Pyxis Oncology, Inc. PYXS
- Market cap
- $250.2M
- P/E
- 0.0×
Follow PYXS
Target Price Range
Analyst price targets
Free account| 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | 2026 | 2027 | 2028 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| — | — | — | — | — | 7.90 | 1.10 | 1.34 | 1.49 | 0.83 |
Analyst estimates 2026–2028 Powerpack |
Low Price
|
||
| — | — | — | — | — | 19.00 | 11.50 | 6.92 | 6.85 | 5.55 |
High Price
|
|||
| — | — | — | — | — | 56 | 75 | 50 | 44 | 56 |
Employees
|
|||
| — | — | — | — | — | 0 | 0 | 0 | 0 | 0 |
Revenue/Emp
|
|||
| — | — | — | — | — | — | — | — | 16 | 14 |
Revenue
|
|||
| — | — | — | — | 0.00% | 0.00% | 0.00% | — | 97.06% | 82.77% |
Gross Margin
|
|||
| — | — | — | (3) | (13) | (76) | (121) | (74) | (79) | (78) |
EBT
|
|||
| — | — | — | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | (492.35%) | (564.55%) |
EBT Margin
|
|||
| — | 0 | — | (3) | (13) | (76) | (121) | (74) | (77) | (80) |
Net Income
|
|||
| — | — | — | — | 0 | 1 | 1 | (3) | (3) | 2 |
Depreciation
|
|||
| — | — | — | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.22 |
Revenue/Sh
|
|||
| — | — | — | (0.08) | (12.44) | (8.95) | (3.65) | (1.85) | (1.32) | (1.28) |
Earnings/Sh
|
|||
| — | — | — | (0.07) | (9.78) | (4.16) | (2.70) | (1.77) | (0.99) | (1.02) |
Cash Flow/Sh
|
|||
| — | — | — | 0.00 | (1.44) | (0.06) | (0.19) | (0.17) | 0.00 | 0.00 |
Capex/Sh
|
|||
| — | — | — | (0.07) | (11.22) | (4.22) | (2.90) | (1.94) | (0.99) | (1.02) |
Free CF/Sh
|
|||
| — | — | — | 0.56 | (15.17) | 30.77 | 4.87 | 3.15 | 2.07 | 0.86 |
Book Value/Sh
|
|||
| — | — | — | 34 | 1 | 8 | 33 | 40 | 58 | 62 |
Shares
|
|||
| — | — | — | — | — | — | — | — | 0.00 | 0.00 |
PE Ratio
|
|||
| — | — | — | — | — | — | — | — | 0.00 | 0.00 |
PS Ratio
|
|||
| — | — | — | — | — | — | — | — | 0.76 | 1.34 |
PB Ratio
|
|||
| — | — | — | — | — | — | — | — | 0.00 | 0.00 |
EV/Sales
|
|||
| — | — | — | — | — | — | — | — | 0.64 | (0.05) |
EV/FCF
|
|||
| — | — | — | (2) | (10) | (35) | (89) | (71) | (58) | (64) |
Op' Cash Flow
|
|||
| — | — | — | — | (1) | (1) | (6) | (7) | 0 | 0 |
Capex
|
|||
| — | — | — | (2) | (12) | (36) | (96) | (77) | (58) | (64) |
FCF
|
|||
| — | — | — | 19 | 4 | 260 | 155 | 99 | 115 | 51 |
Working Cap'
|
|||
| — | — | — | 0 | 1 | 0 | 19 | — | — | — |
Total Debt
|
|||
| — | — | — | (20) | (8) | (276) | (181) | (121) | (128) | (68) |
Net Debt
|
|||
| — | — | — | 19 | (16) | 261 | 161 | 126 | 121 | 53 |
Sh' Equity
|
|||
| — | — | — | (27.99%) | (85.64%) | (52.37%) | (49.13%) | (38.32%) | (46.74%) | (64.03%) |
ROA
|
|||
| — | — | — | 0.00% | 0.00% | 0.00% | 0.00% | (1,041.19%) | 0.00% | 0.00% |
ROIC
|
|||
| — | — | — | 29.94% | 138.54% | (61.85%) | (57.19%) | (51.51%) | (62.75%) | (91.43%) |
ROE
|
|||
Pyxis Oncology, Inc. peers in Biotechnology
| Company | Market cap | P/E | Compare |
|---|---|---|---|
| ACIU AC Immune | $249.4M | 0.0× | Compare |
| LYEL Lyell Immunopharma, Inc. | $248.0M | 0.0× | Compare |
| YARW Yarrow Bioscience, Inc | $246.0M | 0.0× | Compare |
| TRDA Entrada Therapeutics, Inc. | $242.2M | 0.0× | Compare |
| Company | Market cap | P/E | Compare |
|---|---|---|---|
| MGNX MacroGenics, Inc. | $242.1M | 0.0× | Compare |
| SION Sionna Therapeutics, Inc. | $241.9M | 0.0× | Compare |
| CAMP CAMP4 Therapeutics Corporation | $241.0M | 0.0× | Compare |
| ZNTL Zentalis Pharmaceuticals, Inc. | $260.4M | 0.0× | Compare |
Pyxis Oncology, Inc. (PYXS) key facts
- Pyxis Oncology, Inc. (PYXS) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
- Pyxis Oncology, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $13.9 million, down 14.2% from fiscal 2024.
