Design Therapeutics, Inc.

DSGN Healthcare Biotechnology

EPS
−7.27%
Free cash flow
−7.00%

Quarter to September 2026, against a year earlier

10.19 0.52 +5.38%
Market cap
$605.2M
P/E
0.0×
Fwd P/E
−1.6×
Dividend yield
—
F-score
n/a
Altman Z
n/a
Beneish M
n/a
Dividend safety
n/a

Insider Decisions last twelve months

Trades a month
Jan 26 Apr 26 Jul 26 Oct 26
Buy — — — — — — — — — — — —
Sell — — — — — — — — — — — —
Insider Ownership 45.14%

Capital & Financial Ratios $m

Size
Market Cap 605.16
Revenue ttm 0.23
Net income ttm (74.09)
Free cash flow ttm (59.37)
Net debt Q (208.61)
Valuation
P/E 0.00
Forward P/E (1.62) (negative: loss-making)
Price / sales 2,842.20 (above 10: high)
Forward P/S Powerpack
Price / FCF 0.00
Price / book 3.18
Financial health
Current ratio Q 16.78 (at or above 1.5: strong)
Debt / equity Q 0.00 (at or below 0.5: strong)
Interest coverage Q —
Growth
Revenue growth Q —
Operating income growth Q −15.12% (below 0%: shrinking)
EPS, this year −6.12% (below 0%: weak)
EPS, next year A −17.97% (below 0%: weak)
Revenue, next year A +19,944.25% (at or above 10%: strong)
EPS, past 5 yrs —
EPS, next 5 yrs A −14.85% (below 0%: weak)

Green and red mark values outside typical ranges; (Q) is the latest quarter, (A) analysts’ estimates. How we judge →

Valuation vs history

P/S against its own 10 years 66.01%
10-year low 10-year high
P/B against its own 10 years 89.00%
10-year low 10-year high
EV/Sales against its own 10 years 63.56%
10-year low 10-year high

Dividends

Yield
—
Annual rate
—
Payout ratio
—

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 282 245 220 209
Receivables — — — —
Inventory — — — —
Other — — — —
285 248 224 214
2023 2024 2025 Q'26
Payables 2 2 2 2
ST’ Debt — — — —
Other — — — —
10 8 13 13

Compound Annual Growth %

10y 5y 3y
Sales — — —
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 0.00% (13.41%)

Earnings Trends EPS, adjusted, against the consensus

EPS $

Mar Jun Sep Dec Year
’26 (0.29) (0.32) (0.32) — —
’25 (0.31) (0.34) (0.30) (0.27) (1.22)
’24 (0.20) (0.21) (0.23) (0.24) (0.88)
’23 (0.35) (0.36) (0.28) (0.21) (1.19)
’22 (0.24) (0.27) (0.32) (0.31) (1.14)
’21 (0.31) (0.14) (0.21) (0.20) (0.77)
’20 (0.04) (0.06) (0.09) (0.34) (0.52)
Fiscal quarters ending in the months shown.

