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Sana Biotechnology, Inc. SANA

Growth Flags show if company had growth for consecutive years

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Get access to target analyst prices, predictions, compound annual growth rates and more than four years of historical data.

Insider Decisions

in millions of $
Nov 25 Feb 26 May 26 Aug 26
Buy
Sell
Insider Ownership
36.82%

Capital & Financial Ratios

Market Cap
951.97
Revenue
Net Income
(211.82)
Free Cash Flow
(133.99)
Net Debt
(164.68)
Current Ratio
1.38
Debt/Equity
0.00
P/E ratio
0.00
P/S ratio
0.00
P/B ratio
5.93
Past 5Y EPS Growth
(10.60%)
This Y EPS Growth
28.65%
Next Y EPS Growth
13.71%
Next 5Y EPS Growth
14.37%
in millions of $

Dividends

Payout Ratio
0.00
Annual Dividend Rate
Annual Dividend Yield
total individual payouts
2025 ‡‡‡
2024 ‡‡‡
2023 ‡‡‡
2022 ‡‡‡
2021 ‡‡‡
predictions in italic, special payouts not included in total or ratios

Assets vs Liabilities

2023 2024 2025 Q'26
Cash 209.03 156.33 142.58 164.69
Receivables
Inventory
Other
213.52 160.81 148.68 170.63
2023 2024 2025 Q'26
Payables 4.11 5.21 1.67 1.36
ST’ Debt
Other 40.20 90.81
64.49 45.43 78.73 123.75
in millions of $

Compound Annual Growth

10y 5y 3y
Sales
Cash Flow ‡‡‡ ‡‡‡
Earnings ‡‡‡ ‡‡‡
Book Value ‡‡‡ ‡‡‡‡‡

Revenue

Year
in millions of $

Operating Cash Flow

Mar Jun Sep Dec Year
’26 (37.38) (32.79)
’25 (48.66) (33.10) (29.43) (32.64)
(143.83)
’24 (65.63) (58.54) (51.82) (47.16)
(223.15)
’23 (79.27) (58.80) (63.55) (51.96)
(253.58)
’22 (77.71) (71.48) (64.80) (76.07)
(290.05)
’21 (49.91) (40.56) (50.49) (110.10)
(251.05)
’20 (29.55) (33.37) (37.51) (37.56)
(137.98)
in millions of $

Free Cash Flow

Mar Jun Sep Dec Year
’26 (37.42) (34.39)
’25 (48.54) (32.61) (29.33) (32.85)
(143.33)
’24 (81.48) (71.60) (55.91) (47.60)
(256.58)
’23 (81.45) (60.38) (65.78) (66.00)
(273.61)
’22 (85.24) (75.87) (69.15) (80.67)
(310.93)
’21 (56.35) (50.71) (58.55) (115.30)
(280.92)
’20 (35.15) (36.06) (43.83) (46.82)
(161.85)
in millions of $

EPS

Mar Jun Sep Dec Year
’26 (0.17) (0.22)
’25 (0.21) (0.39) (0.16) (0.21)
(0.96)
’24 (0.49) (0.21) (0.25) (0.21)
(1.16)
’23 (0.43) (0.59) 0.00 (0.45)
(1.46)
’22 (0.17) (0.39) (0.45) (0.42)
(1.43)
’21 (1.52) 0.09 (0.46) (0.60)
(2.14)
’20 (7.40)
(21.92)

