Caribou Biosciences, Inc.

CRBU Healthcare Biotechnology

Caribou Biosciences, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $11.2 million, up 11.7% from fiscal 2024.

Revenue
−26.9%
EPS
+16.7%
Free cash flow
+84.8%

Quarter to September 2026, against a year earlier

0.44 0.03 +7.32%
Market cap
$44.2M
P/E
0.0×
Fwd P/E
−0.4×
Dividend yield
—
F-score
3/9
Altman Z
−5.00
Beneish M
−3.93
Dividend safety
n/a

Insider Decisions last twelve months

Sold, $m 0.05
Trades a month
Jan 26 Apr 26 Jul 26 Oct 26
Buy — — — — — — — — — — — —
Sell — — 5 — — — — — — — — —
Insider Ownership 9.28%

Capital & Financial Ratios $m

Size
Market Cap 44.20
Revenue ttm 9.44
Net income ttm (102.47)
Free cash flow ttm (93.11)
Net debt Q (94.80)
Valuation
P/E 0.00
Forward P/E (0.43) (negative: loss-making)
Price / sales 5.01
Forward P/S Powerpack
Price / FCF 0.00
Price / book 0.62
Financial health
Current ratio Q 4.97 (at or above 1.5: strong)
Debt / equity Q 0.00 (at or below 0.5: strong)
Interest coverage Q (83.08)
Growth
Revenue growth Q −26.89% (below 0%: shrinking)
Operating income growth Q +5.98% (above 0%: growing)
EPS, this year +43.90% (at or above 15%: strong)
EPS, next year A −22.42% (below 0%: weak)
Revenue, next year A +114.71% (at or above 10%: strong)
EPS, past 5 yrs —
EPS, next 5 yrs A −2.05% (below 0%: weak)

Green and red mark values outside typical ranges; (Q) is the latest quarter, (A) analysts’ estimates. How we judge →

Valuation vs history

P/S against its own 10 years 1.88%
10-year low 10-year high
P/B against its own 10 years 16.22%
10-year low 10-year high

Dividends

Yield
—
Annual rate
—
Payout ratio
—

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 329 210 139 95
Receivables 2 2 2 —
Inventory — — — —
Other 1 1 1 1
339 219 145 100
2023 2024 2025 Q'26
Payables 3 2 6 5
ST’ Debt — — — —
Other — — — —
28 31 25 20

Compound Annual Growth %

10y 5y 3y
Sales — (2.03%) (6.95%)
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 46.86% (25.95%)

Earnings Trends EPS, adjusted, against the consensus

EPS $

Mar Jun Sep Dec Year
’26 (0.26) (0.24) (0.25) — —
’25 (0.43) (0.58) (0.30) (0.28) (1.59)
’24 (0.46) (0.42) (0.38) (0.39) (1.65)
’23 (0.46) (0.48) (0.12) (0.39) (1.38)
’22 (0.32) (0.44) (0.44) (0.44) (1.64)
’21 (1.39) (1.39) (0.46) (0.31) (2.11)
’20 (0.16) (0.22) (0.93) — (4.01)
Fiscal quarters ending in the months shown.

Revenue $m

Mar Jun Sep Dec Year
’26 2 1 2 — —
’25 2 3 2 4 11
’24 2 3 2 2 10
’23 4 4 24 4 34
’22 3 4 3 4 14
’21 2 1 4 3 10
’20 2 8 1 — 12
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (27) (23) (23) — —
’25 (37) (28) (25) (21) (111)
’24 (37) (33) (33) (35) (138)
’23 (28) (15) (29) (21) (93)
’22 (22) (22) (22) (25) (91)
’21 20 (16) (15) (21) (33)
’20 (9) (16) (9) (8) (33)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (27) 63 (23) — —
’25 (38) 94 (148) (21) (112)
’24 (39) (35) (33) (36) (143)
’23 (30) (18) (34) (24) (105)
’22 (22) (24) (24) (27) (97)
’21 20 (17) (16) (22) (35)
’20 (9) (17) (9) (8) (34)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

