Ionis Pharmaceuticals, Inc. (IONS) vs Ligand Pharmaceuticals Incorporated (LGND)

• Ionis Pharmaceuticals, Inc. IONS 39.48 ▲ +1.75%
• Ligand Pharmaceuticals Incorporated LGND 306.43 ▲ +2.48%

Ionis Pharmaceuticals, Inc. and Ligand Pharmaceuticals Incorporated are both Biotechnology companies. Ionis Pharmaceuticals, Inc. and Ligand Pharmaceuticals Incorporated are of similar size ($6.5B and $6.0B). Ionis Pharmaceuticals, Inc. has negative trailing earnings, so its P/E is not meaningful; Ligand Pharmaceuticals Incorporated trades at 116×. Ligand Pharmaceuticals Incorporated grew revenue faster over the last twelve months: 1.03% against −7.41%. Ligand Pharmaceuticals Incorporated has the higher net margin (20.3% vs −64.7%) and the higher return on invested capital (1.27% vs 0.00%). Across the 18 metrics below, Ligand Pharmaceuticals Incorporated leads on 14 and Ionis Pharmaceuticals, Inc. on 4.