Annexon, Inc.

ANNX Healthcare Biotechnology

In the quarter to June 2026, EPS grew 17.7% and free cash flow fell 26.4%, each against the same quarter a year earlier. Insiders bought in the last twelve months.

3.41 0.19 −5.28%
Market cap
$682.5M
P/E
0.0×
Fwd P/E
—
Dividend yield
—
F-score
n/a
Altman Z
n/a
Beneish M
n/a
Dividend safety
n/a

Insider Decisions trades per month

Total buys 12.39
Total sells 0.31
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy 2 3 — — 1 1 2 — — — 1 —
Sell — — — 5 5 — — — — — — —
Insider Ownership 17.95%

Capital & Financial Ratios $m

Market Cap 682.49
Revenue —
Net Income (202.67)
Free Cash Flow (193.23)
Net Debt (209.24)
Current Ratio 5.53 (at or above 1.5: strong)
Debt/Equity 0.00 (at or below 0.5: strong)
P/E ratio 0.00
Fwd P/E —
P/S ratio 0.00
P/B ratio 3.68
Past 5Y EPS Growth —
This Y EPS Growth 21.78% (at or above 15%: strong)
Next Y EPS Growth 5.20%
Next Y revenue growth —
Next 5Y EPS Growth 44.25% (at or above 15%: strong)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/B against its own 10 years 85.65%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2018 Powerpack
special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 260 312 238 209
Receivables — — — —
Inventory — — — —
Other — — — —
264 316 242 213
2023 2024 2025 Q'26
Payables 5 10 15 16
ST’ Debt — — — —
Other — — — —
18 31 43 38

Compound Annual Growth %

10y 5y 3y
Sales — — —
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — (9.27%) (2.90%)

Revenue $m

Year
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (47) (48) — — —
’25 (50) (38) (52) (46) (186)
’24 (28) (22) (32) (36) (118)
’23 (33) (36) (28) (23) (121)
’22 (30) (28) (31) (27) (116)
’21 (23) (25) (30) (28) (106)
’20 (10) (10) (14) (19) (53)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (47) (48) — — —
’25 (50) (38) (52) (46) (186)
’24 (28) (22) (32) (36) (118)
’23 (33) (36) (28) (23) (121)
’22 (36) (29) (31) (27) (123)
’21 (23) (25) (30) (29) (108)
’20 (10) (10) (14) (19) (54)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.23) (0.28) — — —
’25 (0.37) (0.34) (0.37) (0.28) (1.34)
’24 (0.21) (0.23) (0.25) (0.33) (1.01)
’23 (0.52) (0.47) (0.43) (0.36) (1.77)
’22 (0.92) (0.96) (0.51) (0.48) (2.60)
’21 (0.68) (0.82) (0.93) (0.97) (3.40)
’20 (28.45) (28.87) (0.77) (0.61) (4.15)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.4
1Buy 2 3Hold 4 5Sell

Ten years at a glance

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low — — — — 15.33 11.34 2.06 1.57 3.86 1.29

