Saturday 17 October 2026
Export MIST’s income statement to Excel — free account
Milestone Pharmaceuticals Inc.
MIST Healthcare Biotechnology
Milestone Pharmaceuticals Inc.’s revenue for fiscal 2025 (year ended December 2025) was $1.5 million, up 54.6% from fiscal 2023. In the quarter to June 2026, revenue fell 62.7%, EPS fell 5.00%, free cash flow fell 80.8% and total debt rose 7.19%, each against the same quarter a year earlier.
0.71
0.09
−11.25%
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Target Price Range
Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Trend | 2026e | 2027e | 2028e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Price, $ | |||||||||||||||
| Price, $ | Low | — | — | — | 12.36 | 1.69 | 5.09 | 3.39 | 1.62 | 1.12 | 0.63 |
Analyst estimates 2026–2028 Powerpack |
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| High | — | — | — | 27.95 | 23.25 | 9.03 | 9.85 | 4.49 | 2.75 | 3.06 | |||||
| People | |||||||||||||||
| People | Employees | — | — | 23 | 30 | 28 | 29 | 39 | 47 | 33 | 38 | ||||
| Revenue/emp, $m | — | — | 0.00 | 0.00 | 0.00 | 0.52 | 0.13 | 0.02 | 0.00 | 0.04 | |||||
| Income, $m | |||||||||||||||
| Income, $m | Revenue | — | — | — | — | — | 15 | 5 | 1 | — | 2 | ||||
| Gross margin, % | — | 0.00 | 0.00 | 0.00 | 0.00 | 100.00 | 100.00 | 100.00 | — | 100.00 | |||||
| EBT | — | (8) | (23) | (55) | (50) | (43) | (58) | (60) | (42) | (63) | |||||
| EBT margin, % | — | 0.00 | 0.00 | 0.00 | 0.00 | (285.69) | (1,167.76) | (5,968.50) | 0.00 | (4,078.78) | |||||
| Net income | — | (8) | (23) | (55) | (50) | (43) | (58) | (60) | (42) | (63) | |||||
| Depreciation | — | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||||
| Per share, $ | |||||||||||||||
| Per share, $ | Revenue | — | 0.00 | 0.00 | 0.00 | 0.00 | 0.36 | 0.12 | 0.02 | 0.00 | 0.02 | ||||
| Earnings | — | (34.15) | (72.63) | (3.50) | (1.70) | (1.02) | (1.38) | (1.39) | (0.67) | (0.75) | |||||
| Cash flow | — | (34.00) | (65.93) | (3.24) | (1.73) | (0.79) | (1.24) | (1.08) | (0.46) | (0.58) | |||||
| Capex | — | (0.15) | (0.02) | (0.03) | 0.00 | 0.00 | (0.01) | 0.00 | 0.00 | 0.00 | |||||
| Free cash flow | — | (34.16) | (65.95) | (3.27) | (1.73) | (0.79) | (1.24) | (1.08) | (0.46) | (0.59) | |||||
| Book value | — | (139.86) | (172.96) | 7.28 | 4.88 | 2.69 | 1.56 | 0.39 | 0.21 | 0.50 | |||||
| Shares, m | — | 0 | 0 | 16 | 29 | 42 | 42 | 43 | 62 | 84 | |||||
| Valuation, × | |||||||||||||||
| Valuation, × | P/E | — | — | — | — | — | 0.00 | 0.00 | 0.00 | — | 0.00 | ||||
| P/S | — | — | — | — | — | 0.00 | 0.00 | 3.68 | — | 8.07 | |||||
| P/B | — | — | — | — | — | 2.43 | 2.59 | 4.61 | — | 4.06 | |||||
| EV/Sales | — | — | — | — | — | 0.00 | 0.00 | 2.91 | — | 5.75 | |||||
| EV/FCF | — | — | — | — | — | (4.77) | (2.07) | (1.31) | — | (2.45) | |||||
| Cash, $m | |||||||||||||||
| Cash, $m | Operating cash flow | — | (8) | (21) | (51) | (51) | (33) | (52) | (46) | (29) | (49) | ||||
| Capex | — | 0 | 0 | 0 | — | — | 0 | 0 | 0 | 0 | |||||
| Free cash flow | — | (8) | (21) | (52) | (51) | (33) | (53) | (47) | (29) | (49) | |||||
| Balance, $m | |||||||||||||||
| Balance, $m | Working capital | — | 26 | 84 | 114 | 143 | 112 | 66 | 66 | 66 | 98 | ||||
| Total debt | — | — | — | 0 | 1 | 0 | 2 | 50 | 53 | 57 | |||||
| Net debt | — | (27) | (86) | (120) | (142) | (114) | (63) | (16) | (16) | (49) | |||||
| Shareholders’ equity | — | (33) | (55) | 115 | 143 | 113 | 66 | 17 | 13 | 42 | |||||
| Returns, % | |||||||||||||||
| Returns, % | ROA | — | (13.98) | (40.09) | (52.22) | (36.55) | (31.76) | (60.09) | (79.73) | (55.09) | (66.71) | ||||
| ROIC | — | 0.00 | 0.00 | 0.00 | (2,105.90) | 0.00 | (991.65) | (7,071.53) | 0.00 | 0.00 | |||||
| ROE | — | 18.31 | 52.50 | (185.00) | (38.73) | (33.52) | (65.26) | (143.61) | (277.55) | (229.65) | |||||
Negative figures in brackets.
