Alumis Inc. ALMS

7.10 (0.19) (2.61%) as of 25 Sep
Market cap
$985.9M
P/E
0.0×
Insider Buys alert about insiders buying in the last 12 month

Insider Decisions

Total buys 61.68
Total sells 1.55
in millions of $
Nov 25 Feb 26 May 26 Aug 26
Buy — 10 2 4 — — — — — — — 1
Sell — — — — — — — — — 1 6 1
Insider Ownership 25.30%

Capital & Financial Ratios

Market Cap 985.86
Revenue 7.40
Net Income (438.96)
Free Cash Flow (351.80)
Net Debt (502.29)
Current Ratio 6.74
Debt/Equity 0.00
P/E ratio 0.00
P/S ratio 122.55
P/B ratio 2.01
Past 5Y EPS Growth —
This Y EPS Growth (14.16%)
Next Y EPS Growth 13.66%
Next 5Y EPS Growth 10.01%
in millions of $

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —

Assets vs Liabilities

2023 2024 2025 Q'26
Cash 49 288 309 502
Receivables — — — —
Inventory — — — —
Other — — — —
53 306 318 514
2023 2024 2025 Q'26
Payables 1 10 10 13
ST’ Debt — — — —
Other — — — —
21 51 73 76
in millions of $

Compound Annual Growth

10y 5y 3y
Sales — — —
Cash Flow — — —
Earnings — — —
Book Value — — —

Revenue

Mar Jun Sep Dec Year
’26 2 2 — — —
in millions of $ · fiscal quarters ending in the months shown

Operating Cash Flow

Mar Jun Sep Dec Year
’26 (87) (81) — — —
’25 (80) (106) (111) (72) (370)
’24 (44) (52) (84) (75) (255)
in millions of $ · fiscal quarters ending in the months shown

Free Cash Flow

Mar Jun Sep Dec Year
’26 (87) (82) — — —
’25 (80) (107) (111) (72) (370)
’24 (44) (53) (85) (75) (257)
in millions of $ · fiscal quarters ending in the months shown

EPS

Mar Jun Sep Dec Year
’26 (0.74) (1.11) — — —
’25 (1.82) 0.77 (1.06) (0.95) (2.86)
’24 (21.03) (23.10) (1.73) 35.49 (10.38)
fiscal quarters ending in the months shown

Target Price Range

Analyst price targets

Recommendation Rating

1.3
1Buy 2 3Hold 4 5Sell
2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028
— — — — — — — — 7.46 2.76

Analyst estimates 2026–2028

Powerpack
Low Price
— — — — — — — — 13.53 12.44
High Price
— — — — — — — 109 170 224
Employees
— — — — — — — 0 0 0
Revenue/Emp
— — — — — — — — — 24
Revenue
— — — — — — — — — 100.00%
Gross Margin
— — — — — — — (155) (294) (252)
EBT
— — — — — — — 0.00% 0.00% (1,047.34%)
EBT Margin
— — — — — — — (155) (294) (243)
Net Income
— — — — — — — 1 3 3
Depreciation
— — — — — — — 0.00 0.00 0.28
Revenue/Sh
— — — — — — — (72.08) (10.38) (2.86)
Earnings/Sh
— — — — — — — (60.45) (9.00) (4.35)
Cash Flow/Sh
— — — — — — — (2.09) (0.06) (0.01)
Capex/Sh
— — — — — — — (62.54) (9.06) (4.35)
Free CF/Sh
— — — — — — — (157.78) 9.18 3.54
Book Value/Sh
— — — — — — — 2 28 85
Shares
— — — — — — — — — 0.00
PE Ratio
— — — — — — — — — 34.51
PS Ratio
— — — — — — — — — 2.75
PB Ratio
— — — — — — — — — 21.68
EV/Sales
— — — — — — — — — (1.41)
EV/FCF
— — — — — — — (130) (255) (370)
Op' Cash Flow
— — — — — — — (4) (2) (1)
Capex
— — — — — — — (134) (257) (370)
FCF
— — — — — — — 32 255 245
Working Cap'
— — — — — — — — — —
Total Debt
— — — — — — — (49) (288) (309)
Net Debt
— — — — — — — (339) 260 301
Sh' Equity
— — — — — — — 0.00% (136.66%) (64.63%)
ROA
— — — — — — — 0.00% 0.00% 0.00%
ROIC
— — — — — — — 0.00% 743.43% (86.68%)
ROE
predictions in italic, sparklines do not include predictions

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Alumis Inc. (ALMS) key facts

  • Alumis Inc. (ALMS) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • Alumis Inc.’s revenue for fiscal 2025 (year ended December 2025) was $24.1 million.
  • As of September 25, 2026, ALMS traded at $7.10, a market capitalization of $985.9 million.
  • Return on equity was −86.7% and debt-to-equity 0.00.

