Arrowhead Pharmaceuticals, Inc. (ARWR) vs Madrigal Pharmaceuticals, Inc. (MDGL)

Arrowhead Pharmaceuticals, Inc. and Madrigal Pharmaceuticals, Inc. are both Biotechnology companies. Madrigal Pharmaceuticals, Inc. is the larger, with a market value of $9.3B against $8.1B — 1.1× the size. Madrigal Pharmaceuticals, Inc. grew revenue faster over the last twelve months: 92.8% against 16.1%. Madrigal Pharmaceuticals, Inc. has the higher net margin (−10.9% vs −47.8%) and the lower return on invested capital (−1,480.3% vs 0.00%). Across the 17 metrics below, Madrigal Pharmaceuticals, Inc. leads on 9 and Arrowhead Pharmaceuticals, Inc. on 8.

Valuation

Metric ARWR MDGL Biotechnology median
P/E n/m n/m 10.26
P/S 12.34 8.19 9.18
P/B 17.73 18.66 2.05
Price to free cash flow n/m n/m 24.81
EV/EBITDA n/m n/m 0.65
EV/Sales 11.24 7.76 8.98
Earnings yield (3.90%) (1.48%) (34.89%)
Free cash flow yield (0.91%) (1.47%) (24.52%)

Profitability

Metric ARWR MDGL Biotechnology median
Gross margin 100.00% 90.96% 65.16%
Operating margin (33.82%) (10.69%) 0.00%
Net margin (47.79%) (10.89%) 0.00%
Free cash flow margin (11.22%) (11.81%) 0.00%
Return on equity (64.91%) (24.82%) (50.12%)
Return on assets (18.32%) (11.12%) (45.60%)
Return on invested capital 0.00% (1,480.32%) 0.00%

Growth

Metric ARWR MDGL Biotechnology median
Revenue growth (TTM) 16.13% 92.80% 6.26%
EPS growth (last fiscal year) 99.80% 41.32% 29.88%
Revenue growth, 5-year CAGR 56.63% — 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric ARWR MDGL Biotechnology median
Debt to equity 1.85 0.54 0.00
Current ratio 5.90 3.05 4.89
Net debt to EBITDA (5.70) 2.21 1.01

Dividend

Metric ARWR MDGL Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric ARWR MDGL Biotechnology median
Market cap 8.12b 9.29b 172.11m

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