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Ionis Pharmaceuticals, Inc. (IONS) vs Kodiak Sciences Inc. (KOD)

Ionis Pharmaceuticals, Inc. and Kodiak Sciences Inc. are both Biotechnology companies. Ionis Pharmaceuticals, Inc. is the larger, with a market value of $6.5B against $5.7B — 1.1× the size. Kodiak Sciences Inc. has the higher net margin (0.00% vs −64.7%) and the higher return on invested capital (0.00% vs 0.00%). Across the 13 metrics below, Kodiak Sciences Inc. leads on 7 and Ionis Pharmaceuticals, Inc. on 6.

Valuation

Metric IONS KOD Biotechnology median
P/E n/m n/m 10.26
P/S 7.36 n/m 9.18
P/B 14.62 94.00 2.05
Price to free cash flow n/m n/m 24.81
EV/EBITDA n/m n/m 0.65
EV/Sales 7.05 n/m 8.98
Earnings yield (8.90%) (4.57%) (34.89%)
Free cash flow yield (8.83%) (2.78%) (24.52%)

Profitability

Metric IONS KOD Biotechnology median
Gross margin 98.17% 0.00% 65.16%
Operating margin (68.00%) 0.00% 0.00%
Net margin (64.66%) 0.00% 0.00%
Free cash flow margin (64.93%) 0.00% 0.00%
Return on equity (105.50%) (368.37%) (50.12%)
Return on assets (18.90%) (94.25%) (45.60%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric IONS KOD Biotechnology median
Revenue growth (TTM) (7.41%) — 6.26%
EPS growth (last fiscal year) 21.71% (28.96%) 29.88%
Revenue growth, 5-year CAGR 5.29% — 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric IONS KOD Biotechnology median
Debt to equity 3.07 0.00 0.00
Current ratio 7.89 2.49 4.89
Net debt to EBITDA 2.39 1.01 1.01

Dividend

Metric IONS KOD Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric IONS KOD Biotechnology median
Market cap 6.45b 5.72b 172.11m

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