LeonaBio, Inc. LONA

3.25 (1.74) (34.87%) as of 25 Sep
Market cap
$54.3M
P/E
0.0×

Insider Decisions

Total sells 0.10
in millions of $
Nov 25 Feb 26 May 26 Aug 26
Buy — — — — — — — — — — — —
Sell — — — 5 — 5 — — — — — —
Insider Ownership 73.15%

Capital & Financial Ratios

Market Cap 54.26
Revenue —
Net Income (141.45)
Free Cash Flow (61.93)
Net Debt (51.07)
Current Ratio 7.01
Debt/Equity 0.00
P/E ratio 0.00
P/S ratio 0.00
P/B ratio 2.30
Past 5Y EPS Growth (73.94%)
This Y EPS Growth 88.52%
Next Y EPS Growth 17.46%
Next 5Y EPS Growth 58.52%
in millions of $

Dividends

Payout Ratio 0.00
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2023 Powerpack
2022 Powerpack
2021 Powerpack
predictions in italic, special payouts not included in total or ratios

Assets vs Liabilities

2023 2024 2025 Q'26
Cash 147 51 88 51
Receivables 2 — — —
Inventory — — — —
Other — — — —
155 55 89 55
2023 2024 2025 Q'26
Payables 0 0 5 2
ST’ Debt — — — —
Other — — 37 —
29 13 48 8
in millions of $

Compound Annual Growth

10y 5y 3y
Sales — — —
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — (36.74%) (50.93%)

Revenue

Year
in millions of $ · fiscal quarters ending in the months shown

Operating Cash Flow

Mar Jun Sep Dec Year
’26 (21) (17) — — —
’25 (15) (7) (5) (19) (46)
’24 (26) (22) (23) (26) (97)
’23 (26) (24) (24) (26) (101)
’22 (17) (19) (22) (16) (72)
’21 (7) (7) (10) (18) (43)
’20 (1) (3) (9) (11) (24)
in millions of $ · fiscal quarters ending in the months shown

Free Cash Flow

Mar Jun Sep Dec Year
’26 (21) (17) — — —
’25 (15) (7) (5) (19) (46)
’24 (26) (22) (23) (26) (97)
’23 (26) (24) (24) (26) (101)
’22 (17) (19) (22) (16) (74)
’21 (8) (7) (10) (19) (45)
’20 (1) (3) (9) (13) (26)
in millions of $ · fiscal quarters ending in the months shown

EPS

Mar Jun Sep Dec Year
’26 (1.73) (0.80) — — —
’25 (2.30) (1.80) (1.68) (18.90) (24.70)
’24 (6.90) (7.00) (7.50) (3.90) (25.20)
’23 (7.30) (7.80) (8.70) (7.10) (30.90)
’22 (5.60) (6.50) (5.30) (7.90) (25.30)
’21 (2.50) (3.80) (4.20) (3.70) (14.90)
’20 (4.82) (4.83) (11.20) (2.40) (16.70)
fiscal quarters ending in the months shown

Target Price Range

Analyst price targets

Recommendation Rating

1
1Buy 2 3Hold 4 5Sell
2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028
— — — — 157.90 88.80 25.30 13.30 4.12 2.20

