Saturday 17 October 2026
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Aclaris Therapeutics, Inc.
ACRS Healthcare Biotechnology
Aclaris Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $7.8 million, down 58.2% from fiscal 2024. In the quarter to June 2026, revenue fell 8.33%, EPS fell 15.4% and free cash flow fell 98.8%, each against the same quarter a year earlier.
3.28
0.21
−6.02%
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Target Price Range
Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Trend | 2026e | 2027e | 2028e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Price, $ | |||||||||||||||
| Price, $ | Low | 14.12 | 21.32 | 6.15 | 0.74 | 0.70 | 5.65 | 9.26 | 0.59 | 0.86 | 1.05 |
Analyst estimates 2026–2028 Powerpack |
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| High | 31.80 | 33.25 | 26.25 | 8.19 | 7.95 | 30.38 | 18.96 | 18.54 | 5.17 | 3.48 | |||||
| People | |||||||||||||||
| People | Employees | 31 | 96 | 169 | 77 | 60 | 77 | 105 | 91 | 64 | 73 | ||||
| Revenue/emp, $m | 0.00 | 0.02 | 0.04 | 0.05 | 0.11 | 0.09 | 0.28 | 0.34 | 0.29 | 0.11 | |||||
| Income, $m | |||||||||||||||
| Income, $m | Revenue | — | 2 | 6 | 4 | 6 | 7 | 30 | 31 | 19 | 8 | ||||
| Gross margin, % | 0.00 | 28.28 | 29.62 | 4.07 | 20.81 | 30.29 | 59.80 | 42.14 | 17.43 | 6.93 | |||||
| EBT | (48) | (70) | (82) | (114) | (51) | (91) | (87) | (89) | (132) | (65) | |||||
| EBT margin, % | 0.00 | (4,180.21) | (1,334.81) | (2,686.11) | (791.98) | (1,343.96) | (292.11) | (284.32) | (705.48) | (829.58) | |||||
| Net income | (48) | (69) | (133) | (161) | (51) | (91) | (87) | (88) | (132) | (65) | |||||
| Depreciation | 0 | 0 | 2 | 25 | 1 | 1 | 1 | 1 | 1 | 0 | |||||
| Per share, $ | |||||||||||||||
| Per share, $ | Revenue | 0.00 | 0.06 | 0.19 | 0.10 | 0.15 | 0.12 | 0.46 | 0.45 | 0.24 | 0.06 | ||||
| Earnings | (2.25) | (2.44) | (4.03) | (3.90) | (1.20) | (1.60) | (1.33) | (1.27) | (1.71) | (0.53) | |||||
| Cash flow | (1.62) | (1.95) | (3.06) | (2.33) | (0.91) | (0.92) | (1.04) | (1.12) | (0.26) | (0.38) | |||||
| Capex | (0.01) | (0.04) | (0.04) | (0.04) | (0.01) | (0.01) | (0.01) | (0.02) | (0.46) | 0.00 | |||||
| Free cash flow | (1.63) | (1.99) | (3.10) | (2.37) | (0.92) | (0.92) | (1.05) | (1.14) | (0.72) | (0.39) | |||||
| Book value | 7.91 | 8.02 | 6.54 | 1.69 | 0.89 | 3.48 | 3.03 | 2.25 | 2.01 | 0.84 | |||||
| Shares, m | 21 | 28 | 33 | 41 | 43 | 57 | 65 | 70 | 77 | 123 | |||||
| Valuation, × | |||||||||||||||
| Valuation, × | P/E | — | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||
| P/S | — | 0.00 | 37.28 | 18.51 | 42.46 | 122.00 | 33.03 | 2.35 | 10.24 | 47.14 | |||||
| P/B | — | 3.12 | 1.33 | 1.12 | 7.31 | 4.18 | 4.97 | 0.47 | 1.23 | 3.58 | |||||
| EV/Sales | — | 0.00 | 19.31 | 1.61 | 35.75 | 95.28 | 26.08 | (1.12) | 4.75 | 36.92 | |||||
| EV/FCF | — | (9.12) | (1.45) | (0.07) | (5.93) | (12.28) | (11.38) | 0.44 | (4.40) | (6.12) | |||||
| Cash, $m | |||||||||||||||
| Cash, $m | Operating cash flow | (35) | (55) | (101) | (96) | (39) | (52) | (68) | (78) | (20) | (47) | ||||
