United Therapeutics Corporation

UTHR Healthcare Drug Manufacturers Specialty & Generic

United Therapeutics Corporation’s revenue for fiscal 2025 (year ended December 2025) was $3.2 billion, up 10.6% from fiscal 2024.

Revenue
+4.13%
EPS
−21.7%
Free cash flow
−63.7%

Quarter to September 2026, against a year earlier

564.88 43.61 −7.17%
Market cap
$24.3B
P/E
19.7×
Fwd P/E
22.5×
Dividend yield
—
F-score
8/9
Altman Z
19.55
Beneish M
−2.26
Dividend safety
n/a

Revenue by products and services Fiscal 2025

  • Tyvaso DPI
  • Nebulized Tyvaso
  • Remodulin
  • Orenitram
  • Unituxin
  • Adcirca
  • Other

Every year since 2011 →

Insider Decisions last twelve months

Bought, $m 0.86
Sold, $m 1,323.53
Trades a month
Jan 26 Apr 26 Jul 26 Oct 26
Buy — — — — — 1 — — — — — —
Sell 20 11 10 37 32 32 30 25 23 25 24 5
Insider Ownership 2.88%

Capital & Financial Ratios $m

Size
Market Cap 24,260.00
Revenue ttm 3,187.50
Net income ttm 1,230.80
Free cash flow ttm 867.20
Net debt Q (3,535.70)
Valuation
P/E 19.75
Forward P/E 22.50
Price / sales 7.57
Forward P/S Powerpack
Price / FCF 27.99
Price / book 3.77
Financial health
Current ratio Q 4.66 (at or above 1.5: strong)
Debt / equity Q 0.00 (at or below 0.5: strong)
Interest coverage Q 106.14
Growth
Revenue growth Q +4.13% (above 0%: growing)
Operating income growth Q −20.77% (below 0%: shrinking)
EPS, this year −11.92% (below 0%: weak)
EPS, next year A +21.70% (at or above 15%: strong)
Revenue, next year A −0.15% (below 0%: weak)
EPS, past 5 yrs +19.28% (at or above 15%: strong)
EPS, next 5 yrs A +8.45%

Green and red mark values outside typical ranges; (Q) is the latest quarter, (A) analysts’ estimates. How we judge →

Valuation vs history

P/E against its own 10 years 96.48%
10-year low 10-year high
P/S against its own 10 years 97.87%
10-year low 10-year high
P/B against its own 10 years 96.26%
10-year low 10-year high
EV/Sales against its own 10 years 96.59%
10-year low 10-year high
EV/FCF against its own 10 years 99.56%
10-year low 10-year high

Dividends

Yield
—
Annual rate
—
Payout ratio
—

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 2,994 3,267 2,920 3,536
Receivables 279 279 350 —
Inventory 112 158 183 —
Other 166 170 249 —
3,551 3,874 3,703 3,536
2023 2024 2025 Q'26
Payables 298 345 488 —
ST’ Debt 400 300 — —
Other 106 94 73 —
804 738 561 758

Compound Annual Growth %

10y 5y 3y
Sales 8.06% 16.50% 18.02%
Cash Flow 15.09% 15.62% 24.84%
Earnings 7.43% 20.99% 22.43%
Book Value 16.15% 15.89% 13.94%

Earnings Trends EPS, adjusted, against the consensus

EPS $

Mar Jun Sep Dec Year
’26 5.82 7.27 5.71 — —
’25 6.63 6.41 7.16 7.70 27.86
’24 6.17 5.85 6.39 6.19 24.64
’23 4.86 5.24 5.38 4.36 19.81
’22 5.03 2.41 4.91 2.67 15.00
’21 0.61 3.65 3.42 2.35 10.06
’20 3.12 2.41 3.84 2.19 11.54
Fiscal quarters ending in the months shown.

Revenue $m

Mar Jun Sep Dec Year
’26 782 783 833 — —
’25 794 799 800 790 3,183
’24 678 715 749 736 2,877
’23 507 597 609 615 2,328
’22 462 467 516 492 1,936
’21 379 447 445 415 1,686
’20 356 362 380 385 1,483
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 463 314 — — —
’25 461 192 562 346 1,561
’24 377 232 377 341 1,327
’23 375 106 346 151 978
’22 289 127 259 128 803
’21 90 148 186 175 598
’20 215 164 251 126 756
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 363 206 126 — —
’25 386 130 346 173 1,035
’24 338 187 301 255 1,081
’23 334 62 281 72 748
’22 275 110 190 89 664
’21 79 132 162 104 477
’20 202 146 238 114 699
Fiscal quarters ending in the months shown.

Valuation

The price implies free cash flow after share-based pay growing 11.9% a year for ten years. It grew 7.0% a year over the last ten.

