Design Therapeutics, Inc.

DSGN Healthcare Biotechnology

In the quarter to June 2026, EPS grew 5.88% and free cash flow fell 7.00%, each against the same quarter a year earlier.

10.31 0.17 −1.62%
Market cap
$655.9M
P/E
0.0×
Fwd P/E
−1.6×
Dividend yield
—
F-score
n/a
Altman Z
n/a
Beneish M
n/a
Dividend safety
n/a

Insider Decisions trades per month

Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — — — — — —
Sell — — — — — — — — — — — —
Insider Ownership 44.68%

Capital & Financial Ratios $m

Market Cap 655.86
Revenue 0.23
Net Income (70.79)
Free Cash Flow (55.22)
Net Debt (207.40)
Current Ratio 18.86 (at or above 1.5: strong)
Debt/Equity 0.00 (at or below 0.5: strong)
P/E ratio 0.00
Fwd P/E (1.62) (negative: loss-making)
P/S ratio 2,851.44 (above 10: high)
P/B ratio 3.19
Past 5Y EPS Growth —
This Y EPS Growth (7.85%) (below 0%: weak)
Next Y EPS Growth (20.78%) (below 0%: weak)
Next Y revenue growth 19,944.25% (at or above 10%: strong)
Next 5Y EPS Growth (16.98%) (below 0%: weak)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 66.83%
10-year low 10-year high
P/B against its own 10 years 89.81%
10-year low 10-year high
EV/Sales against its own 10 years 65.31%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2023 Powerpack
2022 Powerpack
2021 Powerpack
special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 282 245 220 207
Receivables — — — —
Inventory — — — —
Other — — — —
285 248 224 212
2023 2024 2025 Q'26
Payables 2 2 2 3
ST’ Debt — — — —
Other — — — —
10 8 13 11

Compound Annual Growth %

10y 5y 3y
Sales — — —
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 0.00% (13.41%)

Revenue $m

Mar Jun Sep Dec Year
’26 — — — — —
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (16) (16) — — —
’25 (17) (14) (11) (12) (54)
’24 (12) (11) (10) (10) (43)
’23 (17) (14) (15) (13) (59)
’22 (12) (10) (14) (15) (51)
’21 (4) (8) (8) (9) (29)
’20 (3) (1) (2) (3) (9)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (16) (16) — — —
’25 (17) (15) (11) (12) (55)
’24 (13) (11) (10) (10) (43)
’23 (18) (14) (15) (13) (59)
’22 (12) (11) (14) (15) (52)
’21 (4) (8) (9) (10) (31)
’20 (3) (1) (2) (3) (9)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.29) (0.32) — — —
’25 (0.31) (0.34) (0.30) (0.27) (1.22)
’24 (0.20) (0.21) (0.23) (0.24) (0.88)
’23 (0.35) (0.36) (0.28) (0.21) (1.19)
’22 (0.24) (0.27) (0.32) (0.31) (1.14)
’21 (0.31) (0.14) (0.21) (0.20) (0.77)
’20 (0.04) (0.06) (0.09) (0.34) (0.52)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low — — — — — 12.52 6.94 1.94 2.25 2.60