| Capex | 0 | (1) | (1) | (2) | 0 | 0 | (1) | (1) | (36) | 0 | |||||
| Free cash flow | (35) | (56) | (102) | (98) | (39) | (52) | (68) | (80) | (56) | (47) | |||||
| Balance, $m | |||||||||||||||
| Balance, $m | Working capital | 132 | 187 | 152 | 61 | 43 | 182 | 210 | 98 | 94 | 68 | ||||
| Total debt | — | — | 30 | 4 | 11 | 2 | 2 | — | — | — | |||||
| Net debt | (137) | (194) | (138) | (71) | (43) | (191) | (218) | (119) | (114) | (91) | |||||
| Shareholders’ equity | 169 | 225 | 215 | 70 | 38 | 197 | 198 | 157 | 156 | 103 | |||||
| Returns, % | |||||||||||||||
| Returns, % | ROA | (35.59) | (32.66) | (51.14) | (86.32) | (60.34) | (56.44) | (34.36) | (39.15) | (63.23) | (34.10) | ||||
| ROIC | (94.07) | (108.19) | (68.76) | 0.00 | 0.00 | (946.13) | 0.00 | (159.82) | (211.41) | (387.11) | |||||
| ROE | (36.70) | (34.72) | (60.28) | (113.22) | (94.86) | (77.34) | (44.01) | (49.88) | (84.46) | (50.20) | |||||
Negative figures in brackets.
Fiscal years to Dec 2025 · latest quarter Jun 2026
Charts ten years each
Aclaris Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| VECT VectivBio Holding AG | $545.5M | — (loss-making) | — (loss-making) | — | n/m | — | 91.93% | 0.00% | Compare |
| PBYI Puma Biotechnology, Inc. | $543.0M | 18.2× | 24.2× | +7.75% (above 0%: growing) | +33.33% (above 0%: growing) | −88.45% (below 0%: shrinking) | 77.92% | 13.42% | Compare |
| DRUG Bright Minds Biosciences Inc. | $534.7M | — (loss-making) | — | — | n/m | −124.63% (below 0%: shrinking) | 0.00% | 0.00% | Compare |
| FTH Faeth Therapeutics, Inc. | $532.3M | — (loss-making) | — | — | n/m | −174.24% (below 0%: shrinking) | 0.00% | 0.00% | Compare |
| CTMX CytomX Therapeutics, Inc. | $525.1M | — (loss-making) | — (loss-making) | −92.40% (below 0%: shrinking) | n/m | −14.50% (below 0%: shrinking) | 100.00% | (1,677.08%) | Compare |
| CYVNY Ceryvyn Therapeutics Ltd. - Unsponsored ADR | $524.8M | — (loss-making) | — (loss-making) | −7.53% (below 0%: shrinking) | n/m | −31.52% (below 0%: shrinking) | 0.00% | 0.00% | Compare |
| ACRS Aclaris Therapeutics, Inc. | $513.7M | — (loss-making) | — (loss-making) | −8.33% (below 0%: shrinking) | n/m | −98.77% (below 0%: shrinking) | 10.80% | (1,487.91%) | |
| MNPR Monopar Therapeutics Inc. | $481.9M | — (loss-making) | — | — | n/m | −201.41% (below 0%: shrinking) | — | 0.00% | Compare |
| ENTX Entera Bio Ltd. | $481.5M | — (loss-making) | — (loss-making) | +200.00% (above 0%: growing) | n/m | −108.86% (below 0%: shrinking) | 0.00% | 0.00% | Compare |
| Median of peers | $528.7M | — | — | +0.11% | — | −108.86% | 0.00% | 0.00% |
Aclaris Therapeutics, Inc. (ACRS) key facts
- Concern: Aclaris Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $7.8 million, down 58.2% from fiscal 2024.
- Aclaris Therapeutics, Inc. (ACRS) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
- As of October 16, 2026, ACRS traded at $3.28, a market capitalization of $513.7 million.
- Return on equity was −50.2% and debt-to-equity 0.00.
- Its Piotroski F-score is 3 out of 9 and its Altman Z-score is −5.60 (distress zone) for fiscal 2025.