Tyra Biosciences, Inc.

TYRA Healthcare Biotechnology

EPS
−46.8%
Free cash flow
−31.3%

Quarter to June 2026, against a year earlier

21.09 0.20 +0.96%
Market cap
$1.4B
P/E
0.0×
Fwd P/E
—
Dividend yield
—
F-score
n/a
Altman Z
n/a
Beneish M
n/a
Dividend safety
n/a

Insider Decisions last twelve months

Bought, $m 0.02
Sold, $m 1.45
Trades a month
Jan 26 Apr 26 Jul 26 Oct 26
Buy — — — — — — — — — 1 — —
Sell 2 1 1 1 — — — — — — — —
Insider Ownership 30.64%

Capital & Financial Ratios $m

Size
Market Cap 1,440.00
Revenue ttm —
Net income ttm (148.56)
Free cash flow ttm (109.90)
Net debt Q (353.94)
Valuation
P/E 0.00
Forward P/E —
Price / sales 0.00
Forward P/S Powerpack
Price / FCF 0.00
Price / book 3.94
Financial health
Current ratio Q 14.91 (at or above 1.5: strong)
Debt / equity Q 0.00 (at or below 0.5: strong)
Interest coverage Q 0.00
Growth
Revenue growth Q —
Operating income growth Q −55.80% (below 0%: shrinking)
EPS, this year −31.94% (below 0%: weak)
EPS, next year A −5.58% (below 0%: weak)
Revenue, next year A —
EPS, past 5 yrs —
EPS, next 5 yrs A −16.83% (below 0%: weak)

Green and red mark values outside typical ranges; (Q) is the latest quarter, (A) analysts’ estimates. How we judge →

Valuation vs history

P/B against its own 10 years 80.50%
10-year low 10-year high

Dividends

Yield
—
Annual rate
—
Payout ratio
—

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 203 341 256 354
Receivables — — — —
Inventory — — — —
Other — — — —
212 347 265 367
2023 2024 2025 Q'26
Payables 5 1 1 2
ST’ Debt — — — —
Other — — — —
15 15 18 25

Compound Annual Growth %

10y 5y 3y
Sales — — —
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 0.00% 0.17%

Earnings Trends EPS, adjusted, against the consensus

EPS $

Mar Jun Sep Dec Year
’26 (0.64) (0.69) — — —
’25 (0.47) (0.47) (0.50) (0.57) (2.01)
’24 (0.35) (0.32) (0.41) (0.43) (1.51)
’23 (0.28) (0.31) (0.49) (0.53) (1.62)
’22 (0.36) (0.36) (0.30) (0.31) (1.32)
’21 (2.10) (2.43) (0.72) (0.24) (1.91)
’20 (0.03) (0.04) (1.47) — (6.05)
Fiscal quarters ending in the months shown.

Revenue $m

Year
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (33) (31) — — —
’25 (25) (24) (22) (24) (95)
’24 (22) (10) (18) (20) (70)
’23 (10) (10) (17) (14) (50)
’22 (9) (17) (12) (12) (50)
’21 (5) (4) (6) (9) (24)
’20 (1) (2) (5) (3) (8)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (33) (31) — — —
’25 (25) (24) (22) (24) (95)
’24 (22) (11) (18) (20) (70)
’23 (10) (10) (17) (14) (51)
’22 (9) (17) (12) (12) (51)
’21 (5) (5) (6) (9) (24)
’20 (1) (2) (5) (3) (8)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.2
1Buy 2 3Hold 4 5Sell

