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Janux Therapeutics, Inc. JANX

We limit data available in the Overview Report for users who do not have Powerpack

Get access to target analyst prices, predictions, compound annual growth rates and more than four years of historical data.

Insider Decisions

Total sells
1.06
in millions of $
Nov 25 Feb 26 May 26 Aug 26
Buy
Sell 1 1 1 6 1 1
Insider Ownership
8.11%

Capital & Financial Ratios

Market Cap
1,030.00
Revenue
24.00
Net Income
(102.59)
Free Cash Flow
(41.92)
Net Debt
(970.91)
Current Ratio
16.35
Debt/Equity
0.00
P/E ratio
0.00
P/S ratio
43.51
P/B ratio
1.13
Past 5Y EPS Growth
(67.90%)
This Y EPS Growth
4.60%
Next Y EPS Growth
(53.18%)
Next 5Y EPS Growth
(22.06%)
in millions of $

Dividends

Payout Ratio
0.00
Annual Dividend Rate
Annual Dividend Yield
total individual payouts
2025 ‡‡‡
2024 ‡‡‡
2023 ‡‡‡
2022 ‡‡‡
2021 ‡‡‡
2020 ‡‡‡
2019 ‡‡‡
predictions in italic, special payouts not included in total or ratios

Assets vs Liabilities

2023 2024 2025 Q'26
Cash 344.03 1,025.17 966.57 970.91
Receivables 0.15
Inventory
Other
349.24 1,033.67 975.89 983.34
2023 2024 2025 Q'26
Payables 2.42 4.03 4.97 3.02
ST’ Debt
Other
13.03 17.46 25.00 60.15
in millions of $

Compound Annual Growth

10y 5y 3y
Sales ‡‡‡‡‡
Cash Flow ‡‡‡ ‡‡‡
Earnings ‡‡‡ ‡‡‡
Book Value ‡‡‡‡‡ ‡‡‡‡‡

Revenue

Mar Jun Sep Dec Year
’26 3.73 10.27
’25 10.00
10.00
’24 1.25 8.90 0.44 0.00
10.59
’23 2.05 1.06 2.52 2.46
8.08
’22 1.59 2.37 1.81 2.85
8.61
in millions of $

Operating Cash Flow

Mar Jun Sep Dec Year
’26 (12.34) 12.48
’25 (17.02) (23.81) (12.86) (28.54)
(82.23)
’24 (14.84) (10.02) (2.23) (16.72)
(43.81)
’23 (13.91) (15.05) (11.71) (9.90)
(50.57)
’22 (11.52) (6.07) (13.41) (11.91)
(42.92)
’21 5.56 (6.20) (5.85) (10.48)
(16.98)
’20 (0.88) (1.66) (1.08) (1.63)
(4.37)
in millions of $

Free Cash Flow

Mar Jun Sep Dec Year
’26 (12.61) 12.28
’25 (17.39) (24.29) (12.95) (28.65)
(83.28)
’24 (15.03) (10.12) (2.26) (16.77)
(44.17)
’23 (14.20) (15.63) (12.18) (10.42)
(52.42)
’22 (12.49) (6.97) (15.93) (13.97)
(49.37)
’21 5.41 (6.28) (5.93) (11.65)
(18.46)
’20 (0.88) (1.66) (1.08) (1.63)
(4.37)
in millions of $

EPS

Mar Jun Sep Dec Year
’26 (0.39) (0.35)
’25 (0.38) (0.55) (0.39) (0.51)
(1.83)
’24 (0.30) (0.11) (0.51) (0.36)
(1.28)
’23 (0.42) (0.42) (0.25) (0.25)
(1.32)
’22 (0.32) (0.41) (0.40) (0.39)
(1.52)
’21 (0.05) (0.62) (0.26) (0.33)
(1.39)
’20 (0.03) (0.06) (0.03)
(0.16)

