Monopar Therapeutics Inc. MNPR

85.24 (3.60) (4.05%) as of 25 Sep
Market cap
$602.8M
P/E
0.0×
Insider Buys alert about insiders buying in the last 12 month

Insider Decisions

Total buys 0.10
Total sells 1.15
in millions of $
Nov 25 Feb 26 May 26 Aug 26
Buy — — 1 — — — — — — — — —
Sell — — 1 — — — — — — — 3 —
Insider Ownership 53.76%

Capital & Financial Ratios

Market Cap 602.75
Revenue —
Net Income (17.84)
Free Cash Flow (12.18)
Net Debt (134.30)
Current Ratio 33.56
Debt/Equity 0.00
P/E ratio 0.00
P/S ratio 0.00
P/B ratio 5.56
Past 5Y EPS Growth (15.56%)
This Y EPS Growth (56.55%)
Next Y EPS Growth 14.97%
Next 5Y EPS Growth (0.20%)
in millions of $

Dividends

Payout Ratio 0.00
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2018 Powerpack
predictions in italic, special payouts not included in total or ratios

Assets vs Liabilities

2023 2024 2025 Q'26
Cash 7 60 140 134
Receivables — — — —
Inventory — — — —
Other 0 0 0 0
7 60 140 135
2023 2024 2025 Q'26
Payables 2 2 3 4
ST’ Debt — — — —
Other — 3 — —
2 5 3 4
in millions of $

Compound Annual Growth

10y 5y 3y
Sales — — —
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 54.43% 139.05%

Revenue

Year
in millions of $ · fiscal quarters ending in the months shown

Operating Cash Flow

Mar Jun Sep Dec Year
’26 (3) (3) — — —
’25 (6) (1) (2) (3) (12)
’24 (2) (2) (1) (2) (6)
’23 (2) (2) (2) (2) (8)
’22 (2) (1) (2) (1) (7)
’21 (2) (1) (2) (2) (7)
’20 (1) (1) (1) (1) (5)
in millions of $ · fiscal quarters ending in the months shown

Free Cash Flow

Mar Jun Sep Dec Year
’26 (3) (3) — — —
’25 (6) (1) (2) (3) (12)
’24 (2) (2) (1) (2) (6)
’23 (2) (2) (2) (2) (8)
’22 (2) (1) (2) (1) (7)
’21 (2) (1) (2) (2) (7)
’20 (1) (1) (1) (1) (5)
in millions of $ · fiscal quarters ending in the months shown

EPS

Mar Jun Sep Dec Year
’26 (0.46) (0.62) — — —
’25 (0.38) (0.35) (0.48) (0.61) (1.85)
’24 (0.50) (0.50) (0.37) (2.23) (4.11)
’23 (0.95) (0.80) (0.70) (0.60) (3.05)
’22 (0.95) (1.10) (0.95) (1.10) (4.15)
’21 (0.80) (0.85) (1.00) (1.05) (3.65)
’20 (0.50) (0.70) (0.74) (0.95) (2.90)
fiscal quarters ending in the months shown

Target Price Range

Analyst price targets

Recommendation Rating

1.3
1Buy 2 3Hold 4 5Sell
2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028
— — — 41.75 21.40 15.10 6.96 1.37 1.55 21.00