Ten years at a glance

Ten-year view Analyst estimates Powerpack
Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 TTM Jun ’26 Trend 10 yrs 2026e 2027e 2028e Next 3/yr
Income, $m
Income, $m Revenue — — — — — — — — — — — — 1 1 1 0.0%
Gross margin, % — — — 0.00 0.00 0.00 0.00 — — — 0.00 0.0 pt
EBT — — — (4) (9) (26) (55) (69) (86) (120) (149) +75.8%
EBT margin, % — — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.0 pt
Net income — 0 — (4) (9) (26) (55) (69) (86) (120) (149) n/m
Per share, $
Per share, $ Revenue — — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 n/m
Earnings — — — (0.10) (6.05) (1.91) (1.32) (1.62) (1.51) (2.01) (2.40) +64.9%
Cash flow — — — (0.06) (5.03) (1.72) (1.20) (1.17) (1.22) (1.60) (1.66) +72.1%
Capex — — — 0.00 (0.20) (0.05) (0.01) (0.02) (0.01) 0.00 0.00 n/m
Free cash flow — — — (0.06) (5.24) (1.77) (1.21) (1.19) (1.23) (1.60) (1.67) +72.1%
Book value — — — (0.11) (8.84) 21.90 6.16 4.78 6.00 4.35 5.36 n/m
Shares, m — — — 43 2 14 42 43 57 60 62 +5.8%
Valuation, ×
Valuation, × P/E — — — — — — — — — — 0 —
P/S — — — — — — — — — — 0 —
P/B — — — — — — — — — — 0 —
EV/Sales — — — — — — — — — — 0 —
EV/FCF — — — — — — — — — — 0 —
Cash, $m
Cash, $m Operating cash flow — — — (3) (8) (24) (50) (50) (70) (95) (110) +82.0%
Capex — — — 0 0 (1) (1) (1) (1) 0 0 +38.5%
Free cash flow — — — (3) (8) (24) (51) (51) (70) (95) (110) +82.0%
Balance, $m
Balance, $m Working capital — — — (5) 13 300 252 196 333 247 342 n/m
Net debt — — — 0 (15) (302) (251) (203) (341) (256) (354) n/m
Shareholders’ equity — — — (5) (14) 302 258 204 343 259 354 n/m
Returns, %
Returns, % ROA — — — (1,539.77) (112.90) (16.30) (19.31) (28.10) (29.34) (37.13) (42.15) +1,502.6 pt
ROIC — — — 0.00 0.00 0.00 (556.67) (6,300.84) (3,807.64) (2,614.25) 0.00 (2,614.2) pt
ROE — — — 44.24 101.59 (18.25) (19.77) (29.92) (31.60) (39.83) (45.31) (84.1) pt
People
People Employees — — — — 16 25 38 49 60 87 — +40.3%
Revenue/emp, $m — — — — 0.00 0.00 0.00 0.00 0.00 0.00 — n/m
Negative figures in brackets.
estimates

All 10 years →

Tyra Biosciences, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
PGEN Precigen, Inc. $1.5B 60.3× 32.2× +2,437.58% (above 0%: growing) n/m +140.34% (above 0%: growing) 91.22% 52.13% Compare
NUVB Nuvation Bio Inc. $1.5B — (loss-making) — (loss-making) +242.61% (above 0%: growing) n/m +34.07% (above 0%: growing) 73.46% (93.90%) Compare
ADRX ADARx Pharmaceuticals, Inc. $1.5B — — — — — — — Compare
IMCR Immunocore Holdings PLC Sponsored ADR $1.5B — (loss-making) — (loss-making) −1.42% (below 0%: shrinking) n/m +440.97% (above 0%: growing) 99.34% (13.31%) Compare
QURE uniQure N.V. $1.5B — (loss-making) — (loss-making) +40.39% (above 0%: growing) n/m +27.66% (above 0%: growing) 95.46% (1,019.63%) Compare
TYRA Tyra Biosciences, Inc. $1.4B — (loss-making) — — n/m −31.34% (below 0%: shrinking) 0.00% 0.00%
AAPG Ascentage Pharma Group International - Unsponsored ADR $1.4B — — — — +17.74% (above 0%: growing) — — Compare
OCUL Ocular Therapeutix, Inc. $1.4B — (loss-making) — (loss-making) +0.12% (above 0%: growing) n/m −25.35% (below 0%: shrinking) 85.08% (609.34%) Compare
KRSA Korsana Biosciences, Inc. $1.4B — (loss-making) — (loss-making) −43.24% (below 0%: shrinking) n/m −184.69% (below 0%: shrinking) 100.00% 0.00% Compare
Median of peers $1.5B — — +20.25% — +27.66% 93.34% (53.60%)

All 621 Biotechnology stocks →

Pay and ownership Proxy statement filed 17 April 2026

Ownership

Directors and executive officers, together 12.50%
Entities affiliated with RA Capital Healthcare Fund, L.P. 20.60%
Entities affiliated with FMR LLC 13.00%
Nextech VI Oncology SCSp 6.80%
Robert More 6.50%
Alta Partners NextGen Fund II, L.P. 6.40%
Entities affiliated with Commodore Capital LP 5.70%
Entities affiliated with Canaan XI L.P. 5.70%
Entities affiliated with Farallon Capital Partners, L.P. 5.00%
Ownership is the proxy’s own table: the directors and officers as a group, and every holder of 5% or more. Read the proxy statement

Tyra Biosciences, Inc. (TYRA) Latest News

17 Oct

22 Aug

Impact 4 · · clinicaltrialsarena.com
stockrow.com/TYRA · For information only; not investment advice. · © 2026 stockrow.com