Personalis, Inc.

PSNL Healthcare Diagnostics & Research

Personalis, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $69.6 million, down 17.7% from fiscal 2024. In the quarter to June 2026, revenue grew 30.0%, EPS fell 30.4% and free cash flow fell 123.5%, each against the same quarter a year earlier. Insiders bought in the last twelve months.

15.65 0.28 −1.76%
Market cap
$1.7B
P/E
0.0×
Fwd P/E
−10.5×
Dividend yield
—
F-score
4/9
Altman Z
3.35
Beneish M
−1.30
Dividend safety
n/a

Insider Decisions trades per month

Total buys 2.74
Total sells 8.78
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy 1 — — — — — — — — — — —
Sell 2 — 1 — — — 2 4 2 — 4 —
Insider Ownership 31.75%

Capital & Financial Ratios $m

Market Cap 1,700.00
Revenue 69.67
Net Income (107.18)
Free Cash Flow (100.85)
Net Debt (212.66)
Current Ratio 5.28 (at or above 1.5: strong)
Debt/Equity 0.00 (at or below 0.5: strong)
P/E ratio 0.00
Fwd P/E (10.50) (negative: loss-making)
P/S ratio 23.68 (above 10: high)
P/B ratio 7.02 (above 6: high)
Past 5Y EPS Growth —
This Y EPS Growth (19.51%) (below 0%: weak)
Next Y EPS Growth 13.79%
Next Y revenue growth 21.09% (at or above 10%: strong)
Next 5Y EPS Growth 10.38%

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 97.71%
10-year low 10-year high
P/B against its own 10 years 94.50%
10-year low 10-year high
EV/Sales against its own 10 years 96.70%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2018 Powerpack
predictions special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 114 185 240 213
Receivables 18 8 16 15
Inventory 10 6 6 10
Other — — — —
147 203 268 245
2023 2024 2025 Q'26
Payables 15 6 13 16
ST’ Debt — — — —
Other 8 3 2 3
47 31 40 46

Compound Annual Growth %

10y 5y 3y
Sales — (2.40%) 2.30%
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 6.02% 6.19%

Revenue $m

Mar Jun Sep Dec Year
’26 15 22 — — —
’25 21 17 14 17 70
’24 20 23 26 17 85
’23 19 17 18 20 73
’22 15 18 15 17 65
’21 21 22 22 21 85
’20 19 19 20 20 79
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (22) (26) — — —
’25 (18) (13) (22) (22) (75)
’24 (20) (11) (6) (8) (45)
’23 (16) (10) (17) (13) (56)
’22 (11) (27) (15) (17) (70)
’21 (12) (26) (18) (15) (71)
’20 (9) (15) (16) (3) (43)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (26) (30) — — —
’25 (20) (13) (23) (22) (79)
’24 (21) (11) (6) (9) (47)
’23 (20) (13) (18) (17) (67)
’22 (20) (38) (36) (26) (120)
’21 (12) (30) (21) (19) (82)
’20 (9) (16) (18) (3) (46)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.29) (0.30) — — —
’25 (0.18) (0.23) (0.24) (0.26) (0.91)
’24 (0.26) (0.24) (0.64) (0.23) (1.37)
’23 (0.61) (0.50) (0.60) (0.54) (2.25)
’22 (0.63) (0.60) (0.58) (0.67) (2.48)
’21 (0.29) (0.34) (0.40) (0.45) (1.49)
’20 (0.29) (0.29) (0.27) (0.34) (1.20)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

3.2
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low — — — 8.48 4.27 11.62 1.73 0.89 1.12 2.83

