LeonaBio, Inc. LONA
- Market cap
- $54.3M
- P/E
- 0.0×
Follow LONA
Target Price Range
Analyst price targets
Free account| 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | 2026 | 2027 | 2028 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| — | — | — | — | 157.90 | 88.80 | 25.30 | 13.30 | 4.12 | 2.20 |
Analyst estimates 2026–2028 Powerpack |
Low Price
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| — | — | — | — | 347.90 | 342.50 | 142.20 | 44.10 | 42.98 | 8.36 |
High Price
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| — | — | — | — | 22 | 35 | 64 | 67 | 26 | 19 |
Employees
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| — | — | — | — | 0 | 0 | 0 | 0 | 0 | 0 |
Revenue/Emp
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| — | — | — | — | — | — | — | — | — | — | Revenue | |||
| — | — | — | — | 0.00% | 0.00% | 0.00% | — | — | — |
Gross Margin
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| — | — | (5) | (5) | (20) | (55) | (96) | (118) | (97) | (106) |
EBT
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| — | — | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
EBT Margin
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| — | 0 | (5) | (5) | (20) | (55) | (96) | (118) | (97) | (106) |
Net Income
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| — | — | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
Depreciation
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| — | — | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
Revenue/Sh
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| — | — | (14.69) | (14.47) | (16.70) | (14.90) | (25.30) | (30.90) | (25.20) | (24.70) |
Earnings/Sh
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| — | — | (12.92) | (10.41) | (20.15) | (11.67) | (19.21) | (26.50) | (25.25) | (10.69) |
Cash Flow/Sh
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| — | — | 0.00 | 0.00 | (1.94) | (0.43) | (0.30) | (0.08) | (0.01) | 0.00 |
Capex/Sh
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| — | — | (12.92) | (10.41) | (22.09) | (12.10) | (19.51) | (26.58) | (25.26) | (10.69) |
Free CF/Sh
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| — | — | 6.24 | (7.49) | 229.20 | 86.97 | 62.32 | 34.24 | 11.65 | 6.50 |
Book Value/Sh
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| — | — | 0 | 0 | 1 | 4 | 4 | 4 | 4 | 4 |
Shares
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| — | — | — | — | — | — | — | — | — | — | PE Ratio | |||
| — | — | — | — | — | — | — | — | — | — | PS Ratio | |||
| — | — | — | — | — | — | — | — | — | — | PB Ratio | |||
| — | — | — | — | — | — | — | — | — | — | EV/Sales | |||
| — | — | — | — | — | — | — | — | — | — | EV/FCF | |||
| — | — | (4) | (4) | (24) | (43) | (72) | (101) | (97) | (46) |
Op' Cash Flow
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| — | — | — | — | (2) | (2) | (1) | 0 | 0 | — |
Capex
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| — | — | (4) | (4) | (26) | (45) | (74) | (101) | (97) | (46) |
FCF
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| — | — | 4 | 1 | 188 | 252 | 186 | 126 | 42 | 42 |
Working Cap'
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| — | — | 1 | 2 | 1 | 2 | 2 | — | — | — |
Total Debt
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| — | — | (4) | (1) | (184) | (252) | (199) | (147) | (51) | (88) |
Net Debt
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| — | — | 2 | (3) | 274 | 321 | 235 | 130 | 45 | 28 |
Sh' Equity
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| — | — | (206.65%) | (144.93%) | (14.16%) | (17.94%) | (32.41%) | (56.25%) | (88.52%) | (139.94%) |
ROA
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| — | — | 0.00% | 0.00% | (13.81%) | (58.03%) | (178.71%) | 0.00% | 0.00% | 0.00% |
ROIC
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| — | — | 29.45% | 29.82% | (15.68%) | (18.43%) | (34.39%) | (64.42%) | (110.77%) | (290.81%) |
ROE
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LeonaBio, Inc. peers in Biotechnology
| Company | Market cap | P/E | Compare |
|---|---|---|---|
| SER Serina Therapeutics, Inc. | $54.4M | 0.0× | Compare |
| EDSA Edesa Biotech, Inc. | $54.5M | 0.0× | Compare |
| MREO Mereo BioPharma Group plc - Sponsored ADR | $54.9M | 0.0× | Compare |
| ELTX Elicio Therapeutics, Inc. | $53.4M | 0.0× | Compare |
| Company | Market cap | P/E | Compare |
|---|---|---|---|
| INMB INmune Bio, Inc. | $55.5M | 0.0× | Compare |
| IMA ImageneBio, Inc. | $52.9M | 0.0× | Compare |
| ANVS Annovis Bio, Inc. | $56.8M | 0.0× | Compare |
| HRTX Heron Therapeutics, Inc. | $57.0M | 0.0× | Compare |
LeonaBio, Inc. (LONA) key facts
- LeonaBio, Inc. (LONA) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
- LeonaBio, Inc. reported a net loss of $105.6 million, or a loss of $24.70 per share, for fiscal 2025.
- As of September 25, 2026, LONA traded at $3.25, a market capitalization of $54.3 million.
- Return on equity was −290.8% and debt-to-equity 0.00.
