Cellectis S.A. CLLS
- Market cap
- $103.4M
- P/E
- 0.0×
Follow CLLS
Target Price Range
Analyst price targets
Free account| 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | 2026 | 2027 | 2028 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 16.09 | 17.25 | 15.44 | 9.50 | 7.32 | 7.80 | 1.83 | 0.96 | 1.41 | 1.10 |
Analyst estimates 2026–2028 Powerpack |
Low Price
|
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| 34.99 | 35.07 | 38.85 | 20.84 | 33.59 | 34.71 | 8.82 | 4.04 | 3.38 | 5.48 |
High Price
|
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| 122 | 135 | 171 | 264 | 281 | 294 | 237 | 221 | 222 | 229 |
Employees
|
|||
| 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Revenue/Emp
|
|||
| 56 | 34 | 21 | 23 | 82 | 39 | 26 | 9 | 49 | 80 |
Revenue
|
|||
| 96.85% | 92.23% | 87.22% | 50.45% | 56.01% | 95.22% | 93.11% | 91.98% | 100.00% | 100.00% |
Gross Margin
|
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| (67) | (104) | (88) | (115) | (97) | (97) | (99) | (116) | (37) | (68) |
EBT
|
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| (119.15%) | (307.53%) | (412.15%) | (501.14%) | (118.22%) | (250.66%) | (383.29%) | (1,266.89%) | (74.69%) | (85.46%) |
EBT Margin
|
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| (67) | (104) | (88) | (115) | (97) | (97) | (99) | (117) | (37) | (68) |
Net Income
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| 2 | 3 | 2 | 7 | 10 | 14 | 18 | 19 | 20 | 20 |
Depreciation
|
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| 1.60 | 0.94 | 0.53 | 0.54 | 1.94 | 0.86 | 0.56 | 0.16 | 0.54 | 0.79 |
Revenue/Sh
|
|||
| (1.90) | (2.78) | (1.93) | (2.41) | (1.91) | (2.55) | (2.33) | (1.77) | (0.41) | (0.67) |
Earnings/Sh
|
|||
| (0.93) | (1.47) | (1.67) | (1.63) | (1.89) | (2.33) | (1.92) | (0.43) | 0.25 | (0.39) |
Cash Flow/Sh
|
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| (0.40) | 0.13 | (0.09) | (0.30) | (1.09) | (0.41) | (0.05) | (0.02) | (0.04) | (0.04) |
Capex/Sh
|
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| (1.32) | (1.34) | (1.76) | (1.92) | (2.98) | (2.75) | (1.97) | (0.45) | 0.21 | (0.43) |
Free CF/Sh
|
|||
| 7.79 | 7.96 | 11.04 | 8.38 | 7.27 | 5.28 | 2.77 | 1.49 | 1.45 | 0.76 |
Book Value/Sh
|
|||
| 35 | 36 | 41 | 42 | 43 | 45 | 46 | 57 | 91 | 100 |
Shares
|
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| 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
PE Ratio
|
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| 11.32 | 31.85 | 31.68 | 31.61 | 13.95 | 9.43 | 4.02 | 19.04 | 3.31 | 6.10 |
PS Ratio
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| 2.33 | 3.78 | 1.51 | 2.04 | 3.72 | 1.54 | 0.82 | 2.07 | 1.24 | 6.39 |
PB Ratio
|
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| 6.20 | 23.05 | 10.65 | 17.98 | 11.13 | 5.19 | 1.22 | 2.79 | (0.62) | 4.54 |
EV/Sales
|
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| (7.49) | (16.25) | (3.18) | (5.06) | (7.25) | (1.63) | (0.35) | (0.93) | (1.58) | (8.18) |
EV/FCF
|
|||
| (33) | (52) | (68) | (69) | (80) | (105) | (87) | (25) | 23 | (39) |
Op' Cash Flow
|
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| (14) | 5 | (4) | (13) | (46) | (19) | (2) | (1) | (4) | (4) |
Capex
|
|||
| (47) | (48) | (72) | (82) | (126) | (123) | (90) | (26) | 19 | (43) |
FCF
|
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| 256 | 278 | 441 | 329 | 263 | 176 | 81 | 78 | 121 | 90 |
Working Cap'
|
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| 2 | 0 | 1 | 48 | 36 | 22 | 26 | 54 | 67 | 84 |