Analyst estimates 2026–2028

Powerpack
Low Price
— — — — 347.90 342.50 142.20 44.10 42.98 8.36
High Price
— — — — 22 35 64 67 26 19
Employees
— — — — 0 0 0 0 0 0
Revenue/Emp
— — — — — — — — — —
Revenue
— — — — 0.00% 0.00% 0.00% — — —
Gross Margin
— — (5) (5) (20) (55) (96) (118) (97) (106)
EBT
— — 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
EBT Margin
— 0 (5) (5) (20) (55) (96) (118) (97) (106)
Net Income
— — 0 0 0 1 0 0 0 1
Depreciation
— — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Revenue/Sh
— — (14.69) (14.47) (16.70) (14.90) (25.30) (30.90) (25.20) (24.70)
Earnings/Sh
— — (12.92) (10.41) (20.15) (11.67) (19.21) (26.50) (25.25) (10.69)
Cash Flow/Sh
— — 0.00 0.00 (1.94) (0.43) (0.30) (0.08) (0.01) 0.00
Capex/Sh
— — (12.92) (10.41) (22.09) (12.10) (19.51) (26.58) (25.26) (10.69)
Free CF/Sh
— — 6.24 (7.49) 229.20 86.97 62.32 34.24 11.65 6.50
Book Value/Sh
— — 0 0 1 4 4 4 4 4
Shares
— — — — — — — — — —
PE Ratio
— — — — — — — — — —
PS Ratio
— — — — — — — — — —
PB Ratio
— — — — — — — — — —
EV/Sales
— — — — — — — — — —
EV/FCF
— — (4) (4) (24) (43) (72) (101) (97) (46)
Op' Cash Flow
— — — — (2) (2) (1) 0 0 —
Capex
— — (4) (4) (26) (45) (74) (101) (97) (46)
FCF
— — 4 1 188 252 186 126 42 42
Working Cap'
— — 1 2 1 2 2 — — —
Total Debt
— — (4) (1) (184) (252) (199) (147) (51) (88)
Net Debt
— — 2 (3) 274 321 235 130 45 28
Sh' Equity
— — (206.65%) (144.93%) (14.16%) (17.94%) (32.41%) (56.25%) (88.52%) (139.94%)
ROA
— — 0.00% 0.00% (13.81%) (58.03%) (178.71%) 0.00% 0.00% 0.00%
ROIC
— — 29.45% 29.82% (15.68%) (18.43%) (34.39%) (64.42%) (110.77%) (290.81%)
ROE
predictions in italic, sparklines do not include predictions

All 10 years →

LeonaBio, Inc. (LONA) key facts

  • LeonaBio, Inc. (LONA) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • LeonaBio, Inc. reported a net loss of $105.6 million, or a loss of $24.70 per share, for fiscal 2025.
  • As of September 25, 2026, LONA traded at $3.25, a market capitalization of $54.3 million.
  • Return on equity was −290.8% and debt-to-equity 0.00.

Source: company filings (standardised) and stockrow calculations.

LeonaBio, Inc. (LONA) Latest News

News by impact score

Fine-tune

17 Aug

4

LeonaBio beats Q2 loss forecast while advancing Phase 3 ELAINE-3 trial. Beating loss forecasts plus Phase 3 progress signals stronger financials and clinical momentum that can lift valuation and sentiment.

14 Aug

4

Athira Pharma, Inc. presented results from its Phase 1 trial of ATH-1105 at the ALS Nexus 2025 conference. The trial aimed to evaluate the safety and tolerability of ATH-1105 in patients with amyotrophic lateral sclerosis (ALS). Preliminary findings indicated a favorable safety profile and potential efficacy, prompting further investigation into the drug's therapeutic benefits. The presentation garnered attention from the scientific community, highlighting Athira's commitment to advancing treatments for neurodegenerative diseases. The Phase 1 trial results could significantly influence Athira's future product development and market positioning in the ALS treatment landscape.

3

LeonaBio, Inc. (LONA) released second quarter 2026 financial results and a business update. Quarterly earnings release supplies performance data that can shift near-term investor views and valuation.

12 Aug

3

LeonaBio will highlight Lasofoxifene for ER-positive, HER2-negative, ESR1-mutated metastatic breast cancer at DAVA Oncology’s 4th Summit on Breast Cancer. Lasofoxifene presentation at summit may moderately boost visibility for LeonaBio's targeted breast cancer therapy.

4 Jun

3

LeonaBio presented on ATH-1105 at the 5th Annual ALS Drug Development Summit. Presentation at ALS summit may raise visibility for ATH-1105 development program.

7 May

3

LeonaBio, Inc. (LONA) reported first quarter 2026 financial results and provided a business update. Quarterly financial results and business updates moderately influence financial performance and investor sentiment.

3

LeonaBio, Inc. (LONA) appointed Fred Callori, J.D., Natalie Holles, and Peter B. Silverman, J.D. to its Board of Directors. Board appointments of experienced individuals like Fred Callori, Natalie Holles, and Peter B. Silverman enhance governance and strategic positioning with moderate impact on future performance.