Implied
11.9%
10 years, reported
7.0%
Open the model

Target Price Range

Analyst price targets

Recommendation Rating

1.5
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Ten-year view Analyst estimates Powerpack
Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 TTM Sep ’26 Trend 10 yrs 2026e 2027e 2028e Next 3/yr
Income, $m
Income, $m Revenue 1,599 1,725 1,628 1,449 1,483 1,686 1,936 2,328 2,877 3,183 3,188 +7.9% 3,178 3,605 4,119 +9.0%
Gross margin, % 95.45 93.87 87.79 91.88 92.71 92.73 92.17 88.94 89.24 87.92 86.34 (7.5) pt
EBT 1,060 770 759 (165) 639 594 951 1,274 1,539 1,714 1,508 +5.5%
EBT margin, % 66.31 44.60 46.62 (11.39) 43.07 35.24 49.09 54.75 53.49 53.85 47.30 (12.5) pt
Net income 714 418 589 (104) 515 476 727 985 1,195 1,335 1,231 +7.2%
Per share, $
Per share, $ Revenue 36.50 39.21 37.42 33.08 33.56 37.54 42.56 49.73 63.66 71.84 74.65 +7.8%
Earnings 16.29 9.50 13.54 (2.39) 11.65 10.60 15.98 21.04 26.44 30.13 28.61 +7.1%
Cash flow 14.69 10.78 17.89 (4.72) 17.10 13.32 17.64 20.90 29.36 35.24 33.48 +10.2%
Capex (0.87) (1.77) (4.24) (1.91) (1.29) (2.69) (3.05) (4.92) (5.45) (11.87) (13.17) +33.7%
Free cash flow 13.83 9.00 13.66 (6.63) 15.81 10.63 14.59 15.97 23.91 23.37 20.31 +6.0%
Book value 42.27 47.77 64.11 63.48 76.81 88.17 105.42 127.88 142.57 160.19 146.98 +16.0%
Shares, m 44 44 44 44 44 45 46 47 45 44 43 +0.1%
Valuation, ×
Valuation, × P/E 8.89 15.88 8.01 0.00 13.03 20.40 17.07 10.80 13.34 16.14 19.75 12.4
P/S 3.94 3.87 2.91 2.66 4.52 5.76 6.42 4.57 5.54 6.78 7.57 4.7
P/B 3.41 3.18 1.70 1.39 1.98 2.45 2.59 1.78 2.47 3.04 3.77 2.4
EV/Sales 3.29 3.63 2.35 2.22 3.99 5.23 5.50 3.59 4.55 5.96 6.55 4.0
EV/FCF 8.76 16.01 6.49 (10.90) 8.54 18.68 16.17 11.24 12.16 18.32 24.24 10.5
Cash, $m
Cash, $m Operating cash flow 644 474 778 (207) 756 598 803 978 1,327 1,561 1,430 +10.3%
Capex (38) (78) (184) (84) (57) (121) (139) (230) (246) (526) (562) +33.9%
Free cash flow 606 396 594 (290) 699 477 664 748 1,081 1,035 867 +6.1%
Balance, $m
Balance, $m Working capital 1,092 1,003 1,491 1,402 1,844 2,018 3,037 2,747 3,136 3,142 2,778 +12.5%
Net debt (1,051) (677) (1,166) (636) (1,035) (1,131) (2,039) (2,294) (2,967) (2,920) (3,536) +12.0%
Shareholders’ equity 1,851 2,102 2,789 2,780 3,395 3,959 4,797 5,985 6,444 7,096 6,276 +16.1%
Returns, %
Returns, % ROA 31.65 16.06 18.76 (2.86) 12.07 9.73 12.97 14.91 16.45 17.51 17.11 (14.1) pt
ROIC 82.89 35.76 31.02 (5.47) 15.72 12.28 22.20 20.07 24.75 22.34 30.13 (60.5) pt
ROE 41.50 21.14 24.10 (3.75) 16.67 12.94 16.61 18.27 19.23 19.71 19.13 (21.8) pt
People
People Employees 750 800 860 920 950 965 985 1,168 1,305 1,400 — +7.2%
Revenue/emp, $m 2.13 2.16 1.89 1.57 1.56 1.75 1.97 1.99 2.20 2.27 — +0.7%
Negative figures in brackets.
estimates

All 10 years →

Fiscal years to Dec 2025 · latest quarter Sep 2026 · fundamentals updated 5 Nov 2026

Business profile

Updated

United Therapeutics develops and sells medicines for people with serious diseases, particularly pulmonary arterial hypertension (PAH), a rare condition involving high blood pressure in the vessels leading from the heart to the lungs. It also develops technologies intended to expand the supply of transplantable organs.

Its pulmonary hypertension products offer several ways to take medicine. Tyvaso DPI is an inhaled dry powder, while Nebulized Tyvaso is an inhaled solution delivered through a nebulizer. Both are approved in the United States for PAH and for pulmonary hypertension associated with interstitial lung disease, or PH-ILD. Remodulin is continuously infused, and Orenitram and Adcirca are tablets for PAH. The company also sells pumps used to deliver Remodulin under the skin.

