PTC Therapeutics, Inc.

PTCT Healthcare Biotechnology

PTC Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $1.7 billion, up 114.5% from fiscal 2024.

Revenue
+69.6%
EPS
−409.7%
Free cash flow
+90.3%
Total debt
+19.3%

Quarter to September 2026, against a year earlier

65.55 0.12 −0.18%
Market cap
$5.5B
P/E
0.0×
Fwd P/E
42.2×
Dividend yield
—
F-score
7/9
Altman Z
1.86
Beneish M
−1.48
Dividend safety
n/a

PTC Therapeutics, Inc. (PTCT) Operating margin

Alert me on Operating margin

PTC Therapeutics, Inc.'s operating margin over the twelve months to 30 September 2026 was 12.8%, down 37.3 percentage points from fiscal 2025 (50.1%). Over the past ten years it has ranged from −454.6% (fiscal 2015) to 50.1% (fiscal 2025) — the current reading is the highest in ten years. That is above the Biotechnology industry median of 0.00% and above the Healthcare sector median of 0.00%.

Operating margin, annual

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Annual newest first

Period Operating margin Change (points)
FY2025 50.1% 87.59
FY2024 −37.5% 9.36
FY2023 −46.9% 17.17
FY2022 −64.0% 5.49
FY2021 −69.5% 43.87
FY2020 −113.4% (34.83)
FY2019 −78.6% (34.86)
FY2018 −43.7% (10.63)
FY2017 −33.1% 126.60
FY2016 −159.7% 294.91

Quarterly newest first

Period Operating margin Change (points)
Sep 2026 7.02% (34.30)
Jun 2026 41.3% 24.82
Mar 2026 16.5% 59.83
Dec 2025 −43.3% (44.76)
43 more quarters

Against its own ten years

Low −454.6% High 50.1%
Ten-year median −64.0%
Current reading's percentile 91

Operating margin against peers

Company Operating margin
PTCT PTC Therapeutics, Inc. 12.8%
COGT Cogent Biosciences, Inc. compare 0.00%
KOD Kodiak Sciences Inc. compare 0.00%
IMVT Immunovant, Inc. compare 0.00%
MANE Veradermics Incorporated compare 0.00%
SRRK Scholar Rock Holding Corporation compare 0.00%
BLTE Belite Bio, Inc. Sponsored ADR compare 0.00%
MIRM Mirum Pharmaceuticals, Inc. compare −133.6%
CGON CG Oncology, Inc. compare −4,056.2%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Operating margin is

EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.

EBIT ÷ Revenue

The full definition of Operating margin →

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