Caribou Biosciences, Inc. CRBU

1.24 (0.01) (0.80%) as of 25 Sep
Market cap
$134.0M
P/E
0.0×

Insider Decisions

Total sells 0.05
in millions of $
Nov 25 Feb 26 May 26 Aug 26
Buy — — — — — — — — — — — —
Sell — — — — 5 — — — — — — —
Insider Ownership 3.39%

Capital & Financial Ratios

Market Cap 134.01
Revenue 10.04
Net Income (103.40)
Free Cash Flow (132.79)
Net Debt (112.31)
Current Ratio 6.49
Debt/Equity 0.00
P/E ratio 0.00
P/S ratio 12.58
P/B ratio 1.29
Past 5Y EPS Growth (33.41%)
This Y EPS Growth 40.41%
Next Y EPS Growth (35.62%)
Next 5Y EPS Growth (2.05%)
in millions of $

Dividends

Payout Ratio 0.00
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
predictions in italic, special payouts not included in total or ratios

Assets vs Liabilities

2023 2024 2025 Q'26
Cash 329 210 139 112
Receivables 2 2 2 1
Inventory — — — —
Other 1 1 1 1
339 219 145 117
2023 2024 2025 Q'26
Payables 3 2 6 3
ST’ Debt — — — —
Other — — — —
28 31 25 18
in millions of $

Compound Annual Growth

10y 5y 3y
Sales — (2.03%) (6.95%)
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 46.86% (25.95%)

Revenue

Mar Jun Sep Dec Year
’26 2 1 — — —
’25 2 3 2 4 11
’24 2 3 2 2 10
’23 4 4 24 4 34
’22 3 4 3 4 14
’21 2 1 4 3 10
’20 2 8 1 — 12
in millions of $ · fiscal quarters ending in the months shown

Operating Cash Flow

Mar Jun Sep Dec Year
’26 (27) (23) — — —
’25 (37) (28) (25) (21) (111)
’24 (37) (33) (33) (35) (138)
’23 (28) (15) (29) (21) (93)
’22 (22) (22) (22) (25) (91)
’21 20 (16) (15) (21) (33)
’20 (9) (16) (9) (8) (33)
in millions of $ · fiscal quarters ending in the months shown

Free Cash Flow

Mar Jun Sep Dec Year
’26 (27) 63 — — —
’25 (38) 94 (148) (21) (112)
’24 (39) (35) (33) (36) (143)
’23 (30) (18) (34) (24) (105)
’22 (22) (24) (24) (27) (97)
’21 20 (17) (16) (22) (35)
’20 (9) (17) (9) (8) (34)
in millions of $ · fiscal quarters ending in the months shown

EPS

Mar Jun Sep Dec Year
’26 (0.26) (0.24) — — —
’25 (0.43) (0.58) (0.30) (0.28) (1.59)
’24 (0.46) (0.42) (0.38) (0.39) (1.65)
’23 (0.46) (0.48) (0.12) (0.39) (1.38)
’22 (0.32) (0.44) (0.44) (0.44) (1.64)
’21 (1.39) (1.39) (0.46) (0.31) (2.11)
’20 (0.16) (0.22) (0.93) — (4.01)
fiscal quarters ending in the months shown

Target Price Range

Analyst price targets

Recommendation Rating

1
1Buy 2 3Hold 4 5Sell
2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028
— — — — — 14.17 4.89 3.44 1.50 0.66