Total Debt
|
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| (289) | (297) | (451) | (313) | (233) | (164) | (72) | (149) | (193) | (124) |
Net Debt
|
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| 275 | 284 | 450 | 355 | 309 | 236 | 126 | 85 | 131 | 76 |
Sh' Equity
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| (18.94%) | (29.92%) | (18.88%) | (21.09%) | (17.31%) | (26.82%) | (33.00%) | (33.94%) | (10.24%) | (19.09%) |
ROA
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| 0.00% | 0.00% | 0.00% | (182.91%) | (70.08%) | (88.93%) | (104.04%) | 0.00% | 0.00% | 0.00% |
ROIC
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| (23.71%) | (35.57%) | (21.43%) | (25.34%) | (24.41%) | (41.88%) | (58.57%) | (95.96%) | (34.08%) | (65.33%) |
ROE
|
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Cellectis S.A. peers in Biotechnology
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| SEER Seer, Inc. | $103.6M | 0.0× | Compare |
| PMN Promis Neurosciences | $103.8M | 0.0× | Compare |
| PMVP PMV Pharmaceuticals, Inc. | $100.8M | 0.0× | Compare |
| RANI Rani Therapeutics Holdings, Inc. | $107.3M | 0.0× | Compare |
| Company | Market cap | P/E | Compare |
|---|---|---|---|
| CRDF Cardiff Oncology, Inc. | $99.6M | 0.0× | Compare |
| BMEA Biomea Fusion, Inc. | $108.0M | 0.0× | Compare |
| MIST Milestone Pharmaceuticals Inc. | $99.0M | 0.0× | Compare |
| BDTX Black Diamond Therapeutics, Inc. | $108.6M | 0.0× | Compare |
Cellectis S.A. (CLLS) key facts
- Cellectis S.A. (CLLS) is a Biotechnology company in the Healthcare sector, traded in the US as an ADR.
- Cellectis S.A.’s revenue for fiscal 2025 (year ended December 2025) was EUR 79.6 million, up 61.7% from fiscal 2024.
- As of September 25, 2026, CLLS traded at $1.47, a market capitalization of $103.4 million.
- Return on equity was −65.3% and debt-to-equity 1.79.
Cellectis S.A. (CLLS) Latest News
17 Sep
Cellectis exits two CAR-T programs, prompting questions on whether gene editing can justify the clinical reset. Exiting two CAR-T programs marks a major strategic move that could significantly alter the company's development trajectory and investor sentiment.
15 Sep
CLLS stock heads toward 14-month low after 40% drop. Citizens flags delayed catalysts following Cellectis cancer pipeline pivot. Pipeline pivot triggers catalyst delays and 40% stock decline toward 14-month lows.
14 Sep
Cellectis S.A. transforms focus to in vivo gene editing and exits Lasme-cel and Eti-cel development. Exiting two programs to pursue in vivo gene editing marks major strategic shift with significant effects on trajectory.
Cellectis S.A. exits CAR-T programs and shifts focus to in vivo gene editing. Exit from CAR-T and pivot to in vivo gene editing marks major strategic shift for Cellectis.
Cellectis S.A. announces strategic transformation into an in vivo gene editing company. Strategic shift to in vivo gene editing marks major move likely to significantly alter company trajectory and investor sentiment.
11 Jun
Cellectis S.A. reports Phase 1 Lasme-cel study results showing 100% response rate in B-Cell Leukemia patients. Strong early-stage efficacy data for lead candidate can boost valuation and trial progress.
Cellectis presented final Phase 1 results of Lasme-cel and preliminary results on Eti-cel at EHA 2026 Congress. Phase 1 data release may moderately shift investor views on pipeline without guaranteeing approvals or revenue.
