Harmony Biosciences Holdings, Inc.

HRMY Healthcare Biotechnology

Harmony Biosciences Holdings, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $868.5 million, up 21.5% from fiscal 2024.

Revenue
+12.3%
EPS
−6.24%
Free cash flow
−29.4%
Total debt
−11.5%

Quarter to September 2026, against a year earlier

33.04 0.57 +1.76%
Market cap
$1.9B
P/E
10.7×
Fwd P/E
9.9×
Dividend yield
—
F-score
5/9
Altman Z
5.23
Beneish M
−2.99
Dividend safety
n/a

Harmony Biosciences Holdings, Inc. (HRMY) Operating margin

Alert me on Operating margin

Harmony Biosciences Holdings, Inc.'s operating margin over the twelve months to 30 September 2026 was 22.2%, down 1.8 percentage points from fiscal 2025 (24.0%). Over the past ten years it has ranged from −2,433.8% (fiscal 2019) to 33.0% (fiscal 2023); the current reading is higher than 50% of that period. That is above the Biotechnology industry median of 0.00% and above the Healthcare sector median of 0.00%.

Operating margin, annual

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Annual newest first

Period Operating margin Change (points)
FY2025 24.0% (2.70)
FY2024 26.7% (6.29)
FY2023 33.0% 5.54
FY2022 27.5% (1.21)
FY2021 28.7% 18.03
FY2020 10.6% 2,444.39
FY2019 −2,433.8% (2,433.76)
FY2018 0.00% —

Quarterly newest first

Period Operating margin Change (points)
Sep 2026 20.2% (14.03)
Jun 2026 34.2% 16.87
Mar 2026 17.3% 1.49
Dec 2025 15.8% (11.53)
24 more quarters

Against its own ten years

Low −2,433.8% High 33.0%
Ten-year median 25.4%
Current reading's percentile 17

Operating margin against peers

Company Operating margin
HRMY Harmony Biosciences Holdings, Inc. 22.2%
FTRE Fortrea Holdings Inc. compare 0.48%
REPL Replimune Group, Inc. compare 0.00%
TRAX First Tracks Biotherapeutics, Inc. compare 0.00%
MAZE Maze Therapeutics, Inc. compare 0.00%
TRVI Trevi Therapeutics, Inc. compare 0.00%
SRPT Sarepta Therapeutics, Inc. compare −2.50%
VIR Vir Biotechnology, Inc. compare −69.8%
MESO Mesoblast Limited compare −826.3%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Operating margin is

EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.

EBIT ÷ Revenue

The full definition of Operating margin →

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