Analyst estimates 2026–2028

Powerpack
Low Price
— — — 240.00 115.00 85.05 24.40 19.10 38.50 105.00
High Price
— — 5 5 10 10 12 10 16 22
Employees
— — 0 0 0 0 0 0 0 0
Revenue/Emp
— — — — — — — — — —
Revenue
— — — — — — — — — —
Gross Margin
(1) (17) (3) (4) (6) (9) (11) (8) (16) (14)
EBT
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
EBT Margin
(1) (17) (3) (4) (6) (9) (11) (8) (16) (14)
Net Income
— — — — — — — — 0 (1)
Depreciation
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Revenue/Sh
(0.11) (9.43) (1.74) (2.25) (2.90) (3.65) (4.15) (3.05) (4.11) (1.85)
Earnings/Sh
(0.11) (1.50) (1.44) (1.62) (2.13) (2.93) (2.84) (2.84) (1.69) (1.65)
Cash Flow/Sh
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Capex/Sh
(0.11) (1.50) (1.44) (1.62) (2.13) (2.93) (2.84) (2.84) (1.69) (1.65)
Free CF/Sh
0.27 5.48 3.72 6.77 7.16 7.59 3.97 2.02 14.52 18.60
Book Value/Sh
11 2 2 2 2 2 3 3 4 7
Shares
— — — — — — — — — —
PE Ratio
— — — — — — — — — —
PS Ratio
— — — — — — — — — —
PB Ratio
— — — — — — — — — —
EV/Sales
— — — — — — — — — —
EV/FCF
(1) (3) (3) (3) (5) (7) (7) (8) (6) (12)
Op' Cash Flow
— — — — — — — — — —
Capex
(1) (3) (3) (3) (5) (7) (7) (8) (6) (12)
FCF
2 9 7 13 16 19 10 6 55 138
Working Cap'
— — — — — — 0 — — —
Total Debt
(2) (9) (7) (13) (17) (20) (13) (7) (60) (140)
Net Debt
3 10 7 13 16 19 10 6 55 138
Sh' Equity
(18.49%) (258.13%) (37.43%) (40.88%) (41.72%) (48.69%) (62.32%) (81.68%) (46.09%) (13.65%)
ROA
0.00% (1,627.75%) (8,132.57%) 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
ROIC
(19.05%) (265.94%) (39.04%) (43.23%) (44.52%) (52.57%) (72.44%) (107.19%) (51.42%) (14.22%)
ROE
predictions in italic, sparklines do not include predictions

All 10 years →

Monopar Therapeutics Inc. peers in Biotechnology

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Monopar Therapeutics Inc. (MNPR) key facts

  • Monopar Therapeutics Inc. (MNPR) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of September 25, 2026, MNPR traded at $85.24, a market capitalization of $602.8 million.
  • Return on equity was −14.2% and debt-to-equity 0.00.

Source: company filings (standardised) and stockrow calculations.

Monopar Therapeutics Inc. (MNPR) Latest News

News by impact score

Fine-tune

19 Aug

3

Monopar Therapeutics appoints Jeffrey D. Kent, M.D., as Executive Vice President and Head of Medical Affairs. Company also schedules two ALXN1840 presentations at AASLD – The Liver Meeting® 2026. Executive hire strengthens medical leadership while conference presentations signal pipeline progress with moderate market visibility.

22 Jul

4

Monopar Therapeutics initiates rolling NDA submission for ALXN1840 in Wilson Disease. Rolling NDA submission for ALXN1840 represents major regulatory milestone advancing Wilson Disease treatment and MNPR trajectory.

20 Jul

3

Monopar Therapeutics adds veteran commercial executive Nicole Sweeny to its Board of Directors and expands the commercial leadership team to advance launch readiness. Leadership additions for commercial launch strengthen execution capability but represent incremental rather than transformative change.

30 Jun

4

Monopar Therapeutics Inc. receives FDA Rare Pediatric Disease Designation for ALXN1840 for Wilson Disease treatment. FDA rare pediatric disease designation grants MNPR potential priority review voucher eligibility and accelerates ALXN1840 development path.

26 Jun

4

Monopar presents new analyses of Phase 3 FoCus data at EAN 2026 showing greater neurologic and global clinical benefit with ALXN1840 versus standard of care in Wilson disease. Positive Phase 3 data presentation supports potential regulatory progress and commercial prospects for ALXN1840 in Wilson disease.

1 Jun

4

Monopar Therapeutics presented Phase 2 ALXN1840 data at EASL 2026 demonstrating liver disease stabilization and neurologic improvement in treatment-experienced Wilson Disease patients. Positive Phase 2 data for ALXN1840 in Wilson Disease indicates major clinical progress likely to boost Monopar's trajectory and investor sentiment.

19 May

4

Monopar Therapeutics announces publication of Phase 2 study results showing ALXN1840 significantly improves copper balance in Wilson Disease patients. Positive Phase 2 publication for ALXN1840 advances MNPR's Wilson Disease program and can lift valuation and partnering prospects.

14 May

3

Monopar Therapeutics Inc. (MNPR) reported first quarter 2026 financial results and provided business updates. Quarterly financial results and business updates moderately influence financial performance and investor sentiment.

3 May

3

Monopar Therapeutics (NASDAQ:MNPR) is well-positioned to execute its growth plans. MNPR's strong setup for growth execution moderately boosts financial and market outlook.

