Promis Neurosciences PMN

11.27 (0.30) (2.59%) as of 25 Sep
Market cap
$103.8M
P/E
0.0×
Insider Buys alert about insiders buying in the last 12 month

Insider Decisions

Total buys 8.76
in millions of $
Nov 25 Feb 26 May 26 Aug 26
Buy 1 — — — 2 2 1 — — — 1 —
Sell — — — — — — — — — — — —
Insider Ownership 23.11%

Capital & Financial Ratios

Market Cap 103.76
Revenue 0.00
Net Income (42.23)
Free Cash Flow (42.11)
Net Debt (53.46)
Current Ratio 7.85
Debt/Equity 0.00
P/E ratio 0.00
P/S ratio 46,834.02
P/B ratio 2.09
Past 5Y EPS Growth 11.39%
This Y EPS Growth 77.42%
Next Y EPS Growth 25.36%
Next 5Y EPS Growth 47.73%
in millions of $

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2026 Powerpack
2025 Powerpack
2024 Powerpack
2023 Powerpack
predictions in italic, special payouts not included in total or ratios

Assets vs Liabilities

2023 2024 2025 Q'26
Cash 13 13 6 53
Receivables — — — —
Inventory — — — —
Other — — — —
14 19 9 57
2023 2024 2025 Q'26
Payables 8 2 3 2
ST’ Debt — — — —
Other — — — —
9 2 10 7
in millions of $

Compound Annual Growth

10y 5y 3y
Sales — — (44.49%)
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 0.00% 0.00%

Revenue

Mar Jun Sep Dec Year
’26 — — — — —
’20 — 0 — 0 0
’19 — 0 0 0 0
’18 0 — 0 0 0
’17 0 — 0 — 0
in millions of $ · fiscal quarters ending in the months shown
value withheld pending a data check

Operating Cash Flow

Mar Jun Sep Dec Year
’26 (12) (10) — — —
’25 (5) (4) (10) (9) (28)
’24 (10) (2) (7) (9) (27)
’23 (3) (2) (2) (4) (11)
’22 (3) (4) (5) (5) (17)
’21 (1) (1) (3) (4) (9)
’20 (1) (1) (1) (1) (3)
in millions of $ · fiscal quarters ending in the months shown

Free Cash Flow

Mar Jun Sep Dec Year
’26 (12) (10) — — —
’25 (5) (4) (10) (9) (28)
’24 (10) (2) (7) (9) (27)
’23 (3) (2) (2) (4) (11)
’22 (3) (4) (5) (5) (17)
’21 (1) (1) (3) (4) (9)
’20 (1) (1) (1) (1) (3)
in millions of $ · fiscal quarters ending in the months shown

EPS

Mar Jun Sep Dec Year
’26 (1.26) (1.28) — — —
’25 (5.25) (7.25) (6.00) (4.15) (22.61)
’24 (4.75) (3.25) 7.75 (0.50) 2.75
’23 (14.50) (6.75) (4.75) (2.25) (26.75)
’22 (7.28) (9.50) (21.25) (22.50) (60.25)
’21 (29.94) (1.11) (5.11) 0.00 (42.30)
’20 (7.07) (6.26) (6.07) (2.76) (22.16)
fiscal quarters ending in the months shown

Target Price Range

Analyst price targets

Recommendation Rating

1
1Buy 2 3Hold 4 5Sell
2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028
60.00 165.00 210.00 180.00 75.00 90.00 105.00 23.75 21.75 6.27