Target Price Range

High
‡‡‡‡‡
‡‡‡‡
Average
‡‡‡‡‡
‡‡‡‡
Low
‡‡‡‡‡
‡‡‡‡

Recommendation Rating

1.5
1
Buy
2
3
Hold
4
5
Sell
2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028
‡‡‡‡‡ 9.39 5.65 7.79 13.62
Low Price
‡‡‡‡‡ 20.85 23.64 71.71 61.59
High Price
‡‡‡‡ ‡‡‡‡ 60 64 81 109
Employees
‡‡‡ ‡‡‡‡‡ 0.14 0.13 0.13 0.09
Revenue/Emp
‡‡‡‡‡ 8.61 8.08 10.59 10.00 ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡
Revenue
‡‡‡ ‡‡‡ ‡‡‡ 100.00% 100.00% 100.00% 100.00%
Gross Margin
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (63.06) (58.29) (68.99) (113.62)
EBT
‡‡‡ ‡‡‡ ‡‡‡‡‡ (732.22%) (721.18%) (651.62%) (1,136.25%) ‡‡‡ ‡‡‡ ‡‡‡
EBT Margin
‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (63.06) (58.29) (68.99) (113.62) ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡
Net Income
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (1.34) (5.73) (8.52) (15.54)
Depreciation
‡‡‡ ‡‡‡ ‡‡‡‡‡ 0.21 0.18 0.20 0.16 ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡
Revenue/Sh
‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (1.52) (1.32) (1.28) (1.83) ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡
Earnings/Sh
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (1.03) (1.15) (0.82) (1.33) ‡‡‡‡‡
Cash Flow/Sh
‡‡‡ ‡‡‡ ‡‡‡‡‡ (0.16) (0.04) (0.01) (0.02) ‡‡‡ ‡‡‡ ‡‡‡
Capex/Sh
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (1.19) (1.19) (0.82) (1.34)
Free CF/Sh
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 7.73 7.82 19.03 15.44
Book Value/Sh
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 41.47 44.02 53.75 61.97 ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡
Shares
‡‡‡ 0.00 0.00 0.00 0.00 ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡
PE Ratio
‡‡‡‡‡ 67.51 60.01 271.80 44.23 ‡‡‡ ‡‡‡ ‡‡‡
PS Ratio
‡‡‡‡‡ 1.81 1.41 2.81 0.89 ‡‡‡ ‡‡‡ ‡‡‡
PB Ratio
‡‡‡‡‡ 32.48 20.53 177.33 (4.47) ‡‡‡‡ ‡‡‡‡ ‡‡‡‡
EV/Sales
‡‡‡‡‡ (5.67) (3.16) (42.50) 1.04
EV/FCF
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (42.92) (50.57) (43.81) (82.23) ‡‡‡ ‡‡‡ ‡‡‡
Op' Cash Flow
‡‡‡‡‡ (6.44) (1.85) (0.36) (1.04) ‡‡‡‡‡ ‡‡‡‡‡
Capex
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (49.37) (52.42) (44.17) (83.28) ‡‡‡‡‡
FCF
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 315.93 336.21 1,016.21 950.89
Working Cap'
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 25.31
Total Debt
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (301.71) (344.03) (1,025.17) (966.57)
Net Debt
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 320.74 344.35 1,022.78 956.82
Sh' Equity
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (16.96%) (15.66%) (9.57%) (11.02%)
ROA
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡ (220.36%) (14,209.31%) 0.00% 0.00%
ROIC
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (18.36%) (17.53%) (10.09%) (11.48%)
ROE
predictions in italic, sparklines do not include predictions

Analyst Commentary (Summary)

Janux Therapeutics (JANX) is a high-stakes biotech bet on next-gen T-cell engagers targeting tough solid tumors like prostate and EGFR-driven cancers. As of early 2026, the stock lurks near lows, just 9% above the gloomiest analyst target but a massive 307% below the average and over 1,000% off the high—screaming high-risk, high-reward in a sector battered by post-IPO funding droughts and rate hikes. Yet, with revenue CAGR at 69% from partnerships like Gilead’s $1.2B deal, a fortress balance sheet boasting $1B+ in net cash for a 4-5 year runway, and escalating losses typical of clinical ramp-ups, JANX has insider conviction: a director’s $25M blockbuster buy in 2025 dwarfs minor sells.