Fiscal years to Dec 2025 · latest quarter Jun 2026
Charts ten years each
Milestone Pharmaceuticals Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| UNCY Unicycive Therapeutics, Inc. | $100.0M | — (loss-making) | — (loss-making) | — | n/m | +9.77% (above 0%: growing) | 0.00% | 0.00% | Compare |
| BDTX Black Diamond Therapeutics, Inc. | $100.0M | — (loss-making) | — (loss-making) | — | n/m | +12.91% (above 0%: growing) | 100.00% | 0.00% | Compare |
| PYPD PolyPid Ltd. | $99.5M | — (loss-making) | — | — | n/m | −64.96% (below 0%: shrinking) | 0.00% | 0.00% | Compare |
| MIST Milestone Pharmaceuticals Inc. | $98.9M | — (loss-making) | — (loss-making) | −62.73% (below 0%: shrinking) | n/m | −80.81% (below 0%: shrinking) | 94.28% | (4,584.97%) | |
| CBUS Cibus, Inc. | $98.6M | — (loss-making) | — (loss-making) | +6.54% (above 0%: growing) | n/m | +31.62% (above 0%: growing) | 100.00% | (1,300.30%) | Compare |
| PMVP PMV Pharmaceuticals, Inc. | $97.4M | — (loss-making) | — | — | n/m | +20.27% (above 0%: growing) | 0.00% | 0.00% | Compare |
| NRXS Neuraxis, Inc. | $97.2M | — (loss-making) | — (loss-making) | +115.71% (above 0%: growing) | n/m | +29.76% (above 0%: growing) | 85.87% | (110.16%) | Compare |
| IMUX Immunic, Inc. | $96.9M | — (loss-making) | — | — | n/m | −26.79% (below 0%: shrinking) | 0.00% | 0.00% | Compare |
| ATRA Atara Biotherapeutics, Inc. | $96.9M | — (loss-making) | — (loss-making) | −96.42% (below 0%: shrinking) | n/m | +52.10% (above 0%: growing) | 69.68% | (749.21%) | Compare |
| Median of peers | $98.0M | — | — | +6.54% | — | +16.59% | 34.84% | 0.00% |
Milestone Pharmaceuticals Inc. (MIST) key facts
- Concern: Milestone Pharmaceuticals Inc. reported a net loss of $63.1 million, or a loss of $0.75 per share, for fiscal 2025.
- Strength: Milestone Pharmaceuticals Inc.’s revenue for fiscal 2025 (year ended December 2025) was $1.5 million, up 54.6% from fiscal 2023.
- Milestone Pharmaceuticals Inc. (MIST) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
- As of October 16, 2026, MIST traded at $0.71, a market capitalization of $98.9 million.
- Trailing earnings are negative, so a P/E ratio is not meaningful; the stock trades at 18.6× sales.
- Return on equity was −229.7% and debt-to-equity 3.25.
- Its Altman Z-score is −4.65 (distress zone) for fiscal 2025.