Analyst estimates 2026–2028

Powerpack
Low Price
240.00 1,050.00 885.00 510.00 345.00 345.00 245.00 223.75 77.50 39.75
High Price
— — — — — — 7 7 8 11
Employees
0 0 0 0 0 — 0 0 0 0
Revenue/Emp
0 0 0 0 0 — — — — —
Revenue
100.00% 100.00% 100.00% 100.00% 100.00% 0.00% 0.00% — — —
Gross Margin
(3) (5) (8) (6) (4) (10) (18) (13) 3 (40)
EBT
(130,460.00%) (61,102.63%) (1,960,975.00%) (619,311.11%) (325,153.85%) 0.00% 0.00% 0.00% 0.00% 0.00%
EBT Margin
(3) (5) (8) (6) (4) (10) (18) (13) 3 (40)
Net Income
0 0 0 0 0 0 0 0 — —
Depreciation
0.02 0.06 0.00 0.01 0.01 0.00 0.00 0.00 0.00 0.00
Revenue/Sh
(22.99) (29.94) (44.91) (29.94) (22.16) (42.30) (60.25) (26.75) 2.75 (22.61)
Earnings/Sh
(16.93) (31.97) (41.73) (26.45) (17.04) (40.21) (56.76) (22.05) (26.21) (16.00)
Cash Flow/Sh
0.00 0.00 0.00 0.00 (0.43) 0.40 (0.01) 0.00 0.00 0.00
Capex/Sh
(16.93) (31.97) (41.73) (26.45) (17.46) (39.81) (56.77) (22.05) (26.21) (16.00)
Free CF/Sh
0.46 8.60 5.58 1.73 (3.97) 24.46 (4.49) 7.63 15.90 (0.72)
Book Value/Sh
0 0 0 0 0 0 0 0 1 2
Shares
0.00 0.00 0.00 0.00 0.00 — — — — —
PE Ratio
0.00 0.00 159,800.00 30,756.82 10,407.27 — — — — —
PS Ratio
0.00 27.90 53.74 112.78 0.00 — — — — —
PB Ratio
0.00 0.00 153,547.67 29,589.73 10,043.86 — — — — —
EV/Sales
0.00 (7.20) (6.91) (7.09) (6.80) — — — — —
EV/FCF
(2) (4) (7) (5) (3) (9) (17) (11) (27) (28)
Op' Cash Flow
— — — — 0 0 0 — — —
Capex
(2) (4) (7) (5) (3) (9) (17) (11) (27) (28)
FCF
0 1 1 0 (1) 17 0 4 17 (1)
Working Cap'
— — — — — 4 — — — —
Total Debt
(1) (1) (2) (1) (1) (13) (6) (13) (13) (6)
Net Debt
0 1 1 0 (1) 6 (1) 4 16 (1)
Sh' Equity
0.00% (386.10%) (395.87%) (289.47%) (325.59%) (104.26%) (146.42%) (128.63%) 17.08% (282.76%)
ROA
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% (332.40%) 0.00%
ROIC
0.00% (751.91%) (756.07%) (935.12%) 1,844.24% (399.46%) (837.71%) (1,098.52%) 27.46% (521.61%)
ROE
predictions in italic, sparklines do not include predictions

All 10 years →

Fiscal years to Dec 2020 · latest quarter Dec 2020

Promis Neurosciences peers in Biotechnology

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Promis Neurosciences (PMN) key facts

  • Promis Neurosciences (PMN) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of September 25, 2026, PMN traded at $11.27, a market capitalization of $103.8 million.
  • Return on equity was −521.6% and debt-to-equity 0.00.

Source: company filings (standardised) and stockrow calculations.

Promis Neurosciences (PMN) Latest News

News by impact score

Fine-tune

14 Aug

4 transcript

ProMIS Neurosciences reported Q2 2026 earnings call highlights showing zero ARIA-E cases in its clinical developments. Zero ARIA-E cases signal strong safety data that can drive major gains in investor sentiment and company valuation.

13 Aug

3

Promis Neurosciences Q2 earnings call covered financial results, cash runway into 2025, and pipeline progress on PMN310 for Alzheimer's plus other neurodegenerative candidates. Quarterly earnings and pipeline updates can shift near-term sentiment and valuation but rarely alter long-term company trajectory.

3

ProMIS Neurosciences reported second quarter 2026 financial results and corporate highlights. Quarterly results and highlights supply performance data that can shift investor views and valuation.

28 Jul

4

Promis Neurosciences reports no ARIA-E in interim data from PMN310 Alzheimer’s trial. Absence of ARIA-E in Alzheimer’s trial interim data strengthens PMN310 safety profile and may lift company trajectory.

4

ProMIS Neurosciences shares climb after positive interim safety results from its Alzheimer’s trial. Positive interim Alzheimer’s trial safety data can drive major shifts in market performance and company trajectory.

4

ProMIS Neurosciences reported positive blinded six-month interim safety and biomarker data for PMN310 in the PRECISE-AD Phase 1b Alzheimer’s Disease Trial. Positive six-month interim data for lead candidate PMN310 in Alzheimer’s advances the program and boosts prospects.

14 Jul

4

ProMIS Neurosciences reported first human evidence of PMN310 target engagement with amyloid-beta oligomers at AAIC 2026. First human target engagement data for PMN310 marks a key clinical milestone that can materially advance the Alzheimer's program and lift company valuation.