LeonaBio, Inc. (LONA) Latest News
17 Aug
LeonaBio beats Q2 loss forecast while advancing Phase 3 ELAINE-3 trial. Beating loss forecasts plus Phase 3 progress signals stronger financials and clinical momentum that can lift valuation and sentiment.
14 Aug
Athira Pharma, Inc. presented results from its Phase 1 trial of ATH-1105 at the ALS Nexus 2025 conference. The trial aimed to evaluate the safety and tolerability of ATH-1105 in patients with amyotrophic lateral sclerosis (ALS). Preliminary findings indicated a favorable safety profile and potential efficacy, prompting further investigation into the drug's therapeutic benefits. The presentation garnered attention from the scientific community, highlighting Athira's commitment to advancing treatments for neurodegenerative diseases. The Phase 1 trial results could significantly influence Athira's future product development and market positioning in the ALS treatment landscape.
LeonaBio, Inc. (LONA) released second quarter 2026 financial results and a business update. Quarterly earnings release supplies performance data that can shift near-term investor views and valuation.
12 Aug
LeonaBio will highlight Lasofoxifene for ER-positive, HER2-negative, ESR1-mutated metastatic breast cancer at DAVA Oncology’s 4th Summit on Breast Cancer. Lasofoxifene presentation at summit may moderately boost visibility for LeonaBio's targeted breast cancer therapy.
4 Jun
LeonaBio presented on ATH-1105 at the 5th Annual ALS Drug Development Summit. Presentation at ALS summit may raise visibility for ATH-1105 development program.
7 May
LeonaBio, Inc. (LONA) reported first quarter 2026 financial results and provided a business update. Quarterly financial results and business updates moderately influence financial performance and investor sentiment.
LeonaBio, Inc. (LONA) appointed Fred Callori, J.D., Natalie Holles, and Peter B. Silverman, J.D. to its Board of Directors. Board appointments of experienced individuals like Fred Callori, Natalie Holles, and Peter B. Silverman enhance governance and strategic positioning with moderate impact on future performance.
23 Apr
LeonaBio, Inc. (LONA) will host a virtual Key Opinion Leader event highlighting lasofoxifene's potential in treatment-resistant ER+/HER2-, ESR1-mutated metastatic breast cancer. KOL event on lasofoxifene targets high-unmet need in resistant breast cancer, likely influencing investor sentiment and competitive positioning without guaranteeing transformative outcomes.
21 Apr
Independent nonclinical research on Lasofoxifene presented at the American Association for Cancer Research Annual Meeting 2026 aligns with LeonaBio’s data. Independent validation at a major conference moderately bolsters LeonaBio's credibility and market sentiment for its oncology drug candidate.
26 Mar
LeonaBio, Inc. (LONA) reported full-year 2025 financial results and provided a business update. Full-year financial results and business updates often drive significant shifts in investor sentiment and stock valuation.
3 Feb
LeonaBio, Inc. has appointed Mark F. Kubik as Chief Business Officer. Kubik brings extensive experience in the biotechnology sector, having held leadership roles at various companies. His appointment is expected to enhance LeonaBio's strategic initiatives and business development efforts. The appointment of an experienced executive may positively influence the company's operations and market positioning.
9 Jan
Athira Pharma, Inc. has officially changed its name to LeonaBio, Inc., along with a new ticker symbol 'LONA'. This rebranding reflects the company's strategic shift and future direction. The name change and new ticker may influence market perception and branding but are not expected to fundamentally alter the company's trajectory.
18 Dec
Athira Pharma, Inc. has secured an exclusive license for the Phase 3 development program of lasofoxifene, a candidate for metastatic breast cancer. The agreement includes a financing arrangement that could total up to $236 million, aimed at advancing the clinical development of this promising therapeutic option. The exclusive licensing and significant financing for a Phase 3 program could substantially enhance Athira's product pipeline and market position.
Insiders at Athira Pharma, Inc. have been net buyers of shares in the past year, with Independent Chairwoman Kelly Romano making the largest purchase. Insider transactions may have a moderately noticeable influence on Athira Pharma's future performance.
6 Nov
Athira Pharma, Inc. reported its financial results for the third quarter of 2025, highlighting key metrics and developments in its business operations. The company provided updates on its ongoing clinical trials and strategic initiatives aimed at advancing its pipeline. Financial performance showed trends that may influence future growth, while management outlined plans for upcoming product launches and collaborations. The financial results and updates on clinical trials indicate a moderately noticeable influence on the company's future performance and market positioning.
11 Sep
Athira Pharma, Inc. announced a reverse stock split aimed at increasing the per-share price of its common stock. The split will be executed at a ratio of 1-for-15, effective on a date to be determined. This move is intended to help the company meet the minimum bid price requirement for continued listing on the Nasdaq. The reverse split will reduce the number of outstanding shares, which may positively influence market perception and investor interest. The reverse stock split is expected to have a moderate influence on market perception and investor interest, but its overall effect on the company's trajectory remains limited.