Target Price Range

High
‡‡‡‡‡
‡‡‡‡
Average
‡‡‡‡‡
‡‡‡
Low
‡‡‡‡‡
‡‡‡

Recommendation Rating

1.2
1
Buy
2
3
Hold
4
5
Sell
2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028
‡‡‡‡ 3.15 2.75 1.52 1.26
Low Price
‡‡‡‡ 16.04 8.01 12.00 7.30
High Price
‡‡‡‡‡ ‡‡‡‡‡ 421 328 194 142
Employees
‡‡‡ ‡‡‡ 0.00 0.00 0.00 0.00
Revenue/Emp
Revenue
‡‡‡ ‡‡‡ ‡‡‡ ‡‡‡ 0.00%
Gross Margin
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (269.48) (283.25) (266.76) (244.17)
EBT
‡‡‡ ‡‡‡ ‡‡‡ ‡‡‡ 0.00% 0.00% 0.00% 0.00% ‡‡‡ ‡‡‡ ‡‡‡
EBT Margin
‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (269.48) (283.25) (266.76) (244.17) ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡
Net Income
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 15.63 17.54 15.50 12.75
Depreciation
‡‡‡ ‡‡‡ ‡‡‡ ‡‡‡ 0.00 0.00 0.00 0.00 ‡‡‡ ‡‡‡ ‡‡‡
Revenue/Sh
‡‡‡‡‡ ‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (1.43) (1.46) (1.16) (0.96) ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡
Earnings/Sh
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (1.54) (1.30) (0.97) (0.57)
Cash Flow/Sh
‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (0.11) (0.10) (0.14) 0.00 ‡‡‡ ‡‡‡ ‡‡‡
Capex/Sh
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (1.65) (1.41) (1.11) (0.57)
Free CF/Sh
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 2.65 1.48 1.08 0.64
Book Value/Sh
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 188.34 194.54 230.89 253.23 ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡
Shares
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡
PE Ratio
‡‡‡ ‡‡‡ ‡‡‡
PS Ratio
‡‡‡ ‡‡‡ ‡‡‡
PB Ratio
EV/Sales
EV/FCF
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (290.05) (253.58) (223.15) (143.83) ‡‡‡ ‡‡‡ ‡‡‡
Op' Cash Flow
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (20.88) (20.03) (33.43) 0.49 ‡‡‡‡‡
Capex
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (310.93) (273.61) (256.58) (143.33)
FCF
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 332.93 149.03 115.38 69.95
Working Cap'
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 108.00
Total Debt
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (322.06) (209.03) (156.33) (142.58)
Net Debt
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 499.32 287.51 250.50 160.88
Sh' Equity
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (27.61%) (40.81%) (50.03%) (53.20%)
ROA
‡‡‡ ‡‡‡ ‡‡‡ ‡‡‡‡‡ (96.11%) (233.45%) (180.99%) (854.59%)
ROIC
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (43.90%) (72.00%) (99.17%) (118.70%)
ROE
predictions in italic, sparklines do not include predictions

Analyst Commentary (Summary)

Sana Biotechnology (SANA) embodies biotech’s brutal gamble: a clinical-stage cell therapy pioneer burning cash at an alarming rate with zero revenue since inception, ballooning losses from -$13 million in 2018 to -$357 million peaks, and relentless dilution exploding shares outstanding 4,600% to nearly 231 million. Despite a flashy SPAC debut in 2020 that saw shares hit $44, they’ve cratered over 90% amid pipeline pauses, manufacturing scandals, and a 54% workforce slash to 194 employees—classic signs of survival mode in a sector where 90% of players flame out.

Analysts peddle rosy targets implying 56-212% upside from depressed levels, banking on 2025’s projected $37 million revenue inflection and narrowing losses. But peel back the hype: negative ROE, ROIC, and Free Cash Flow per share scream capital destruction, with a fragile balance sheet (equity down 66% to $250 million) and just 1-2 years’ cash runway vulnerable to funding droughts. This isn’t undervaluation—it’s a ticking binary bomb where clinical wins could spark rebounds, but failures (like past hypoimmune halts) promise evaporation.

For contrarians eyeing the rubble, Sana tempts as a speculative lottery ticket, but the math favors caution: unproven milestones, persistent burn, and biotech M&A freeze demand a fortress margin of safety. Dive deeper for the full autopsy on whether this carcass revives or rots.

