PTC Therapeutics, Inc.

PTCT Healthcare Biotechnology

PTC Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $1.7 billion, up 114.5% from fiscal 2024. In the quarter to June 2026, revenue grew 101.6%, EPS grew 221.7%, free cash flow grew 295.7% and total debt rose 21.6%, each against the same quarter a year earlier. Operating cash flow growth for three consecutive years.

59.24 1.75 −2.87%
Market cap
$5.1B
P/E
0.0×
Fwd P/E
110×
Dividend yield
—
F-score
7/9
Altman Z
1.86
Beneish M
−1.48
Dividend safety
n/a

Insider Decisions trades per month

Total sells 56.62
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — — — — — —
Sell 6 5 16 8 5 4 3 6 5 4 3 3
Insider Ownership 2.57%

Capital & Financial Ratios $m

Market Cap 5,090.00
Revenue 1,008.75
Net Income (38.38)
Free Cash Flow (300.25)
Net Debt 683.32
Current Ratio 3.39 (at or above 1.5: strong)
Debt/Equity (17.61) (negative: negative equity)
P/E ratio 0.00
Fwd P/E 110.00 (above 35: high)
P/S ratio 4.87
P/B ratio 0.00
Past 5Y EPS Growth —
This Y EPS Growth (83.86%) (below 0%: weak)
Next Y EPS Growth 95.69% (at or above 15%: strong)
Next Y revenue growth (27.37%) (below 0%: weak)
Next 5Y EPS Growth (19.48%) (below 0%: weak)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 39.70%
10-year low 10-year high
EV/Sales against its own 10 years 46.12%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2017 Powerpack
predictions special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 877 1,140 1,945 2,229
Receivables 161 159 182 239
Inventory 31 23 80 91
Other — — — —
1,219 1,366 2,274 2,617
2023 2024 2025 Q'26
Payables 392 304 381 382
ST’ Debt 194 258 570 370
Other — — — —
603 581 968 771

Compound Annual Growth %

10y 5y 3y
Sales 46.99% 35.37% 35.30%
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value 0.00% 0.00% 0.00%

Revenue $m

Mar Jun Sep Dec Year
’26 273 361 — — —
’25 1,176 179 211 165 1,731
’24 210 187 197 213 807
’23 220 214 197 307 938
’22 149 166 217 167 699
’21 118 117 139 165 539
’20 68 75 118 119 381
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (59) 129 — — —
’25 870 (58) (66) (34) 711
’24 71 (71) (77) (30) (108)
’23 (29) (14) (15) (100) (158)
’22 (97) (55) (38) (166) (357)
’21 (100) (31) (51) (69) (251)
’20 (82) (75) 27 (64) (194)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (60) 122 — — —
’25 868 (62) (322) (37) 702
’24 6 (36) (143) (37) (154)
’23 (73) (33) (90) (129) (279)
’22 (179) (73) (64) (193) (509)
’21 (120) (39) (99) (93) (337)
’20 (99) (77) (2) (83) (250)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.03) 0.92 — — —
’25 10.04 (0.83) 0.20 (1.67) 7.78
’24 (1.20) (1.29) (1.39) (0.85) (4.73)
’23 (1.88) (2.66) (1.76) (2.06) (8.37)
’22 (1.78) (2.13) (1.53) (2.35) (7.79)
’21 (1.83) (1.68) (1.89) (2.03) (7.43)
’20 (1.81) (2.78) (1.03) (1.08) (6.64)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.7
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low 4.03 8.12 16.38 27.53 30.79 34.85 25.01 17.53 23.58 35.95