9 Jun
CLLS stock rose over 24% in after-hours trading following an unspecified positive development. Sharp after-hours gain signals major investor reaction that can materially shift near-term valuation and sentiment.
Cellectis S.A. obtained FDA RMAT designation for lasme-cel, the first allogeneic CAR-T therapy in a pivotal trial for relapsed/refractory B-ALL patients. RMAT designation accelerates lasme-cel development and approval timeline as first allogeneic CAR-T in pivotal r/r B-ALL trial.
12 May
Cellectis announces presentation of clinical data on Lasme-cel and Eti-cel at the EHA 2026 Annual Congress. Clinical data presentation at a major hematology congress signals key pipeline advancements for Lasme-cel and Eti-cel, likely boosting investor sentiment and competitive positioning.
11 May
Cellectis S.A. (CLLS) reported financial results for the first quarter of 2026, detailing revenue, expenses, cash position, and operational updates. Quarterly financial results for a biotech firm like Cellectis directly impact investor sentiment, stock price, and perceived financial health.
27 Apr
Cellectis presented its epigenetic editing platform at the ASGCT Annual Meeting, enabling gene silencing without altering DNA sequence. Novel epigenetic editing platform advances Cellectis' gene therapy pipeline with potentially safer, non-DNA-cutting technology.
13 Apr
Cellectis S.A. (CLLS) announces positive interim data from the Cema-Cel pivotal trial, emphasizing the strength of its allogeneic CAR-T platform. Positive interim data from Cema-Cel pivotal trial validates Cellectis' allogeneic CAR-T platform, likely driving significant improvements in competitive positioning and investor sentiment.
20 Mar
Cellectis SA (CLLS) reported promising clinical progress and strategic advancements in its Q4 2025 earnings call, highlighting key developments in gene-editing therapies and partnerships. Promising clinical progress and strategic initiatives directly bolster CLLS's biotech pipeline and investor outlook.
19 Mar
Cellectis S.A. (CLLS) reported full year 2025 financial results and provided a business update. Full year financial results and business update represent major disclosures likely to alter investor sentiment and company trajectory.
23 Jan
Cellectis S.A. (CLLS) is highlighted among European penny stocks with market caps exceeding €100 million. The company is noted for its advancements in gene-editing technologies and potential applications in cancer therapies. Investors are encouraged to monitor Cellectis as it navigates the evolving biotech landscape, which may present opportunities for growth and innovation. Cellectis is positioned in a competitive biotech sector where advancements can moderately influence its market performance.
8 Jan
Cellectis S.A. has unveiled its strategic plan for 2026, outlining key catalysts aimed at advancing its gene-editing technologies and enhancing its product pipeline. The company aims to strengthen its position in the cell therapy market and accelerate the development of its innovative therapies. Key milestones include upcoming clinical trials and partnerships that are expected to drive growth and investor interest. The strategic initiatives and upcoming clinical trials are likely to significantly impact Cellectis's market position and investor sentiment.
15 Dec
Cellectis S.A. announced an arbitral decision regarding its dispute with Servier, which has implications for their collaboration on gene-editing therapies. The ruling is expected to influence the ongoing partnership and future developments in their joint projects. Cellectis aims to leverage this decision to enhance its strategic position in the market. The arbitral decision is likely to significantly impact the strategic partnership and future product development between Cellectis and Servier.
Allogene Therapeutics has reported a favorable arbitration result for Servier against Cellectis S.A. The decision is expected to impact Cellectis's operations and market position, as it relates to ongoing legal disputes and potential financial implications. The arbitration outcome may moderately influence Cellectis's competitive positioning and financial performance.
11 Dec
Cellectis S.A. (CLLS) is highlighted as one of three European penny stocks with market capitalizations under €400 million. The article discusses the company's position within the biotech sector and its potential for growth, emphasizing the importance of market dynamics and investor sentiment in shaping its future performance. Cellectis S.A. operates in a competitive biotech landscape, and while it has growth potential, its current market cap limits immediate transformative impacts.