Analyst estimates 2026–2028

Powerpack
High — — — — — 43.00 26.30 10.72 7.77 10.31
People
People Employees — — — — 20 38 58 58 54 54
Revenue/emp, $m — — — — 0.01 0.00 0.00 0.00 0.00 0.00
Income, $m
Income, $m Revenue — — — — 0 — — — — —
Gross margin, % — — — — 100.00 0.00 0.00 — — —
EBT — — — (2) (8) (36) (63) (67) (50) (70)
EBT margin, % — — — 0.00 (3,663.72) 0.00 0.00 0.00 0.00 0.00
Net income — 0 — (2) (8) (36) (63) (67) (50) (70)
Depreciation — — — — 0 0 (1) (6) (6) (3)
Per share, $
Per share, $ Revenue — — — 0.00 0.01 0.00 0.00 0.00 0.00 0.00
Earnings — — — (0.04) (0.52) (0.77) (1.14) (1.19) (0.88) (1.22)
Cash flow — — — 0.00 (0.55) (0.64) (0.92) (1.05) (0.76) (0.95)
Capex — — — 0.00 0.00 (0.03) (0.02) 0.00 (0.01) 0.00
Free cash flow — — — 0.00 (0.55) (0.67) (0.94) (1.05) (0.77) (0.95)
Book value — — — (0.07) (0.72) 8.32 5.88 4.96 4.28 3.71
Shares, m — — — 56 16 46 56 56 57 57
Valuation, ×
Valuation, × P/E — — — — 0.00 — — — — —
P/S — — — — 2,377.24 — — — — —
P/B — — — — 0.00 — — — — —
EV/Sales — — — — 2,217.54 — — — — —
EV/FCF — — — — (57.81) — — — — —
Cash, $m
Cash, $m Operating cash flow — — — 0 (9) (29) (51) (59) (43) (54)
Capex — — — — 0 (2) (1) 0 0 0
Free cash flow — — — 0 (9) (31) (52) (59) (43) (55)
Balance, $m
Balance, $m Working capital — — — (4) 34 380 324 275 240 211
Total debt — — — 1 — 4 4 — — —
Net debt — — — 1 (36) (384) (330) (282) (245) (220)
Shareholders’ equity — — — (4) (11) 382 327 278 242 213
Returns, %
Returns, % ROA — — — (4,548.89) (45.24) (16.64) (17.30) (21.20) (18.31) (29.18)
ROIC — — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00
ROE — — — 27.37 110.72 (19.16) (17.85) (22.10) (19.08) (30.70)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2020 · latest quarter Dec 2020

Charts ten years each

Design Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
ANNX Annexon, Inc. $682.5M — (loss-making) — — n/m −26.41% (below 0%: shrinking) 0.00% 0.00% Compare
MDXG MiMedx Group, Inc $682.2M 111× — (loss-making) −34.73% (below 0%: shrinking) n/m −174.83% (below 0%: shrinking) 68.96% (28.69%) Compare
CADL Candel Therapeutics, Inc. $681.8M — (loss-making) — (loss-making) 0.00% n/m −93.35% (below 0%: shrinking) 0.00% 0.00% Compare
PHAR Pharming Group N.V. Sponsored ADR $681.6M 62.4× — (loss-making) −3.22% (below 0%: shrinking) −57.14% (below 0%: shrinking) −183.87% (below 0%: shrinking) 83.92% 1.44% Compare
GYRE Gyre Therapeutics, Inc. $678.6M — (loss-making) — (loss-making) −2.12% (below 0%: shrinking) n/m −130.45% (below 0%: shrinking) 92.41% (49.35%) Compare
AURA Aura Biosciences, Inc. $657.5M — (loss-making) — — n/m −56.26% (below 0%: shrinking) 0.00% 0.00% Compare
DSGN Design Therapeutics, Inc. $655.9M — (loss-making) — (loss-making) — n/m −7.00% (below 0%: shrinking) 0.00% 0.00%
PRME Prime Medicine, Inc. $654.8M — (loss-making) — (loss-making) +3.50% (above 0%: growing) n/m +4.40% (above 0%: growing) 100.00% (3,750.87%) Compare
AVTX Avalo Therapeutics, Inc. $644.1M — (loss-making) — (loss-making) −70.14% (below 0%: shrinking) n/m +75.70% (above 0%: growing) 55.73% 0.00% Compare
Median of peers $680.1M — — −2.67% — −74.80% 62.35% 0.00%

All 614 Biotechnology stocks →

Design Therapeutics, Inc. (DSGN) key facts

  • Concern: Design Therapeutics, Inc. reported a net loss of $69.8 million, or a loss of $1.22 per share, for fiscal 2025.
  • Design Therapeutics, Inc. (DSGN) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, DSGN traded at $10.31, a market capitalization of $655.9 million.
  • Trailing earnings are negative, so a P/E ratio is not meaningful; the stock trades at 2,851× sales.
  • Return on equity was −30.7% and debt-to-equity 0.00.

Source: company filings (standardised) and stockrow calculations.

Design Therapeutics, Inc. (DSGN) Latest News

10 Jul

18 Apr

19 Feb

stockrow.com/DSGN · Data as of Dec 31, 2020 · For information only; not investment advice. · © 2026 stockrow.com