Ionis Pharmaceuticals, Inc. (IONS) vs Spyre Therapeutics, Inc. (SYRE)
- Ionis Pharmaceuticals, Inc. IONS 42.94 −2.67%
- Spyre Therapeutics, Inc. SYRE 79.90 −0.25%
Ionis Pharmaceuticals, Inc. and Spyre Therapeutics, Inc. are both Biotechnology companies. Ionis Pharmaceuticals, Inc. and Spyre Therapeutics, Inc. are of similar size ($7.4B and $7.3B). Ionis Pharmaceuticals, Inc. grew revenue faster over the last twelve months: −7.41% against −81.8%. Spyre Therapeutics, Inc. has the higher net margin (0.00% vs −64.7%) and the higher return on invested capital (0.00% vs 0.00%). Across the 17 metrics below, Spyre Therapeutics, Inc. leads on 11 and Ionis Pharmaceuticals, Inc. on 6.
Valuation
Profitability
| Metric | IONS | SYRE | Biotechnology median |
|---|---|---|---|
| Gross margin | 98.17% | 100.00% | 65.16% |
| Operating margin | (68.00%) | 0.00% | 0.00% |
| Net margin | (64.66%) | 0.00% | 0.00% |
| Free cash flow margin | (64.93%) | 0.00% | 0.00% |
| Return on equity | (105.50%) | (28.52%) | (56.36%) |
| Return on assets | (18.90%) | (20.90%) | (48.04%) |
| Return on invested capital | 0.00% | 0.00% | 0.00% |
Growth
Health
Dividend
Size
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