Analyst estimates 2026–2028

Powerpack
High 31.89 22.00 52.95 50.96 68.81 70.82 55.58 59.84 54.16 87.50
People
People Employees 304 373 517 761 967 1,177 1,410 995 939 991
Revenue/emp, $m 0.27 0.52 0.51 0.40 0.39 0.46 0.50 0.94 0.86 1.75
Income, $m
Income, $m Revenue 83 194 265 307 381 539 699 938 807 1,731
Gross margin, % 100.00 97.65 95.21 96.05 95.03 94.00 93.61 93.02 92.89 97.28
EBT (142) (78) (128) (240) (403) (518) (587) (696) (363) 697
EBT margin, % (171.14) (39.95) (48.39) (78.16) (105.82) (96.24) (84.07) (74.23) (45.01) 40.25
Net income (142) (79) (128) (252) (438) (524) (559) (627) (363) 683
Depreciation 5 19 26 31 86 71 166 454 224 22
Per share, $
Per share, $ Revenue 2.43 4.96 5.68 5.22 5.77 7.64 9.74 12.53 10.50 21.76
Earnings (4.17) (2.02) (2.75) (4.27) (6.64) (7.43) (7.79) (8.37) (4.73) 8.58
Cash flow (3.04) (0.26) (0.59) (1.68) (2.94) (3.57) (4.97) (2.12) (1.40) 8.94
Capex (0.05) (2.05) (0.33) (0.77) (0.85) (1.21) (2.13) (1.61) (0.60) (0.11)
Free cash flow (3.09) (2.31) (0.93) (2.45) (3.79) (4.78) (7.10) (3.73) (2.00) 8.83
Book value 3.51 3.99 7.53 10.10 7.30 0.02 (4.84) (10.94) (14.29) (2.58)
Shares, m 34 39 47 59 66 70 72 75 77 80
Valuation, ×
Valuation, × P/E 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 8.64
P/S 4.62 3.52 6.04 9.21 10.58 5.21 3.92 2.24 4.30 3.49
P/B 3.20 4.37 4.56 4.76 8.36 1,951.79 0.00 0.00 0.00 0.00
EV/Sales 3.01 3.28 5.76 8.00 10.34 5.98 5.26 3.56 5.84 3.87
EV/FCF (2.36) (48.47) (43.87) (16.52) (14.43) (8.86) (7.22) (10.25) (20.35) 15.10
Cash, $m
Cash, $m Operating cash flow (104) (10) (28) (99) (194) (251) (357) (158) (108) 711
Capex (2) (80) (16) (45) (56) (85) (152) (121) (46) (9)
Free cash flow (105) (90) (43) (144) (250) (337) (509) (279) (154) 702
Balance, $m
Balance, $m Working capital 212 167 154 543 954 445 288 616 785 1,306
Total debt 98 145 153 314 1,012 1,185 1,348 2,115 2,383 2,598
Net debt (133) (46) (75) (373) (92) 412 938 1,239 1,243 653
Shareholders’ equity 120 156 351 594 482 1 (347) (819) (1,098) (205)
Returns, %
Returns, % ROA (44.79) (23.90) (16.95) (18.34) (22.87) (25.27) (30.68) (34.80) (20.18) 29.66
ROIC 0.00 (36.48) (26.18) (68.01) (69.14) (56.59) (47.36) (65.37) (130.42) 121.13
ROE (82.24) (57.24) (50.51) (53.24) (81.42) (216.75) 323.46 107.51 37.91 (104.75)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Charts ten years each

PTC Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
CGON CG Oncology, Inc. $5.5B — (loss-making) — (loss-making) +2,125.00% (above 0%: growing) n/m −67.60% (below 0%: shrinking) (239.24%) (7,467.68%) Compare
MIRM Mirum Pharmaceuticals, Inc. $5.4B — (loss-making) — (loss-making) +37.92% (above 0%: growing) n/m −681.46% (below 0%: shrinking) 82.78% (24.14%) Compare
ERAS Erasca, Inc. $5.2B — (loss-making) — — n/m −4.67% (below 0%: shrinking) 0.00% 0.00% Compare
COGT Cogent Biosciences, Inc. $5.1B — (loss-making) — (loss-making) −69.41% (below 0%: shrinking) n/m −42.01% (below 0%: shrinking) 0.00% 0.00% Compare
PTCT PTC Therapeutics, Inc. $5.1B — (loss-making) 110× +101.55% (above 0%: growing) n/m +295.69% (above 0%: growing) 94.47% 41.32%
CRSP CRISPR Therapeutics AG $5.0B — (loss-making) — (loss-making) +1,041.37% (above 0%: growing) n/m +26.19% (above 0%: growing) 100.00% (1,151.84%) Compare
TVTX Travere Therapeutics, Inc. $5.0B — (loss-making) 196× +48.17% (above 0%: growing) n/m +604.22% (above 0%: growing) 98.72% 2.33% Compare
SRRK Scholar Rock Holding Corporation $5.0B — (loss-making) — (loss-making) +605.03% (above 0%: growing) n/m +8.88% (above 0%: growing) 0.00% 0.00% Compare
ORKA Oruka Therapeutics, Inc. $4.9B — (loss-making) — — n/m −43.00% (below 0%: shrinking) 0.00% 0.00% Compare
Median of peers $5.1B — — +326.60% — −23.34% 0.00% 0.00%

All 614 Biotechnology stocks →

PTC Therapeutics, Inc. (PTCT) key facts

  • Strength: PTC Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $1.7 billion, up 114.5% from fiscal 2024.
  • PTC Therapeutics, Inc. (PTCT) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, PTCT traded at $59.24, a market capitalization of $5.1 billion.
  • Return on equity was −104.8% and debt-to-equity -17.61.
  • Its Piotroski F-score is 7 out of 9 and its Altman Z-score is 1.86 (grey zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

PTC Therapeutics, Inc. (PTCT) Latest News

stockrow.com/PTCT · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com