Analyst estimates 2026–2028

Powerpack
Low Price
— — — — — 32.65 15.85 8.59 8.33 3.54
High Price
— — — — — 97 137 158 147 97
Employees
— — — 0 0 0 0 0 0 0
Revenue/Emp
— — — 6 12 10 14 34 10 11
Revenue
— — — 100.00% 100.00% 100.00% 100.00% 100.00% 100.00% 100.00%
Gross Margin
— — — (31) (36) (67) (99) (102) (149) (149)
EBT
— — — (535.04%) (292.27%) (693.92%) (717.28%) (295.49%) (1,492.04%) (1,332.33%)
EBT Margin
— 0 — (23) (34) (67) (99) (102) (149) (148)
Net Income
— — — 1 1 1 1 (1) (1) 3
Depreciation
— — — 0.69 1.45 0.30 0.23 0.47 0.11 0.12
Revenue/Sh
— — — (2.80) (4.01) (2.11) (1.64) (1.38) (1.65) (1.59)
Earnings/Sh
— — — (3.82) (3.89) (1.03) (1.50) (1.26) (1.53) (1.19)
Cash Flow/Sh
— — — (0.11) (0.04) (0.07) (0.11) (0.16) (0.05) (0.01)
Capex/Sh
— — — (3.93) (3.92) (1.09) (1.60) (1.42) (1.58) (1.20)
Free CF/Sh
— — — 0.00 2.09 12.25 4.95 4.99 2.80 1.31
Book Value/Sh
— — — 8 9 32 61 74 90 93
Shares
— — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00
PE Ratio
— — — 13.15 13.15 49.78 29.02 11.92 14.37 13.31
PS Ratio
— — — 0.00 0.00 1.23 1.34 1.12 0.57 1.22
PB Ratio
— — — 2.98 2.98 10.62 11.14 2.39 (6.60) 0.82
EV/Sales
— — — (2.82) (2.82) (2.94) (1.58) (0.78) 0.46 (0.08)
EV/FCF
— — — (32) (33) (33) (91) (93) (138) (111)
Op' Cash Flow
— — — (1) 0 (2) (6) (12) (5) (1)
Capex
— — — (33) (34) (35) (97) (105) (143) (112)
FCF
— — — 47 12 365 232 311 189 120
Working Cap'
— — — 42 43 0 28 — — —
Total Debt
— — — (41) (16) (376) (248) (329) (210) (139)
Net Debt
— — — 0 18 388 301 368 253 122
Sh' Equity
— — — 0.00% (190.36%) (27.98%) (24.36%) (25.33%) (40.00%) (60.62%)
ROA
— — — 0.00% (1,168.00%) (349.05%) (124.98%) (183.29%) (239.87%) 0.00%
ROIC
— — — 293.36% 429.55% (36.73%) (28.87%) (30.50%) (47.99%) (78.97%)
ROE
predictions in italic, sparklines do not include predictions

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Caribou Biosciences, Inc. (CRBU) key facts

  • Caribou Biosciences, Inc. (CRBU) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • Caribou Biosciences, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $11.2 million, up 11.7% from fiscal 2024.
  • As of September 25, 2026, CRBU traded at $1.24, a market capitalization of $134.0 million.
  • Return on equity was −79.0% and debt-to-equity 0.00.

Source: company filings (standardised) and stockrow calculations.

Caribou Biosciences, Inc. (CRBU) Latest News

News by impact score

Fine-tune

13 Aug

3

Caribou Biosciences reported a Q2 loss and missed revenue estimates. Q2 loss combined with missed revenue estimates signals weaker financial results that can affect near-term investor sentiment.

3

Caribou Biosciences reported second quarter 2026 financial results and provided a business update. Quarterly results and updates supply performance data that can shift near-term investor views without guaranteeing major trajectory changes.

11 Jun

4

Caribou Biosciences reported long-term Vispa-cel data in second-line large B cell lymphoma at EHA 2026. Long-term clinical data on core pipeline candidate Vispa-cel can materially shift company valuation and trajectory.

3

Caribou Biosciences reported dose escalation durability data for CB-011 at the 2026 European Hematology Association Annual Meeting. CB-011 durability data at EHA indicates pipeline progress that may affect near-term valuation.

9 Jun

4

Caribou Biosciences states its CRISPR CAR-T therapy is pivotal-ready with CB-011 data approaching. Pivotal readiness for lead CRISPR CAR-T program advances company toward late-stage trials and potential commercialization.

31 May

3

Caribou Biosciences (CRBU) receives a higher price target as analyst confidence grows in the company's pipeline. Raised price target signals stronger market confidence in CRBU pipeline progress that may lift near-term stock performance.

13 May

4

Industry analysts have massively upgraded revenue forecasts for Caribou Biosciences, Inc. (NASDAQ:CRBU), signaling strong expected growth. Massive upgrades to revenue forecasts by analysts are likely to drive significant positive shifts in investor sentiment and CRBU's market performance.