23 Apr

3

LeonaBio, Inc. (LONA) will host a virtual Key Opinion Leader event highlighting lasofoxifene's potential in treatment-resistant ER+/HER2-, ESR1-mutated metastatic breast cancer. KOL event on lasofoxifene targets high-unmet need in resistant breast cancer, likely influencing investor sentiment and competitive positioning without guaranteeing transformative outcomes.

21 Apr

3

Independent nonclinical research on Lasofoxifene presented at the American Association for Cancer Research Annual Meeting 2026 aligns with LeonaBio’s data. Independent validation at a major conference moderately bolsters LeonaBio's credibility and market sentiment for its oncology drug candidate.

26 Mar

4

LeonaBio, Inc. (LONA) reported full-year 2025 financial results and provided a business update. Full-year financial results and business updates often drive significant shifts in investor sentiment and stock valuation.

3 Feb

3

LeonaBio, Inc. has appointed Mark F. Kubik as Chief Business Officer. Kubik brings extensive experience in the biotechnology sector, having held leadership roles at various companies. His appointment is expected to enhance LeonaBio's strategic initiatives and business development efforts. The appointment of an experienced executive may positively influence the company's operations and market positioning.

9 Jan

3

Athira Pharma, Inc. has officially changed its name to LeonaBio, Inc., along with a new ticker symbol 'LONA'. This rebranding reflects the company's strategic shift and future direction. The name change and new ticker may influence market perception and branding but are not expected to fundamentally alter the company's trajectory.

18 Dec

4

Athira Pharma, Inc. has secured an exclusive license for the Phase 3 development program of lasofoxifene, a candidate for metastatic breast cancer. The agreement includes a financing arrangement that could total up to $236 million, aimed at advancing the clinical development of this promising therapeutic option. The exclusive licensing and significant financing for a Phase 3 program could substantially enhance Athira's product pipeline and market position.

3

Insiders at Athira Pharma, Inc. have been net buyers of shares in the past year, with Independent Chairwoman Kelly Romano making the largest purchase. Insider transactions may have a moderately noticeable influence on Athira Pharma's future performance.

6 Nov

3

Athira Pharma, Inc. reported its financial results for the third quarter of 2025, highlighting key metrics and developments in its business operations. The company provided updates on its ongoing clinical trials and strategic initiatives aimed at advancing its pipeline. Financial performance showed trends that may influence future growth, while management outlined plans for upcoming product launches and collaborations. The financial results and updates on clinical trials indicate a moderately noticeable influence on the company's future performance and market positioning.

11 Sep

3

Athira Pharma, Inc. announced a reverse stock split aimed at increasing the per-share price of its common stock. The split will be executed at a ratio of 1-for-15, effective on a date to be determined. This move is intended to help the company meet the minimum bid price requirement for continued listing on the Nasdaq. The reverse split will reduce the number of outstanding shares, which may positively influence market perception and investor interest. The reverse stock split is expected to have a moderate influence on market perception and investor interest, but its overall effect on the company's trajectory remains limited.

7 Aug

3

Athira Pharma, Inc. reported its financial results for the second quarter of 2025, highlighting key metrics and updates on its business operations. The company continues to advance its clinical programs and is focused on addressing neurodegenerative diseases. Financial performance showed progress, with increased revenue and reduced losses compared to previous quarters. Management provided insights into future strategies and ongoing research initiatives aimed at enhancing shareholder value. Financial results and updates on clinical programs indicate a moderately noticeable influence on the company's future performance.

14 May

4

Athira Pharma, Inc. announced it will present data from its first-in-human Phase 1 trial of ATH-1105, a novel therapeutic candidate aimed at treating neurodegenerative diseases. The trial's results are expected to provide insights into the safety and efficacy of ATH-1105, potentially advancing the company's pipeline in addressing critical unmet medical needs. The presentation of Phase 1 trial data for ATH-1105 could significantly influence investor sentiment and the company's future trajectory in the neurodegenerative disease market.