Sana Biotechnology, Inc. (SANA) Latest News

News by impact score

Fine-tune

10 Aug

3 , 4:05 PM
Sana Biotechnology released second quarter 2026 financial results and business updates. Quarterly financial results and business updates typically affect near-term investor views on operations and cash position.

16 Jul

4 , 5:11 PM
Sana Biotechnology publishes 14-month diabetes cell therapy results in NEJM. NEJM publication of 14-month cell therapy data marks major clinical milestone that can shift Sana's trajectory and investor sentiment.

13 Jul

4 , 8:00 AM
Sana Biotechnology released long-term NEJM data showing durable hypoimmune-modified islet cell transplants for Type 1 diabetes without immunosuppression. Publication of groundbreaking long-term clinical data on core hypoimmune platform advances commercialization prospects and investor sentiment.

15 May

3 GlobeNewswire, 9:00 AM
Sana Biotechnology, Inc. (SANA) sold approximately $69 million of shares through its at-the-market (ATM) facility. The $69 million share sale bolsters Sana Biotechnology's cash position for operations but introduces shareholder dilution with moderate financial impact.

12 May

4 GlobeNewswire, 4:05 PM
Sana Biotechnology presented preclinical data for SG293 surrogate, an in vivo CAR T cell therapy, demonstrating cell-specific delivery, potent CAR T cell generation, and deep B cell depletion in non-human primates. Positive preclinical NHP data for novel in vivo CAR T therapy advances Sana's pipeline and could significantly boost investor sentiment and competitive positioning.

11 May

3 GlobeNewswire, 4:05 PM
Sana Biotechnology reported first quarter 2026 financial results and business updates. Quarterly financial results and business updates moderately influence financial performance and investor sentiment without fundamentally altering long-term trajectory.

27 Apr

4 Insider Monkey, 2:22 AM
Sana Biotechnology (SANA) partners with Mayo Clinic to advance hypoimmune stem cell-derived islet cells for Type 1 diabetes treatment. Strategic collaboration with Mayo Clinic accelerates Sana's Type 1 diabetes cell therapy pipeline, boosting credibility and investor sentiment.

23 Apr

4 , 10:07 AM
Sana Biotechnology (SANA) valuation assessed after announcing partnership with Mayo Clinic and receiving equity investment. Mayo Clinic partnership and equity investment deliver strategic validation, additional funding, and boosted investor sentiment for SANA.

14 Apr

4 Insider Monkey, 5:50 AM
Sana Biotechnology Inc. (SANA) achieves new milestone in cell therapy development for Type 1 Diabetes. Milestone in Type 1 Diabetes cell therapy advances SANA's core pipeline significantly, boosting investor sentiment and trajectory.

13 Apr

4 GlobeNewswire, 4:05 PM
Sana Biotechnology and Mayo Clinic announce strategic collaboration to improve Type 1 diabetes care and accelerate development of hypoimmune islet cell therapy SC451. Strategic partnership with Mayo Clinic accelerates SC451 development for Type 1 diabetes, enhancing Sana's pipeline progress and market positioning.

13 Mar

5 GlobeNewswire, 9:00 AM
Sana Biotechnology announces continued positive clinical results through 14 months from Type 1 Diabetes study of islet cell transplantation without immunosuppression. 14-month positive data from immunosuppression-free islet cell transplants for Type 1 Diabetes could transform Sana's competitive position in stem cell therapies.

3 Mar

4 GlobeNewswire, 4:05 PM
Sana Biotechnology reported fourth quarter and full year 2025 financial results and business updates. Quarterly and annual financial results with business updates significantly influence investor sentiment and stock trajectory.

3 Associated Press Finance, 4:39 PM
Sana Biotechnology, Inc. (SANA) released Q4 earnings snapshot detailing quarterly financial results. Q4 earnings snapshots highlight financial performance and cash position, moderately influencing biotech investor sentiment and trajectory.