The stock’s wild ride—from $71 peaks on Phase 1 data to 82% drawdowns—mirrors biotech whiplash, fueled by trial hype and macro fears, with valuations like 272x PS screaming future growth bets. Projections show near-term pain (revenue plunging 82% in 2026 amid -$250M losses), but Phase 2 readouts for leads JANX007/008 and potential buyouts could spark 300%+ upside to average targets, especially with Fed cuts thawing M&A.

This speculative gem trades at a discount to its cash pile and pipeline promise amid oncology booms, but trial flops or dilution loom. Dive into the full analysis for historicals, metrics, and why savvy insiders are loading up—could JANX be your biotech breakout?

Janux Therapeutics, Inc. (JANX) Latest News

News by impact score

Fine-tune

11 Aug

3 , 6:10 AM
Janux Therapeutics (JANX) stock rose 7.1% after the company reported narrower net losses and an improved earnings profile. Earnings improvement drives short-term stock gain but does not signal major strategic or competitive shifts.

6 Aug

3 , 5:20 PM
Janux Therapeutics posted a Q2 loss and missed revenue estimates. Q2 loss and revenue miss directly pressures near-term financial outlook and investor sentiment.

3 , 4:02 PM
Janux Therapeutics reported second quarter 2026 financial results and business highlights. Quarterly results and updates can shift near-term investor views on operations and pipeline progress.

30 Jun

3 , 9:06 AM
Janux Therapeutics, Inc. (JANX) is positioned around next-generation immunotherapy platforms targeting cancer, framing the stock as a potential biotech investment opportunity amid ongoing pipeline development. JANX immunotherapy pipeline progress can moderately shift investor sentiment and competitive positioning without confirmed major regulatory or commercial events.

28 May

3 IPO-Edge.com, 6:33 PM
Akari Therapeutics secures first-ever ASCO abstract acceptance. ASCO abstract acceptance indicates pipeline progress with moderate effects on biotech valuation and sentiment.

26 May

3 Zacks, 11:28 AM
Janux Therapeutics (JANX) presents investment potential that supports adding the stock to portfolios based on its current prospects and developments. Stock recommendation highlights possible positive investor sentiment but lacks details on major operational or regulatory shifts.

7 May

4 Business Wire, 4:01 PM
Janux Therapeutics reported first quarter 2026 financial results and business highlights. Quarterly financial results and business highlights for a clinical-stage biotech like JANX often drive significant shifts in investor sentiment and stock trajectory.

3 Zacks, 7:05 PM
Janux Therapeutics, Inc. (JANX) reported a Q1 loss and revenue below analyst estimates. Q1 loss and revenue miss highlight weaker financial results, potentially impacting short-term market sentiment and stock performance.

3 Zacks, 9:55 AM
Wall Street analysts forecast 180.44% upside remaining for Janux Therapeutics (JANX). Analyst consensus projecting 180.44% upside can moderately boost investor sentiment and short-term stock performance.

27 Apr

4 Business Wire, 4:01 PM
Janux Therapeutics announces discontinuation of JANX008 clinical development. Discontinuation of JANX008 removes a key pipeline asset, significantly harming Janux's development prospects and market valuation.

16 Apr

4 Business Wire, 4:01 PM
Janux Therapeutics dosed the first participant in the Phase 1 clinical trial of JANX014, a T cell engager targeting PSMA for prostate cancer. Dosing first patient in Phase 1 trial of JANX014 advances key oncology asset into clinical testing, likely boosting investor sentiment and stock performance amid biotech pipeline milestones.

3 Apr

4 Simply Wall St., 7:11 PM
Bristol-Myers Squibb's cancer treatment advances and Janux Therapeutics' equity financing efforts strengthen the valuation case for JANX. Bristol-Myers Squibb's oncology moves and Janux's equity initiatives provide significant validation, boosting JANX's market performance and trajectory.

2 Apr

4 Zacks, 2:29 PM
Janux Therapeutics secures $35 million milestone payment from its Bristol Myers Squibb (BMY) deal. $35M milestone from BMY deal provides significant non-dilutive cash, validating pipeline and enhancing financial position.

1 Apr

4 Business Wire, 8:01 AM
Janux Therapeutics nominates development candidate under Bristol Myers Squibb collaboration, triggering $35 million milestone payment. Development candidate nomination unlocks $35 million non-dilutive funding from Bristol Myers Squibb, validating pipeline progress and boosting financial runway.

