Saturday 17 October 2026
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Cellectis S.A.
CLLS Healthcare Biotechnology
Cellectis S.A.’s revenue for fiscal 2025 (year ended December 2025) was $79.6 million, up 61.7% from fiscal 2024. In the quarter to June 2026, revenue fell 62.1%, EPS grew 8.33%, free cash flow fell 37.0% and total debt was flat, each against the same quarter a year earlier.
1.04
0.07
−6.31%
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Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Trend | 2026e | 2027e | 2028e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Price, $ | |||||||||||||||
| Price, $ | Low | 16.09 | 17.25 | 15.44 | 9.50 | 7.32 | 7.80 | 1.83 | 0.96 | 1.41 | 1.10 |
Analyst estimates 2026–2028 Powerpack |
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| High | 34.99 | 35.07 | 38.85 | 20.84 | 33.59 | 34.71 | 8.82 | 4.04 | 3.38 | 5.48 | |||||
| People | |||||||||||||||
| People | Employees | 122 | 135 | 171 | 264 | 281 | 294 | 237 | 221 | 222 | 229 | ||||
| Revenue/emp, $m | 0.46 | 0.25 | 0.13 | 0.09 | 0.29 | 0.13 | 0.11 | 0.04 | 0.22 | 0.35 | |||||
| Income, $m | |||||||||||||||
| Income, $m | Revenue | 56 | 34 | 21 | 23 | 82 | 39 | 26 | 9 | 49 | 80 | ||||
| Gross margin, % | 96.85 | 92.23 | 87.22 | 50.45 | 56.01 | 95.22 | 93.11 | 91.98 | 100.00 | 100.00 | |||||
| EBT | (67) | (104) | (88) | (115) | (97) | (97) | (99) | (116) | (37) | (68) | |||||
| EBT margin, % | (119.15) | (307.53) | (412.15) | (501.14) | (118.22) | (250.66) | (383.29) | (1,266.89) | (74.69) | (85.46) | |||||
| Net income | (67) | (104) | (88) | (115) | (97) | (97) | (99) | (117) | (37) | (68) | |||||
| Depreciation | 2 | 3 | 2 | 7 | 10 | 14 | 18 | 19 | 20 | 20 | |||||
| Per share, $ | |||||||||||||||
| Per share, $ | Revenue | 1.60 | 0.94 | 0.53 | 0.54 | 1.94 | 0.86 | 0.56 | 0.16 | 0.54 | 0.79 | ||||
| Earnings | (1.90) | (2.78) | (1.93) | (2.41) | (1.91) | (2.55) | (2.33) | (1.77) | (0.41) | (0.67) | |||||
| Cash flow | (0.93) | (1.47) | (1.67) | (1.63) | (1.89) | (2.33) | (1.92) | (0.43) | 0.25 | (0.39) | |||||
| Capex | (0.40) | 0.13 | (0.09) | (0.30) | (1.09) | (0.41) | (0.05) | (0.02) | (0.04) | (0.04) | |||||
| Free cash flow | (1.32) | (1.34) | (1.76) | (1.92) | (2.98) | (2.75) | (1.97) | (0.45) | 0.21 | (0.43) | |||||
| Book value | 7.79 | 7.96 | 11.04 | 8.38 | 7.27 | 5.28 | 2.77 | 1.49 | 1.45 | 0.76 | |||||
| Shares, m | 35 | 36 | 41 | 42 | 43 | 45 | 46 | 57 | 91 | 100 | |||||
| Valuation, × | |||||||||||||||
| Valuation, × | P/E | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||
| P/S | 11.32 | 31.85 | 31.68 | 31.61 | 13.95 | 9.43 | 4.02 | 19.04 | 3.31 | 6.10 | |||||
| P/B | 2.33 | 3.78 | 1.51 | 2.04 | 3.72 | 1.54 | 0.82 | 2.07 | 1.24 | 6.39 | |||||
| EV/Sales | 6.20 | 23.05 | 10.65 | 17.98 | 11.13 | 5.19 | 1.22 | 2.79 | (0.62) | 4.54 | |||||
| EV/FCF | (7.49) | (16.25) | (3.18) | (5.06) | (7.25) | (1.63) | (0.35) | (0.93) | (1.58) | (8.18) | |||||
| Cash, $m | |||||||||||||||
| Cash, $m | Operating cash flow | (33) | (52) | (68) | (69) | (80) | (105) | (87) | (25) | 23 | (39) | ||||
