Tyra Biosciences, Inc.

TYRA Healthcare Biotechnology

In the quarter to June 2026, EPS fell 46.8% and free cash flow fell 31.3%, each against the same quarter a year earlier. Insiders bought in the last twelve months.

18.52 0.52 −2.73%
Market cap
$1.3B
P/E
0.0×
Fwd P/E
—
Dividend yield
—
F-score
n/a
Altman Z
n/a
Beneish M
n/a
Dividend safety
n/a

Insider Decisions trades per month

Total buys 0.02
Total sells 10.59
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — — — — 1 —
Sell 3 2 1 1 1 — — — — — — —
Insider Ownership 30.64%

Capital & Financial Ratios $m

Market Cap 1,310.00
Revenue —
Net Income (148.56)
Free Cash Flow (109.90)
Net Debt (353.94)
Current Ratio 14.91 (at or above 1.5: strong)
Debt/Equity 0.00 (at or below 0.5: strong)
P/E ratio 0.00
Fwd P/E —
P/S ratio 0.00
P/B ratio 3.46
Past 5Y EPS Growth —
This Y EPS Growth (31.94%) (below 0%: weak)
Next Y EPS Growth (5.58%) (below 0%: weak)
Next Y revenue growth —
Next 5Y EPS Growth (16.83%) (below 0%: weak)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/B against its own 10 years 77.03%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
predictions special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 203 341 256 354
Receivables — — — —
Inventory — — — —
Other — — — —
212 347 265 367
2023 2024 2025 Q'26
Payables 5 1 1 2
ST’ Debt — — — —
Other — — — —
15 15 18 25

Compound Annual Growth %

10y 5y 3y
Sales — — —
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 0.00% 0.17%

Revenue $m

Year
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (33) (31) — — —
’25 (25) (24) (22) (24) (95)
’24 (22) (10) (18) (20) (70)
’23 (10) (10) (17) (14) (50)
’22 (9) (17) (12) (12) (50)
’21 (5) (4) (6) (9) (24)
’20 (1) (2) (5) (3) (8)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (33) (31) — — —
’25 (25) (24) (22) (24) (95)
’24 (22) (11) (18) (20) (70)
’23 (10) (10) (17) (14) (51)
’22 (9) (17) (12) (12) (51)
’21 (5) (5) (6) (9) (24)
’20 (1) (2) (5) (3) (8)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.64) (0.69) — — —
’25 (0.47) (0.47) (0.50) (0.57) (2.01)
’24 (0.35) (0.32) (0.41) (0.43) (1.51)
’23 (0.28) (0.31) (0.49) (0.53) (1.62)
’22 (0.36) (0.36) (0.30) (0.31) (1.32)
’21 (2.10) (2.43) (0.72) (0.24) (1.91)
’20 (0.03) (0.04) (1.47) — (6.05)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.2
1Buy 2 3Hold 4 5Sell

Ten years at a glance

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low — — — — — 11.37 4.93 6.55 11.24 6.42

Analyst estimates 2026–2028

Powerpack
High — — — — — 31.36 14.27 19.74 29.60 26.41
People
People Employees — — — — 16 25 38 49 60 87
Revenue/emp, $m — — — — 0.00 0.00 0.00 0.00 0.00 0.00
Income, $m
Income, $m Revenue — — — — — — — — — —
Gross margin, % — — — 0.00 0.00 0.00 0.00 — — —
EBT — — — (4) (9) (26) (55) (69) (86) (120)
EBT margin, % — — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Net income — 0 — (4) (9) (26) (55) (69) (86) (120)
Depreciation — — — 0 0 0 0 0 1 1
Per share, $
Per share, $ Revenue — — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Earnings — — — (0.10) (6.05) (1.91) (1.32) (1.62) (1.51) (2.01)
Cash flow — — — (0.06) (5.03) (1.72) (1.20) (1.17) (1.22) (1.60)
Capex — — — 0.00 (0.20) (0.05) (0.01) (0.02) (0.01) 0.00
Free cash flow — — — (0.06) (5.24) (1.77) (1.21) (1.19) (1.23) (1.60)
Book value — — — (0.11) (8.84) 21.90 6.16 4.78 6.00 4.35
Shares, m — — — 43 2 14 42 43 57 60
Valuation, ×
Valuation, × P/E — — — — — — — — — —
P/S — — — — — — — — — —
P/B — — — — — — — — — —
EV/Sales — — — — — — — — — —
EV/FCF — — — — — — — — — —
Cash, $m
Cash, $m Operating cash flow — — — (3) (8) (24) (50) (50) (70) (95)
Capex — — — 0 0 (1) (1) (1) (1) 0
Free cash flow — — — (3) (8) (24) (51) (51) (70) (95)
Balance, $m
Balance, $m Working capital — — — (5) 13 300 252 196 333 247
Total debt — — — 0 28 1 3 — — —
Net debt — — — 0 (15) (302) (251) (203) (341) (256)
Shareholders’ equity — — — (5) (14) 302 258 204 343 259
Returns, %
Returns, % ROA — — — (1,539.77) (112.90) (16.30) (19.31) (28.10) (29.34) (37.13)
ROIC — — — 0.00 0.00 0.00 (556.67) (6,300.84) (3,807.64) (2,614.25)
ROE — — — 44.24 101.59 (18.25) (19.77) (29.92) (31.60) (39.83)
Negative figures in brackets.

All 10 years →

Charts ten years each

Tyra Biosciences, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
AAPG Ascentage Pharma Group International - Unsponsored ADR $1.4B — — — — +17.74% (above 0%: growing) — — Compare
OMER Omeros Corporation $1.4B 9.5× 2.1× +35.46% (above 0%: growing) n/m +118.70% (above 0%: growing) 97.20% 0.26% Compare
INBX Inhibrx Biosciences, Inc. $1.3B — (loss-making) — (loss-making) +992.44% (above 0%: growing) n/m +0.12% (above 0%: growing) 100.00% 0.00% Compare
ORIC Oric Pharmaceuticals, Inc. $1.3B — (loss-making) — — n/m −3.42% (below 0%: shrinking) 0.00% 0.00% Compare
TYRA Tyra Biosciences, Inc. $1.3B — (loss-making) — — n/m −31.34% (below 0%: shrinking) 0.00% 0.00%
GHRS GH Research PLC $1.3B — (loss-making) — — n/m −66.62% (below 0%: shrinking) 0.00% 0.00% Compare
NKTR Nektar Therapeutics $1.3B — (loss-making) — (loss-making) −9.34% (below 0%: shrinking) n/m −65.73% (below 0%: shrinking) 100.00% (417.94%) Compare
DRTS Alpha Tau Medical Ltd. $1.2B — (loss-making) — — n/m −30.42% (below 0%: shrinking) 0.00% 0.00% Compare
SNDX Syndax Pharmaceuticals, Inc. $1.2B — (loss-making) — (loss-making) +91.76% (above 0%: growing) n/m +65.47% (above 0%: growing) 95.59% (54.95%) Compare
Median of peers $1.3B — — +63.61% — −1.65% 95.59% 0.00%

All 614 Biotechnology stocks →

Tyra Biosciences, Inc. (TYRA) key facts

  • Concern: Tyra Biosciences, Inc. reported a net loss of $119.9 million, or a loss of $2.01 per share, for fiscal 2025.
  • Tyra Biosciences, Inc. (TYRA) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, TYRA traded at $18.52, a market capitalization of $1.3 billion.
  • Return on equity was −39.8% and debt-to-equity 0.00.

Source: company filings (standardised) and stockrow calculations.

Tyra Biosciences, Inc. (TYRA) Latest News

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