12 Jun

3

Promis Neurosciences (PMN) rating upgraded to Buy. Buy rating upgrade may lift near-term investor sentiment and share price for Promis Neurosciences.

12 May

3

ProMIS Neurosciences announced first quarter 2026 financial results and corporate highlights. Quarterly financial results and corporate highlights moderately influence financial performance and investor sentiment.

30 Apr

3

Phoenix Mecano (VTX:PMN) reported soft earnings likely explained by conservative accounting practices. Soft earnings attributed to conservative accounting moderately influences financial performance and investor sentiment.

25 Mar

3

ProMIS Neurosciences announced full year 2025 financial results and provided corporate highlights. Annual financial results and corporate highlights moderately influence financial performance and investor sentiment.

18 Mar

3

ProMIS Neurosciences to present data on ALS and Parkinson's disease programs at the Alzheimer’s Disease/Parkinson’s Disease 2026 International Conference (AD/PD™). Data presentation at a major conference highlights pipeline progress in neurodegenerative diseases, likely boosting visibility and moderate investor sentiment without transformative immediate effects.

4 Feb

3

ProMIS Neurosciences will participate in the Guggenheim Emerging Outlook: Biotech Summit 2026, highlighting its commitment to engaging with investors and stakeholders in the biotechnology sector. This event is expected to provide insights into the company's strategic direction and innovations in neuroscience. Participation in a prominent biotech summit may enhance visibility and investor interest, but the overall impact on the company's trajectory is expected to be limited.

30 Jan

4

ProMIS Neurosciences announced a private placement financing of up to $175 million to support its development of therapies for neurodegenerative diseases. The financing is expected to enhance the company's financial position and accelerate its clinical programs. ProMIS aims to leverage its proprietary technology platform to advance its pipeline, which includes treatments for Alzheimer's disease and other related conditions. The financing will significantly bolster ProMIS's resources for advancing its clinical programs and strategic initiatives.

18 Jan

3

An intrinsic calculation indicates that Phoenix Mecano AG (VTX:PMN) is undervalued by 44%. This assessment suggests that the company's stock price does not accurately reflect its underlying value, potentially presenting a buying opportunity for investors. Analysts are encouraged to consider this valuation in light of the company's financial health and market position. The undervaluation suggests a moderately noticeable influence on investor sentiment and market performance.

31 Dec

3

Phoenix Mecano (VTX:PMN) shareholders have achieved a 15% compound annual growth rate (CAGR) over the past three years, reflecting strong performance and investor confidence in the company's strategic direction and market positioning. The reported CAGR indicates a moderately positive influence on investor sentiment and financial performance.

18 Dec

4

ProMIS Neurosciences exceeds target enrollment in PRECISE-AD Phase 1b clinical trial of PMN310 for Alzheimer’s disease. Exceeding enrollment in Phase 1b Alzheimer’s trial accelerates PMN310 development timeline and enhances market sentiment for PMN.

4

ProMIS Neurosciences has successfully exceeded its target enrollment for the PRECISE-AD Phase 1b clinical trial of PMN310, a treatment for Alzheimer’s Disease. This milestone indicates strong interest and participation in the trial, which aims to evaluate the safety and efficacy of PMN310 in patients with early Alzheimer’s. The company is optimistic about the trial's potential outcomes and their implications for future Alzheimer’s treatments. Exceeding enrollment targets in a clinical trial can significantly enhance the company's prospects and investor sentiment regarding its Alzheimer's treatment.

12 Dec

3

Phoenix Mecano AG's recent stock performance is being driven by strong fundamentals, including robust financial results and strategic initiatives that enhance its market position. The company has shown resilience in its operations, leading to positive investor sentiment and increased stock value. Analysts are optimistic about its future growth prospects, attributing the performance to effective management and a solid business model. Strong fundamentals and positive investor sentiment may moderately influence the company's financial performance and market positioning.

10 Dec

4

ProMIS Neurosciences announced a new peer-reviewed publication that emphasizes the selective targeting of toxic oligomers, which may lead to potential clinical benefits and a reduced risk of ARIA (Amyloid-related imaging abnormalities). This research highlights the company's innovative approach in addressing neurodegenerative diseases, particularly Alzheimer's, by focusing on harmful protein aggregates. The publication could significantly enhance ProMIS Neurosciences' competitive positioning and investor sentiment in the neurodegenerative disease market.

