Saturday 17 October 2026
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Caribou Biosciences, Inc.
CRBU Healthcare Biotechnology
Caribou Biosciences, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $11.2 million, up 11.7% from fiscal 2024. In the quarter to June 2026, revenue fell 43.8%, EPS grew 58.6% and free cash flow fell 33.2%, each against the same quarter a year earlier.
0.47
0.00
0.00%
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Target Price Range
Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Trend | 2026e | 2027e | 2028e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Price, $ | |||||||||||||||
| Price, $ | Low | — | — | — | — | — | 14.17 | 4.89 | 3.44 | 1.50 | 0.66 |
Analyst estimates 2026–2028 Powerpack |
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| High | — | — | — | — | — | 32.65 | 15.85 | 8.59 | 8.33 | 3.54 | |||||
| People | |||||||||||||||
| People | Employees | — | — | — | — | — | 97 | 137 | 158 | 147 | 97 | ||||
| Revenue/emp, $m | — | — | — | 0.00 | 0.00 | 0.10 | 0.10 | 0.22 | 0.07 | 0.12 | |||||
| Income, $m | |||||||||||||||
| Income, $m | Revenue | — | — | — | 6 | 12 | 10 | 14 | 34 | 10 | 11 | ||||
| Gross margin, % | — | — | — | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | |||||
| EBT | — | — | — | (31) | (36) | (67) | (99) | (102) | (149) | (149) | |||||
| EBT margin, % | — | — | — | (535.04) | (292.27) | (693.92) | (717.28) | (295.49) | (1,492.04) | (1,332.33) | |||||
| Net income | — | 0 | — | (23) | (34) | (67) | (99) | (102) | (149) | (148) | |||||
| Depreciation | — | — | — | 1 | 1 | 1 | 1 | (1) | (1) | 3 | |||||
| Per share, $ | |||||||||||||||
| Per share, $ | Revenue | — | — | — | 0.69 | 1.45 | 0.30 | 0.23 | 0.47 | 0.11 | 0.12 | ||||
| Earnings | — | — | — | (2.80) | (4.01) | (2.11) | (1.64) | (1.38) | (1.65) | (1.59) | |||||
| Cash flow | — | — | — | (3.82) | (3.89) | (1.03) | (1.50) | (1.26) | (1.53) | (1.19) | |||||
| Capex | — | — | — | (0.11) | (0.04) | (0.07) | (0.11) | (0.16) | (0.05) | (0.01) | |||||
| Free cash flow | — | — | — | (3.93) | (3.92) | (1.09) | (1.60) | (1.42) | (1.58) | (1.20) | |||||
| Book value | — | — | — | 0.00 | 2.09 | 12.25 | 4.95 | 4.99 | 2.80 | 1.31 | |||||
| Shares, m | — | — | — | 8 | 9 | 32 | 61 | 74 | 90 | 93 | |||||
| Valuation, × | |||||||||||||||
| Valuation, × | P/E | — | — | — | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||
| P/S | — | — | — | 13.15 | 13.15 | 49.78 | 29.02 | 11.92 | 14.37 | 13.31 | |||||
| P/B | — | — | — | 0.00 | 0.00 | 1.23 | 1.34 | 1.12 | 0.57 | 1.22 | |||||
| EV/Sales | — | — | — | 2.98 | 2.98 | 10.62 | 11.14 | 2.39 | (6.60) | 0.82 | |||||
| EV/FCF | — | — | — | (2.82) | (2.82) | (2.94) | (1.58) | (0.78) | 0.46 | (0.08) | |||||
| Cash, $m | |||||||||||||||
| Cash, $m | Operating cash flow | — | — | — | (32) | (33) | (33) | (91) | (93) | (138) | (111) | ||||
| Capex | — | — | — | (1) | 0 | (2) | (6) | (12) | (5) | (1) | |||||
| Free cash flow | — | — | — | (33) | (34) | (35) | (97) | (105) | (143) | (112) | |||||
| Balance, $m | |||||||||||||||
| Balance, $m | Working capital | — | — | — | 47 | 12 | 365 | 232 | 311 | 189 | 120 | ||||
| Total debt | — | — | — | 42 | 43 | 0 | 28 | — | — | — | |||||
| Net debt | — | — | — | (41) | (16) | (376) | (248) | (329) | (210) | (139) | |||||
| Shareholders’ equity | — | — | — | — | 18 | 388 | 301 | 368 | 253 | 122 | |||||
| Returns, % | |||||||||||||||
| Returns, % | ROA | — | — | — | 0.00 | (190.36) | (27.98) | (24.36) | (25.33) | (40.00) | (60.62) | ||||
| ROIC | — | — | — | 0.00 | (1,168.00) | (349.05) | (124.98) | (183.29) | (239.87) | 0.00 | |||||
| ROE | — | — | — | 293.36 | 429.55 | (36.73) | (28.87) | (30.50) | (47.99) | (78.97) | |||||
Negative figures in brackets.
Fiscal years to Dec 2025 · latest quarter Jun 2026
Charts ten years each
Caribou Biosciences, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| INKT MiNK Therapeutics, Inc. | $50.7M | — (loss-making) | — | — | n/m | −32.73% (below 0%: shrinking) | 0.00% | 0.00% | Compare |
| LONA LeonaBio, Inc. | $49.8M | — (loss-making) | — | — | n/m | −142.29% (below 0%: shrinking) | 0.00% | 0.00% | Compare |
| CRBU Caribou Biosciences, Inc. | $49.8M | — (loss-making) | — (loss-making) | −43.79% (below 0%: shrinking) | n/m | −33.16% (below 0%: shrinking) | 100.00% | (1,690.39%) | |
| MREO Mereo BioPharma Group plc - Sponsored ADR | $49.3M | — (loss-making) | — (loss-making) | — | n/m | +21.02% (above 0%: growing) | 0.00% | 0.00% | Compare |
| HYPD Hyperion DeFi, Inc. | $49.0M | — (loss-making) | 3.6× | +2,333.33% (above 0%: growing) | n/m | +86.82% (above 0%: growing) | 100.00% | 8,668.63% | Compare |
| HOWL Werewolf Therapeutics, Inc. | $48.5M | — (loss-making) | — (loss-making) | +256.11% (above 0%: growing) | n/m | +146.46% (above 0%: growing) | 100.00% | 34.09% | Compare |
| ELTX Elicio Therapeutics, Inc. | $48.2M | — (loss-making) | — (loss-making) | −55.27% (below 0%: shrinking) | n/m | +8.77% (above 0%: growing) | 0.00% | 0.00% | Compare |
| ACET Adicet Bio, Inc. | $48.1M | — (loss-making) | — (loss-making) | +727.73% (above 0%: growing) | n/m | +24.94% (above 0%: growing) | 0.00% | 0.00% | Compare |
| KLRS Kalaris Therapeutics Inc. | $47.8M | — (loss-making) | — | — | n/m | +11.91% (above 0%: growing) | 0.00% | 0.00% | Compare |
| Median of peers | $48.7M | — | — | +491.92% | — | +16.47% | 0.00% | 0.00% |
Caribou Biosciences, Inc. (CRBU) key facts
- Strength: Caribou Biosciences, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $11.2 million, up 11.7% from fiscal 2024.
- Caribou Biosciences, Inc. (CRBU) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
- As of October 16, 2026, CRBU traded at $0.47, a market capitalization of $49.8 million.
- Return on equity was −79.0% and debt-to-equity 0.00.
- Its Piotroski F-score is 3 out of 9 and its Altman Z-score is −5.00 (distress zone) for fiscal 2025.