Lakefront Biotherapeutics - Sponsored ADR LKFT

29.38 (0.98) (3.23%) as of 25 Sep
Market cap
$2.0B
P/E
0.0×
Growth Flags show if company had growth for consecutive years

Insider Decisions

in millions of $
Nov 25 Feb 26 May 26 Aug 26
Buy — — — — — — — — — — — —
Sell — — — — — — — — — — — —
Insider Ownership 25.60%

Capital & Financial Ratios

Market Cap 1,990.00
Revenue 282.04
Net Income (652.45)
Free Cash Flow (524.53)
Net Debt (2,598.37)
Current Ratio 32.84
Debt/Equity 0.00
P/E ratio 0.00
P/S ratio 6.86
P/B ratio 0.51
Past 5Y EPS Growth (16.02%)
This Y EPS Growth (144.34%)
Next Y EPS Growth 4.98%
Next 5Y EPS Growth 47.44%
in millions of $

Dividends

Payout Ratio 0.00
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
predictions in italic, special payouts not included in total or ratios

Assets vs Liabilities

2023 2024 2025 Q'26
Cash 3,988 3,418 3,392 2,604
Receivables 71 95 59 65
Inventory 80 55 25 10
Other 40 46 8 6
4,179 3,614 3,484 2,685
2023 2024 2025 Q'26
Payables 146 107 118 77
ST’ Debt — — — —
Other 35 — 51 2
463 363 173 82
in millions of $

Compound Annual Growth

10y 5y 3y
Sales 34.03% 15.75% 33.21%
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value 24.62% 3.72% 11.22%

Revenue

Mar Jun Sep Dec Year
’26 8 — — — —
’25 79 — — — 1,258
’24 68 — — — 298
’23 194 163 128 — 259
’22 153 146 137 96 532
’21 150 184 76 164 574
’20 118 130 168 190 606
in millions of $ · fiscal quarters ending in the months shown

Operating Cash Flow

Mar Jun Sep Dec Year
’26 (97) (39) — — —
’25 (41) (127) (245) — (291)
’24 (133) (70) (287) — (346)
’23 (101) (133) (369) — (439)
’22 (70) (147) (106) (204) (527)
’21 (146) (99) (156) (195) (596)
’20 (76) (155) (225) (32) (488)
in millions of $ · fiscal quarters ending in the months shown

Free Cash Flow

Mar Jun Sep Dec Year
’26 (95) (38) — — —
’25 (46) (132) (260) — (306)
’24 (140) (141) (371) — (435)
’23 (105) (139) (379) — (458)
’22 (80) (155) (116) (214) (566)
’21 (157) (112) (174) (222) (665)
’20 (90) (168) (251) (83) (592)
in millions of $ · fiscal quarters ending in the months shown

EPS

Mar Jun Sep Dec Year
’26 0.26 — — — —
’25 (2.45) — — — 5.51
’24 1.49 — — — 1.21
’23 0.38 0.09 0.41 — 3.47
’22 (0.22) (0.31) 0.33 (3.23) (3.50)
’21 0.17 (1.18) (1.17) 0.31 (1.87)
’20 (0.86) (1.95) (1.46) (1.09) (5.46)
fiscal quarters ending in the months shown

Target Price Range

Analyst price targets

Recommendation Rating

2.4
1Buy 2 3Hold 4 5Sell
2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028
37.03 63.69 85.00 89.45 93.01 46.41 37.24 31.86 24.16 22.36