26 Feb

3 Insider Monkey, 2:27 PM
Sana Biotechnology appoints industry veteran Brian Piper as its new CFO to lead financial strategy amid ongoing biotech developments. CFO appointment bolsters financial expertise, potentially enhancing funding efforts and operational efficiency in a capital-intensive biotech sector.

17 Feb

3 GlobeNewswire, 9:00 AM
Sana Biotechnology appointed Brian Piper as Executive Vice President and Chief Financial Officer, bringing over 20 years of finance experience from roles at Denali Therapeutics, Bluebird Bio, and Alexion Pharmaceuticals. New CFO appointment affects financial strategy and investor sentiment in key operational areas.

30 Jan

3 Zacks, 12:00 PM
Sana Biotechnology, Inc. (SANA) has experienced a 5.46% increase in its stock price over the past week. This uptick reflects positive market sentiment and potential investor interest in the company's developments. Analysts are monitoring the company's progress in biotechnology and its impact on future performance. The stock price increase indicates moderate investor interest, but it is not expected to fundamentally alter the company's trajectory.

23 Jan

4 Zacks, 9:55 AM
Wall Street analysts project a potential surge of 74.2% for Sana Biotechnology, Inc. (SANA), driven by positive sentiment surrounding its innovative therapies and strategic developments. The company's focus on gene and cell therapies positions it favorably within the biotech sector, attracting investor interest. Analysts highlight the potential for significant growth, urging investors to consider the stock before making investment decisions. Analyst projections indicate significant growth potential driven by strategic developments in innovative therapies.

8 Jan

3 Simply Wall St.Simply Wall St.Simply Wall St.Simply Wall St.Simply Wall St.Simply Wall St.Simply Wall St.Simply Wall St., 2:13 PM
Sana Biotechnology, Inc. (SANA) has experienced notable share price momentum recently, prompting an assessment of its valuation. Analysts are evaluating the implications of this price movement on the company's future performance and market positioning. Factors such as recent developments in product innovation and market dynamics are being considered to understand how they may influence investor sentiment and the overall trajectory of the company. Recent share price momentum may moderately influence investor sentiment and financial performance.

7 Jan

3 GlobeNewswire, 4:26 PM
Sana Biotechnology, Inc. will present at the 44th Annual J.P. Morgan Healthcare Conference, showcasing its advancements in cell and gene therapies. The conference is a significant event for healthcare companies to discuss innovations and strategies with investors and industry leaders. Participation in a major healthcare conference can enhance visibility and investor interest, potentially impacting market sentiment.

6 Jan

4 Zacks, 7:06 AM
Sana Biotechnology, Inc. is highlighted among three genomics stocks worth tracking this year due to its innovative approaches in cell and gene therapy. The company focuses on developing engineered cells as potential treatments for various diseases, positioning itself strategically in the growing biotech sector. Investors are encouraged to monitor its advancements and market performance closely as the company navigates the competitive landscape. Sana's focus on innovative therapies and its strategic positioning in the biotech sector suggest significant potential for future growth and market impact.

28 Dec

4 Insider MonkeyInsider MonkeyInsider Monkey, 10:05 AM
Sana Biotechnology, Inc. has successfully demonstrated in vivo gene editing of stem cells, as detailed in a recent publication in Nature. This breakthrough showcases the company's advancements in gene therapy and regenerative medicine, potentially paving the way for innovative treatments for various diseases. The research highlights Sana's proprietary technology and its implications for future therapeutic applications. Successful in vivo gene editing represents a significant advancement in gene therapy that could enhance Sana's competitive position and market potential.

8 Dec

4 GlobeNewswire, 9:00 AM
Sana Biotechnology, Inc. announced the publication of research in Nature Biotechnology demonstrating successful in vivo gene editing of human hematopoietic stem cells using its Fusogen platform in preclinical models. This advancement highlights the potential of Sana's technology in gene therapy applications, particularly for blood disorders. The publication of significant research findings could lead to major advancements in gene therapy and enhance Sana's competitive positioning in the biotechnology sector.

