Saturday 17 October 2026
Export STOK’s income statement to Excel — free account
Stoke Therapeutics, Inc.
STOK Healthcare Biotechnology
Stoke Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $184.4 million, up 404.5% from fiscal 2024. In the quarter to June 2026, revenue fell 32.5%, EPS fell 132.5% and free cash flow fell 129.0%, each against the same quarter a year earlier.
24.17
0.44
−1.79%
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Target Price Range
Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Trend | 2026e | 2027e | 2028e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Price, $ | |||||||||||||||
| Price, $ | Low | — | — | — | 19.21 | 15.82 | 17.76 | 6.88 | 3.35 | 4.09 | 5.35 |
Analyst estimates 2026–2028 Powerpack |
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| High | — | — | — | 39.04 | 64.54 | 71.58 | 26.60 | 14.00 | 17.58 | 38.69 | |||||
| People | |||||||||||||||
| People | Employees | — | — | 44 | 56 | 79 | 102 | 117 | 110 | 128 | 170 | ||||
| Revenue/emp, $m | — | — | 0.00 | 0.00 | 0.00 | 0.00 | 0.11 | 0.08 | 0.29 | 1.08 | |||||
| Income, $m | |||||||||||||||
| Income, $m | Revenue | — | — | — | — | — | — | 12 | 9 | 37 | 184 | ||||
| Gross margin, % | — | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 100.00 | 100.00 | 100.00 | 100.00 | |||||
| EBT | — | (6) | (13) | (32) | (52) | (86) | (101) | (105) | (89) | (7) | |||||
| EBT margin, % | — | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | (814.73) | (1,192.47) | (243.42) | (3.73) | |||||
| Net income | — | 0 | (13) | (32) | (52) | (86) | (101) | (105) | (89) | (7) | |||||
| Depreciation | — | 0 | 0 | 0 | 1 | 1 | 1 | 2 | 1 | 1 | |||||
| Per share, $ | |||||||||||||||
| Per share, $ | Revenue | — | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.32 | 0.20 | 0.68 | 3.11 | ||||
| Earnings | — | (0.17) | (17.65) | (1.80) | (1.56) | (2.34) | (2.60) | (2.38) | (1.65) | (0.12) | |||||
| Cash flow | — | (0.16) | (15.46) | (1.73) | (1.26) | (1.82) | (0.82) | (1.84) | (1.61) | 0.77 | |||||
| Capex | — | 0.00 | (1.30) | (0.09) | (0.03) | (0.03) | (0.10) | (0.04) | 0.00 | (0.01) | |||||
| Free cash flow | — | (0.16) | (16.76) | (1.82) | (1.29) | (1.85) | (0.92) | (1.88) | (1.61) | 0.76 | |||||
| Book value | — | (0.04) | 148.13 | 12.49 | 8.54 | 5.93 | 4.75 | 3.63 | 4.24 | 5.95 | |||||
| Shares, m | — | 33 | 1 | 18 | 33 | 37 | 39 | 44 | 54 | 59 | |||||
| Valuation, × | |||||||||||||||
| Valuation, × | P/E | — | — | — | — | — | — | 0.00 | 0.00 | 0.00 | 0.00 | ||||
| P/S | — | — | — | — | — | — | 28.50 | 29.36 | 16.30 | 10.19 | |||||
| P/B | — | — | — | — | — | — | 1.91 | 1.62 | 2.60 | 5.33 | |||||
| EV/Sales | — | — | — | — | — | — | 9.99 | 6.43 | 10.36 | 8.65 | |||||
| EV/FCF | — | — | — | — | — | — | (3.46) | (0.68) | (4.35) | 35.51 | |||||
| Cash, $m | |||||||||||||||
| Cash, $m | Operating cash flow | — | (5) | (11) | (31) | (42) | (67) | (32) | (81) | (87) | 46 | ||||
| Capex | — | 0 | (1) | (2) | (1) | (1) | (4) | (2) | 0 | (1) | |||||
| Free cash flow | — | (5) | (12) | (33) | (43) | (68) | (36) | (83) | (87) | 45 | |||||
| Balance, $m | |||||||||||||||
| Balance, $m | Working capital | — | (2) | 104 | 222 | 283 | 212 | 213 | 185 | 193 | 248 | ||||
| Total debt | — | 3 | — | — | 0 | 5 | 5 | — | — | — | |||||
| Net debt | — | 1 | (105) | (222) | (287) | (220) | (230) | (201) | (217) | (285) | |||||
| Shareholders’ equity | — | (1) | 105 | 224 | 286 | 218 | 185 | 160 | 229 | 352 | |||||
| Returns, % | |||||||||||||||
| Returns, % | ROA | — | (10.11) | (23.29) | (19.22) | (19.84) | (31.97) | (40.84) | (43.23) | (35.60) | (2.00) | ||||
| ROIC | — | 0.00 | 0.00 | (1,139.44) | 0.00 | 0.00 | 0.00 | 0.00 | (525.92) | (19.12) | |||||
| ROE | — | (10.71) | (24.13) | (19.62) | (20.47) | (34.06) | (50.20) | (60.80) | (45.80) | (2.37) | |||||
Negative figures in brackets.