12 May

4

Caribou Biosciences will deliver oral presentations highlighting its Vispa-cel and CB-011 programs at the 2026 European Hematology Association Annual Meeting. Oral presentations at a premier hematology conference on lead CAR-T programs like Vispa-cel and CB-011 will boost visibility, validate progress, and likely enhance investor sentiment and stock performance.

7 May

3

Caribou Biosciences, Inc. (CRBU) reported a first-quarter loss and missed revenue estimates. Q1 loss and revenue miss will noticeably affect financial performance and market sentiment but not fundamentally alter long-term biotech trajectory.

3

Caribou Biosciences reported first quarter 2026 financial results and provided a business update. Quarterly financial results and business updates for a clinical-stage biotech like CRBU typically influence financial performance and investor sentiment through pipeline progress and cash runway details.

31 Mar

4

FDA granted Regenerative Medicine Advanced Therapy (RMAT) designation to Caribou Biosciences' CB-011, an allogeneic anti-BCMA CAR-T cell therapy for multiple myeloma. RMAT designation accelerates CB-011's development, review, and potential approval, significantly boosting CRBU's pipeline value and investor sentiment.

14 Mar

4

Caribou Biosciences announced plans for a Phase 3 trial of vispa-cel in large B-cell lymphoma (LBCL) and will pursue financing at the Leerink Conference. Phase 3 advancement for vispa-cel and financing pursuit mark major strategic steps that could significantly enhance pipeline value and attract investment.

5 Mar

3

Caribou Biosciences, Inc. (CRBU) reported a Q4 net loss but exceeded revenue estimates. Q4 loss despite revenue beat highlights mixed financial results likely to moderately influence stock sentiment and near-term performance.

3

Caribou Biosciences (CRBU) reported fourth quarter and full year 2025 financial results and provided a business update. Quarterly and annual financial results with business updates typically influence financial performance and market sentiment moderately.

23 Feb

4

Caribou Biosciences detailed pivotal-ready plans for its allogeneic CAR-T therapy Vispa-cel at the Citi Summit, including manufacturing readiness and trial designs, while flagging the need for additional capital to advance development. Pivotal-ready Vispa-cel advances core CAR-T pipeline toward key trials, driving positive investor sentiment despite capital raise signaling dilution risks.

20 Feb

3

Clear Street predicts Caribou Biosciences' CB-011 could hit $734 million in peak sales by 2040. Analyst forecast of $734 million peak sales for CB-011 by 2040 signals moderate long-term revenue potential and investor interest in CRBU's pipeline.

17 Feb

3

Watchmaker Genomics licensed CRISPR-Cas9 intellectual property from Caribou Biosciences to enhance throughput and reduce sequencing costs per sample. Licensing core CRISPR-Cas9 IP generates potential royalties and validates technology, providing moderate financial and strategic benefits.

10 Feb

4

Caribou Biosciences, Inc. (CRBU) is highlighted as a promising penny stock for February 2026, showcasing its potential in the biotech sector. The company is recognized for its innovative CRISPR technology, which is expected to drive advancements in gene editing and therapeutic applications. Investors are encouraged to consider CRBU for its growth prospects amid a competitive landscape. The article emphasizes the importance of monitoring market trends and the company's strategic initiatives as key factors influencing its future performance. The company's innovative CRISPR technology and potential advancements in gene editing could significantly alter its market position and investor sentiment.

4 Feb

4

Caribou Biosciences, Inc. announced late-breaking presentations at the 2026 Tandem Meetings of ASTCT® and CIBMTR®. These presentations will highlight the company's advancements in gene editing and its potential applications in cell therapies, showcasing its commitment to innovation in the biotechnology sector. The presentations are expected to significantly influence investor sentiment and highlight key advancements in the company's technology.

13 Jan

4

Caribou Biosciences, Inc. (CRBU) has been upgraded to a 'Buy' rating by analysts due to its promising advancements in CRISPR technology and potential for significant growth in the biotech sector. The company's recent developments in gene editing and partnerships with major pharmaceutical firms have positioned it favorably in the market. Analysts believe that these factors, combined with a strong pipeline of therapies, will enhance CRBU's financial performance and investor appeal in the coming years. The upgrade reflects significant advancements and partnerships that could substantially influence Caribou's market position and growth trajectory.