- As of September 25, 2026, PYXS traded at $2.86, a market capitalization of $250.2 million.
- Return on equity was −91.4% and debt-to-equity 0.00.
Pyxis Oncology, Inc. (PYXS) Latest News
9 Sep
Pyxis Oncology announces positive updated data from Phase 1 monotherapy study of Micvotabart Pelidotin in 2L+ recurrent/metastatic head and neck squamous cell carcinoma. Positive Phase 1 data for lead asset in major indication advances clinical pipeline and strengthens competitive position.
8 Sep
Pyxis Oncology will host a webcast to present updated Phase 1 monotherapy data on Micvotabart Pelidotin in second-line and beyond recurrent/metastatic head and neck squamous cell carcinoma. Phase 1 data updates on a lead oncology candidate can drive major shifts in valuation and investor sentiment for the company.
Pyxis Oncology appoints Thomas Civik as Chief Executive Officer and Chairman of the Board. New CEO and chairman appointment positions Thomas Civik to drive strategic shifts at Pyxis Oncology.
13 Aug
Pyxis Oncology reported second quarter 2026 financial results and advanced MICVO toward key 2026 clinical milestones. Routine quarterly results paired with pipeline progress signal moderate effects on operations and sentiment.
30 Jun
Pyxis Oncology secures up to $114 million through private placement financing. Large capital raise materially extends cash runway and funds pipeline advancement.
Pyxis Oncology announces up to $114 million private placement financing to advance MICVO through key clinical milestones. Major financing round supplies capital needed to reach pivotal clinical milestones and materially improves financial runway.
10 Jun
Analysts forecast nearly 3X upside for Pyxis Oncology (PYXS) shares. Analyst upside projections may lift short-term PYXS sentiment without altering core operations.
14 May
Pyxis Oncology reported first quarter 2026 financial results and advanced MICVO toward key clinical milestones in 2026. MICVO advancement to key 2026 milestones signals major pipeline progress with potential to significantly alter trajectory and investor sentiment.
7 May
Pyxis Oncology, Inc. (PYXS) appoints Nelson Azoulay as Chief Business Officer to lead business development, partnerships, and strategic growth initiatives. Appointing a Chief Business Officer bolsters leadership for partnerships and strategic expansion in oncology drug development.
23 Mar
Pyxis Oncology, Inc. (PYXS) provided a business update and reported fourth quarter and full year 2025 financial results. Business updates paired with quarterly and annual financial results significantly shape investor sentiment and stock trajectory.
6 Feb
Pyxis Oncology, Inc. (PYXS) is highlighted among three penny stocks with market capitalizations exceeding $50 million. The company focuses on developing innovative cancer therapies, particularly in the field of immuno-oncology. Investors are encouraged to monitor its progress and potential market movements as it navigates the competitive landscape of biotechnology. The company's focus on innovative cancer therapies may moderately influence its financial performance and competitive positioning.
3 Feb
Pyxis Oncology, Inc. has appointed an interim CEO as part of a leadership transition aimed at enhancing strategic focus and ensuring program continuity. This move is intended to align the company's operations with its long-term goals and improve overall performance. Leadership transitions can moderately influence company operations and market sentiment, impacting strategic direction and execution.