8 Dec
Cellectis S.A. presented its development plan at ASH 2025 to enhance the high response rate observed for its product, Eti-cel, in patients with relapsed/refractory non-Hodgkin lymphoma (r/r NHL). The company aims to build on the promising results and further improve treatment outcomes for this patient population. The development plan for Eti-cel could significantly impact Cellectis's market position and investor sentiment in the oncology sector.
25 Nov
Cellectis S.A. (CLLS) saw its American Depositary Receipts (ADRs) rise sharply in Tuesday trading, reflecting a broader trend in European equities traded in the US. This surge indicates increased investor interest and positive market sentiment towards European stocks, including Cellectis. The rise in ADRs suggests a moderately noticeable influence on market sentiment and potential financial performance for Cellectis.
21 Nov
Cellectis S.A. and Moligo Technologies have showcased the potential of enzymatic single-stranded DNA for non-viral gene editing in a study published in Nature Communications. This innovative approach could enhance gene editing techniques, offering a promising alternative to traditional methods, and may pave the way for advancements in therapeutic applications. The demonstration of a new gene editing technology could significantly impact Cellectis's strategic positioning and market opportunities.
19 Nov
Cellectis S.A. has published a study in Nature Communications detailing a novel non-viral gene editing process that enhances gene insertion efficiency in hematopoietic stem cells. This innovative technique aims to improve therapeutic applications in gene therapy and regenerative medicine, potentially advancing treatment options for various blood disorders. The development of a non-viral gene editing process could significantly enhance Cellectis's competitive position and product offerings in the gene therapy market.
7 Nov
Cellectis S.A. reported its financial results for the third quarter of 2025, highlighting key metrics and developments in its business operations. The company provided updates on its ongoing projects and strategic initiatives, reflecting its focus on advancing its gene-editing technologies and expanding its market presence. Financial performance indicators showed trends that may influence future growth and investor sentiment. The financial results and business updates indicate moderate influences on Cellectis's performance and market positioning.
3 Nov
Cellectis S.A. announced plans to present a development update for its product eti-cel at the upcoming ASH 2025 conference. This presentation is expected to provide insights into the progress and future direction of eti-cel, a key asset in Cellectis' portfolio. The presentation at ASH 2025 could significantly influence investor sentiment and the company's strategic positioning in the market.
16 Oct
Cellectis S.A. highlighted the potential of its product, lasme-cel, during its R&D Day, emphasizing its ability to address significant unmet needs for patients with relapsed/refractory B-cell acute lymphoblastic leukemia (r/r B-ALL). The presentation showcased promising data and the company's commitment to advancing its innovative therapies in the oncology space. Lasme-cel's potential to meet a significant unmet medical need could lead to major strategic advantages and influence investor sentiment.
Cellectis S.A. hosted an R&D Day to highlight advancements in its pipeline and discuss long-term value drivers. The event showcased the company's progress in developing innovative therapies, emphasizing its commitment to enhancing patient outcomes and addressing unmet medical needs. Key presentations included updates on ongoing clinical trials and strategic initiatives aimed at strengthening Cellectis' position in the biotech industry. Significant advancements in the pipeline and strategic initiatives could notably influence Cellectis' future performance and market perception.
14 Oct
Allogene Therapeutics is facing patent infringement challenges that could impact its operations and market position. The company is involved in legal disputes regarding its intellectual property, which may affect its product development and competitive landscape. These challenges come at a critical time as Allogene seeks to advance its therapies in the biopharmaceutical sector. Patent infringement challenges could moderately influence Allogene's competitive positioning and product development efforts.
8 Oct
Cellectis S.A. (CLLS) is highlighted as a notable penny stock to watch in October 2025 due to its advancements in gene editing technologies and potential partnerships that could enhance its market position. The company is focusing on innovative therapies that may attract investor interest, especially in the context of the growing biotech sector in Europe. Analysts suggest that Cellectis's strategic initiatives could lead to increased visibility and valuation in the coming months. Significant advancements in gene editing and potential partnerships could greatly influence Cellectis's market position and investor sentiment.