19 Apr

5

Monopar Therapeutics Inc. (MNPR) presented Phase 3 data at AAN 2026 showing ALXN1840 delivers greater neurologic benefits than standard of care in Wilson Disease patients with neurologic symptoms. Positive Phase 3 data demonstrating ALXN1840 superiority in Wilson Disease neurologic symptoms positions MNPR for regulatory approval and transformative market growth.

27 Mar

3

Monopar Therapeutics Inc. (MNPR) reported fourth quarter and full-year 2025 financial results and provided a business update. Financial results and business updates for biotechs like Monopar can noticeably influence financial performance and market sentiment.

2 Mar

3

Monopar Therapeutics Inc. (MNPR) appointed Susan Rodriguez, a seasoned biopharma executive with over 25 years of experience, as Chief Commercial and Strategy Officer to expand its leadership team and support pipeline advancement. Appointment of experienced commercial leader strengthens Monopar's strategic positioning for pipeline commercialization.

11 Feb

3

Monopar Therapeutics Inc. (MNPR) experienced a US$66 million decrease in market capitalization last week, primarily attributed to institutional investors. Despite this short-term decline, long-term gains have positively impacted these investors, suggesting a potential recovery or growth in the future. The market cap decrease indicates some volatility, but long-term gains suggest stability and potential for recovery.

22 Dec

3

Monopar Therapeutics Inc. (MNPR) is highlighted among four biotech stocks that have seen significant gains in 2025, with its performance reflecting broader trends in the biotech sector. The article examines factors contributing to the stock's rise, including advancements in drug development and market dynamics that favor innovative biotech companies. Investors are keenly observing these stocks for potential future growth and strategic developments that could further enhance their market positions. The stock's performance is influenced by broader market trends and advancements in drug development, which may moderately affect its trajectory.

22 Nov

3

Monopar Therapeutics Inc. (MNPR) is currently trading at a 46% discount compared to its estimated fair value, raising questions about its market position. Analysts suggest that this discount may present a buying opportunity, especially given the company's focus on developing innovative cancer therapies. The stock's performance has been influenced by recent market trends and investor sentiment, leading to speculation about its future trajectory. The significant discount in trading price indicates potential for moderate influence on investor sentiment and market performance.

13 Nov

3

Monopar Therapeutics Inc. reported its financial results for the third quarter of 2025, highlighting key developments in its operations and financial performance. The company provided updates on its clinical programs and strategic initiatives aimed at advancing its pipeline. Financial metrics showed progress, with notable changes in revenue and expenses compared to previous quarters. Management expressed optimism about future growth and ongoing projects, emphasizing their commitment to innovation in therapeutic solutions. Financial results and updates on clinical programs indicate a moderately noticeable influence on the company's future performance.

9 Nov

4

Monopar Therapeutics Inc. presented new data at AASLD - The Liver Meeting® 2025, highlighting the rapid improvement of copper balance in Wilson Disease patients treated with Tiomolybdate Choline. The findings suggest significant therapeutic potential for Tiomolybdate Choline in managing Wilson Disease, a genetic disorder that leads to copper accumulation in the body. The presentation of new data indicating rapid improvement in a serious condition could significantly enhance Monopar's market position and investor sentiment.

21 Oct

4

Monopar Therapeutics Inc. (MNPR) is projected to potentially increase by 42.46% according to Wall Street analysts. The company's recent developments and strategic initiatives have garnered attention, leading to optimistic forecasts regarding its market performance. Investors are closely monitoring these projections as they could influence trading activity and sentiment surrounding the stock. Analysts' expectations of a significant price rally indicate a potential major impact on investor sentiment and market dynamics.

16 Oct

4

Raymond James has raised the price target for Monopar Therapeutics Inc. (MNPR) to $142 while maintaining a 'Strong Buy' rating. This adjustment reflects confidence in the company's potential and future performance in the market. The increase in price target indicates significant investor confidence and potential for substantial market impact.

15 Oct

3

Monopar Therapeutics Inc. announced that an abstract has been accepted for oral presentation at the AASLD - The Liver Meeting® 2025. This presentation will focus on the company's advancements and research related to liver diseases, highlighting its commitment to addressing unmet medical needs in this area. The acceptance of the abstract for presentation indicates progress in research that may enhance Monopar's competitive positioning and market perception.