Fiscal years to Dec 2025 · latest quarter Jun 2026
Charts ten years each
Stoke Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| ZBIO Zenas BioPharma, Inc. | $1.7B | — (loss-making) | — (loss-making) | — | n/m | −37.12% (below 0%: shrinking) | 100.00% | (10,765.90%) | Compare |
| OCUL Ocular Therapeutix, Inc. | $1.6B | — (loss-making) | — (loss-making) | +0.12% (above 0%: growing) | n/m | −25.35% (below 0%: shrinking) | 85.08% | (609.34%) | Compare |
| STOK Stoke Therapeutics, Inc. | $1.6B | — (loss-making) | — (loss-making) | −32.51% (below 0%: shrinking) | n/m | −128.97% (below 0%: shrinking) | 100.00% | (701.65%) | |
| NTLA Intellia Therapeutics, Inc. | $1.6B | — (loss-making) | — (loss-making) | −46.23% (below 0%: shrinking) | n/m | +15.05% (above 0%: growing) | 100.00% | (1,472.25%) | Compare |
| GPCR Structure Therapeutics Inc. Sponsored ADR | $1.6B | — (loss-making) | — | — | n/m | −119.15% (below 0%: shrinking) | 0.00% | 0.00% | Compare |
| QURE uniQure N.V. | $1.6B | — (loss-making) | — (loss-making) | +11.00% (above 0%: growing) | n/m | +27.66% (above 0%: growing) | 94.01% | (893.73%) | Compare |
| KRSA Korsana Biosciences, Inc. | $1.5B | — (loss-making) | — (loss-making) | −43.24% (below 0%: shrinking) | n/m | −184.69% (below 0%: shrinking) | 100.00% | 0.00% | Compare |
| MAZE Maze Therapeutics, Inc. | $1.5B | — (loss-making) | — | — | n/m | +50.21% (above 0%: growing) | 100.00% | 0.00% | Compare |
| ABSI Absci Corporation | $1.5B | — (loss-making) | — (loss-making) | −46.37% (below 0%: shrinking) | n/m | −71.74% (below 0%: shrinking) | 100.00% | (10,741.51%) | Compare |
| Median of peers | $1.6B | — | — | −43.24% | — | −31.23% | 100.00% | (751.53%) |
Stoke Therapeutics, Inc. (STOK) key facts
- Concern: Stoke Therapeutics, Inc. reported a net loss of $6.9 million, or a loss of $0.12 per share, for fiscal 2025.
- Strength: Stoke Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $184.4 million, up 404.5% from fiscal 2024.
- Stoke Therapeutics, Inc. (STOK) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
- As of October 16, 2026, STOK traded at $24.17, a market capitalization of $1.6 billion.
- Trailing earnings are negative, so a P/E ratio is not meaningful; the stock trades at 57.8× sales.
- Return on equity was −2.37% and debt-to-equity 0.00.
- Its Piotroski F-score is 5 out of 9 and its Altman Z-score is 16.42 (safe zone) for fiscal 2025.