AC Immune

ACIU Healthcare Biotechnology

AC Immune’s revenue for fiscal 2025 (year ended December 2025) was $4.3 million, down 86.1% from fiscal 2024. In the quarter to June 2026, revenue grew 29.7%, EPS grew 9.52% and free cash flow grew 4.66%, each against the same quarter a year earlier.

2.39 0.06 −2.45%
Market cap
$249.4M
P/E
0.0×
Fwd P/E
−5.3×
Dividend yield
—
F-score
2/9
Altman Z
−3.99
Beneish M
1.01
Dividend safety
n/a

Insider Decisions trades per month

Total sells 0.06
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — — — — — —
Sell — — — — — 1 1 — — — — —
Insider Ownership 36.60%

Capital & Financial Ratios $m

Market Cap 249.35
Revenue 4.64
Net Income (80.22)
Free Cash Flow (83.67)
Net Debt (95.35)
Current Ratio 0.93 (below 1: weak)
Debt/Equity 0.00 (at or below 0.5: strong)
P/E ratio 0.00
Fwd P/E (5.31) (negative: loss-making)
P/S ratio 50.83 (above 10: high)
P/B ratio 5.30
Past 5Y EPS Growth —
This Y EPS Growth 39.33% (at or above 15%: strong)
Next Y EPS Growth 147.39% (at or above 15%: strong)
Next Y revenue growth 421.31% (at or above 10%: strong)
Next 5Y EPS Growth 7.55%

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 78.52%
10-year low 10-year high
P/B against its own 10 years 86.84%
10-year low 10-year high
EV/Sales against its own 10 years 79.64%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2017 Powerpack
special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 115 188 110 95
Receivables 17 1 1 17
Inventory — — — —
Other 0 1 0 0
139 195 117 118
2023 2024 2025 Q'26
Payables 2 3 2 2
ST’ Debt — — — —
Other — — — —
15 115 114 127

Compound Annual Growth %

10y 5y 3y
Sales — (47.84%) 1.51%
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value (3.06%) (25.10%) (32.62%)

Revenue $m

Mar Jun Sep Dec Year
’26 1 — — — —
’25 1 2 1 0 4
’24 — 1 29 1 31
’23 — — — — 16
’22 — — 4 0 4
’20 13 1 1 1 16
’19 75 2 34 1 112
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 — (20) — — —
’25 (21) (21) (24) (18) (84)
’24 1 81 (13) 6 75
’23 (18) (16) (16) (17) (67)
’22 (25) (19) (14) (19) (77)
’21 (19) (17) (16) (20) (72)
’20 (10) (15) (18) (20) (63)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 — (20) — — —
’25 (21) (21) (24) (18) (85)
’24 1 81 (13) 5 74
’23 (18) (16) (16) (17) (68)
’22 (26) (20) (14) (19) (78)
’21 (20) (18) (16) (21) (75)
’20 (10) (16) (18) (21) (65)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.19) — — — —
’25 (0.21) (0.25) (0.20) (0.18) (0.84)
’24 (0.21) (0.25) 0.06 (0.18) (0.58)
’23 (0.23) (0.22) (0.20) (0.06) (0.71)
’22 (0.25) (0.24) (0.17) (0.24) (0.89)
’21 (0.25) (0.29) (0.24) (0.28) (1.06)
’20 (0.11) (0.23) (0.28) (0.30) (0.92)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low 10.36 6.03 7.16 3.25 4.07 4.68 1.68 1.78 2.25 1.43

