Alnylam Pharmaceuticals, Inc.

ALNY Healthcare Biotechnology

Alnylam Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $3.7 billion, up 65.2% from fiscal 2024. In the quarter to June 2026, revenue grew 66.9%, EPS grew 341.2%, free cash flow grew 152.8% and total debt fell 1.51%, each against the same quarter a year earlier. Member of the Nasdaq 100; revenue growth for five consecutive years.

231.83 2.20 −0.94%
Market cap
$31.3B
P/E
39.5×
Fwd P/E
39.6×
Dividend yield
—
F-score
6/9
Altman Z
7.30
Beneish M
−1.95
Dividend safety
n/a
Dec '16 Dec '17 Dec '18 Dec '19 Dec '20 Dec '21 Dec '22 Dec '23 Dec '24 Dec '25
Piotroski F-Score
2 5 2 2 4 3 3 5 5 6
P/E ratio
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 163.12
P/S ratio
70.13 132.79 97.91 57.26 30.32 23.79 27.40 13.32 13.36 14.03
Altman Z-Score
3.22 28.92 12.72 5.20 1.92 2.14 2.30 1.84 2.90 7.30
Altman Z″-Score (non-manufacturers)
(0.91) 8.26 (0.09) (2.40) (1.67) (2.17) (4.01) (3.07) (2.60) (0.11)
P/FCF ratio
0.00 0.00 0.00 0.00 0.00 0.00 0.00 580.47 0.00 111.94
P/Operating CF
(42.22) (115.87) (48.74) (64.21) (121.36) (133.79) (215.38) (817.18) (317.31) 318.51
Beneish M-Score
(2.03) (2.25) (3.71) (1.52) 3.21 (3.03) (3.07) (2.66) (2.50) (1.95)
P/B ratio
3.59 6.76 5.63 8.75 14.71 34.15 0.00 0.00 447.73 66.01
EV/Sales
60.02 114.32 83.83 51.53 26.91 21.71 26.27 12.54 12.62 13.51
EV/EBITDA
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 90.08
EV/FCF
(7.60) (21.11) (9.11) (27.05) (19.35) (25.52) (44.43) 546.65 (666.08) 107.85
Current Ratio
5.10 12.23 6.69 4.87 4.47 4.04 3.51 3.08 2.78 2.76
Net Debt/EBITDA
1.16 3.40 1.32 1.42 2.23 2.84 1.59 6.22 13.89 (3.41)
Debt/Equity
0.16 0.02 0.02 0.19 0.19 1.15 (6.43) (4.63) 15.27 1.28
ROE
(37.54%) (36.54%) (49.63%) (64.66%) (69.92%) (106.31%) (526.14%) 232.40% 362.29% 73.28%
ROA
(30.96%) (30.14%) (42.67%) (44.64%) (29.58%) (24.19%) (31.47%) (11.94%) (6.89%) 6.82%
ROIC
(59.85%) (295.38%) (205.47%) (328.88%) 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Return on Tangible Assets
(62.64%) (27.23%) (56.75%) (49.55%) (34.41%) (32.61%) (46.21%) (17.33%) (10.65%) 10.13%
Average Days of Receivables
180.60 138.03 91.41 71.44 446.14 85.85 83.72 65.44 65.80 76.42
Earnings Yield
(12.40%) (4.10%) (10.37%) (7.07%) (5.73%) (4.25%) (3.98%) (1.81%) (0.92%) 0.61%
Free Cash Flow Yield
(11.26%) (4.08%) (9.40%) (3.33%) (4.59%) (3.57%) (2.16%) 0.17% (0.14%) 0.89%
Free Cash Flow per Share
(4.35) (5.38) (6.85) (3.83) (5.96) (6.06) (5.04) 0.34 (0.33) 3.55
Book value per Share
10.75 19.51 12.94 13.17 8.84 4.97 (1.30) (1.77) 0.53 6.02
Free Cash Flow
(372.26) (486.99) (689.50) (418.58) (685.32) (718.06) (613.33) 41.95 (42.59) 465.38
EV/EBIT
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 100.07
Other line items

Show all line items

Columns are period end dates