2
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Ten-year view Analyst estimates Powerpack
Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 TTM Sep ’26 Trend 10 yrs 2026e 2027e 2028e Next 3/yr
Income, $m
Income, $m Revenue — — — 6 12 10 14 34 10 11 9 +11.6% 24 23 31 +40.4%
Gross margin, % — — — 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 0.0 pt
EBT — — — (31) (36) (67) (99) (102) (149) (149) (103) +29.9%
EBT margin, % — — — (535.04) (292.27) (693.92) (717.28) (295.49) (1,492.04) (1,332.33) (1,090.82) (797.3) pt
Net income — 0 — (23) (34) (67) (99) (102) (149) (148) (102) n/m
Per share, $
Per share, $ Revenue — — — 0.69 1.45 0.30 0.23 0.47 0.11 0.12 0.09 (25.4%)
Earnings — — — (2.80) (4.01) (2.11) (1.64) (1.38) (1.65) (1.59) (1.03) (9.0%)
Cash flow — — — (3.82) (3.89) (1.03) (1.50) (1.26) (1.53) (1.19) (0.87) (17.7%)
Capex — — — (0.11) (0.04) (0.07) (0.11) (0.16) (0.05) (0.01) 0.00 (28.1%)
Free cash flow — — — (3.93) (3.92) (1.09) (1.60) (1.42) (1.58) (1.20) (0.87) (17.9%)
Book value — — — 0.00 2.09 12.25 4.95 4.99 2.80 1.31 0.71 n/m
Shares, m — — — 8 9 32 61 74 90 93 99 +49.5%
Valuation, ×
Valuation, × P/E — — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.0
P/S — — — 13.15 13.15 49.78 29.02 11.92 14.37 13.31 5.01 20.7
P/B — — — 0.00 0.00 1.23 1.34 1.12 0.57 1.22 0.62 0.8
EV/Sales — — — 2.98 2.98 10.62 11.14 2.39 (6.60) 0.82 (5.03) 3.5
EV/FCF — — — (2.82) (2.82) (2.94) (1.58) (0.78) 0.46 (0.08) 0.36 (1.5)
Cash, $m
Cash, $m Operating cash flow — — — (32) (33) (33) (91) (93) (138) (111) (93) +23.0%
Capex — — — (1) 0 (2) (6) (12) (5) (1) (37) +7.4%
Free cash flow — — — (33) (34) (35) (97) (105) (143) (112) (93) +22.7%
Balance, $m
Balance, $m Working capital — — — 47 12 365 232 311 189 120 80 +16.9%
Net debt — — — (41) (16) (376) (248) (329) (210) (139) (95) +22.6%
Shareholders’ equity — — — — 18 388 301 368 253 122 77 +46.9%
Returns, %
Returns, % ROA — — — 0.00 (190.36) (27.98) (24.36) (25.33) (40.00) (60.62) (64.44) (60.6) pt
ROIC — — — 0.00 (1,168.00) (349.05) (124.98) (183.29) (239.87) 0.00 0.00 0.0 pt
ROE — — — 293.36 429.55 (36.73) (28.87) (30.50) (47.99) (78.97) (93.80) (372.3) pt
People
People Employees — — — — — 97 137 158 147 97 — 0.0%
Revenue/emp, $m — — — 0.00 0.00 0.10 0.10 0.22 0.07 0.12 — n/m
Negative figures in brackets.
estimates

All 10 years →

Fiscal years to Dec 2025 · latest quarter Sep 2026 · fundamentals updated 5 Nov 2026

Caribou Biosciences, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
CNTB Connect Biopharma Holdings Limited Sponsored ADR $46.1M — (loss-making) — (loss-making) +296.56% (above 0%: growing) n/m −23.48% (below 0%: shrinking) 100.00% (635.98%) Compare
MREO Mereo BioPharma Group plc - Sponsored ADR $44.8M — (loss-making) — (loss-making) — n/m +21.02% (above 0%: growing) 0.00% 0.00% Compare
IBIO iBio, Inc. $44.4M — (loss-making) — (loss-making) +100.00% (above 0%: growing) n/m −35.33% (below 0%: shrinking) 100.00% 0.00% Compare
CRBU Caribou Biosciences, Inc. $44.2M — (loss-making) — (loss-making) −26.89% (below 0%: shrinking) n/m +84.78% (above 0%: growing) 100.00% (1,720.10%)
BMEA Biomea Fusion, Inc. $42.6M — (loss-making) — — n/m +47.80% (above 0%: growing) 0.00% 0.00% Compare
ATHE Alterity Therapeutics Limited - Sponsored ADR $42.4M — (loss-making) — — 0.00% −84.83% (below 0%: shrinking) 0.00% — Compare
GANX Gain Therapeutics, Inc. $41.9M — (loss-making) — (loss-making) +27.78% (above 0%: growing) n/m +8.22% (above 0%: growing) 0.00% 0.00% Compare
SER Serina Therapeutics, Inc. $41.9M — (loss-making) — (loss-making) +2,500.00% (above 0%: growing) n/m −76.82% (below 0%: shrinking) 100.00% 0.00% Compare
SGMOQ Sangamo Therapeutics, Inc. $41.9M — (loss-making) — (loss-making) −77.60% (below 0%: shrinking) n/m +26.21% (above 0%: growing) 100.00% (2,215.40%) Compare
Median of peers $42.5M — — +100.00% — −7.63% 50.00% 0.00%

All 621 Biotechnology stocks →

Pay and ownership Proxy statement filed 24 April 2026

Ownership

Directors and executive officers, together 8.54%
Rachel Haurwitz, Ph.D. 5.28%
Ownership is the proxy’s own table: the directors and officers as a group, and every holder of 5% or more. Read the proxy statement

Caribou Biosciences, Inc. (CRBU) Latest News

5 Nov

8 Oct

6 Oct

10 Feb

Impact 4 · · Simply Wall St.

13 Jan

8 Jan

Impact 4 · · Simply Wall St.
stockrow.com/CRBU · Data as of Nov 5, 2026 · For information only; not investment advice. · © 2026 stockrow.com