Revenue $m

Mar Jun Sep Dec Year
’26 — — — — —
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (16) (16) (15) — —
’25 (17) (14) (11) (12) (54)
’24 (12) (11) (10) (10) (43)
’23 (17) (14) (15) (13) (59)
’22 (12) (10) (14) (15) (51)
’21 (4) (8) (8) (9) (29)
’20 (3) (1) (2) (3) (9)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (16) (16) (15) — —
’25 (17) (15) (11) (12) (55)
’24 (13) (11) (10) (10) (43)
’23 (18) (14) (15) (13) (59)
’22 (12) (11) (14) (15) (52)
’21 (4) (8) (9) (10) (31)
’20 (3) (1) (2) (3) (9)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Ten-year view Analyst estimates Powerpack
Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 TTM Sep ’26 Trend 10 yrs 2026e 2027e 2028e Next 3/yr
Income, $m
Income, $m Revenue — — — — 0 — — — — — 0 — 5 5 5 0.0%
Gross margin, % — — — — 100.00 0.00 0.00 — — — 0.00 (100.0) pt
EBT — — — (2) (8) (36) (63) (67) (50) (70) (74) +80.1%
EBT margin, % — — — 0.00 (3,663.72) 0.00 0.00 0.00 0.00 0.00 0.00 0.0 pt
Net income — 0 — (2) (8) (36) (63) (67) (50) (70) (74) n/m
Per share, $
Per share, $ Revenue — — — 0.00 0.01 0.00 0.00 0.00 0.00 0.00 0.00 n/m
Earnings — — — (0.04) (0.52) (0.77) (1.14) (1.19) (0.88) (1.22) (1.20) +76.8%
Cash flow — — — 0.00 (0.55) (0.64) (0.92) (1.05) (0.76) (0.95) (0.94) +169.0%
Capex — — — 0.00 0.00 (0.03) (0.02) 0.00 (0.01) 0.00 0.00 n/m
Free cash flow — — — 0.00 (0.55) (0.67) (0.94) (1.05) (0.77) (0.95) (0.94) +169.2%
Book value — — — (0.07) (0.72) 8.32 5.88 4.96 4.28 3.71 3.21 n/m
Shares, m — — — 56 16 46 56 56 57 57 61 +0.5%
Valuation, ×
Valuation, × P/E — — — — 0.00 — — — — — 0.00 —
P/S — — — — 2,900.08 — — — — — 2,842.20 —
P/B — — — — 0.00 — — — — — 3.18 —
EV/Sales — — — — 2,740.38 — — — — — 1,919.15 —
EV/FCF — — — — (71.44) — — — — — (7.31) —
Cash, $m
Cash, $m Operating cash flow — — — 0 (9) (29) (51) (59) (43) (54) (59) +170.4%
Capex — — — — 0 (2) (1) 0 0 0 0 +20.5%
Free cash flow — — — 0 (9) (31) (52) (59) (43) (55) (59) +170.6%
Balance, $m
Balance, $m Working capital — — — (4) 34 380 324 275 240 211 201 n/m
Net debt — — — 1 (36) (384) (330) (282) (245) (220) (209) n/m
Shareholders’ equity — — — (4) (11) 382 327 278 242 213 202 n/m
Returns, %
Returns, % ROA — — — (4,548.89) (45.24) (16.64) (17.30) (21.20) (18.31) (29.18) (34.57) +4,519.7 pt
ROIC — — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.0 pt
ROE — — — 27.37 110.72 (19.16) (17.85) (22.10) (19.08) (30.70) (36.87) (58.1) pt
People
People Employees — — — — 20 38 58 58 54 54 — +22.0%
Revenue/emp, $m — — — — 0.01 0.00 0.00 0.00 0.00 0.00 — n/m
Negative figures in brackets.
estimates

All 10 years →

Fiscal years to Dec 2020 · latest quarter Dec 2020 · fundamentals updated 6 Nov 2026

Design Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
DBVT DBV Technologies S.A. $615.8M — (loss-making) — −42.86% (below 0%: shrinking) n/m −64.93% (below 0%: shrinking) 100.00% (4,043.75%) Compare
CADL Candel Therapeutics, Inc. $615.2M — (loss-making) — (loss-making) 0.00% n/m −93.35% (below 0%: shrinking) 0.00% 0.00% Compare
HELP Cybin Inc. $613.0M — (loss-making) — (loss-making) — n/m −25.60% (below 0%: shrinking) 0.00% 0.00% Compare
GERN Geron Corporation $610.4M — (loss-making) — (loss-making) +27.45% (above 0%: growing) n/m +176.13% (above 0%: growing) 89.95% 9.63% Compare
DSGN Design Therapeutics, Inc. $605.2M — (loss-making) — (loss-making) — n/m −7.00% (below 0%: shrinking) 0.00% 0.00%
KURA Kura Oncology, Inc. $604.9M — (loss-making) — (loss-making) +36.54% (above 0%: growing) n/m −109.05% (below 0%: shrinking) 98.84% (349.77%) Compare
AVBP ArriVent BioPharma, Inc. $603.0M — (loss-making) — — n/m −51.51% (below 0%: shrinking) — 0.00% Compare
IMMX Immix Biopharma, Inc. $596.9M — (loss-making) — — n/m −116.22% (below 0%: shrinking) — 0.00% Compare
OBX Obsidian Therapeutics, Inc $593.0M — — — n/m — — 0.00% Compare
Median of peers $607.7M — — +13.73% — −64.93% 89.95% 0.00%

All 621 Biotechnology stocks →

Pay and ownership Proxy statement filed 23 April 2026

Ownership

Directors and executive officers, together 17.10%
Aseem Z. Ansari, Ph.D. 12.40%
Simeon George, M.D. 10.60%
SR One Capital Fund I Aggregator, LP 10.50%
Point72 Asset Management, L.P. 8.60%
Light Irrevocable Trust #1 dated April 6.10%
Star Irrevocable Trust #1 dated April 6.10%
Quan Venture Fund II, L.P. 5.40%
Ownership is the proxy’s own table: the directors and officers as a group, and every holder of 5% or more. Read the proxy statement

Design Therapeutics, Inc. (DSGN) Latest News

10 Sep

10 Jul

Impact 3 · · Simply Wall St.

22 May

Impact 3 · · Simply Wall St.

2 May

18 Apr

12 Mar

19 Feb

Impact 3 · · Simply Wall St.

21 Jan

Impact 4 · · Simply Wall St.
stockrow.com/DSGN · Data as of Nov 6, 2026 · For information only; not investment advice. · © 2026 stockrow.com