Cellectis S.A.

CLLS Healthcare Biotechnology

Cellectis S.A.’s revenue for fiscal 2025 (year ended December 2025) was $79.6 million, up 61.7% from fiscal 2024. In the quarter to June 2026, revenue fell 62.1%, EPS grew 8.33%, free cash flow fell 37.0% and total debt was flat, each against the same quarter a year earlier.

1.04 0.07 −6.31%
Market cap
$79.9M
P/E
0.0×
Fwd P/E
—
Dividend yield
—
F-score
2/9
Altman Z
−0.03
Beneish M
−2.61
Dividend safety
n/a

Insider Decisions trades per month

Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — — — — — —
Sell — — — — — — — — — — — —
Insider Ownership 30.97%

Capital & Financial Ratios $m

Market Cap 79.92
Revenue 63.82
Net Income (65.31)
Free Cash Flow (43.80)
Net Debt (93.16)
Current Ratio 1.37
Debt/Equity 1.79
P/E ratio 0.00
Fwd P/E —
P/S ratio 1.64
P/B ratio 2.55
Past 5Y EPS Growth —
This Y EPS Growth (19.90%) (below 0%: weak)
Next Y EPS Growth 17.01% (at or above 15%: strong)
Next Y revenue growth —
Next 5Y EPS Growth (26.03%) (below 0%: weak)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 0.04%
10-year low 10-year high
P/B against its own 10 years 63.62%
10-year low 10-year high
EV/Sales against its own 10 years 1.01%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 204 260 209 167
Receivables 21 21 22 13
Inventory — — — —
Other 8 6 5 5
233 287 236 184
2023 2024 2025 Q'26
Payables 19 19 17 18
ST’ Debt 5 16 10 8
Other 12 11 14 12
155 166 146 135

Compound Annual Growth %

10y 5y 3y
Sales 3.60% (0.70%) 45.72%
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value (12.63%) (24.47%) (15.53%)

Revenue $m

Mar Jun Sep Dec Year
’26 8 7 — — —
’25 12 18 37 12 80
’24 6 10 18 15 49
’23 4 2 2 2 9
’22 4 3 2 17 26
’21 28 15 11 (15) 39
’20 52 5 9 17 82
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (15) (14) — — —
’25 (17) (10) (2) (10) (39)
’24 (23) 52 (6) 0 23
’23 (28) (19) (17) 40 (25)
’22 (37) (24) (26) (1) (87)
’21 (41) (12) (30) (21) (105)
’20 1 (22) (26) (34) (80)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (16) (15) — — —
’25 (18) (11) (4) (11) (43)
’24 (24) 51 (7) (2) 19
’23 (29) (21) (17) 39 (26)
’22 (37) (25) (27) (1) (90)
’21 (49) (18) (36) (21) (123)
’20 (6) (36) (32) (52) (126)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.18) (0.22) — — —
’25 (0.18) (0.24) 0.01 (0.26) (0.67)
’24 0.05 (0.28) (0.23) 0.05 (0.41)
’23 (0.58) (0.19) (0.31) (0.64) (1.77)
’22 (0.70) (0.42) (0.63) (0.59) (2.33)
’21 (0.28) (0.88) (0.82) (0.55) (2.55)
’20 0.47 (0.76) (0.71) (0.95) (1.91)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

2.3
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low 16.09 17.25 15.44 9.50 7.32 7.80 1.83 0.96 1.41 1.10