13 May

4

Athira Pharma, Inc. announced positive results from a Phase 1 clinical trial of ATH-1105, showing a favorable safety profile and pharmacokinetics in healthy volunteers. The company plans to initiate a clinical trial in ALS patients by late 2025. Data will be presented at the 4th Annual ALS Drug Development Summit, highlighting ATH-1105's potential as a treatment for neurodegenerative diseases, including ALS. The trial involved 80 healthy volunteers and demonstrated robust effects in preclinical models, supporting further development. Positive Phase 1 trial results and plans for ALS patient trials indicate significant potential for future product development and market impact.

9 May

4

Athira Pharma, Inc. reported its Q1 2025 financial results, highlighting the completion of a Phase 1 clinical study of ATH-1105 for ALS, with full data expected in 2H25. The company aims to start dosing ALS patients by late 2025. ATH-1105 has shown promising preclinical results and a favorable safety profile in healthy volunteers. Following disappointing results from its fosgonimeton trial for Alzheimer's, Athira is exploring strategic alternatives and has paused further development of fosgonimeton. As of March 31, 2025, Athira's cash position was $36.7 million, with a net loss of $9.1 million for the quarter. The advancement of ATH-1105 and the exploration of strategic alternatives following the fosgonimeton trial are significant moves that could alter the company's trajectory.

27 Feb

4

Athira Pharma, Inc. reported its full year 2024 financial results, highlighting advancements in its pipeline and business strategies. The company continues to focus on developing therapies for neurodegenerative diseases, with updates on clinical trials and collaborations aimed at enhancing its market position. Financial metrics indicate growth, and the company remains optimistic about future developments. Significant advancements in the pipeline and financial growth are likely to influence investor sentiment and the company's market trajectory.

28 Jan

3

Athira Pharma, Inc. is evaluating its capacity to invest in growth amidst financial challenges. The company is focused on advancing its clinical programs and enhancing its operational efficiency. However, concerns about its cash reserves and the need for additional funding could impact its growth strategy. Investors are closely monitoring these developments as they could influence the company's future performance and market position. Financial challenges and the need for funding could moderately influence Athira's growth trajectory and market performance.

6 Dec

3

Athira Pharma presented preclinical data on ATH-1105 at ALS/MND symposium. The presentation of neuroprotective effects could influence competitive positioning.

8 Nov

4

Athira Pharma explores strategic alternatives after Alzheimer's drug failure, pausing development and laying off employees to save costs. Significant impact likely on future and performance due to major strategic moves, restructuring, and focus on new drug ATH-1105.

7 Nov

4

Athira Pharma reported financial results for Q3 2024, highlighted progress on ATH-1105 for ALS treatment, and paused development of fosgonimeton for Alzheimer's. The article discusses significant developments in the company's drug pipeline and strategic decisions that could impact its future trajectory.

4 Nov

4

Athira Pharma, Inc. (ATHA) is one of the top picks for US penny stocks in November 2024. The article highlights significant potential impact on Athira Pharma's future and market performance.

22 Oct

4

Athira Pharma will present results from Phase 2/3 LIFT-AD clinical trial of fosgonimeton at CTAD 2024 meeting, showing directional improvements in cognition and function in certain subgroups. Results from the LIFT-AD trial could significantly impact Athira Pharma's future development plans and potential treatment options for neurodegenerative diseases.

17 Sep

4

Athira Pharma plans to focus on advancing ATH-1105 for the treatment of neurodegenerative diseases, including ALS, after completion of Phase 2/3 LIFT-AD clinical trial for Alzheimer's disease drug. Company implements cost containment measures, including a 70% reduction in workforce. Significant impact likely on future and performance due to strategic focus on ATH-1105 development and cost containment measures.

5 Sep

4

Novavax NVAX obtains FDA approval for updated COVID-19 vaccine, Alnylam ALNY disappoints with study data, Athira Pharma ATHA stock tanks on disappointing trial results, Vaxcyte PCVX stock soars on positive study data, Dyne Therapeutics DYN stock drops on mixed data and executive departures. The disappointing trial results for Athira Pharma ATHA are expected to have a significant impact on its future and market performance.

4 Sep

4

Athira's drug trial for Alzheimer's failed, causing stock to drop 75%. The failure of the drug trial is a significant event that could alter the company's trajectory and investor sentiment.

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