Caris Life Sciences,�Inc.

CAI Healthcare Biotechnology

Caris Life Sciences,�Inc.’s revenue for fiscal 2025 (year ended December 2025) was $812.0 million, up 97.0% from fiscal 2024.

Revenue
+27.0%
EPS
−40.3%
Free cash flow
−140.2%
Total debt
+4.46%

Quarter to September 2026, against a year earlier

24.78 1.25 −4.80%
Market cap
$7.4B
P/E
77.7×
Fwd P/E
254×
Dividend yield
—
F-score
n/a
Altman Z
3.55
Beneish M
−2.71
Dividend safety
n/a

Caris Life Sciences,�Inc. (CAI) Operating margin

Alert me on Operating margin

Caris Life Sciences,�Inc.'s operating margin over the twelve months to 30 September 2026 was 13.4%, up 7.8 percentage points from fiscal 2025 (5.56%). That is above the Biotechnology industry median of 0.00% and above the Healthcare sector median of 0.00%.

Operating margin, annual

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Annual newest first

Period Operating margin Change (points)
FY2025 5.56% 67.93
FY2024 −62.4% 42.01
FY2023 −104.4% —

Quarterly newest first

Period Operating margin Change (points)
Sep 2026 7.01% (3.20)
Jun 2026 10.2% 7.77
Mar 2026 2.44% (27.75)
Dec 2025 30.2% 15.14
5 more quarters

Operating margin against peers

Company Operating margin
KRYS Krystal Biotech, Inc. compare 48.4%
PTGX Protagonist Therapeutics, Inc. compare 20.7%
TGTX TG Therapeutics, Inc. compare 17.1%
CAI Caris Life Sciences,�Inc. 13.4%
SYRE Spyre Therapeutics, Inc. compare 0.00%
MDGL Madrigal Pharmaceuticals, Inc. compare −10.7%
TWST Twist Bioscience Corporation compare −33.6%
IBRX ImmunityBio, Inc. compare −151.9%
CYTK Cytokinetics, Incorporated compare −625.2%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Operating margin is

EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.

EBIT ÷ Revenue

The full definition of Operating margin →

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