Analyst estimates 2026–2028

Powerpack
Low Price
73.37 104.12 122.28 217.29 274.03 113.71 72.11 48.07 42.46 37.78
High Price
508 600 725 1,003 1,304 1,309 1,338 1,123 704 452
Employees
0 0 1 1 0 0 0 0 0 3
Revenue/Emp
168 176 375 1,003 606 574 532 259 298 1,258
Revenue
100.00% 100.00% 100.00% 100.00% 100.00% 99.66% 97.61% 100.00% 87.35% 97.33%
Gross Margin
60 (131) (34) 168 (354) (146) (227) 6 (3) 340
EBT
35.78% (74.08%) (9.19%) 16.75% (58.42%) (25.37%) (42.58%) 2.35% (1.12%) 27.05%
EBT Margin
60 (131) (35) 168 (349) (122) (230) 229 80 363
Net Income
5 5 6 14 21 41 69 47 49 63
Depreciation
3.67 3.56 7.20 17.42 9.31 8.76 8.10 3.94 4.53 19.10
Revenue/Sh
1.29 (2.64) (0.66) 2.91 (5.36) (1.87) (3.50) 3.47 1.21 5.51
Earnings/Sh
5.80 (3.36) (3.23) 62.37 (7.50) (9.10) (8.03) (6.67) (5.26) (4.42)
Cash Flow/Sh
(0.12) (0.17) (0.31) (0.89) (1.60) (1.05) (0.58) (0.28) (1.35) (0.23)
Capex/Sh
5.68 (3.53) (3.54) 61.49 (9.10) (10.15) (8.61) (6.95) (6.60) (4.65)
Free CF/Sh
18.37 23.12 27.52 55.90 46.87 47.75 40.51 45.92 47.57 55.56
Book Value/Sh
46 49 52 58 65 66 66 66 66 66
Shares
0.00 0.00 0.00 80.17 0.00 0.00 0.00 0.00 11.59 0.00
PE Ratio
47.10 50.39 12.74 11.88 10.63 6.30 5.47 4.69 3.28 4.92
PS Ratio
3.59 3.59 3.33 3.70 2.11 1.15 1.09 0.95 0.58 0.75
PB Ratio
29.35 33.88 8.68 5.45 0.95 (3.37) (2.60) (2.44) (3.44) (3.21)
EV/Sales
12.64 25.27 (17.65) 1.54 (0.97) 2.91 2.45 1.69 1.84 1.74
EV/FCF
265 (166) (168) 3,594 (488) (596) (527) (439) (346) (291)
Op' Cash Flow
(5) (8) (16) (51) (104) (68) (38) (18) (89) (15)
Capex
260 (175) (184) 3,542 (592) (665) (566) (458) (435) (306)
FCF
1,000 1,160 1,310 5,929 5,408 5,082 3,913 3,716 3,251 3,311
Working Cap'
0 0 — 22 28 23 15 5 — 6
Total Debt
(1,084) (1,301) (1,524) (6,452) (5,868) (5,542) (4,298) (3,982) (3,418) (3,386)
Net Debt
840 1,144 1,434 3,221 3,050 3,127 2,661 3,026 3,135 3,661
Sh' Equity
7.07% (9.86%) (2.19%) 3.95% (5.24%) (1.93%) (4.13%) 4.72% 1.74% 8.72%
ROA
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 75.88%
ROIC
9.60% (13.19%) (2.68%) 7.21% (11.13%) (3.95%) (7.94%) 8.06% 2.60% 10.68%
ROE
predictions in italic, sparklines do not include predictions

All 10 years →

Fiscal years to Dec 2025 · latest quarter Mar 2026

Lakefront Biotherapeutics - Sponsored ADR peers in Biotechnology

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Lakefront Biotherapeutics - Sponsored ADR (LKFT) key facts

  • Lakefront Biotherapeutics - Sponsored ADR (LKFT) is a Biotechnology company in the Healthcare sector, traded in the US as an ADR.
  • Lakefront Biotherapeutics - Sponsored ADR’s revenue for fiscal 2025 (year ended December 2025) was EUR 1.3 billion, up 321.9% from fiscal 2024.
  • Net income was EUR 363.0 million, or EUR 5.51 per share (basic), a net margin of 28.9%.
  • As of September 25, 2026, LKFT traded at $29.38, a market capitalization of $2.0 billion.
  • Return on equity was 10.7% and debt-to-equity 0.00.

Source: company filings (standardised) and stockrow calculations.

Lakefront Biotherapeutics - Sponsored ADR (LKFT) Latest News

News by impact score

Fine-tune

23 Sep

3

RBC analysts see a meaningful opportunity for Lakefront Biotherapeutics' asset gamgertamig in rare autoimmune diseases, suggesting upside if development progresses. The excerpt provides no specifics on trial data, indications, timelines, or competitive context, and frames the note as market commentary rather than a company update. RBC's optimistic view signals upside but lacks concrete milestones or data in the available excerpt.

21 Sep

4

Lakefront Biotherapeutics plans registrational trials for gamgertamig in immune thrombocytopenia (ITP) and autoimmune hemolytic anemia (AIHA) in 2027, with two additional autoimmune-basket studies expected early that year. The company aims a short-course treatment intended to produce a durable immune reset by depleting B cells, as it pivots from legacy ex vivo CAR-T programs to four T-cell engager candidates after acquiring Ouro Medicines. Gilead Sciences will commercialize the lead program and Lakefront will receive royalties; Gilead also contributed funding to the Ouro deal. Lakefront projects year-end cash near €2 billion, supported by Gilead funding, legacy royalties and tax-credit receipts, and has largely completed its costly restructuring including a €50 million share buyback. Orphan Drug Designations were granted for ITP, AIHA and pemphigus. Ouro preclinical programs are now fully owned by Lakefront, with Gilead opt-in rights. Gilead-backed commercialization and a strong cash runway amid a pivot to four T-cell engagers could materially alter Lakefront's growth trajectory.

