | |
| BBOT BridgeBio Oncology Therapeutics, Inc | $236.5M | — (loss-making) | — | — | n/m | −88.78% (below 0%: shrinking) | — | 0.00% | Compare |
| SABS SAB Biotherapeutics, Inc. | $235.7M | — (loss-making) | 19.9× | −90.95% (below 0%: shrinking) | n/m | −59.75% (below 0%: shrinking) | 100.00% | 0.00% | Compare |
| Median of peers | $255.9M | — | — | −61.34% | — | −47.74% | 81.64% | 0.00% |
AC Immune (ACIU) key facts
- Concern: AC Immune’s revenue for fiscal 2025 (year ended December 2025) was $4.3 million, down 86.1% from fiscal 2024.
- AC Immune (ACIU) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
- As of October 16, 2026, ACIU traded at $2.39, a market capitalization of $249.4 million.
- Return on equity was −93.6% and debt-to-equity 0.00.
- Its Piotroski F-score is 2 out of 9 and its Altman Z-score is −3.99 (distress zone) for fiscal 2025.