Source: company filings (standardised) and stockrow calculations.

Alumis Inc. (ALMS) Latest News

News by impact score

Fine-tune

8 Sep

3

Alumis plans to advance Envudeucitinib after LUMUS missed in the overall population. Missed overall population endpoint creates mixed development signal with limited trajectory shift.

3 Sep

5

Alumis Inc. (ALMS) lead lupus drug missed Phase 2b trial endpoints. Lead lupus drug missing Phase 2b endpoints threatens Alumis Inc. entire development pipeline and viability.

4

Alumis shares dropped 56.2% on mixed Phase 2b lupus trial data that spotlight biomarker strategy for future patient selection. Mixed Phase 2b lupus results produced a 56% stock drop and directly threaten Alumis lead asset prospects.

4

Alumis Inc. (ALMS) lupus trial missed, leaving shares looking overvalued despite 3x price-to-book ratio. Lupus trial miss directly hits lead asset and raises valuation concerns at 3x P/B.

1 Sep

5

Alumis Inc. shares plunged 57 percent in a single session for the stock's worst day, driven by heavy selloff from undisclosed factors. 57 percent single-day plunge signals events capable of fundamentally redefining Alumis Inc. market position and long-term outlook.

5

Alumis Inc. lupus drug trial failed, resulting in 58% stock price decline. Failed lupus drug removes core pipeline asset and causes 58% market cap loss.

4

Alumis lupus trial missed primary endpoints but indicated promise in high-interferon subgroup. Missed primary endpoints in key lupus trial likely pressures development timeline and investor sentiment.

4

Alumis Inc. Phase 2b lupus trial missed primary and secondary endpoints. Missed Phase 2b lupus endpoints represent major setback to pipeline progress and stock valuation.

4

Alumis Inc. announced topline results from its Envudeucitinib Phase 2b trial in systemic lupus erythematosus. Phase 2b results for Envudeucitinib directly affect Alumis Inc. valuation, development timeline and investor sentiment.

4

Alumis Inc.'s TYK2 drug failed in a key lupus study. TYK2 drug failure in pivotal lupus study undermines Alumis' lead asset and long-term prospects.

13 Aug

3

Alumis Inc. reported second quarter 2026 financial results and highlighted recent achievements. Quarterly financial results and achievement updates typically deliver moderate influence on near-term sentiment without fundamentally shifting long-term trajectory.

10 Aug

4

Alumis Inc. reports long-term data for Envudeucitinib showing the highest PASI 100 skin clearance among oral therapies for plaque psoriasis, positioning the treatment to set a new standard. Superior long-term efficacy data for Envudeucitinib strengthens Alumis competitive position in the psoriasis market.

29 May

3

Alumis (ALMS) maintains strong analyst sentiment after reporting Q1 results and advancing its Envudeucitinib pipeline. Q1 results and pipeline progress provide moderately positive signals for Alumis operations and sentiment but lack evidence of major trajectory shifts.

24 May

3

Alumis Inc. (ALMS) stock rose 355%. One fund established a $169 million position last quarter. Large institutional stake and sharp share-price gain reflect increased investor interest without altering core operations or long-term trajectory.

20 May

3

Alumis Inc. may sacrifice short-term revenue to adopt a leaner, more focused business model. Strategic shift to leaner operations moderately affects Alumis revenue trajectory and positioning.

17 May

4

Alumis Inc. shares surged 400%. Cormorant Asset Management bought another $8 million worth of stock last quarter. 400% stock surge plus fresh $8 million institutional purchase signals major momentum shift for valuation and sentiment.

14 May

4

Alumis Inc. (ALMS) reported first quarter 2026 financial results and highlighted recent achievements. Quarterly financial results and achievement highlights directly impact investor sentiment, stock performance, and strategic outlook.