Where the money comes from and where it goes Fiscal 2025

Fiscal 2025: revenue by products and services, and margins
Tyvaso DPI 1,293 40.61%
Nebulized Tyvaso 586 18.40%
Remodulin 527 16.55%
Orenitram 497 15.61%
Unituxin 227 7.13%
Adcirca 30 0.94%
Other 24 0.75%
Gross margin 87.92%
Operating margin 46.89%
Pre-tax margin 53.85%

Revenue by segment since 2011

United Therapeutics Corporation vs peers in Drug Manufacturers Specialty & Generic (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
TAK Takeda Pharmaceutical Co. $67.7B 32.0× — +1.71% (above 0%: growing) −4.35% (below 0%: shrinking) +54.88% (above 0%: growing) 66.66% 16.51% Compare
TEVA Teva Pharmaceutical Industries Ltd. $48.7B 92.6× 30.7× −1.90% (below 0%: shrinking) −47.18% (below 0%: shrinking) −30.29% (below 0%: shrinking) 55.52% 16.25% Compare
HLN Haleon PLC Sponsored ADR $40.2B 20.5× 16.5× −0.32% (below 0%: shrinking) +40.00% (above 0%: growing) −42.94% (below 0%: shrinking) 62.88% 25.36% Compare
ZTS Zoetis Inc. $33.9B 13.4× 14.2× −0.24% (below 0%: shrinking) +2.48% (above 0%: growing) +17.43% (above 0%: growing) 72.73% 37.56% Compare
UTHR United Therapeutics Corporation $24.3B 19.7× 22.5× +4.13% (above 0%: growing) −21.65% (below 0%: shrinking) −63.65% (below 0%: shrinking) 88.10% 36.97%
VTRS Viatris Inc. $21.8B — (loss-making) 82.6× −0.28% (below 0%: shrinking) n/m +38.78% (above 0%: growing) 38.35% 6.97% Compare
NBIX Neurocrine Biosciences, Inc. $16.2B 23.0× 20.6× +41.24% (above 0%: growing) −3.67% (below 0%: shrinking) +79.00% (above 0%: growing) 97.63% 29.51% Compare
RDY Dr. Reddy's Laboratories Ltd $12.1B 44.4× 30.7× −10.09% (below 0%: shrinking) −36.84% (below 0%: shrinking) −70.49% (below 0%: shrinking) 52.13% 14.63% Compare
ELAN Elanco Animal Health Incorporated $11.8B — (loss-making) 161× +10.23% (above 0%: growing) +450.00% (above 0%: growing) +35.56% (above 0%: growing) 58.33% 7.97% Compare
Median of peers $27.9B 27.5× 30.7× −0.26% −3.67% +26.50% 60.61% 16.38%

All 84 Drug Manufacturers Specialty & Generic stocks →

Analyst rating changes each firm’s latest, last six months

Firm Date Action Rating Target
Goldman Sachs Oct 20, 2026 Initiated Sell —
Cantor Oct 1, 2026 Reiterated Outperform 700.00
BTIG Oct 1, 2026 Upgrade Buy 728.00

Largest institutional holders 13F, quarter to 30 June 2026

Held by institutions 97.36%
Held by the ten largest 47.75%
Holder Shares Stake Change
BlackRock 5.29m 12.41% −105.12k
Vanguard 4.17m 9.77% −125.55k
Avoro Capital Advisors LLC 2.78m 6.51% +147.78k
State Street 1.90m 4.45% +54.10k
RENAISSANCE TECHNOLOGIES LLC 1.71m 4.00% −78.28k
Wellington Management 1.38m 3.23% −885.22k
Geode Capital Management 996.60k 2.34% −236.43k
Jupiter Topco 831.13k 1.95% +831.13k
Norges Bank 694.75k 1.63% +694.75k
ASSETMARK, INC 624.07k 1.46% +8.02k
13F filings for the quarter to 30 June 2026: long positions in US-listed shares reported by managers with $100m or more, ~45 days after the quarter.

Pay and ownership Proxy statement filed 29 April 2026

Chief executive’s pay

Year Total pay Actually paid $100 invested
2025 18.04m 149.88m 321.00
2024 23.01m 120.26m 232.45
2023 16.96m (10.81m) 144.86
2022 5.32m 41.19m 183.21
2021 3.51m 50.43m 142.35

Ownership

Directors and executive officers, together 8.60%
BlackRock, Inc. 12.50%
Avoro Capital Advisors LLC 6.80%
Martine Rothblatt 6.50%
Wellington Management Group LLP 5.80%
Total pay is as the Summary Compensation Table states it; actually paid revalues the year’s share awards at its end, as the SEC’s pay-versus-performance rule asks. $100 invested is what $100 in the company’s shares at the start of the earliest year shown was worth at each year’s end. Ownership is the proxy’s own table: the directors and officers as a group, and every holder of 5% or more. Read the proxy statement

United Therapeutics Corporation (UTHR) Latest News

24 Oct

Impact 3 · · Simply Wall St.

16 Oct

UTHR metrics, ten years each

stockrow.com/UTHR · Data as of Nov 5, 2026 · For information only; not investment advice. · © 2026 stockrow.com