Ensysce Biosciences, Inc.

ENSC Healthcare Biotechnology

Ensysce Biosciences, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $5.1 million, down 2.75% from fiscal 2024. In the quarter to June 2026, revenue fell 15.1%, EPS grew 74.7% and free cash flow grew 27.5%, each against the same quarter a year earlier. Insiders bought in the last twelve months.

0.52 0.08 −13.33%
Market cap
$11.6M
P/E
0.0×
Fwd P/E
−0.1×
Dividend yield
—
F-score
3/9
Altman Z
−29.36
Beneish M
−1.90
Dividend safety
n/a

Insider Decisions trades per month

Total buys 0.44
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — 1 — — — — — —
Sell — — — — — — — — — — — —
Insider Ownership 0.00%

Capital & Financial Ratios $m

Market Cap 11.64
Revenue 4.50
Net Income (12.62)
Free Cash Flow (8.86)
Net Debt (0.68)
Current Ratio 0.70 (below 1: weak)
Debt/Equity 0.00 (at or below 0.5: strong)
P/E ratio 0.00
Fwd P/E (0.13) (negative: loss-making)
P/S ratio 1.51
P/B ratio 0.00
Past 5Y EPS Growth —
This Y EPS Growth 72.61% (at or above 15%: strong)
Next Y EPS Growth 94.50% (at or above 15%: strong)
Next Y revenue growth (9.21%) (below 0%: weak)
Next 5Y EPS Growth —

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 56.46%
10-year low 10-year high
EV/Sales against its own 10 years 62.65%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2020 Powerpack
2019 Powerpack
2018 Powerpack
2017 Powerpack
special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 1 4 4 1
Receivables 0 0 0 0
Inventory — — — —
Other — — — —
2 5 7 3
2023 2024 2025 Q'26
Payables 2 1 3 2
ST’ Debt — — — —
Other — — — —
3 2 5 4

Compound Annual Growth %

10y 5y 3y
Sales — 5.21% 26.16%
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 0.00% 0.00%

Revenue $m

Mar Jun Sep Dec Year
’26 1 1 — — —
’25 1 1 0 2 5
’24 0 0 3 1 5
’23 1 0 0 1 2
’22 1 0 0 1 3
’21 0 0 1 2 4
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (4) (2) — — —
’25 (2) (3) (2) (2) (8)
’24 (3) (2) (1) (1) (8)
’23 (4) (3) (2) (2) (11)
’22 (3) (4) (7) (3) (18)
’21 (1) 0 (4) (4) (8)
’20 0 0 0 (1) (1)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (4) (2) — — —
’25 (2) (3) (2) (2) (8)
’24 (3) (2) (1) (1) (8)
’23 (4) (3) (2) (2) (11)
’22 (3) (4) (7) (3) (18)
’21 (1) 0 (4) (4) (8)
’20 0 0 0 (1) (1)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.52) (0.20) — — —
’25 (1.39) (0.79) (1.29) (0.75) (3.98)
’24 (8.25) (3.30) 1.05 (2.90) (11.45)
’23 (31.18) (14.69) (13.04) (16.94) (70.31)
’22 (215.98) (863.91) (923.31) (273.57) (2.09k)
’21 (207.26) (215.98) (2.56k) (1.62k) (5.33k)
’20 1.01k (161.27) 331.25 (1.22k) (35.08)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low — — 34,380.00 35,352.00 32,814.00 4,500.00 106.20 11.48 2.12 0.86