3

Alumis Inc. (ALMS) faces revenue drop but narrows net loss, prompting valuation analysis. Revenue decline offsets narrowed net loss, moderately affecting financial performance and investor sentiment.

6 Apr

4

Raymond James and Guggenheim analysts maintain bullish ratings on Alumis (ALMS) after positive trial results, highlighting the company's promising immunology pipeline and potential for long-term growth. Major analysts reaffirm bullish stances post-trial results, signaling significant boost to investor sentiment and ALMS stock trajectory.

4 Apr

4

Alumis (ALMS) shares dropped 5.8% despite positive Phase 3 data for its psoriasis treatment ESK-001 and plans to file an NDA in 2025, as investors reacted to mixed topline results, higher-than-expected adverse events, and a $344 million stock offering. Positive Phase 3 psoriasis data and NDA filing plans mark a significant regulatory milestone poised to drive long-term revenue potential despite short-term stock pressure.

3 Apr

5

Alumis (ALMS) announces positive Phase 3 results for Envudeucitinib in psoriasis, prompting a valuation reassessment amid potential path to approval and market entry. Positive Phase 3 results for Envudeucitinib in psoriasis position Alumis for regulatory approval, commercialization, and major revenue potential.

30 Mar

4

Oppenheimer describes Alumis' drug as 'very positive' for treating psoriasis and systemic lupus erythematosus. Oppenheimer's endorsement of Alumis' drug for major autoimmune diseases signals strong pipeline potential, likely driving significant investor interest and stock gains.

29 Mar

4

Alumis highlighted positive Phase III data for envudeucitinib in psoriasis, announced plans for NDA submission, and teased an upcoming lupus readout. Phase III success, NDA plans for psoriasis drug, and lupus readout teaser mark major milestones advancing Alumis' pipeline toward approvals.

28 Mar

5

Alumis’ Envudeucitinib delivered early and robust improvements in skin clearance, quality of life, and psoriasis symptoms in two Phase 3 trials, underscoring its potential as a leading oral therapy for plaque psoriasis. Strong Phase 3 topline data from two trials positions Envudeucitinib as a potential leading oral psoriasis therapy, fundamentally transforming Alumis' competitive position and long-term prospects.

19 Mar

4

Alumis Inc. (ALMS) reported year-end 2025 financial results and highlighted recent achievements. Year-end financial results combined with highlighted achievements represent major updates likely to influence investor sentiment and company trajectory.

18 Mar

4

Alumis announces late-breaker oral presentation of Phase 3 data for envudeucitinib in moderate-to-severe plaque psoriasis at the 2026 American Academy of Dermatology Annual Meeting. Late-breaker oral Phase 3 presentation signals strong efficacy data for envudeucitinib, likely driving significant investor enthusiasm and advancing Alumis toward regulatory approval.

10 Mar

4

Alumis presented TYK2 inhibitor catalysts at Leerink conference: positive Phase III psoriasis data, NDA submission plans, and upcoming lupus readout. Phase III psoriasis wins and NDA plans mark significant regulatory progress for Alumis' lead TYK2 asset.

26 Feb

4

Alumis Inc. (ALMS) presented Phase 3 trial details for its psoriasis drug and targets NDA filing in the second half of the year at the Oppenheimer Healthcare Conference. Phase 3 psoriasis data disclosure and H2 NDA filing target mark a critical step toward potential FDA approval and commercialization.

12 Feb

4

Alumis Inc. (ALMS) reported positive results from its Phase III trials for psoriasis treatments, highlighting the potential for a New Drug Application (NDA) submission in the near future. The company also discussed upcoming catalysts related to lupus treatments during the Guggenheim Summit, indicating a strategic focus on expanding its product pipeline and addressing unmet medical needs. Positive Phase III results and potential NDA submission could significantly enhance the company's market position and investor sentiment.

7 Feb

3

Alumis Inc. (ALMS) has experienced strong share price momentum over the past several months, prompting a valuation check. Analysts are assessing the sustainability of this growth and its implications for the company's future performance. Factors influencing the valuation include market trends, financial health, and competitive positioning within the industry. Investors are keenly observing how these elements will affect Alumis's trajectory moving forward. The strong share price momentum indicates a moderately noticeable influence on future performance and market sentiment.

stockrow.com/ALMS · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com