7 Jan
Pyxis Oncology, Inc. (PYXS) is highlighted as one of three promising penny stocks with market caps up to $300 million. The company focuses on developing innovative cancer therapies, particularly its proprietary antibody-drug conjugate platform. Investors are drawn to its potential for significant growth, especially as it advances its clinical trials and partnerships. The article emphasizes the importance of monitoring market trends and company developments for potential investment opportunities. The company's advancements in cancer therapies may moderately influence its financial performance and market positioning.
18 Dec
Pyxis Oncology, Inc. announced positive preliminary Phase 1 data for Micvotabart Pelidotin (MICVO) in patients with recurrent or metastatic head and neck squamous cell carcinoma. The results indicate promising efficacy and safety profiles, suggesting potential for further development in this challenging cancer type. The company plans to advance the clinical program based on these findings. Positive Phase 1 data could significantly enhance Pyxis Oncology's product pipeline and investor sentiment.
9 Dec
Pyxis Oncology, Inc. (PYXS) is highlighted as one of three promising penny stocks with a market cap exceeding $90 million. The company focuses on developing innovative cancer therapies, positioning itself in a competitive market. Investors are encouraged to consider its potential for growth amidst ongoing advancements in oncology treatments. The company's focus on innovative cancer therapies may moderately influence its financial performance and competitive positioning.
4 Nov
Pyxis Oncology, Inc. (PYXS) is highlighted among promising penny stocks to watch, alongside two other companies. The article emphasizes the potential for growth in the biotech sector, particularly for firms like Pyxis that are focused on innovative cancer therapies. Investors are encouraged to monitor these stocks closely due to their speculative nature and the ongoing developments in their respective fields. Pyxis Oncology's focus on innovative cancer therapies may moderately influence its market performance and investor sentiment.
3 Nov
Pyxis Oncology, Inc. provided a business update alongside its financial results for the third quarter of 2025, highlighting key developments in its pipeline and financial performance. The company reported progress in its clinical trials and outlined strategic initiatives aimed at enhancing its market position. Financial results indicated a focus on managing expenses while advancing its research and development efforts. The financial results and updates on clinical trials suggest a moderate influence on the company's future performance and market sentiment.
14 Oct
Pyxis Oncology, Inc. (PYXS) has been upgraded to a Strong Buy rating by analysts, reflecting increased confidence in the company's growth potential and strategic direction. This upgrade is based on positive developments in their pipeline and market positioning, suggesting that investors may see significant returns in the near future. The upgrade is expected to enhance investor sentiment and could lead to increased trading activity in PYXS shares. The upgrade to Strong Buy indicates a significant shift in investor sentiment and confidence in the company's future performance.
Pyxis Oncology, Inc. (PYXS) is highlighted among five small drug stocks poised for potential growth as the pharmaceutical industry shows signs of recovery. The article emphasizes the company's innovative approaches in oncology and its strategic positioning within a revitalizing market, suggesting that investors may find opportunities in these smaller firms as larger companies face challenges. The company's innovative strategies in oncology may moderately influence its competitive positioning and financial performance.
13 Oct
Pyxis Oncology, Inc. will present new translational data and key biological findings that clarify the mechanism of action of its drug MICVO at upcoming medical meetings. These findings are expected to enhance understanding of the drug's efficacy and potential applications in oncology. The presentation of significant translational data and biological findings could lead to major strategic moves and influence investor sentiment.
9 Oct
Pyxis Oncology, Inc. has appointed Alex Kane as the Senior Vice President of Investor Relations and Capital Markets. Kane brings extensive experience in investor relations and capital markets, having previously held senior roles at various biotech firms. His appointment is expected to enhance Pyxis Oncology's engagement with investors and support its strategic initiatives. The appointment of a seasoned executive in investor relations may moderately influence market sentiment and operational aspects.
1 Oct
Maxion Therapeutics has appointed Joel Edwards as Chief Business Officer, bringing extensive experience in business development and commercialization in the biotech sector. Edwards previously held leadership roles at several biopharmaceutical companies, where he successfully advanced product pipelines and strategic partnerships. His appointment is expected to enhance Maxion's growth strategy and operational capabilities as the company focuses on developing innovative therapies. The appointment of a seasoned executive like Joel Edwards may positively influence Maxion's strategic direction and operational efficiency, but its direct impact on Pyxis Oncology's performance is limited.
