Sunday 18 October 2026
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Agenus Inc.
AGEN Healthcare Biotechnology
Agenus Inc.’s revenue for fiscal 2025 (year ended December 2025) was $114.2 million, up 10.4% from fiscal 2024. In the quarter to June 2026, revenue grew 34.4%, EPS grew 98.6%, free cash flow fell 55.3% and total debt fell 11.2%, each against the same quarter a year earlier.
6.04
0.64
−9.58%
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Target Price Range
Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Trend | 2026e | 2027e | 2028e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Price, $ | |||||||||||||||
| Price, $ | Low | 51.23 | 62.81 | 30.23 | 41.81 | 35.72 | 49.07 | 24.53 | 12.20 | 2.50 | 1.38 |
Analyst estimates 2026–2028 Powerpack |
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| High | 147.01 | 106.97 | 121.49 | 89.70 | 110.50 | 133.27 | 68.50 | 60.26 | 19.69 | 7.34 | |||||
| People | |||||||||||||||
| People | Employees | 255 | 255 | 294 | 328 | 359 | 441 | 533 | 389 | 316 | 81 | ||||
| Revenue/emp, $m | 0.09 | 0.17 | 0.13 | 0.46 | 0.25 | 0.67 | 0.18 | 0.40 | 0.33 | 1.41 | |||||
| Income, $m | |||||||||||||||
| Income, $m | Revenue | 23 | 43 | 37 | 150 | 88 | 296 | 98 | 156 | 103 | 114 | ||||
| Gross margin, % | 100.00 | 100.00 | 100.00 | 100.00 | 97.34 | 98.83 | 89.22 | 98.01 | 99.53 | 99.11 | |||||
| EBT | (127) | (121) | (162) | (112) | (183) | (29) | (231) | (257) | (232) | (3) | |||||
| EBT margin, % | (562.59) | (281.48) | (440.53) | (74.35) | (207.43) | (9.72) | (235.31) | (164.69) | (224.50) | (2.70) | |||||
| Net income | (127) | (121) | (162) | (112) | (183) | (29) | (231) | (257) | (232) | (3) | |||||
| Depreciation | 5 | 6 | 6 | 7 | 7 | 7 | 7 | 14 | 13 | 10 | |||||
| Per share, $ | |||||||||||||||
| Per share, $ | Revenue | 5.19 | 8.71 | 6.64 | 22.23 | 10.22 | 25.83 | 6.96 | 8.74 | 4.82 | 3.84 | ||||
| Earnings | (29.20) | (24.60) | (28.80) | (16.00) | (21.00) | (2.20) | (15.60) | (13.80) | (10.59) | 0.00 | |||||
| Cash flow | (18.37) | (19.15) | (23.67) | (2.77) | (16.13) | 0.89 | (12.45) | (12.53) | (7.37) | (2.60) | |||||
| Capex | (2.88) | (0.61) | (0.65) | (0.69) | (0.40) | (2.46) | (2.21) | (0.37) | (0.03) | 0.01 | |||||
| Free cash flow | (21.24) | (19.76) | (24.32) | (3.46) | (16.53) | (1.57) | (14.65) | (12.90) | (7.40) | (2.58) | |||||
| Book value | (8.99) | (15.41) | (31.51) | (34.28) | (24.52) | 4.19 | (3.90) | (8.29) | (14.27) | (9.34) | |||||
| Shares, m | 4 | 5 | 6 | 7 | 9 | 11 | 14 | 18 | 21 | 30 | |||||
| Valuation, × | |||||||||||||||
| Valuation, × | P/E | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||
| P/S | 15.75 | 7.97 | 7.03 | 3.59 | 6.11 | 2.45 | 6.77 | 1.83 | 0.57 | 0.82 | |||||
| P/B | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 15.10 | 0.00 | 0.00 | 0.00 | 0.00 | |||||
| EV/Sales | 18.15 | 10.37 | 5.95 | 3.27 | 5.20 | 1.45 | 4.93 | 1.43 | 0.50 | 1.39 | |||||
| EV/FCF | (4.43) | (4.57) | (1.63) | (21.05) | (3.21) | (23.87) | (2.34) | (0.97) | (0.32) | (2.06) | |||||
| Cash, $m | |||||||||||||||
| Cash, $m | Operating cash flow | (80) | (94) | (131) | (19) | (139) | 10 | (175) | (224) | (158) | (77) | ||||
