Entrada Therapeutics, Inc.

TRDA

Healthcare Biotechnology

Entrada Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $25.4 million, down 87.9% from fiscal 2024.

Revenue
−43.9%
EPS
+11.3%
Free cash flow
−7.05%

Quarter to September 2026, against a year earlier

4.89 0.34 +7.47%
Market cap
$191.5M
P/E
n/m
Fwd P/E
n/m
Dividend yield
—
F-score
3/9
Net debt / EBITDA
1.9×
Dividend safety
n/a

Insider Decisions last twelve months

Net sold
$11.5M
Trades
18 sells · 1 buy
Ownership
43.6%

Capital & Financial Ratios $m

Size
Market Cap 191
Revenue ttm 4
Net income ttm (161)
Free cash flow ttm (136)
Net debt Q (193)
Valuation
P/E n/m
Forward P/E n/m
Price / sales 52.1 (above 10: high)
Forward P/S Powerpack
Price / FCF n/m
Price / book 1.0
Financial health
Current ratio Q 7.8 (at or above 1.5: strong)
Debt / equity Q n/m
Interest coverage Q —
Growth
Revenue growth Q −43.9% (below 0%: shrinking)
Operating income growth Q +11.4% (above 0%: growing)
EPS, this year −11.4% (below 0%: weak)
EPS, next year A +8.5%
Revenue, next year A −87.6% (below 0%: weak)
EPS, past 5 yrs —
EPS, next 5 yrs A +2.2%

Green and red mark values outside typical ranges; (Q) is the latest quarter, (A) analysts’ estimates; n/m is not meaningful, as a P/E on a loss. How we judge →

Valuation vs history

P/B against its own 10 years 27.01%
10-year low 10-year high

Dividends

Yield
—
Annual rate
—
Payout ratio
—

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 352 420 296 193
Receivables 6 4 1 1
Inventory — — — —
Other — — — —
370 440 306 203
2023 2024 2025 Q'26
Payables 3 4 2 5
ST’ Debt — — — —
Other — — — —
159 39 24 26

Compound Annual Growth %

10y 5y 3y
Sales — — —
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 50.11% 12.93%

Earnings Trends EPS, adjusted, against the consensus

EPS $

Mar Jun Sep Dec Year
’26 (0.95) (1.01) (0.94) — —
’25 (0.42) (1.04) (1.06) (0.94) (3.47)
’24 0.68 1.55 (0.35) 0.03 1.68
’23 (0.21) (0.78) 1.02 (0.29) (0.20)
’22 (0.69) (0.74) (0.80) (0.79) (3.02)
’21 (6.67) (7.56) (9.78) (0.89) (8.16)
’20 — — (6.13) — (24.00)
Fiscal quarters ending in the months shown.

Revenue $m

Mar Jun Sep Dec Year
’26 1 1 1 — —
’25 21 2 2 1 25
’24 59 95 20 37 211
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (42) (32) (30) — —
’25 (39) (29) (28) (32) (129)
’24 (26) 40 (24) (32) (42)
’23 203 (35) (24) (4) 140
’22 (21) (18) (27) (27) (94)
’21 (8) (8) (14) (21) (51)
’20 — — (19) (7) (26)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (42) (32) (30) — —
’25 (40) (30) (28) (32) (130)
’24 (26) 39 (25) (32) (45)
’23 202 (37) (26) (5) 134
’22 (22) (19) (28) (28) (97)
’21 (9) (9) (15) (22) (55)
’20 — — (20) (8) (28)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.3
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Ten-year view Analyst estimates Powerpack
Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 TTM Sep ’26 Trend 10 yrs 2026e 2027e 2028e Next 3/yr
Income, $m
Income, $m Revenue — — — — — — — 129 211 25 4 (55.6%) 3 20 20 (7.8%)
Gross margin, % — — — 0.00 0.00 0.00 0.00 100.00 100.00 100.00 100.00 +100.0 pt
EBT — — — (5) (27) (51) (95) 12 66 (143) (161) +74.3%
EBT margin, % — — — 0.00 0.00 0.00 0.00 9.34 31.54 (561.84) (4,053.16) (561.8) pt
Net income — 0 — (5) (27) (51) (95) (7) 66 (144) (161) n/m
Per share, $
Per share, $ Revenue — — — 0.00 0.00 0.00 0.00 3.90 5.65 0.61 0.09 n/m
Earnings — — — (5.47) (24.00) (8.16) (3.02) (0.20) 1.76 (3.47) (3.84) (7.3%)
Cash flow — — — (11.58) (23.13) (8.11) (3.00) 4.23 (1.11) (3.11) (3.22) (19.7%)
Capex — — — (0.68) (2.10) (0.73) (0.09) (0.17) (0.08) (0.03) 0.00 (42.2%)
Free cash flow — — — (12.25) (25.23) (8.85) (3.09) 4.06 (1.20) (3.13) (3.22) (20.3%)
Book value — — — 17.47 36.34 47.66 6.79 7.33 11.49 7.40 4.68 (13.3%)
Shares, m — — — 1 1 6 31 33 37 41 42 +88.1%
Valuation, ×
Valuation, × P/E — — — — — — — 0.00 8.69 0.00 0.00 2.9
P/S — — — — — — — 3.89 3.06 16.73 52.10 7.9
P/B — — — — — — — 2.07 1.50 1.39 1.04 1.7
EV/Sales — — — — — — — 1.16 1.07 5.07 3.57 2.4
EV/FCF — — — — — — — 1.11 (5.03) (1.00) (0.10) (1.6)
Cash, $m
Cash, $m Operating cash flow — — — (11) (26) (51) (94) 140 (42) (129) (136) +51.1%
Capex — — — (1) (2) (5) (3) (6) (3) (1) 0 +8.7%
Free cash flow — — — (11) (28) (55) (97) 134 (45) (130) (136) +49.9%
Balance, $m
Balance, $m Working capital — — — 16 37 292 188 211 401 282 177 +62.1%
Net debt — — — (17) (39) (291) (189) (352) (420) (296) (193) +61.3%
Shareholders’ equity — — — 16 40 299 213 242 429 306 198 +63.0%
Returns, %
Returns, % ROA — — — (55.93) (85.88) (29.29) (33.92) (1.85) 13.18 (31.81) (47.48) +24.1 pt
ROIC — — — 0.00 (1,484.14) (417.49) (254.93) 0.00 338.50 (1,009.37) (2,008.96) (1,009.4) pt
ROE — — — 17.89 93.05 (39.78) (37.01) (2.94) 19.56 (39.13) (59.88) (57.0) pt
People
People Employees — — — — 78 114 130 159 183 152 — +14.3%
Revenue/emp, $m — — — — 0.00 0.00 0.00 0.81 1.15 0.17 — n/m
Negative figures in brackets.
estimates