| Capex | (14) | 5 | (4) | (13) | (46) | (19) | (2) | (1) | (4) | (4) | |||||
| Free cash flow | (47) | (48) | (72) | (82) | (126) | (123) | (90) | (26) | 19 | (43) | |||||
| Balance, $m | |||||||||||||||
| Balance, $m | Working capital | 256 | 278 | 441 | 329 | 263 | 176 | 81 | 78 | 121 | 90 | ||||
| Total debt | 2 | 0 | 1 | 48 | 36 | 22 | 26 | 54 | 67 | 84 | |||||
| Net debt | (289) | (297) | (451) | (313) | (233) | (164) | (72) | (149) | (193) | (124) | |||||
| Shareholders’ equity | 275 | 284 | 450 | 355 | 309 | 236 | 126 | 85 | 131 | 76 | |||||
| Returns, % | |||||||||||||||
| Returns, % | ROA | (18.94) | (29.92) | (18.88) | (21.09) | (17.31) | (26.82) | (33.00) | (33.94) | (10.24) | (19.09) | ||||
| ROIC | 0.00 | 0.00 | 0.00 | (182.91) | (70.08) | (88.93) | (104.04) | 0.00 | 0.00 | 0.00 | |||||
| ROE | (23.71) | (35.57) | (21.43) | (25.34) | (24.41) | (41.88) | (58.57) | (95.96) | (34.08) | (65.33) | |||||
Negative figures in brackets.
Fiscal years to Dec 2025 · latest quarter Jun 2026
Charts ten years each
Cellectis S.A. vs peers in Biotechnology (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| AARD Aardvark Therapeutics, Inc. | $84.5M | — (loss-making) | — | — | n/m | −77.14% (below 0%: shrinking) | — | 0.00% | Compare |
| CRBP Corbus Pharmaceuticals Holdings, Inc. | $83.8M | — (loss-making) | — (loss-making) | −92.09% (below 0%: shrinking) | n/m | −78.52% (below 0%: shrinking) | 0.00% | 0.00% | Compare |
| EQ Equillium, Inc. | $83.7M | — (loss-making) | — (loss-making) | −52.32% (below 0%: shrinking) | n/m | −38.67% (below 0%: shrinking) | 100.00% | 0.00% | Compare |
| NMRA Neumora Therapeutics, Inc. | $80.2M | — (loss-making) | — | — | n/m | +24.45% (above 0%: growing) | 0.00% | 0.00% | Compare |
| CLLS Cellectis S.A. | $79.9M | — (loss-making) | — | −62.05% (below 0%: shrinking) | n/m | −36.95% (below 0%: shrinking) | 100.00% | (340.69%) | |
| PMN Promis Neurosciences | $78.0M | — (loss-making) | — | 0.00% | n/m | −169.46% (below 0%: shrinking) | 0.00% | 0.00% | Compare |
| PTHS Pelthos Therapeutics Inc. | $77.6M | — (loss-making) | — (loss-making) | — | n/m | −1,614.99% (below 0%: shrinking) | 76.86% | (111.02%) | Compare |
| TELO Telomir Pharmaceuticals, Inc. | $77.3M | — (loss-making) | — | — | n/m | −45.34% (below 0%: shrinking) | — | 0.00% | Compare |
| NTRB Nutriband Inc. | $76.2M | — (loss-making) | 4.6× | −29.72% (below 0%: shrinking) | n/m | +55.46% (above 0%: growing) | 41.58% | (203.57%) | Compare |
| Median of peers | $79.1M | — | — | −41.02% | — | −61.24% | 20.79% | 0.00% |
Cellectis S.A. (CLLS) key facts
- Strength: Cellectis S.A.’s revenue for fiscal 2025 (year ended December 2025) was $79.6 million, up 61.7% from fiscal 2024.
- Cellectis S.A. (CLLS) is a Biotechnology company in the Healthcare sector, traded in the US as an ADR.
- As of October 16, 2026, CLLS traded at $1.04, a market capitalization of $79.9 million.
- Return on equity was −65.3% and debt-to-equity 1.79.
- Its Piotroski F-score is 2 out of 9 and its Altman Z-score is −0.03 (distress zone) for fiscal 2025.