Analyst estimates 2026–2028

Powerpack
High — — 35,460.00 37,548.00 49,226.40 86,364.00 18,144.00 275.40 30.90 9.57
People
People Employees — 4 4 4 4 6 7 8 7 10
Revenue/emp, $m — 0.00 0.00 0.00 0.98 0.59 0.36 0.28 0.74 0.51
Income, $m
Income, $m Revenue — — — — 4 4 3 2 5 5
Gross margin, % — — — — 100.00 100.00 100.00 100.00 100.00 100.00
EBT — 0 3 (1) 0 (29) (24) (11) (8) (10)
EBT margin, % — 0.00 0.00 0.00 (4.09) (825.38) (959.33) (476.41) (153.30) (200.84)
Net income — 0 2 (1) 0 (29) (24) (11) (8) (10)
Depreciation — — — — 0 0 — 0 1 0
Per share, $
Per share, $ Revenue — 0.00 0.00 0.00 893.45 630.57 210.28 14.77 7.46 1.98
Earnings — 0.00 1,272.46 (631.68) 1,323.40 (5,327.47) (2,091.39) (70.31) (11.45) (3.98)
Cash flow — (0.20) (728.41) (838.12) (283.48) (1,471.82) (1,490.62) (71.39) (10.75) (3.05)
Capex — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 (0.05)
Free cash flow — (0.20) (728.41) (838.12) (283.48) (1,471.82) (1,490.62) (71.39) (10.75) (3.10)
Book value — 3.97 2,941.18 2,941.18 (1,513.27) (1,456.80) (335.81) (4.31) 4.84 1.13
Shares, m — 1 0 0 0 0 0 0 1 3
Valuation, ×
Valuation, × P/E — — — — 0.00 0.00 0.00 0.00 0.00 0.00
P/S — — — — 0.00 26.83 0.68 1.13 1.09 0.46
P/B — — — — 0.00 0.00 0.00 0.00 1.68 0.82
EV/Sales — — — — 0.00 24.81 (0.24) 0.99 0.57 (0.23)
EV/FCF — — — — (158.93) (10.63) 0.03 (0.20) (0.40) 0.15
Cash, $m
Cash, $m Operating cash flow — 0 (1) (1) (1) (8) (18) (11) (8) (8)
Capex — — — — — — — — — 0
Free cash flow — 0 (1) (1) (1) (8) (18) (11) (8) (8)
Balance, $m
Balance, $m Working capital — 2 1 (2) (7) (1) (4) (1) 3 3
Total debt — — — 1 1 4 0 — — —
Net debt — (2) (2) 0 1 (8) (3) (1) (4) (4)
Shareholders’ equity — 5 5 5 (7) (8) (4) (1) 3 3
Returns, %
Returns, % ROA — (0.02) 1.04 (0.53) 0.06 (356.45) (224.96) (247.31) (192.34) (155.95)
ROIC — 0.00 (17.94) (46.18) 0.00 0.00 0.00 0.00 0.00 0.00
ROE — (0.62) 42.44 (21.35) (6.85) 403.43 411.65 454.02 (585.44) (324.86)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Charts ten years each

Ensysce Biosciences, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
AEON AEON Biopharma, Inc. $12.1M — (loss-making) — — n/m −76.85% (below 0%: shrinking) — 0.00% Compare
ASBP Aspire-Lakewood Holdings, Inc. $12.1M 0.2× — — n/m −85.54% (below 0%: shrinking) (47.70%) (4,244.37%) Compare
ACTU Actuate Therapeutics, Inc. $12.0M — (loss-making) — — n/m −5.54% (below 0%: shrinking) — 0.00% Compare
PLUR Pluri Inc. $11.9M — (loss-making) — (loss-making) −15.83% (below 0%: shrinking) n/m +25.03% (above 0%: growing) 58.51% (1,655.52%) Compare
INAB IN8bio, Inc. $11.7M — (loss-making) — — n/m −1.30% (below 0%: shrinking) 0.00% 0.00% Compare
ENSC Ensysce Biosciences, Inc. $11.6M — (loss-making) — (loss-making) −15.10% (below 0%: shrinking) n/m +27.50% (above 0%: growing) 100.00% (221.28%)
PASG Passage Bio, Inc. $11.6M — (loss-making) — — n/m −59.81% (below 0%: shrinking) 0.00% 0.00% Compare
PTN Palatin Technologies, Inc. $11.6M — (loss-making) 0.2× −14.06% (below 0%: shrinking) n/m +34.21% (above 0%: growing) 100.00% (1,469.35%) Compare
CLRB Cellectar Biosciences, Inc. $11.2M — (loss-making) — −73.23% (below 0%: shrinking) n/m −17.49% (below 0%: shrinking) 0.00% 0.00% Compare
Median of peers $11.8M — — −15.83% — −11.51% 0.00% 0.00%

All 614 Biotechnology stocks →

Ensysce Biosciences, Inc. (ENSC) key facts

  • Concern: Ensysce Biosciences, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $5.1 million, down 2.75% from fiscal 2024.
  • Ensysce Biosciences, Inc. (ENSC) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, ENSC traded at $0.52, a market capitalization of $11.6 million.
  • Return on equity was −324.9% and debt-to-equity 0.00.
  • Its Piotroski F-score is 3 out of 9 and its Altman Z-score is −29.36 (distress zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

Ensysce Biosciences, Inc. (ENSC) Latest News

stockrow.com/ENSC · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com