| Capex | (13) | (3) | (4) | (5) | (3) | (28) | (31) | (7) | (1) | 0 | |||||
| Free cash flow | (92) | (97) | (135) | (23) | (143) | (18) | (206) | (231) | (159) | (77) | |||||
| Balance, $m | |||||||||||||||
| Balance, $m | Working capital | 50 | 17 | 7 | (36) | (16) | 175 | 24 | (143) | (176) | (190) | ||||
| Total debt | 131 | 163 | 13 | 14 | 20 | 14 | 13 | 13 | 33 | 45 | |||||
| Net debt | 54 | 103 | (40) | (48) | (80) | (293) | (180) | (63) | (7) | 42 | |||||
| Shareholders’ equity | (39) | (76) | (175) | (231) | (211) | 48 | (55) | (148) | (306) | (278) | |||||
| Returns, % | |||||||||||||||
| Returns, % | ROA | (63.72) | (81.86) | (116.37) | (73.95) | (97.94) | (7.09) | (50.09) | (67.62) | (84.20) | (0.04) | ||||
| ROIC | (444.11) | (240.08) | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |||||
| ROE | (805.04) | 210.36 | 127.73 | 53.15 | 81.80 | 29.51 | 6,300.19 | 242.00 | 100.01 | 0.03 | |||||
Negative figures in brackets.
Fiscal years to Dec 2025 · latest quarter Jun 2026
Charts ten years each
Agenus Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| CYPH Cypherpunk Technologies Inc. | $325.5M | 4.4× | — (loss-making) | 0.00% | n/m | +15.53% (above 0%: growing) | 0.00% | 0.00% | Compare |
| ARCT Arcturus Therapeutics Holdings Inc. | $320.3M | — (loss-making) | — (loss-making) | −89.54% (below 0%: shrinking) | n/m | −245.65% (below 0%: shrinking) | 100.00% | (863.30%) | Compare |
| AGEN Agenus Inc. | $301.7M | 2.3× | 4.1× | +34.36% (above 0%: growing) | n/m | −55.25% (below 0%: shrinking) | 100.00% | 32.72% | |
| CTNM Contineum Therapeutics, Inc. | $297.2M | — (loss-making) | — | — | n/m | +26.73% (above 0%: growing) | 100.00% | 0.00% | Compare |
| ARTV Artiva Biotherapeutics, Inc. | $296.3M | — (loss-making) | — (loss-making) | — | n/m | +13.60% (above 0%: growing) | 100.00% | 0.00% | Compare |
| BNTC Benitec Biopharma Limited | $295.1M | — (loss-making) | — (loss-making) | −85.42% (below 0%: shrinking) | n/m | +38.90% (above 0%: growing) | 0.00% | 0.00% | Compare |
| SRZN Surrozen, Inc. | $294.7M | — (loss-making) | — (loss-making) | +408.65% (above 0%: growing) | n/m | −21.25% (below 0%: shrinking) | 100.00% | (207.40%) | Compare |
| FULC Fulcrum Therapeutics, Inc. | $280.0M | — (loss-making) | — (loss-making) | +27,018.64% (above 0%: growing) | n/m | −13.05% (below 0%: shrinking) | 100.00% | 0.00% | Compare |
| OCGN Ocugen, Inc. | $275.9M | — (loss-making) | — (loss-making) | +8.38% (above 0%: growing) | n/m | −13.42% (below 0%: shrinking) | 100.00% | (1,105.11%) | Compare |
| Median of peers | $295.7M | — | — | +4.19% | — | +0.28% | 100.00% | 0.00% |
Agenus Inc. (AGEN) key facts
- Strength: Agenus Inc.’s revenue for fiscal 2025 (year ended December 2025) was $114.2 million, up 10.4% from fiscal 2024.
- Agenus Inc. (AGEN) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
- As of October 16, 2026, AGEN traded at $6.04, a market capitalization of $301.7 million.
- Return on equity was 0.03% and debt-to-equity -0.15.
- Its Piotroski F-score is 4 out of 9 and its Altman Z-score is −14.16 (distress zone) for fiscal 2025.