1 Dec

4 Simply Wall St., 2:05 AM
Sana Biotechnology, Inc. is focusing on innovative therapies for diabetes and autoimmune diseases, aiming to leverage its proprietary platform to develop transformative treatments. The company is prioritizing its pipeline to address significant unmet medical needs in these areas, which could enhance its competitive positioning and market presence. Strategic partnerships and advancements in its research are expected to play a crucial role in shaping its future direction and investor interest. The focus on innovative therapies for diabetes and autoimmune diseases could significantly alter the company's trajectory and investor sentiment.

30 Nov

3 Simply Wall St., 10:07 AM
Sana Biotechnology, Inc. (SANA) has experienced strong year-to-date share price gains, prompting an assessment of its valuation. The company focuses on developing engineered cell therapies and has made significant progress in its clinical programs. Analysts are evaluating the sustainability of its stock performance and potential future growth, considering factors such as market conditions and competitive landscape. Investors are keenly observing Sana's strategic initiatives and product pipeline as they weigh the company's long-term prospects against its recent stock performance. Sana's advancements in engineered cell therapies and stock performance indicate a moderately noticeable influence on its future market positioning.

28 Nov

4 Insider Monkey, 10:11 AM
Sana Biotechnology, Inc. (SANA) experienced a 14.5% surge in its stock price ahead of anticipated business announcements. Investors are reacting positively to the upcoming news, which is expected to provide insights into the company's strategic direction and potential developments in its biotechnology initiatives. Upcoming business announcements are likely to significantly impact investor sentiment and the company's strategic direction.

18 Nov

4 Zacks, 8:48 AM
Sana Biotechnology, Inc. (SANA) is highlighted as one of the top genomics stocks to consider for investment. The company focuses on developing cell and gene therapies, aiming to address various diseases. With advancements in technology and a strong pipeline, Sana is positioned to capitalize on the growing demand for innovative treatments in the biotech sector. Investors are encouraged to evaluate its potential alongside other leading genomics firms. Sana's focus on cell and gene therapies positions it for significant impact in the evolving biotech landscape.

4 Insider Monkey, 6:17 AM
Sana Biotechnology, Inc. has garnered analyst support due to its strategic focus and strong cash position. The company is concentrating on advancing its cell and gene therapy platforms, which are expected to drive future growth. Analysts highlight Sana's robust financial resources as a key advantage, enabling it to pursue innovative projects and navigate market challenges effectively. This strategic alignment and financial strength are seen as pivotal for the company's long-term success. Strategic focus and strong cash position are likely to significantly impact future performance and investor sentiment.

16 Nov

4 , 7:13 PM
Sana Biotechnology, Inc. is restructuring its cost structure to enhance its long-term competitive position. The company aims to streamline operations and focus on key areas that could lead to improved financial performance and innovation. This strategic shift is expected to better position Sana in the biotechnology market, potentially attracting investor interest and improving market sentiment. The restructuring of the cost structure is a significant strategic move that could enhance competitive positioning and investor sentiment.

12 Nov

4 Zacks, 12:00 PM
Sana Biotechnology, Inc. (SANA) has received a rating upgrade to 'Buy' from analysts, reflecting positive sentiment about the company's future prospects. This upgrade is attributed to recent advancements in their gene therapy and cell therapy programs, which are expected to enhance their market position. Investors are encouraged by the potential for significant growth as Sana continues to innovate in the biotechnology sector. The rating upgrade indicates significant positive sentiment and potential growth due to advancements in key therapeutic areas.

9 Nov

4 Simply Wall St., 2:06 AM
Sana Biotechnology, Inc. has undergone a strategic refocus, emphasizing its commitment to developing innovative cell and gene therapies. Recent clinical updates have shown promising results, particularly in its programs targeting various diseases. The company aims to leverage its advancements to enhance its market position and attract investor interest, signaling a potential shift in its operational trajectory. Significant clinical updates and a strategic refocus are likely to alter the company's trajectory and investor sentiment.

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