Agios Pharmaceuticals, Inc.
AGIO Healthcare Biotechnology
Agios Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $54.0 million, up 48.0% from fiscal 2024. In the quarter to June 2026, revenue grew 259.3%, EPS grew 12.4% and free cash flow grew 25.0%, each against the same quarter a year earlier. Revenue growth for three consecutive years.
Follow AGIO
Agios Pharmaceuticals, Inc. (AGIO) Piotroski F-score
Agios Pharmaceuticals, Inc.'s Piotroski F-score for fiscal 2025 is 3 out of 9: 3 of nine tests of profitability, leverage and efficiency passed, down from 4 in fiscal 2024.
Piotroski F-score, annual
Embed this chart
Annual newest first
| Period | Piotroski F-score | Change (points) |
|---|---|---|
| FY2025 | 3 | (1.00) |
| FY2024 | 4 | (1.00) |
| FY2020 | 5 | 2.00 |
| FY2019 | 3 | (2.00) |
| FY2018 | 5 | 3.00 |
| FY2017 | 2 | (2.00) |
| FY2016 | 4 | — |
How fiscal 2025’s score is made up
| Test | This year | Year before | Result | Points |
|---|---|---|---|---|
| Positive return on assets | (27.89%) | 51.82% | Fail | 0 |
| Positive operating cash flow | (372.98m) | (389.84m) | Fail | 0 |
| Rising return on assets | (27.89%) | 51.82% | Fail | 0 |
| Cash flow above net income | 39.80m | (1.06b) | Pass | 1 |
| Falling long-term leverage | 0.00 | 0.00 | Pass | 1 |
| Rising current ratio | 11.46 | 11.90 | Fail | 0 |
| No new shares issued | 57,972,000 | 56,807,400 | Fail | 0 |
| Rising gross margin | 88.26% | 88.59% | Fail | 0 |
| Rising asset turnover | 0.04 | 0.03 | Pass | 1 |
| Piotroski F-score | Weak — most fundamentals deteriorated | 3 | ||
How the Piotroski F-score works
One point for each of nine tests, this fiscal year against the one before: positive return on assets, positive operating cash flow, rising return on assets, cash flow above net income, falling long-term leverage, a rising current ratio, no new shares issued, a rising gross margin and rising asset turnover. The ratios are the ones on this site, so each can be checked.
Joseph Piotroski (2000) called 8–9 high and 0–1 low; reading it in three bands is the common convention:
| 7–9 | Strong — most fundamentals improved |
|---|---|
| 4–6 | Mixed |
| 0–3 | Weak — most fundamentals deteriorated |
Where this differs from the paper: return on assets is on average rather than beginning-of-year assets, and weighted basic shares stand in for shares issued. The score is shown only when all nine tests can be worked out, which takes three fiscal years; banks and insurers, which report no current assets or gross profit, have none.
Piotroski F-score against peers
| Company | Piotroski F-score |
|---|---|
| ZYME Zymeworks Inc. compare | 7 |
| LKFT Lakefront Biotherapeutics - Sponsored ADR compare | 6 |
| MESO Mesoblast Limited compare | 5 |
| IMNM Immunome, Inc. compare | 4 |
| SRPT Sarepta Therapeutics, Inc. compare | 3 |
| AGIO Agios Pharmaceuticals, Inc. | 3 |
| PVLA Palvella Therapeutics, Inc. compare | 2 |
| MRVI Maravai LifeSciences Holdings, Inc. compare | 2 |
| MLYS Mineralys Therapeutics, Inc. compare | — |
What Piotroski F-score is
The Piotroski F-Score tells an investor how many signs of improving profitability, funding and efficiency a company shows against a year earlier.
One point for each of nine tests against a year earlier: positive return on assets, positive operating cash flow, rising return on assets, cash flow above net income, falling long-term leverage, rising current ratio, no new shares issued, rising gross margin, and rising asset turnover