All 10 years →

Fiscal years to Dec 2025 · latest quarter Sep 2026 · fundamentals updated 5 Nov 2026

Entrada Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
TRDA Entrada Therapeutics, Inc. $191.5M — (loss-making) — (loss-making) −43.93% (below 0%: shrinking) n/m −7.05% (below 0%: shrinking) 100.00% (4,606.52%)
CGEN Compugen Ltd. $185.7M 5.2× — (loss-making) +107.00% (above 0%: growing) n/m −155.42% (below 0%: shrinking) (3.54%) (339.62%) Compare
MDWD MediWound Ltd. $184.0M — (loss-making) — (loss-making) −45.83% (below 0%: shrinking) n/m −49.90% (below 0%: shrinking) 10.90% (305.89%) Compare
BCYC Bicycle Therapeutics PLC Sponsored ADR $182.5M — (loss-making) — (loss-making) +190.24% (above 0%: growing) n/m +43.48% (above 0%: growing) 100.00% (39.57%) Compare
ACOG Alpha Cognition Inc. $180.5M — (loss-making) — (loss-making) +267.56% (above 0%: growing) n/m −109.25% (below 0%: shrinking) 94.80% (127.29%) Compare
WHWK Whitehawk Therapeutics, Inc. $178.4M — (loss-making) — (loss-making) +33.48% (above 0%: growing) n/m +72.57% (above 0%: growing) 89.36% 0.00% Compare
UPB Upstream Bio, Inc. $176.9M — (loss-making) — (loss-making) −17.50% (below 0%: shrinking) n/m +9.33% (above 0%: growing) 100.00% (5,480.98%) Compare
IVVD Invivyd, Inc. $166.0M — (loss-making) — (loss-making) +21.20% (above 0%: growing) n/m −226.89% (below 0%: shrinking) 91.09% (320.76%) Compare
BBOT BridgeBio Oncology Therapeutics, Inc $163.6M — (loss-making) — — n/m −88.78% (below 0%: shrinking) — 0.00% Compare
Median of peers $179.5M — — +33.48% — −69.34% 91.09% (216.59%)

All 621 Biotechnology stocks →

Pay and ownership Proxy statement filed 24 April 2026

Ownership

Directors and executive officers, together 9.49%
Entities affiliated with Baker Bros. Advisors LP 19.51%
Entities affiliated with MPM Capital 11.40%
Entities affiliated with 10.45%
Roche Finance Ltd 6.62%
BlackRock, Inc. 5.09%
Ownership is the proxy’s own table: the directors and officers as a group, and every holder of 5% or more. Read the proxy statement

Entrada Therapeutics, Inc. (TRDA) Latest News

5 Nov

21 Oct

8 May

Impact 4 · · clinicaltrialsarena.com

9 Jan

Impact 4 · · TipRanksMT NewswiresMT NewswiresMT NewswiresMT NewswiresMT Newswires

30 Dec

Impact 4 · · 24/7 Wall St.
stockrow.com/TRDA · Data as of Nov 5, 2026 · For information only; not investment advice. · © 2026 stockrow.com