Monopar Therapeutics Inc.

MNPR Healthcare Biotechnology

In the quarter to June 2026, EPS fell 77.1% and free cash flow fell 201.4%, each against the same quarter a year earlier. Insiders bought in the last twelve months.

69.27 2.53 −3.52%
Market cap
$481.9M
P/E
0.0×
Fwd P/E
—
Dividend yield
—
F-score
n/a
Altman Z
n/a
Beneish M
n/a
Dividend safety
n/a

Insider Decisions trades per month

Total buys 0.10
Total sells 4.37
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — 1 — — — — — — — — — —
Sell — 1 — — — — — — — 3 1 1
Insider Ownership 53.87%

Capital & Financial Ratios $m

Market Cap 481.93
Revenue —
Net Income (17.84)
Free Cash Flow (12.18)
Net Debt (134.30)
Current Ratio 33.56 (at or above 1.5: strong)
Debt/Equity 0.00 (at or below 0.5: strong)
P/E ratio 0.00
Fwd P/E —
P/S ratio 0.00
P/B ratio 4.52
Past 5Y EPS Growth —
This Y EPS Growth (60.91%) (below 0%: weak)
Next Y EPS Growth 17.27% (at or above 15%: strong)
Next Y revenue growth —
Next 5Y EPS Growth (0.20%) (below 0%: weak)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/B against its own 10 years 72.24%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2018 Powerpack
special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 7 60 140 134
Receivables — — — —
Inventory — — — —
Other 0 0 0 0
7 60 140 135
2023 2024 2025 Q'26
Payables 2 2 3 4
ST’ Debt — — — —
Other — 3 — —
2 5 3 4

Compound Annual Growth %

10y 5y 3y
Sales — — —
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 54.43% 139.05%

Revenue $m

Year
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (3) (3) — — —
’25 (6) (1) (2) (3) (12)
’24 (2) (2) (1) (2) (6)
’23 (2) (2) (2) (2) (8)
’22 (2) (1) (2) (1) (7)
’21 (2) (1) (2) (2) (7)
’20 (1) (1) (1) (1) (5)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (3) (3) — — —
’25 (6) (1) (2) (3) (12)
’24 (2) (2) (1) (2) (6)
’23 (2) (2) (2) (2) (8)
’22 (2) (1) (2) (1) (7)
’21 (2) (1) (2) (2) (7)
’20 (1) (1) (1) (1) (5)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.46) (0.62) — — —
’25 (0.38) (0.35) (0.48) (0.61) (1.85)
’24 (0.50) (0.50) (0.37) (2.23) (4.11)
’23 (0.95) (0.80) (0.70) (0.60) (3.05)
’22 (0.95) (1.10) (0.95) (1.10) (4.15)
’21 (0.80) (0.85) (1.00) (1.05) (3.65)
’20 (0.50) (0.70) (0.74) (0.95) (2.90)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.3
1Buy 2 3Hold 4 5Sell

Ten years at a glance

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low — — — 41.75 21.40 15.10 6.96 1.37 1.55 21.00

Analyst estimates 2026–2028

Powerpack
High — — — 240.00 115.00 85.05 24.40 19.10 38.50 105.00
People
People Employees — — 5 5 10 10 12 10 16 22
Revenue/emp, $m — — 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Income, $m
Income, $m Revenue — — — — — — — — — —
Gross margin, % — — — — — — — — — —
EBT (1) (17) (3) (4) (6) (9) (11) (8) (16) (14)
EBT margin, % 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Net income (1) (17) (3) (4) (6) (9) (11) (8) (16) (14)
Depreciation — — — — — — — — 0 (1)
Per share, $
Per share, $ Revenue 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Earnings (0.11) (9.43) (1.74) (2.25) (2.90) (3.65) (4.15) (3.05) (4.11) (1.85)
Cash flow (0.11) (1.50) (1.44) (1.62) (2.13) (2.93) (2.84) (2.84) (1.69) (1.65)
Capex 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Free cash flow (0.11) (1.50) (1.44) (1.62) (2.13) (2.93) (2.84) (2.84) (1.69) (1.65)
Book value 0.27 5.48 3.72 6.77 7.16 7.59 3.97 2.02 14.52 18.60
Shares, m 11 2 2 2 2 2 3 3 4 7
Valuation, ×
Valuation, × P/E — — — — — — — — — —
P/S — — — — — — — — — —
P/B — — — — — — — — — —
EV/Sales — — — — — — — — — —
EV/FCF — — — — — — — — — —
Cash, $m
Cash, $m Operating cash flow (1) (3) (3) (3) (5) (7) (7) (8) (6) (12)
Capex — — — — — — — — — —
Free cash flow (1) (3) (3) (3) (5) (7) (7) (8) (6) (12)
Balance, $m
Balance, $m Working capital 2 9 7 13 16 19 10 6 55 138
Total debt — — — — — — 0 — — —
Net debt (2) (9) (7) (13) (17) (20) (13) (7) (60) (140)
Shareholders’ equity 3 10 7 13 16 19 10 6 55 138
Returns, %
Returns, % ROA (18.49) (258.13) (37.43) (40.88) (41.72) (48.69) (62.32) (81.68) (46.09) (13.65)
ROIC 0.00 (1,627.75) (8,132.57) 0.00 0.00 0.00 0.00 0.00 0.00 0.00
ROE (19.05) (265.94) (39.04) (43.23) (44.52) (52.57) (72.44) (107.19) (51.42) (14.22)
Negative figures in brackets.

All 10 years →

Charts ten years each

Monopar Therapeutics Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
MNPR Monopar Therapeutics Inc. $481.9M — (loss-making) — — n/m −201.41% (below 0%: shrinking) — 0.00%
ENTX Entera Bio Ltd. $481.5M — (loss-making) — (loss-making) +200.00% (above 0%: growing) n/m −108.86% (below 0%: shrinking) 0.00% 0.00% Compare
NGNE Neurogene Inc. $479.3M — (loss-making) — (loss-making) — n/m −22.97% (below 0%: shrinking) 100.00% 0.00% Compare
YDES YD Bio Limited $477.5M — — — — — — — Compare
RGNX REGENXBIO Inc. $472.7M — (loss-making) — (loss-making) +405.73% (above 0%: growing) n/m −26.67% (below 0%: shrinking) 99.04% 27.09% Compare
ARVN Arvinas, Inc. $468.2M 53.6× — (loss-making) +1,014.73% (above 0%: growing) n/m +49.79% (above 0%: growing) 96.40% 65.72% Compare
CBIO Crescent Biopharma, Inc. $463.6M — (loss-making) — (loss-making) +1,038,900.00% (above 0%: growing) n/m −7.04% (below 0%: shrinking) 100.00% 0.00% Compare
ALLO Allogene Therapeutics, Inc. $463.0M — (loss-making) — (loss-making) +20,990.91% (above 0%: growing) n/m +17.73% (above 0%: growing) 100.00% (1,011.21%) Compare
ALT Altimmune, Inc. $459.1M — (loss-making) — (loss-making) +520.00% (above 0%: growing) n/m −25.27% (below 0%: shrinking) 100.00% 0.00% Compare
Median of peers $470.4M — — +767.37% — −22.97% 100.00% 0.00%

All 614 Biotechnology stocks →

Monopar Therapeutics Inc. (MNPR) key facts

  • Monopar Therapeutics Inc. (MNPR) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, MNPR traded at $69.27, a market capitalization of $481.9 million.
  • Return on equity was −14.2% and debt-to-equity 0.00.

Source: company filings (standardised) and stockrow calculations.

Monopar Therapeutics Inc. (MNPR) Latest News

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