15 Sep

3

Lakefront Biotherapeutics - Sponsored ADR (LKFT) acquired its own shares. Share buyback by Lakefront Biotherapeutics can support stock price through reduced supply and signal management confidence.

24 Aug

4

U.S. FDA grants Orphan Drug Designation to Gamgertamig for Pemphigus treatment. Orphan Drug Designation confers regulatory incentives and market exclusivity that advance Gamgertamig development for Lakefront Biotherapeutics.

10 Aug

3

Lakefront Biotherapeutics released half-year 2026 financial results and a business update. Half-year financial results can moderately affect near-term share price and sentiment.

28 Jul

3

LKFT acquires own shares. Share buybacks moderately lift LKFT stock price and signal management confidence without altering core operations.

9 Jun

3

Lakefront Biotherapeutics initiates €50 million stock repurchase program for Sponsored ADR (LKFT). €50 million repurchase signals management confidence and can provide short-term share price support without altering long-term fundamentals.

7 Jun

4

Gilead Sciences and Lakefront Biotherapeutics acquire Ouro Medicines to advance autoimmune pipeline. Acquisition of Ouro Medicines delivers major strategic expansion for Lakefront Biotherapeutics autoimmune pipeline.

4 Jun

4

Gilead Sciences and Lakefront Biotherapeutics completed the acquisition of Ouro Medicines to expand the inflammation pipeline. Acquisition of Ouro Medicines delivers major strategic expansion to Lakefront's inflammation pipeline via Gilead partnership.

4

Gilead Sciences and Lakefront Biotherapeutics completed the acquisition of Ouro Medicines to expand the inflammation pipeline. Acquisition of Ouro Medicines represents major strategic move expanding Lakefront inflammation pipeline via Gilead partnership.

7 May

3

Galapagos NV (GLPG) Q1 earnings call highlights financial results, pipeline updates, strategic priorities, and outlook amid ongoing R&D efforts. Q1 earnings call highlights offer moderate insights into financials and pipeline, influencing sentiment but limited by lack of transformative announcements.

6 May

3

Galapagos NV (GLPG) reported first quarter 2026 financial results and provided a business update. Quarterly financial results and business updates affect financial performance and investor sentiment.

4 Apr

4

Galapagos NV (GLPG) signs agreement with Gilead on Ouro Medicines assets. Agreement with major pharma Gilead on Ouro Medicines assets signals a key strategic partnership likely boosting GLPG's pipeline, finances, and investor sentiment.

31 Mar

4

Galapagos NV partners with Gilead on gamgertamig, unlocking $500M cash infusion and targeting registrational trials in 2027. Gilead partnership delivers $500M cash and positions gamgertamig for 2027 trials, providing major financial boost and pipeline validation for GLPG.

4

Gilead Sciences expands autoimmune ambitions via deal with Ouro and collaboration with Galapagos NV (GLPG). Gilead collaboration validates Galapagos' autoimmune pipeline and signals major strategic partnership boosting future prospects.

4

Galapagos NV and Gilead enter binding agreement to collaborate on advancing first-in-class T cell engager program for autoimmune diseases. Binding collaboration with major pharma Gilead on innovative T cell engager validates GLPG pipeline and boosts revenue potential via milestones and royalties.

24 Mar

4

Gilead Sciences to acquire Ouro Medicines for $2.2 billion, positioning its 'Immune Reset' technology as central to future immunology successes. Gilead's $2.2 billion purchase of Ouro Medicines signals major investment in immunology, heightening competition and potentially shifting Galapagos NV's strategic outlook.

23 Mar

4

Galapagos NV (GLPG) and Gilead are in advanced discussions to collaborate on advancing a first-in-class T cell engager program for autoimmune diseases. Advanced collaboration with Gilead on a first-in-class T cell engager for autoimmune diseases signals a major strategic partnership that could significantly boost GLPG's pipeline and market performance.

6 Mar

4

Galapagos NV launches new subscription rights plan to offer shareholders rights to purchase additional shares. New subscription rights plan enables major capital raise, potentially transforming financial position and market trajectory.