15 Sep
Pyxis Oncology, Inc. (PYXS) has recently experienced a 'Golden Cross' in its stock chart, a technical indicator suggesting potential bullish momentum. This pattern occurs when a stock's short-term moving average crosses above its long-term moving average, often signaling a shift in market sentiment. Investors are evaluating whether this technical signal warrants a buy, considering the company's ongoing developments and market conditions. The Golden Cross indicates potential positive momentum, but its impact on long-term performance remains uncertain.
5 Sep
Pyxis Oncology, Inc. (PYXS) is highlighted as a promising penny stock opportunity for September 2025, with potential for significant growth driven by its innovative cancer therapies and strategic partnerships. The company is focusing on advancing its pipeline and enhancing shareholder value, positioning itself favorably in the competitive oncology market. Investors are encouraged to consider PYXS as a viable option for their portfolios, given its recent developments and market potential. Significant advancements in cancer therapies and strategic partnerships could greatly enhance Pyxis Oncology's market position and investor sentiment.
14 Aug
Pyxis Oncology, Inc. reported its financial results for the second quarter of 2025, highlighting key metrics and developments in its business operations. The company provided updates on its ongoing projects and strategic initiatives, reflecting its focus on advancing its pipeline and enhancing shareholder value. Financial performance indicators showed trends that may influence future growth and market positioning. The financial results and business updates indicate moderate influences on Pyxis Oncology's future performance and market sentiment.
2 Aug
Pyxis Oncology, Inc. is urged to approach its business growth cautiously as it navigates the complexities of the biotechnology sector. The company faces challenges in maintaining investor confidence and achieving sustainable development amid a competitive landscape. Strategic decisions will be crucial for its future performance and market positioning. Cautious growth strategies may moderately influence Pyxis Oncology's financial performance and competitive positioning.
19 Jun
Pyxis Oncology, Inc. (NASDAQ:PYXS) experienced an 11% stock decline, disappointing insiders who invested US$174.4k at an average price of US$1.96. Their investment is now valued at US$101.3k. CFO & COO Pamela Connealy made the largest insider purchase of US$174k at US$2.00 per share, indicating confidence in the company despite the current lower price of US$1.14. Insiders own 6.3% of the company, valued at US$4.6m, but higher ownership levels are preferred. No insider transactions occurred in the last quarter, and while past transactions are encouraging, there are concerns about the company's risks, including four warning signs. Insider purchases suggest some confidence in the company's future, but the overall ownership level is low and recent stock performance raises concerns.
15 May
Pyxis Oncology, Inc. reported its financial results for the first quarter of 2025, highlighting key developments in its business operations. The company provided updates on its ongoing clinical trials and strategic initiatives aimed at advancing its pipeline of cancer therapies. Financial metrics showed progress, with increased revenue and reduced losses compared to the previous quarter. Management expressed optimism about upcoming milestones and the potential impact of their innovative treatments on patient outcomes. Significant advancements in clinical trials and strategic initiatives could notably influence the company's future performance and market position.
25 Apr
Pyxis Oncology, Inc. presented preclinical data supporting micvotabart pelidotin (MICVO), an antibody-drug conjugate targeting EDB+FN, at the AACR Annual Meeting 2025. The data indicate MICVO's efficacy in tumor clearance and immune activation across various models, with a unique mechanism involving direct tumor killing and immunogenic cell death. Combination therapy with anti-PD-1 showed enhanced tumor clearance compared to monotherapy. MICVO is currently in Phase 1 studies for advanced solid tumors, including recurrent head and neck squamous cell carcinoma. The robust preclinical results and ongoing clinical studies for MICVO indicate significant potential for altering treatment approaches in difficult-to-treat cancers.
2 Apr
Pyxis Oncology, Inc. (Nasdaq: PYXS) announced that Dr. Lara S. Sullivan will participate in a fireside chat at the Stifel 2025 Virtual Targeted Oncology Forum on April 9, 2025, at 11:30 a.m. ET. The company will also hold one-on-one investor meetings during the event. A live webcast and replay will be available on their Investor Relations website. Pyxis Oncology is focused on developing next-generation therapeutics for difficult-to-treat cancers, with its lead product candidate, MICVO, targeting recurrent and metastatic head and neck squamous cell carcinoma (R/M HNSCC). MICVO aims to directly kill cancer cells and mobilize an anti-tumor immune response. Participation in a significant oncology forum may enhance investor interest and visibility for Pyxis Oncology's product development.