7 Aug
Athira Pharma, Inc. reported its financial results for the second quarter of 2025, highlighting key metrics and updates on its business operations. The company continues to advance its clinical programs and is focused on addressing neurodegenerative diseases. Financial performance showed progress, with increased revenue and reduced losses compared to previous quarters. Management provided insights into future strategies and ongoing research initiatives aimed at enhancing shareholder value. Financial results and updates on clinical programs indicate a moderately noticeable influence on the company's future performance.
14 May
Athira Pharma, Inc. announced it will present data from its first-in-human Phase 1 trial of ATH-1105, a novel therapeutic candidate aimed at treating neurodegenerative diseases. The trial's results are expected to provide insights into the safety and efficacy of ATH-1105, potentially advancing the company's pipeline in addressing critical unmet medical needs. The presentation of Phase 1 trial data for ATH-1105 could significantly influence investor sentiment and the company's future trajectory in the neurodegenerative disease market.
13 May
Athira Pharma, Inc. announced positive results from a Phase 1 clinical trial of ATH-1105, showing a favorable safety profile and pharmacokinetics in healthy volunteers. The company plans to initiate a clinical trial in ALS patients by late 2025. Data will be presented at the 4th Annual ALS Drug Development Summit, highlighting ATH-1105's potential as a treatment for neurodegenerative diseases, including ALS. The trial involved 80 healthy volunteers and demonstrated robust effects in preclinical models, supporting further development. Positive Phase 1 trial results and plans for ALS patient trials indicate significant potential for future product development and market impact.
9 May
Athira Pharma, Inc. reported its Q1 2025 financial results, highlighting the completion of a Phase 1 clinical study of ATH-1105 for ALS, with full data expected in 2H25. The company aims to start dosing ALS patients by late 2025. ATH-1105 has shown promising preclinical results and a favorable safety profile in healthy volunteers. Following disappointing results from its fosgonimeton trial for Alzheimer's, Athira is exploring strategic alternatives and has paused further development of fosgonimeton. As of March 31, 2025, Athira's cash position was $36.7 million, with a net loss of $9.1 million for the quarter. The advancement of ATH-1105 and the exploration of strategic alternatives following the fosgonimeton trial are significant moves that could alter the company's trajectory.
27 Feb
Athira Pharma, Inc. reported its full year 2024 financial results, highlighting advancements in its pipeline and business strategies. The company continues to focus on developing therapies for neurodegenerative diseases, with updates on clinical trials and collaborations aimed at enhancing its market position. Financial metrics indicate growth, and the company remains optimistic about future developments. Significant advancements in the pipeline and financial growth are likely to influence investor sentiment and the company's market trajectory.
28 Jan
Athira Pharma, Inc. is evaluating its capacity to invest in growth amidst financial challenges. The company is focused on advancing its clinical programs and enhancing its operational efficiency. However, concerns about its cash reserves and the need for additional funding could impact its growth strategy. Investors are closely monitoring these developments as they could influence the company's future performance and market position. Financial challenges and the need for funding could moderately influence Athira's growth trajectory and market performance.
6 Dec
Athira Pharma presented preclinical data on ATH-1105 at ALS/MND symposium. The presentation of neuroprotective effects could influence competitive positioning.
8 Nov
Athira Pharma explores strategic alternatives after Alzheimer's drug failure, pausing development and laying off employees to save costs. Significant impact likely on future and performance due to major strategic moves, restructuring, and focus on new drug ATH-1105.
7 Nov
Athira Pharma reported financial results for Q3 2024, highlighted progress on ATH-1105 for ALS treatment, and paused development of fosgonimeton for Alzheimer's. The article discusses significant developments in the company's drug pipeline and strategic decisions that could impact its future trajectory.
4 Nov
Athira Pharma, Inc. (ATHA) is one of the top picks for US penny stocks in November 2024. The article highlights significant potential impact on Athira Pharma's future and market performance.
22 Oct
Athira Pharma will present results from Phase 2/3 LIFT-AD clinical trial of fosgonimeton at CTAD 2024 meeting, showing directional improvements in cognition and function in certain subgroups. Results from the LIFT-AD trial could significantly impact Athira Pharma's future development plans and potential treatment options for neurodegenerative diseases.
17 Sep
Athira Pharma plans to focus on advancing ATH-1105 for the treatment of neurodegenerative diseases, including ALS, after completion of Phase 2/3 LIFT-AD clinical trial for Alzheimer's disease drug. Company implements cost containment measures, including a 70% reduction in workforce. Significant impact likely on future and performance due to strategic focus on ATH-1105 development and cost containment measures.
5 Sep
Novavax NVAX obtains FDA approval for updated COVID-19 vaccine, Alnylam ALNY disappoints with study data, Athira Pharma ATHA stock tanks on disappointing trial results, Vaxcyte PCVX stock soars on positive study data, Dyne Therapeutics DYN stock drops on mixed data and executive departures. The disappointing trial results for Athira Pharma ATHA are expected to have a significant impact on its future and market performance.
4 Sep
Athira's drug trial for Alzheimer's failed, causing stock to drop 75%. The failure of the drug trial is a significant event that could alter the company's trajectory and investor sentiment.