Caris Life Sciences,�Inc. (CAI) vs Krystal Biotech, Inc. (KRYS)

Caris Life Sciences,�Inc. and Krystal Biotech, Inc. are both Biotechnology companies. Krystal Biotech, Inc. is the larger, with a market value of $10.2B against $9.1B — 1.1× the size. Krystal Biotech, Inc. trades at the lower P/E: 41.9× against 85.1×. Caris Life Sciences,�Inc. grew revenue faster over the last twelve months: 96.4% against 22.6%. Krystal Biotech, Inc. has the higher net margin (54.8% vs 8.15%) and the lower return on invested capital (24.1% vs 50.0%). Across the 20 metrics below, Krystal Biotech, Inc. leads on 15 and Caris Life Sciences,�Inc. on 5.

Valuation

Metric CAI KRYS Biotechnology median
P/E 85.08 41.86 7.88
P/S 9.14 23.21 11.47
P/B 15.29 7.52 2.52
Price to free cash flow 72.98 39.65 21.16
EV/EBITDA 48.03 45.87 0.74
EV/Sales 8.74 21.29 10.73
Earnings yield 1.18% 2.39% (28.84%)
Free cash flow yield 1.37% 2.52% (23.03%)

Profitability

Metric CAI KRYS Biotechnology median
Gross margin 69.66% 94.64% 65.16%
Operating margin 15.49% 44.89% 0.00%
Net margin 8.15% 54.82% 0.00%
Free cash flow margin 12.53% 58.52% 0.00%
Return on equity 15.45% 20.12% (57.72%)
Return on assets 7.39% 18.30% (49.22%)
Return on invested capital 49.95% 24.07% 0.00%

Growth

Metric CAI KRYS Biotechnology median
Revenue growth (TTM) 96.36% 22.63% 5.64%
EPS growth (last fiscal year) 59.45% 128.00% —
Revenue growth, 5-year CAGR — — 8.40%
Net income growth, 5-year CAGR — 0.00% 0.00%

Health

Metric CAI KRYS Biotechnology median
Debt to equity 0.66 0.00 0.00
Current ratio 5.53 8.32 4.73
Net debt to EBITDA (5.23) (4.93) 0.96

Dividend

Metric CAI KRYS Biotechnology median
Dividend yield — — 2.10%
Payout ratio — 0.00 0.00

Size

Metric CAI KRYS Biotechnology median
Market cap 9.12b 10.21b 162.10m

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