Analyst estimates 2026–2028

Powerpack
High — — — — 31.94 38.01 11.95 7.65 8.40 5.66
People
People Employees — — — 30 48 61 80 71 100 96
Revenue/emp, $m — — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Income, $m
Income, $m Revenue — — — — — — — — — —
Gross margin, % — 0.00 0.00 0.00 0.00 0.00 0.00 — — —
EBT — (19) (18) (37) (63) (130) (142) (134) (138) (207)
EBT margin, % — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Net income — 0 (18) (37) (63) (130) (142) (134) (138) (207)
Depreciation — 0 0 0 1 2 2 2 2 2
Per share, $
Per share, $ Revenue — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Earnings — (0.49) (45.45) (85.78) (4.15) (3.40) (2.60) (1.77) (1.01) (1.34)
Cash flow — (0.50) (42.69) (65.42) (3.13) (2.77) (2.13) (1.60) (0.86) (1.20)
Capex — 0.00 (0.04) (0.62) (0.03) (0.04) (0.12) 0.00 0.00 0.00
Free cash flow — (0.50) (42.73) (66.03) (3.16) (2.81) (2.25) (1.60) (0.86) (1.20)
Book value — (1.21) (159.43) (231.73) 20.30 6.05 4.23 3.31 2.13 1.36
Shares, m — 38 0 0 17 38 55 76 137 155
Valuation, ×
Valuation, × P/E — — — — — — — — — —
P/S — — — — — — — — — —
P/B — — — — — — — — — —
EV/Sales — — — — — — — — — —
EV/FCF — — — — — — — — — —
Cash, $m
Cash, $m Operating cash flow — (19) (17) (28) (53) (106) (116) (121) (118) (186)
Capex — (1) 0 0 0 (2) (7) 0 0 0
Free cash flow — (19) (17) (29) (54) (108) (123) (121) (118) (186)
Balance, $m
Balance, $m Working capital — 2 42 40 343 226 226 246 286 200
Total debt — 49 107 — — 35 33 — — —
Net debt — 46 (44) (44) (351) (243) (243) (260) (312) (238)
Shareholders’ equity — (46) (64) (100) 344 232 231 251 293 212
Returns, %
Returns, % ROA — (67.16) (76.76) (78.08) (34.66) (40.54) (49.62) (46.07) (42.67) (66.45)
ROIC — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
ROE — 34.04 33.47 46.49 (57.69) (45.24) (61.30) (55.73) (50.84) (82.63)
Negative figures in brackets.

All 10 years →

Charts ten years each

Annexon, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
ANL Adlai Nortye Ltd. Sponsored ADR $710.1M — — — — +46.03% (above 0%: growing) — — Compare
OABI OmniAb, Inc. $687.7M — (loss-making) — (loss-making) +244.24% (above 0%: growing) n/m +211.16% (above 0%: growing) 95.45% (49.47%) Compare
ANNX Annexon, Inc. $682.5M — (loss-making) — — n/m −26.41% (below 0%: shrinking) 0.00% 0.00%
MDXG MiMedx Group, Inc $682.2M 111× — (loss-making) −34.73% (below 0%: shrinking) n/m −174.83% (below 0%: shrinking) 68.96% (28.69%) Compare
CADL Candel Therapeutics, Inc. $681.8M — (loss-making) — (loss-making) 0.00% n/m −93.35% (below 0%: shrinking) 0.00% 0.00% Compare
PHAR Pharming Group N.V. Sponsored ADR $681.6M 62.4× — (loss-making) −3.22% (below 0%: shrinking) −57.14% (below 0%: shrinking) −183.87% (below 0%: shrinking) 83.92% 1.44% Compare
GYRE Gyre Therapeutics, Inc. $678.6M — (loss-making) — (loss-making) −2.12% (below 0%: shrinking) n/m −130.45% (below 0%: shrinking) 92.41% (49.35%) Compare
AURA Aura Biosciences, Inc. $657.5M — (loss-making) — — n/m −56.26% (below 0%: shrinking) 0.00% 0.00% Compare
DSGN Design Therapeutics, Inc. $655.9M — (loss-making) — (loss-making) — n/m −7.00% (below 0%: shrinking) 0.00% 0.00% Compare
Median of peers $681.7M — — −2.12% — −74.80% 68.96% 0.00%

All 614 Biotechnology stocks →

Annexon, Inc. (ANNX) key facts

  • Concern: Annexon, Inc. reported a net loss of $206.7 million, or a loss of $1.34 per share, for fiscal 2025.
  • Annexon, Inc. (ANNX) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, ANNX traded at $3.41, a market capitalization of $682.5 million.
  • Return on equity was −82.6% and debt-to-equity 0.00.

Source: company filings (standardised) and stockrow calculations.

Annexon, Inc. (ANNX) Latest News

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