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Harmony Biosciences Holdings, Inc. (HRMY) vs Trevi Therapeutics, Inc. (TRVI)

Harmony Biosciences Holdings, Inc. and Trevi Therapeutics, Inc. are both Biotechnology companies. Harmony Biosciences Holdings, Inc. and Trevi Therapeutics, Inc. are of similar size ($1.9B and $1.8B). Trevi Therapeutics, Inc. has negative trailing earnings, so its P/E is not meaningful; Harmony Biosciences Holdings, Inc. trades at 10.7×. Harmony Biosciences Holdings, Inc. has the higher net margin (18.1% vs 0.00%) and the higher return on invested capital (30.5% vs −1,412.1%). Across the 14 metrics below, Harmony Biosciences Holdings, Inc. leads on 11 and Trevi Therapeutics, Inc. on 3.

Valuation

Metric HRMY TRVI Biotechnology median
P/E 10.74 n/m 10.60
P/S 1.95 n/m 9.40
P/B 1.80 6.93 2.13
Price to free cash flow 6.83 n/m 25.18
EV/EBITDA 5.37 n/m 0.66
EV/Sales 1.32 n/m 9.02
Earnings yield 9.31% (2.39%) (32.88%)
Free cash flow yield 14.65% (2.37%) (23.13%)

Profitability

Metric HRMY TRVI Biotechnology median
Gross margin 74.03% 0.00% 68.51%
Operating margin 22.17% 0.00% 0.00%
Net margin 18.05% 0.00% 0.00%
Free cash flow margin 32.65% 0.00% 0.00%
Return on equity 18.73% (19.66%) (51.96%)
Return on assets 13.30% (18.97%) (46.06%)
Return on invested capital 30.45% (1,412.11%) 0.00%

Growth

Metric HRMY TRVI Biotechnology median
Revenue growth (TTM) 19.79% — 6.76%
EPS growth (last fiscal year) 7.97% 31.91% 29.88%
Revenue growth, 5-year CAGR 40.30% — 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric HRMY TRVI Biotechnology median
Debt to equity 0.14 0.00 0.00
Current ratio 3.44 37.28 4.97
Net debt to EBITDA (2.63) 3.83 1.01

Dividend

Metric HRMY TRVI Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric HRMY TRVI Biotechnology median
Market cap 1.89b 1.83b 161.82m

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