24 Feb

4

Galapagos NV (GLPG) detailed strategic shifts and financial highlights in its Full Year 2025 earnings call. Strategic shifts in FY2025 earnings call represent major moves likely to alter GLPG's trajectory and investor sentiment.

4

Galapagos NV (GLPG) released highlights from its Q4 earnings call, covering financial results, pipeline updates, and strategic outlook. Q4 earnings highlights disclose financial performance, pipeline progress, and guidance that significantly shape investor sentiment and company trajectory.

23 Feb

4

Galapagos NV reported full year 2025 financial results and provided a fourth quarter business update. Full-year financial results and Q4 business update reveal key operational performance and pipeline progress, significantly affecting GLPG's valuation and investor outlook.

4 Feb

3

Third Arc Bio has announced a $52 million Series A extension aimed at expanding its oncology and immunology & inflammation portfolio. This funding will support the development of innovative therapies in these critical areas, enhancing the company's capabilities and market position. The funding could moderately influence Galapagos NV's competitive positioning in oncology and immunology, but its overall impact on the company's trajectory remains limited.

10 Jan

3

Galapagos NV reported mixed financial results, continuing to experience net losses despite some progress in its pipeline. The company's valuation is under scrutiny as investors weigh the implications of these results on future growth and market performance. Analysts are divided on the potential for recovery, with ongoing challenges in achieving profitability and the need for strategic adjustments. Mixed financial results and ongoing net losses indicate a moderately noticeable influence on future performance.

5 Jan

3

Galapagos NV has decided to wind down its cell therapy activities, a strategic move aimed at reallocating resources to other areas of its business. The company will cease operations related to its cell therapy programs and focus on its core therapeutic areas. This decision reflects a shift in priorities as Galapagos seeks to enhance its overall operational efficiency and financial health. Winding down cell therapy activities may moderately affect Galapagos' financial performance and product innovation.

18 Dec

4

Galapagos NV announced topline results from two Phase 3-enabling studies of its selective TYK2 inhibitor, GLPG3667, targeting dermatomyositis and systemic lupus erythematosus. The studies aim to evaluate the efficacy and safety of GLPG3667 in these autoimmune conditions, with results indicating potential for significant therapeutic benefits. The company plans to advance the development of GLPG3667 based on these findings, which could enhance its portfolio in the autoimmune disease market. Positive results from Phase 3-enabling studies could significantly impact Galapagos' future product offerings and market positioning in autoimmune diseases.

8 Dec

4

Galapagos NV presented new data on its ATALANTA-1 cell therapy for mantle cell lymphoma (MCL) at the ASH 2025 conference. The data highlights the therapy's efficacy and safety profile, showcasing promising results that could enhance treatment options for MCL patients. This presentation marks a significant step in Galapagos' ongoing research and development efforts in oncology. The new data on ATALANTA-1 cell therapy could significantly influence Galapagos' competitive positioning and market sentiment in the oncology sector.

11 Nov

3

Galapagos NV (GLPG) has experienced a recent uptick in share price, prompting discussions about its valuation. Analysts are evaluating whether the current price reflects the company's fundamentals and future prospects, considering recent developments in its pipeline and market conditions. Investors are advised to assess the sustainability of this price increase in light of the company's strategic direction and competitive landscape. The recent share price increase may influence investor sentiment and perceptions of the company's future performance, but it is not expected to fundamentally alter its trajectory.

6 Nov

4 transcript

Galapagos NV (GLPG) reported its Q3 2025 earnings, highlighting strategic shifts in its operations and product pipeline. The company is navigating challenges in the biotech landscape while focusing on innovation and partnerships to enhance its market position. Key financial metrics were discussed, alongside future outlooks and ongoing projects aimed at addressing unmet medical needs. Management emphasized the importance of adaptability in a rapidly changing environment, aiming to leverage new opportunities for growth. Significant strategic shifts and product developments could alter the company's trajectory and investor sentiment.

5 Nov

4

Galapagos NV reported its financial results for the first nine months of 2025, highlighting key metrics and developments in its business operations. The company provided updates on ongoing projects and strategic initiatives, indicating progress in its pipeline and financial health. Investors were informed about revenue figures, research advancements, and future outlook, reflecting the company's commitment to innovation and growth in the biopharmaceutical sector. Significant updates on financial performance and strategic initiatives are likely to influence investor sentiment and the company's future trajectory.

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