Analyst estimates 2026–2028

Powerpack
High 19.97 14.06 17.40 12.15 13.00 12.61 5.21 5.14 5.04 4.00
People
People Employees 67 86 104 132 149 143 156 161 172 122
Revenue/emp, $m 0.35 0.24 0.07 0.85 0.11 0.00 0.03 0.10 0.18 0.04
Income, $m
Income, $m Revenue 24 21 7 112 16 — 4 16 31 4
Gross margin, % 100.00 100.00 100.00 100.00 100.00 0.00 100.00 100.00 100.00 100.00
EBT (7) (27) (52) 46 (66) (80) (74) (60) (58) (85)
EBT margin, % (30.57) (130.39) (708.25) 40.93 (401.28) 0.00 (1,797.71) (366.35) (186.43) (1,971.65)
Net income (7) (27) (52) 46 (66) (80) (74) (60) (58) (85)
Depreciation 0 1 1 1 2 3 2 2 2 3
Per share, $
Per share, $ Revenue 0.47 0.36 0.12 1.58 0.23 0.00 0.05 0.19 0.31 0.04
Earnings (0.14) (0.47) (0.84) 0.64 (0.92) (1.06) (0.89) (0.71) (0.58) (0.84)
Cash flow (0.11) (0.39) (0.73) 0.79 (0.88) (0.96) (0.92) (0.79) 0.75 (0.83)
Capex (0.02) (0.03) (0.03) (0.03) (0.02) (0.04) (0.02) (0.01) (0.01) (0.01)
Free cash flow (0.13) (0.43) (0.76) 0.76 (0.91) (1.00) (0.94) (0.80) 0.74 (0.84)
Book value 2.89 2.08 2.94 3.88 3.20 3.39 2.12 2.11 1.28 0.54
Shares, m 50 57 62 71 72 75 84 85 100 101
Valuation, ×
Valuation, × P/E 37.17 0.00 0.00 12.72 0.00 — 0.00 0.00 0.00 0.00
P/S 0.00 37.02 79.45 5.38 22.59 — 28.75 61.84 8.66 73.36
P/B 4.30 6.42 3.22 2.19 1.62 — 1.04 2.22 2.11 5.84
EV/Sales 0.00 30.90 53.60 2.81 8.09 — 9.13 44.36 2.69 48.34
EV/FCF 12.52 (26.19) (8.39) 5.84 (2.04) — (0.75) (4.18) 1.13 (2.46)
Cash, $m
Cash, $m Operating cash flow (6) (22) (45) 56 (63) (72) (77) (67) 75 (84)
Capex (1) (2) (2) (2) (2) (3) (1) (1) (1) (1)
Free cash flow (7) (24) (47) 54 (65) (75) (78) (68) 74 (85)
Balance, $m
Balance, $m Working capital 147 122 184 277 232 200 122 124 81 2
Total debt — 0 1 1 3 3 3 — — —
Net debt (155) (126) (190) (290) (241) (217) (128) (115) (188) (110)
Shareholders’ equity 145 119 182 274 230 254 177 179 128 54
Returns, %
Returns, % ROA (5.96) (18.34) (31.09) 18.22 (23.76) (29.54) (30.84) (30.32) (24.83) (37.92)
ROIC 0.00 0.00 0.00 0.00 0.00 (146.26) (95.42) (58.19) 0.00 0.00
ROE (6.59) (20.39) (34.69) 20.07 (26.21) (33.03) (34.41) (33.94) (37.74) (93.59)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2025 · latest quarter Mar 2026

Charts ten years each

AC Immune vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
CABA Cabaletta Bio, Inc. $262.8M — (loss-making) — — n/m −35.72% (below 0%: shrinking) 0.00% 0.00% Compare
XFOR X4 Pharmaceuticals, Inc. $261.8M — (loss-making) — (loss-making) +346.33% (above 0%: growing) n/m +13.76% (above 0%: growing) 81.64% (186.13%) Compare
RCKT Rocket Pharmaceuticals, Inc. $259.1M — (loss-making) — — n/m +19.16% (above 0%: growing) 0.00% 0.00% Compare
VNDA Vanda Pharmaceuticals Inc. $256.4M — (loss-making) — (loss-making) −3.92% (below 0%: shrinking) n/m −101.02% (below 0%: shrinking) 92.95% (126.28%) Compare
IKT Inhibikase Therapeutics, Inc. $255.4M — (loss-making) — (loss-making) −100.00% (below 0%: shrinking) n/m −123.23% (below 0%: shrinking) 0.00% 0.00% Compare
LCTX Lineage Cell Therapeutics, Inc. $250.5M — (loss-making) — (loss-making) −61.34% (below 0%: shrinking) n/m −32.40% (below 0%: shrinking) 100.00% (834.71%) Compare
ACIU AC Immune $249.4M — (loss-making) — (loss-making) +29.66% (above 0%: growing) n/m +4.66% (above 0%: growing) 100.00% (1,321.50%)
BBOT BridgeBio Oncology Therapeutics, Inc $236.5M — (loss-making) — — n/m −88.78% (below 0%: shrinking) — 0.00% Compare
SABS SAB Biotherapeutics, Inc. $235.7M — (loss-making) 19.9× −90.95% (below 0%: shrinking) n/m −59.75% (below 0%: shrinking) 100.00% 0.00% Compare
Median of peers $255.9M — — −61.34% — −47.74% 81.64% 0.00%

All 614 Biotechnology stocks →

AC Immune (ACIU) key facts

  • Concern: AC Immune’s revenue for fiscal 2025 (year ended December 2025) was $4.3 million, down 86.1% from fiscal 2024.
  • AC Immune (ACIU) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, ACIU traded at $2.39, a market capitalization of $249.4 million.
  • Return on equity was −93.6% and debt-to-equity 0.00.
  • Its Piotroski F-score is 2 out of 9 and its Altman Z-score is −3.99 (distress zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

AC Immune (ACIU) Latest News

18 Mar

13 Jan

stockrow.com/ACIU · Data as of Mar 31, 2026 · For information only; not investment advice. · © 2026 stockrow.com