Krystal Biotech, Inc. (KRYS) vs Kymera Therapeutics, Inc. (KYMR)

Krystal Biotech, Inc. and Kymera Therapeutics, Inc. are both Biotechnology companies. Krystal Biotech, Inc. and Kymera Therapeutics, Inc. are of similar size ($10.2B and $9.7B). Kymera Therapeutics, Inc. has negative trailing earnings, so its P/E is not meaningful; Krystal Biotech, Inc. trades at 41.9×. Kymera Therapeutics, Inc. grew revenue faster over the last twelve months: 134.8% against 22.6%. Krystal Biotech, Inc. has the higher net margin (54.8% vs −285.3%) and the higher return on invested capital (24.1% vs −26.7%). Across the 17 metrics below, Krystal Biotech, Inc. leads on 13 and Kymera Therapeutics, Inc. on 4.

Valuation

Metric KRYS KYMR Biotechnology median
P/E 41.86 n/m 7.88
P/S 23.21 105.17 11.47
P/B 7.52 7.32 2.52
Price to free cash flow 39.65 n/m 21.16
EV/EBITDA 45.87 n/m 0.74
EV/Sales 21.29 98.60 10.73
Earnings yield 2.39% (2.88%) (28.84%)
Free cash flow yield 2.52% (2.15%) (23.03%)

Profitability

Metric KRYS KYMR Biotechnology median
Gross margin 94.64% 100.00% 65.16%
Operating margin 44.89% (333.50%) 0.00%
Net margin 54.82% (285.33%) 0.00%
Free cash flow margin 58.52% (226.62%) 0.00%
Return on equity 20.12% (24.15%) (57.72%)
Return on assets 18.30% (21.58%) (49.22%)
Return on invested capital 24.07% (26.72%) 0.00%

Growth

Metric KRYS KYMR Biotechnology median
Revenue growth (TTM) 22.63% 134.84% 5.64%
EPS growth (last fiscal year) 128.00% (23.83%) —
Revenue growth, 5-year CAGR — 2.87% 8.40%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric KRYS KYMR Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 8.32 10.34 4.73
Net debt to EBITDA (4.93) 2.42 0.96

Dividend

Metric KRYS KYMR Biotechnology median
Dividend yield — — 2.10%
Payout ratio 0.00 0.00 0.00

Size

Metric KRYS KYMR Biotechnology median
Market cap 10.21b 9.69b 162.10m

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