23 Sep

4

Monopar Therapeutics Inc. announced that the Journal of Hepatology published a letter to the editor from physicians demonstrating that ALXN1840 rapidly improved copper balance in patients with Wilson Disease. This finding highlights the potential effectiveness of ALXN1840 in treating this condition, which is characterized by copper accumulation in the body. The publication of positive clinical findings for ALXN1840 could significantly enhance Monopar's market position and investor sentiment regarding its therapeutic offerings.

3

Monopar Therapeutics Inc. has announced the pricing of a $135 million underwritten offering of common stock and pre-funded warrants. The offering is expected to enhance the company's financial position and support its ongoing clinical development programs. The transaction is anticipated to close on or about October 30, 2023, subject to customary closing conditions. The capital raised will support clinical development, potentially influencing financial performance and market positioning.

15 Sep

4

Monopar Therapeutics Inc. (MNPR) has recently experienced a significant surge in its stock price, attributed to positive developments in its clinical trials and strategic partnerships. The company, recognized as a top 1% biotech stock, is gaining attention for its innovative approaches in cancer treatment. Investors are optimistic about its potential to deliver impactful therapies, which has contributed to the stock's breakout performance in the market. Positive clinical trial results and strategic partnerships are likely to significantly influence Monopar's future performance and investor sentiment.

14 Sep

4

Monopar Therapeutics Inc. will present new long-term neurological efficacy and safety data for ALXN1840, a treatment for Wilson Disease, at the 150th American Neurological Association Annual Meeting. This presentation aims to highlight the potential benefits and safety profile of ALXN1840, which could impact treatment options for patients with Wilson Disease. The presentation of new long-term data for ALXN1840 could significantly influence Monopar's market position and investor sentiment regarding its treatment for Wilson Disease.

3 Sep

3

Monopar Therapeutics Inc. announced that an abstract has been accepted with distinction for both oral and poster presentations at the American Neurological Association's 2025 Annual Meeting. This recognition highlights the significance of their research and contributions to the field of neurology. The acceptance of the abstract may enhance Monopar's visibility and credibility in the neurology sector, potentially influencing investor sentiment and future collaborations.

1 Sep

3

Monopar Therapeutics Inc. (MNPR) is highlighted among US high growth tech stocks to watch, indicating potential investor interest and market attention. The company is positioned within a competitive landscape that may influence its future performance and growth trajectory. The mention of Monopar in the context of high growth tech stocks suggests a moderately noticeable influence on its market sentiment and competitive positioning.

3

Monopar Therapeutics Inc. (MNPR) is highlighted among three high-growth tech stocks in the U.S. market, showcasing its potential for significant advancements in the biotech sector. The company focuses on developing innovative therapies for cancer treatment, which positions it favorably in a competitive landscape. Investors are encouraged to consider MNPR's growth trajectory as it navigates the complexities of the biotech industry, particularly in light of recent developments and market trends. Monopar's focus on innovative cancer therapies may moderately influence its financial performance and competitive positioning.

29 Aug

4

Monopar Therapeutics Inc. (MNPR) is highlighted among high-growth tech stocks to watch in August 2025, indicating potential investor interest and market momentum. The company is recognized for its innovative approaches in the biotech sector, which may lead to significant advancements and opportunities in the near future. Analysts suggest that MNPR's strategic initiatives could position it favorably within the competitive landscape, attracting attention from investors seeking growth in the technology and healthcare sectors. Strategic initiatives and innovations in the biotech sector are likely to significantly impact Monopar's future performance and investor sentiment.

3

Monopar Therapeutics Inc. (MNPR) is highlighted among US high growth tech stocks to watch in August 2025, reflecting its potential for significant market performance and investor interest. The company is positioned within a competitive landscape that may influence its future trajectory, particularly in the biotech sector. Investors are advised to monitor developments closely as they could impact MNPR's strategic direction and financial outcomes. Monopar Therapeutics is in a competitive biotech sector where developments may moderately influence its financial performance and market positioning.

28 Aug

4

Monopar Therapeutics Inc. (MNPR) is highlighted among high growth tech stocks in the US for August 2025, indicating strong market interest and potential for significant advancements in its operations and product offerings. The identification of Monopar as a high growth stock suggests significant market interest and potential strategic developments that could impact its future performance.

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