8 Jan

4

Caribou Biosciences, Inc. (CRBU) is highlighted as a promising penny stock for January 2026, showcasing its advancements in CRISPR technology and potential applications in various therapeutic areas. The company is noted for its innovative approach to gene editing, which positions it favorably in the biotech sector. Investors are encouraged to consider CRBU as part of their portfolio due to its growth prospects and the increasing interest in gene therapies. Significant advancements in CRISPR technology and potential therapeutic applications could greatly influence the company's market position and investor sentiment.

5 Dec

3

Caribou Biosciences, Inc. (CRBU) is highlighted among promising penny stocks, showcasing its potential in the biotech sector. The company focuses on CRISPR technology for cell therapies, which could revolutionize treatments for various diseases. Investors are encouraged to consider CRBU alongside other stocks for potential growth opportunities in the market. Caribou's focus on innovative CRISPR technology may moderately influence its competitive positioning and market performance.

1 Dec

4

Caribou Biosciences, Inc. will host an in-person and virtual Key Opinion Leader (KOL) event at the American Society of Hematology (ASH) 2025 conference. The event aims to showcase the company's advancements in gene editing and its potential applications in hematological diseases. Attendees will include leading experts in the field, providing insights into Caribou's innovative approaches and future directions. The event is likely to significantly enhance Caribou's visibility and credibility in the market, potentially impacting investor sentiment and strategic partnerships.

12 Nov

3

Caribou Biosciences, Inc. (CRBU) reported a loss for Q3, falling short of revenue estimates. The company's financial performance has raised concerns among investors, as it continues to navigate challenges in its operational landscape. Despite the setback, Caribou remains focused on its strategic initiatives and product development efforts. The missed revenue estimates indicate potential challenges in financial performance, which may affect investor sentiment and operational focus.

3

Caribou Biosciences, Inc. (CRBU) reported its financial results for the third quarter of 2025, highlighting key metrics and developments in its business operations. The company provided updates on its ongoing projects and strategic initiatives, indicating progress in its research and development efforts. Financial performance showed trends that may influence future growth and investor sentiment. The financial results and business updates indicate moderate influence on the company's future performance and market positioning.

6 Nov

3

Caribou Biosciences, Inc. (CRBU) experienced a 7.8% decline in stock price despite announcing positive Phase 1 CAR-T data and plans for a Phase 3 trial. Investors are questioning whether the bullish outlook for the company has changed following these developments. Positive Phase 1 data and Phase 3 plans indicate potential for future growth, but the stock drop suggests investor skepticism.

4 Nov

4

Caribou Biosciences, Inc. (CRBU) has made progress with its CB-011 CAR-T therapy, showing promising early data that could enhance its valuation. The company is advancing its pipeline, which includes multiple CAR-T therapies aimed at treating various cancers. Analysts are closely monitoring these developments as they could significantly influence the company's market position and investor sentiment moving forward. Promising early data and pipeline advancements are likely to significantly impact the company's future performance and market perception.

3 Nov

4

Caribou Biosciences, Inc. announced positive results from its ANTLER Phase 1 trial for Vispa-cel (CB-010), an allogeneic CAR-T cell therapy. The data demonstrated efficacy and durability comparable to autologous CAR-T cell therapies, suggesting a promising alternative in cancer treatment. This advancement could enhance the company's position in the competitive CAR-T market. Positive trial results indicate significant potential for Vispa-cel to impact market positioning and investor sentiment.

4

Caribou Biosciences, Inc. announced positive results from its Phase 1 CaMMouflage trial of CB-011, a treatment for multiple myeloma. The trial demonstrated promising safety and efficacy outcomes, with a notable reduction in tumor burden among participants. These findings support the potential of CB-011 as a viable therapeutic option for patients with this challenging cancer. The company plans to advance the development of CB-011 based on these encouraging results. Positive trial results could significantly enhance Caribou's competitive position and investor sentiment in the oncology market.

3

Caribou Biosciences, Inc. (CRBU) has been highlighted as one of the most active stocks in the market. The company is involved in the development of innovative CRISPR-based therapies, which are gaining attention due to their potential in treating various diseases. Investors are closely monitoring CRBU's progress and market movements, reflecting heightened interest in biotechnology stocks. Increased market activity and investor interest may moderately influence Caribou's financial performance and competitive positioning.

stockrow.com/CRBU · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com