2 Mar

4 Insider Monkey, 2:56 AM
Janux Therapeutics, Inc. (JANX) commences patient dosing of JANX011 in autoimmune trial. Commencing patient dosing in JANX011 autoimmune trial advances Janux's pipeline into new indications, likely driving significant positive investor sentiment and stock performance.

26 Feb

4 Business Wire, 4:01 PM
Janux Therapeutics reported fourth quarter and full-year 2025 financial results alongside key business highlights. Financial results and business highlights for a biotech firm like Janux often signal pipeline progress, funding status, or strategic shifts that significantly impact stock performance and investor outlook.

17 Feb

4 Business Wire, 7:00 AM
Janux Therapeutics dosed the first patient in the Phase 1 clinical study of JANX011, a T cell engager targeting PSMA for prostate cancer. Dosing the first patient in Phase 1 advances JANX011 through clinical development, boosting pipeline progress and investor sentiment for Janux's oncology focus.

3 Feb

4 Zacks, 9:55 AM
Wall Street analysts project a potential upside of 319.23% for Janux Therapeutics, Inc. (JANX), driven by positive developments in its pipeline and market positioning. The stock's current valuation suggests significant growth potential, attracting investor interest. Analysts highlight the company's innovative approach to drug development and its strategic partnerships as key factors that could propel its stock price higher. However, questions remain about the sustainability of this growth and the challenges that may arise in the competitive landscape. Analysts' projections indicate significant growth potential driven by strategic developments and market positioning.

2 Feb

4 Insider Monkey, 9:36 AM
Janux Therapeutics, Inc. (JANX) is facing platform risk due to insufficient durability data on its lead product candidate, JANX007. Concerns have been raised regarding the long-term effectiveness of the treatment, which could impact investor confidence and the company's future prospects. The lack of robust data may hinder the company's ability to advance its clinical programs and secure partnerships, raising questions about its overall strategy and market position. Insufficient durability data on JANX007 poses significant risks to the company's future performance and investor sentiment.

30 Jan

4 Zacks, 8:49 AM
Janux Therapeutics, Inc. is positioned to benefit from Bristol-Myers Squibb's oncology collaborations, which may enhance its growth potential. The partnerships are expected to leverage Janux's proprietary technology in developing innovative cancer therapies, potentially leading to significant advancements in treatment options. Analysts are optimistic about the synergies created through these collaborations, which could drive both companies' market performance in the oncology sector. Bristol-Myers Squibb's oncology collaborations are likely to significantly enhance Janux's growth trajectory and market positioning.

27 Jan

4 Insider Monkey, 6:09 PM
Janux Therapeutics, Inc. has entered into a partnership with Bristol-Myers Squibb to develop a novel therapy targeting solid tumors. This collaboration aims to leverage Janux's proprietary technology platform to enhance the efficacy of cancer treatments. The partnership is expected to accelerate the development of innovative therapies for patients with solid tumors, potentially leading to significant advancements in cancer care. The partnership with Bristol-Myers Squibb represents a significant strategic move that could enhance Janux's product offerings and market position in oncology.

26 Jan

3 Business Wire, 7:00 AM
Janux Therapeutics, Inc. has appointed William Go, M.D., Ph.D., as its new Chief Medical Officer. Dr. Go brings extensive experience in drug development and clinical research, having previously held leadership roles at various biopharmaceutical companies. His appointment is expected to enhance Janux's strategic direction and clinical initiatives as the company advances its pipeline of innovative therapies. The appointment of a seasoned CMO may positively influence Janux's clinical development and strategic direction, but the overall impact on the company's trajectory remains limited.

22 Jan

4 www.pharmaceutical-technology.com, 1:01 PM
Bristol Myers Squibb (BMS) has entered into an $850 million deal with Janux Therapeutics, Inc. to develop a novel therapy targeting solid tumors. This collaboration aims to leverage Janux's proprietary technology to enhance cancer treatment options. The agreement includes an upfront payment and potential milestone payments, reflecting BMS's commitment to expanding its oncology portfolio. Janux's innovative approach could significantly impact the landscape of solid tumor therapies. The partnership with BMS represents a major strategic move that could significantly enhance Janux's market position and future financial performance.