Analyst estimates 2026–2028

Powerpack
High — — — 31.88 46.80 53.46 14.57 4.31 7.20 11.40
People
People Employees — — 147 182 235 326 399 225 229 260
Revenue/emp, $m — 0.00 0.26 0.36 0.33 0.26 0.16 0.33 0.37 0.27
Income, $m
Income, $m Revenue — 9 38 65 79 85 65 73 85 70
Gross margin, % — (24.94) 31.25 33.86 25.57 37.03 20.52 24.78 31.70 22.65
EBT — (24) (20) (25) (41) (65) (113) (108) (81) (81)
EBT margin, % — (251.18) (52.63) (38.45) (52.41) (76.28) (174.14) (147.27) (96.04) (116.66)
Net income — (24) (20) (25) (41) (65) (113) (108) (81) (81)
Depreciation — 1 3 5 6 8 8 9 8 6
Per share, $
Per share, $ Revenue — 3.10 12.33 3.62 2.29 1.95 1.42 1.53 1.43 0.78
Earnings — (7.78) (6.49) (1.39) (1.20) (1.49) (2.48) (2.25) (1.37) (0.91)
Cash flow — 0.10 1.82 (1.00) (1.24) (1.61) (1.54) (1.17) (0.76) (0.84)
Capex — (1.70) (2.56) (0.47) (0.09) (0.25) (1.09) (0.23) (0.02) (0.05)
Free cash flow — (1.61) (0.74) (1.47) (1.34) (1.87) (2.63) (1.39) (0.78) (0.89)
Book value — 0.00 (34.73) 5.92 5.67 7.07 4.77 2.69 3.43 2.93
Shares, m — 3 3 18 34 44 46 48 59 89
Valuation, ×
Valuation, × P/E — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
P/S — 0.00 0.00 3.01 16.00 7.33 1.41 1.34 4.05 10.20
P/B — 0.00 0.00 1.84 6.46 2.02 0.42 0.76 1.69 2.72
EV/Sales — 0.00 0.00 1.32 13.65 4.18 (0.89) 0.03 2.07 7.01
EV/FCF — (21.53) (21.53) (3.25) (23.38) (4.36) 0.48 (0.03) (3.77) (6.15)
Cash, $m
Cash, $m Operating cash flow — 0 6 (18) (43) (71) (70) (56) (45) (75)
Capex — (5) (8) (8) (3) (11) (50) (11) (1) (5)
Free cash flow — (5) (2) (26) (46) (82) (120) (67) (47) (79)
Balance, $m
Balance, $m Working capital — (23) (28) 90 180 287 167 100 172 228
Total debt — 18 6 2 11 60 49 — — —
Net debt — (23) (20) (128) (203) (287) (168) (114) (185) (240)
Shareholders’ equity — — (106) 107 195 310 218 129 203 261
Returns, %
Returns, % ROA — (62.73) (95.45) (25.21) (20.53) (20.34) (32.88) (41.83) (32.82) (26.89)
ROIC — 0.00 0.00 0.00 0.00 (175.78) (143.04) (450.20) (237.72) (259.21)
ROE — 23.72 19.99 (16,611.92) (27.37) (25.82) (42.89) (62.31) (48.91) (35.02)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Charts ten years each

Personalis, Inc. vs peers in Diagnostics & Research (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
BLLN BillionToOne, Inc. $4.9B 95.0× 99.4× +64.40% (above 0%: growing) n/m +400.65% (above 0%: growing) 70.45% 5.03% Compare
ADPT Adaptive Biotechnologies Corporation $4.1B — (loss-making) — (loss-making) +21.53% (above 0%: growing) n/m +42.04% (above 0%: growing) 71.82% (22.04%) Compare
VCYT Veracyte, Inc. $3.6B 29.9× 45.1× +15.49% (above 0%: growing) n/m +32.95% (above 0%: growing) 72.21% 15.29% Compare
CDNA CareDx, Inc. $3.5B 29.7× 2,967× +52.23% (above 0%: growing) n/m +223.42% (above 0%: growing) 73.50% 85.81% Compare
NEO NeoGenomics, Inc. $2.2B — (loss-making) — (loss-making) +11.21% (above 0%: growing) n/m −16.18% (below 0%: shrinking) 45.56% (4.85%) Compare
WGS GeneDx Holdings Corp. $2.1B — (loss-making) — (loss-making) +11.44% (above 0%: growing) n/m −585.59% (below 0%: shrinking) 68.37% (15.25%) Compare
PSNL Personalis, Inc. $1.7B — (loss-making) — (loss-making) +29.96% (above 0%: growing) n/m −123.46% (below 0%: shrinking) 21.21% (150.25%)
OPK OPKO Health, Inc. $1.2B — (loss-making) — (loss-making) +4.32% (above 0%: growing) n/m +46.46% (above 0%: growing) 48.92% (4.26%) Compare
CSTL Castle Biosciences, Inc. $1.0B — (loss-making) — (loss-making) +20.14% (above 0%: growing) n/m −43.33% (below 0%: shrinking) 77.11% (2.96%) Compare
Median of peers $2.8B 29.9× 99.4× +17.82% — +37.50% 71.13% (3.61%)

All 52 Diagnostics & Research stocks →

Personalis, Inc. (PSNL) key facts

  • Concern: Personalis, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $69.6 million, down 17.7% from fiscal 2024.
  • Concern: Personalis, Inc. reported a net loss of $81.3 million, or a loss of $0.91 per share, for fiscal 2025.
  • Personalis, Inc. (PSNL) is a Diagnostics & Research company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, PSNL traded at $15.65, a market capitalization of $1.7 billion.
  • Trailing earnings are negative, so a P/E ratio is not meaningful; the stock trades at 23.7× sales.
  • Return on equity was −35.0% and debt-to-equity 0.00.
  • Its Piotroski F-score is 4 out of 9 and its Altman Z-score is 3.35 (safe zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

Personalis, Inc. (PSNL) Latest News

stockrow.com/PSNL · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com