1 Dec

4

ProMIS Neurosciences announced a new peer-reviewed publication demonstrating that plasma pTau can serve as a predictive early endpoint in Alzheimer's trials. This finding supports the company's ongoing Phase 1b PRECISE-AD trial with PMN310, potentially enhancing its research credibility and therapeutic development in the Alzheimer's space. The publication's findings could significantly influence the company's strategic direction and investor sentiment regarding its Alzheimer's drug development.

3

ProMIS Neurosciences will participate in the 8th Annual Evercore Healthcare Conference, providing an opportunity for the company to engage with investors and showcase its advancements in neuroscience research and drug development. Participation in a prominent healthcare conference can enhance visibility and investor interest, potentially influencing market sentiment.

24 Nov

3

ProMIS Neurosciences announced a reverse stock split aimed at increasing the per-share price of its common stock. The split ratio is set at 1-for-10, meaning shareholders will receive one new share for every ten shares they currently own. This decision is part of the company's strategy to meet the minimum bid price requirement for continued listing on the Nasdaq. The reverse split is expected to take effect on a specified date, and the company will notify shareholders of the details. The reverse stock split may influence market perception and compliance with listing requirements, but its overall impact on the company's trajectory is expected to be limited.

15 Nov

3

Promis Neurosciences is evaluating its capacity to invest in growth amid ongoing challenges in the biotech sector. The company is focusing on advancing its therapeutic candidates while managing financial resources effectively. Investors are keenly watching how these strategic decisions will impact the company's future performance and market positioning. The company's growth investment decisions may moderately influence its financial performance and competitive positioning.

12 Nov

4

ProMIS Neurosciences reported its financial results for the third quarter of 2025, highlighting key corporate developments and financial metrics. The company continues to advance its pipeline focused on neurodegenerative diseases, with updates on clinical trials and partnerships. Financial performance showed growth in revenue and investment in research and development, reflecting the company's commitment to innovation in therapeutic solutions. Significant advancements in clinical trials and partnerships could notably enhance the company's market position and investor sentiment.

7 Nov

4

Phoenix Mecano (VTX:PMN) is being highlighted for its potential to deliver significant returns, with analysts suggesting that the company's strategic initiatives and market positioning could lead to substantial growth. The firm is noted for its innovative products and strong market presence, which may attract investor interest and drive stock performance. Positive market sentiment surrounding PMN's future prospects is emphasized, indicating that it could be a promising investment opportunity. Significant strategic initiatives and market positioning are expected to influence the company's future performance.

3 Nov

3

ProMIS Neurosciences will participate in the Guggenheim 2nd Annual Healthcare Innovation Conference, showcasing its advancements in neuroscience and potential therapeutic solutions. The event will provide a platform for the company to engage with investors and industry leaders, highlighting its innovative approaches to treating neurodegenerative diseases. Participation in the conference may enhance visibility and investor interest, but its immediate impact on financial performance is expected to be limited.

22 Oct

3

ProMIS Neurosciences has appointed Slanix Paul Alex, Pharm.D., as a new board member. Alex is the President and Portfolio Manager of Public Equity at Ally Bridge Group, bringing extensive experience in investment and healthcare. This strategic addition aims to enhance the company's governance and support its growth initiatives in the biotechnology sector. The appointment of a seasoned professional to the board may positively influence the company's strategic direction and investor confidence.

22 Sep

3

Phoenix Mecano AG holds a 39% ownership stake in Promis Neurosciences, indicating significant insider investment and potential influence on the company's strategic direction. This level of ownership suggests that insiders are heavily invested in the company's success, which may impact decision-making and investor confidence. The article highlights the importance of insider ownership in assessing the company's future performance and market dynamics. Insider ownership at this level may moderately influence investor sentiment and company operations.

3 Sep

3

Promis Neurosciences (PMN) has been highlighted as one of the most active stocks in the market. The company is involved in developing therapies for neurodegenerative diseases, and its stock performance has garnered attention due to recent trading activity. Investors are closely monitoring PMN's developments as it navigates the competitive landscape of biotechnology. Recent trading activity indicates a moderate influence on investor sentiment and market performance.

stockrow.com/PMN · Data as of Dec 31, 2020 · For information only; not investment advice. · © 2026 stockrow.com