4 www.biopharmadive.com, 7:00 AM
Bristol Myers Squibb has made a strategic investment in Janux Therapeutics, Inc. by acquiring an equity stake and entering into a collaboration agreement. This partnership focuses on Janux's innovative 'masked' T cell engagers, which are designed to selectively target and eliminate cancer cells while minimizing damage to healthy tissues. The collaboration aims to advance the development of these therapies, potentially enhancing treatment options for patients with various cancers. Financial terms of the deal were not disclosed. The collaboration with Bristol Myers Squibb is likely to significantly enhance Janux's product development and market positioning in the competitive oncology landscape.

4 Business Wire, 7:00 AM
Janux Therapeutics, Inc. has entered into a collaboration and exclusive worldwide license agreement with Bristol Myers Squibb to develop a novel tumor-activated therapeutic aimed at treating solid tumors. This partnership is expected to leverage Janux's proprietary technology platform to enhance the efficacy of cancer treatments. The collaboration with Bristol Myers Squibb represents a significant strategic move that could enhance Janux's product offerings and market position in oncology.

27 Dec

4 Insider Monkey, 7:43 AM
Janux Therapeutics, Inc. (JANX) is gaining attention on Wall Street due to its innovative approach in developing targeted therapies for cancer treatment. The company's proprietary technology platform, which focuses on creating T cell engagers, has shown promising results in early clinical trials. Analysts highlight the potential for significant market impact as Janux advances its pipeline, particularly with its lead candidate, JANX-007, aimed at treating solid tumors. The growing interest from investors reflects optimism about the company's ability to address unmet medical needs and capture market share in the competitive oncology landscape. The advancement of Janux's innovative therapies and promising clinical trial results are likely to significantly impact its market performance and investor sentiment.

23 Dec

4 Business WireMT NewswiresMT NewswiresSimply Wall St., 4:05 PM
Janux Therapeutics, Inc. provided an update on its ongoing Phase 1 study of JANX008, a novel T cell engager targeting prostate-specific membrane antigen (PSMA). The study aims to evaluate the safety, tolerability, and preliminary efficacy of JANX008 in patients with advanced solid tumors. Initial data from the trial indicates a favorable safety profile, with some patients experiencing tumor reductions. The company remains focused on advancing the clinical development of JANX008 and plans to present further data at upcoming medical conferences. The update on the Phase 1 study suggests significant progress in clinical development, which could enhance investor sentiment and the company's market position.

12 Dec

4 www.barchart.com, 7:30 AM
Janux Therapeutics, Inc. (JANX) is highlighted as one of two biotech stocks with significant upside potential, estimated between 208% to 329%. The company is recognized for its innovative approach in developing therapies targeting cancer and other diseases. Analysts emphasize the strong market position and growth prospects of Janux, suggesting that its advancements in drug development could lead to substantial returns for investors. Janux Therapeutics is positioned for significant growth due to its innovative therapies and strong market potential.

6 Dec

4 Simply Wall St.Insider MonkeySimply Wall St.MT NewswiresZacksSimply Wall St.Simply Wall St.Simply Wall St., 6:09 AM
Janux Therapeutics, Inc. reported interim results for JANX007, highlighting the performance of its TRACTr platform in treating cancer. The results are being evaluated for their potential impact on the company's competitive positioning in the biopharmaceutical market. Analysts are closely watching how these findings may influence investor sentiment and the future trajectory of Janux's product development. The interim results of JANX007 could significantly impact Janux Therapeutics' competitive position and market performance.

4 Dec

3 , 10:16 PM
Janux Therapeutics, Inc. (JANX) reported positive Phase 1 data for its drug candidate JANX007, which targets cancer treatment. Despite this encouraging news, the company's share price experienced a sharp decline, raising questions about market sentiment and valuation. Analysts are now reassessing the company's future prospects in light of the data and the stock's performance. Positive Phase 1 data could influence investor sentiment and future financial performance, but the sharp share price drop indicates mixed market reactions.

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