Analyst estimates 2026–2028

Powerpack
High 34.99 35.07 38.85 20.84 33.59 34.71 8.82 4.04 3.38 5.48
People
People Employees 122 135 171 264 281 294 237 221 222 229
Revenue/emp, $m 0.46 0.25 0.13 0.09 0.29 0.13 0.11 0.04 0.22 0.35
Income, $m
Income, $m Revenue 56 34 21 23 82 39 26 9 49 80
Gross margin, % 96.85 92.23 87.22 50.45 56.01 95.22 93.11 91.98 100.00 100.00
EBT (67) (104) (88) (115) (97) (97) (99) (116) (37) (68)
EBT margin, % (119.15) (307.53) (412.15) (501.14) (118.22) (250.66) (383.29) (1,266.89) (74.69) (85.46)
Net income (67) (104) (88) (115) (97) (97) (99) (117) (37) (68)
Depreciation 2 3 2 7 10 14 18 19 20 20
Per share, $
Per share, $ Revenue 1.60 0.94 0.53 0.54 1.94 0.86 0.56 0.16 0.54 0.79
Earnings (1.90) (2.78) (1.93) (2.41) (1.91) (2.55) (2.33) (1.77) (0.41) (0.67)
Cash flow (0.93) (1.47) (1.67) (1.63) (1.89) (2.33) (1.92) (0.43) 0.25 (0.39)
Capex (0.40) 0.13 (0.09) (0.30) (1.09) (0.41) (0.05) (0.02) (0.04) (0.04)
Free cash flow (1.32) (1.34) (1.76) (1.92) (2.98) (2.75) (1.97) (0.45) 0.21 (0.43)
Book value 7.79 7.96 11.04 8.38 7.27 5.28 2.77 1.49 1.45 0.76
Shares, m 35 36 41 42 43 45 46 57 91 100
Valuation, ×
Valuation, × P/E 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
P/S 11.32 31.85 31.68 31.61 13.95 9.43 4.02 19.04 3.31 6.10
P/B 2.33 3.78 1.51 2.04 3.72 1.54 0.82 2.07 1.24 6.39
EV/Sales 6.20 23.05 10.65 17.98 11.13 5.19 1.22 2.79 (0.62) 4.54
EV/FCF (7.49) (16.25) (3.18) (5.06) (7.25) (1.63) (0.35) (0.93) (1.58) (8.18)
Cash, $m
Cash, $m Operating cash flow (33) (52) (68) (69) (80) (105) (87) (25) 23 (39)
Capex (14) 5 (4) (13) (46) (19) (2) (1) (4) (4)
Free cash flow (47) (48) (72) (82) (126) (123) (90) (26) 19 (43)
Balance, $m
Balance, $m Working capital 256 278 441 329 263 176 81 78 121 90
Total debt 2 0 1 48 36 22 26 54 67 84
Net debt (289) (297) (451) (313) (233) (164) (72) (149) (193) (124)
Shareholders’ equity 275 284 450 355 309 236 126 85 131 76
Returns, %
Returns, % ROA (18.94) (29.92) (18.88) (21.09) (17.31) (26.82) (33.00) (33.94) (10.24) (19.09)
ROIC 0.00 0.00 0.00 (182.91) (70.08) (88.93) (104.04) 0.00 0.00 0.00
ROE (23.71) (35.57) (21.43) (25.34) (24.41) (41.88) (58.57) (95.96) (34.08) (65.33)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Charts ten years each

Cellectis S.A. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
AARD Aardvark Therapeutics, Inc. $84.5M — (loss-making) — — n/m −77.14% (below 0%: shrinking) — 0.00% Compare
CRBP Corbus Pharmaceuticals Holdings, Inc. $83.8M — (loss-making) — (loss-making) −92.09% (below 0%: shrinking) n/m −78.52% (below 0%: shrinking) 0.00% 0.00% Compare
EQ Equillium, Inc. $83.7M — (loss-making) — (loss-making) −52.32% (below 0%: shrinking) n/m −38.67% (below 0%: shrinking) 100.00% 0.00% Compare
NMRA Neumora Therapeutics, Inc. $80.2M — (loss-making) — — n/m +24.45% (above 0%: growing) 0.00% 0.00% Compare
CLLS Cellectis S.A. $79.9M — (loss-making) — −62.05% (below 0%: shrinking) n/m −36.95% (below 0%: shrinking) 100.00% (340.69%)
PMN Promis Neurosciences $78.0M — (loss-making) — 0.00% n/m −169.46% (below 0%: shrinking) 0.00% 0.00% Compare
PTHS Pelthos Therapeutics Inc. $77.6M — (loss-making) — (loss-making) — n/m −1,614.99% (below 0%: shrinking) 76.86% (111.02%) Compare
TELO Telomir Pharmaceuticals, Inc. $77.3M — (loss-making) — — n/m −45.34% (below 0%: shrinking) — 0.00% Compare
NTRB Nutriband Inc. $76.2M — (loss-making) 4.6× −29.72% (below 0%: shrinking) n/m +55.46% (above 0%: growing) 41.58% (203.57%) Compare
Median of peers $79.1M — — −41.02% — −61.24% 20.79% 0.00%

All 614 Biotechnology stocks →

Cellectis S.A. (CLLS) key facts

  • Strength: Cellectis S.A.’s revenue for fiscal 2025 (year ended December 2025) was $79.6 million, up 61.7% from fiscal 2024.
  • Cellectis S.A. (CLLS) is a Biotechnology company in the Healthcare sector, traded in the US as an ADR.
  • As of October 16, 2026, CLLS traded at $1.04, a market capitalization of $79.9 million.
  • Return on equity was −65.3% and debt-to-equity 1.79.
  • Its Piotroski F-score is 2 out of 9 and its Altman Z-score is −0.03 (distress zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

Cellectis S.A. (CLLS) Latest News

stockrow.com/CLLS · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com